TY - JOUR ID - 11915 TI - Comparative virulotyping and phylogenomics of Escherichia coli isolates from urine samples of men and women suffering urinary tract infections JO - Iranian Journal of Basic Medical Sciences JA - IJBMS LA - en SN - 2008-3866 AU - Staji, Hamid AU - Rassouli, Maryam AU - Jourablou, Samaneh AD - Department of Pathobiology, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran AD - Graduated student (DVM), Faculty of Veterinary Medicine, Semnan University, Semnan, Iran Y1 - 2019 PY - 2019 VL - 22 IS - 2 SP - 211 EP - 214 KW - Female KW - Male KW - Phylogeny KW - Urinary tract infections KW - Uropathogenic Escherichia coli KW - Virulence DO - 10.22038/ijbms.2018.28360.6880 N2 - Objective(s): Escherichia coli strains are common pathogens that can cause urinary tract infections (UTI). This study aimed to assess E. coli phylogroups and virulence types in male and female UTI patients.Materials and Methods: In the present study, 160 uropathogenic E. coli (UPEC) isolates (from both sexes) were assigned to phylogroups/types and some extraintestinal virulence factors were detected within them by multiplex-PCR.Results: The isolates from women and men were predominantly distributed within phylogroup B2 and D, respectively. The presence of D2 phylotype was higher in men isolates than women, significantly (P=0.045). In male isolates papEF and sfa/focDE are more prevalent in B2 group than D, significantly (P=0.048; P=0.035). The prevalence of hly in B2 group is significantly higher than D (P=0.034) in female isolates.Conclusion: This study highlighted different features of E. coli genotypes from phylogenetic and virulence point of view implicated in UTI’s in both human genders. UR - https://ijbms.mums.ac.ir/article_11915.html L1 - https://ijbms.mums.ac.ir/article_11915_48b1d604059aecae94edd960863b2d54.pdf ER -