p. 1159−1172
2008-3874
Vol.24/No.9
p. 1173−1181
2008-3874
Vol.24/No.9
p. 1182−1189
2008-3874
Vol.24/No.9
C; p.Phe650Ser), a splicing (NM_001349864; c.1266-1G>A) and a frameshift variant (NM_003560.4; c.1547_1548dupCG; p.Gly517ArgfsTer29). Since the variants were not previously reported in literature or population databases, we performed in-silico studies for these variants and demonstrated their potential pathogenicity.Conclusion: The current study reports novel genetic variants in the PLA2G6 gene in the Iranian population, emphasizing the importance of high-throughput genetic testing in rare diseases.]]>
p. 1190−1195
2008-3874
Vol.24/No.9
p. 1196−1202
2008-3874
Vol.24/No.9
p. 1203−1210
2008-3874
Vol.24/No.9
p. 1211−1219
2008-3874
Vol.24/No.9
p. 1220−1230
2008-3874
Vol.24/No.9
p. 1231−1239
2008-3874
Vol.24/No.9
p. 1240−1246
2008-3874
Vol.24/No.9
p. 1247−1253
2008-3874
Vol.24/No.9
p. 1254−1263
2008-3874
Vol.24/No.9
p. 1264−1271
2008-3874
Vol.24/No.9
0.05). After NAcSh electrical stimulation or SB334867 ICV injection, the PF intake was significantly decreased in the DIO rats (p <0.05), and there was no significant difference after preadministration of BIC into LHA (P>0.05). Conclusion: This GABAergic pathway could regulate the expression of orexin-A in LHA and PF intake. Orexin-A neurons in LHA of DIO rats might be less sensitive to GABAergic signals and may consequently lead to more hedonic food intake.]]>
p. 1272−1278
2008-3874
Vol.24/No.9
p. 1279−1291
2008-3874
Vol.24/No.9
p. 1292−1300
2008-3874
Vol.24/No.9
p. 1301−1306
2008-3874
Vol.24/No.9