en Original Article Bleeding, green tea, hemostasis, Polyvinyl alcohol, Tannin, Topical formulation 1085 1090 https://ijbms.mums.ac.ir/article_15949.html Fatemeh Kalalinia kalaliniaf@mums.ac.ir 67827 No Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran Nafise Amiri amirin901@mums.ac.ir 67821 No Department of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Niloufar Mehrvarzian mehrvn931@mums.ac.ir 67820 No Department of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Bibi Sedigheh Fazly Bazzaz fazlis@mums.ac.ir 67822 No Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran|School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Mehrdad Iranshahi iranshahim@mums.ac.ir 67823 No Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran Azadeh Shahroodi shahroudiaz3@mums.ac.ir 67824 No Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran|Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Sepideh Arabzadeh arabzadehs1@mums.ac.ir 67825 No Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran Mohammadreza Abbaspour abbaspourmr@mums.ac.ir 67826 No Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran|Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Shapour Badiee Aaval 67832 No Complementary Medicine Research Center, Faculty of Traditional Medicine, Mashhad University of Medical Sciences, Mashhad, lran Jebrail Movaffagh movaffaghj@mums.ac.ir 67819 Yes Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran|Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran