TY - JOUR ID - 2249 TI - The effects of whole green tea infusion on mouse urinary bladder chemical carcinogenesis JO - Iranian Journal of Basic Medical Sciences JA - IJBMS LA - en SN - 2008-3866 AU - Henriques, Andreia AU - Arantes-Rodrigues, Regina AU - Faustino-Rocha, Ana I AU - Teixeira-Guedes, Catarina I AU - Pinho-Oliveira, Jacinta AU - Talhada, Daniela AU - Teixeira, José H AU - Andrade, Andreia AU - Colaço, Bruno AU - Paiva-Cardoso, Maria N AU - Pires, Maria J AU - MVD Ferreira, Ana AU - Nunes, Fernando M AU - Oliveira, Paula A AD - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, Portugal AD - Department of Zootechnics, University of Trás-os-Montes and Alto Douro, 911 Vila Real, Portugal Center for the Study of Animal Sciences (CECA), University of Porto, 4485-661, Porto, PortugalCentre for the Research and Technology AD - Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, 5001-911, Vila Real, PortugalCenter for the Study of Animal Sciences (CECA), University of Porto, 4485-661, Porto, PortugalCentre for the Research and Technology AD - Chemistry Research Center, CQ-VR, University of Trás-os-Montes and Alto Douro, 5001-801, Vila Real, Portugal Y1 - 2014 PY - 2014 VL - 17 IS - 2 SP - 145 EP - 148 KW - green tea KW - Mice KW - N-butyl-N-(4-hydroxybutyl)nitro- samine KW - Urinary bladder cancer DO - 10.22038/ijbms.2014.2249 N2 - Objective(s):Green tea (GT) is one of the most popular beverages worldwide whose beneficial effects on health have been demonstrated. Recent studies suggest that GT may contribute to reduction of cancer risk and progression. The aim of this study was to evaluate the effects of whole GT on urinary bladder chemical carcinogenesis in male and female ICR mice. Materials and Methods: The GT characterization was performed using spectrophotometric methods. Urinary bladder lesions were induced using N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) by gavage during 10 weeks and whole GT (0.5%) was provided ad libitum during 20 weeks. Results:Animals from groups BBN+GT and BBN only developed preneoplastic lesions. Conclusion:We did not observe any effects by GT infusion administration on urinary bladder cancer development. UR - https://ijbms.mums.ac.ir/article_2249.html L1 - https://ijbms.mums.ac.ir/article_2249_a9261b7e390f95f5dd8a00fb0fb75503.pdf ER -