en Original Article Breast Cancer, Cellular spheroid, chemotherapy, Exosome, Natural killer cells 1604 1615 https://ijbms.mums.ac.ir/article_24757.html Zahra Sadat Hashemi z.hashemi@acecr.ac.ir 108582 Yes ATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran Mahlegha Ghavami m.ghavami1983@gmail.com 108583 No Pathology Department, Dalhousie University, Halifax, Canada Fateme Mohammadi fa-mohammmadi@razi.tums.ac.ir 108584 No Department of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran Mahdieh Shokrollahi Barough mahdie_shokrollahy@yahoo.com 108585 No ATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran Farhad Shokati farhad.shokati1@gmail.com 108586 No Biomaterials and Tissue Engineering Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran Saber Asghari asghari.sbr@gmail.com 108587 No ATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran saeed khalili saeed.khalili@sru.ac.ir 108588 No Department of Biology Sciences, Shahid Rajaee Teacher Training University, Tehran, Iran Mandana Akbari Yekta 108591 No Biomaterials and Tissue Engineering Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran Ardeshir Ghavamzadeh cancer.celltherapy@gmail.com 108589 No Cancer and Cell Therapy Research Center, Tehran University of Medical Sciences, Tehran, Iran Ramin Sarrami Forooshani sarrami@acecr.ac.ir 108590 No ATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran