TY - JOUR ID - 5058 TI - ioactivity of Malva Sylvestris L., a Medicinal Plant from Iran JO - Iranian Journal of Basic Medical Sciences JA - IJBMS LA - en SN - 2008-3866 AU - Razavi, Seyed Mehdi AU - Zarrini, Gholamreza AU - Molavi, Ghader AU - Ghasemi, Ghader AD - Department of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran AD - Department of Animal Sciences, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran AD - Department of Statistics, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran Y1 - 2011 PY - 2011 VL - 14 IS - 6 SP - 574 EP - 579 KW - Antibacterial KW - Antifungal KW - Cytotoxicity KW - Malva sylvestris DO - 10.22038/ijbms.2011.5058 N2 - Objective(s) Malva sylvestris L. (Malvaceae), an annual plant, has been already commonly used as a medicinal plant in Iran. In the present work, we evaluate some bioactivities of the plant extracts. Materials and Methods The aired-dried plant flowers and leaves were extracted by soxhlet apparatus with n-hexane, dichloromethane and methanol. The antimicrobial, cytotoxic, and phytotoxic of the plant extracts were evaluated using disk diffusion method, MTT, and Lettuce assays, respectively. Results Both flowers and leaves of M. sylvestris methanol extracts exhibited strong antibacterial effects against Erwinia carotovora, a plant pathogen, with MIC value of 128 and 256 pg/ml, respectively. The flowers extract also showed high antibacterial effects against some human pathogen bacteria strains such as Staphylococcus aureus, Streptococcus agalactiae, Entrococcus faecalis, with MIC value of 192, 200 and 256 pg/ml, respectively. The plant methanol extracts had relatively high cytotoxic activity against MacCoy cell line. Conclusion We concluded that Malva sylvestris can be candidated as an antiseptic, a chemopreventive or a chemotherapeutic agent. UR - https://ijbms.mums.ac.ir/article_5058.html L1 - https://ijbms.mums.ac.ir/article_5058_8be770ff89bbe5c850b8716921f444a9.pdf ER -