Iranian Journal of Basic Medical Sciences

en In vitro effects of phytochemicals on adipogenesis with a focus on molecular mechanisms: A systematic review Review Article Adipogenesis, In vitro models, Molecular mechanism, Obesity, Phytochemicals, Systematic review 401 417 https://ijbms.mums.ac.ir/article_25564.html Niusha Kazemi niusha.kazemi7@gmail.com 112182 No Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Elham Ramazani e.ramazani_bio@yahoo.com 112183 No Department of Biology, Yazd University, Yazd, Iran Zahra Tayarani-Najaran tayaraninz@mums.ac.ir 112184 Yes Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

en Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway Original Article Akt, Apoptosis, Autophagy, GBM, PI3K, Proliferation, Vortioxetine 418 425 https://ijbms.mums.ac.ir/article_25513.html Huan-Qi Zhang 871899896@qq.com 111982 No Research Center for Clinical Pharmacy, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China|Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310006, China Dao-Ming Zhang 22219159@zju.edu.cn 111983 No Research Center for Clinical Pharmacy, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China|Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310006, China Zhi-Zhen Huang 22419160@zju.edu.cn 111984 No Research Center for Clinical Pharmacy, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China|School of Medicine, Hangzhou City University, Hangzhou 310015, China Jing Cheng 22219147@zju.edu.cn 111985 No Research Center for Clinical Pharmacy, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China|School of Medicine, Hangzhou City University, Hangzhou 310015, China Chong Zhang zhangchong@hzcu.edu.cn 111986 No School of Medicine, Hangzhou City University, Hangzhou 310015, China Neng-Ming Lin lnm1013@163.com 111987 No Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310006, China Yang-Ling Li liyangling1215@163.com 111988 Yes Department of Clinical Pharmacology, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou 310006, China

en Melittin alleviates bleomycin-induced pulmonary fibrosis in vivo through regulating TGF-β1/Smad2/3 and AMPK/SIRT1/PGC-1α signaling pathways Original Article Epithelial-mesenchymal transition, Melittin, Mitochondria, Oxidative stress, Pulmonary Fibrosis 426 433 https://ijbms.mums.ac.ir/article_25234.html Jiawang Yu 20201225@wnmc.edu.cn 110738 No The Fifth Clinical Medical College of Anhui Medical University, Hefei, 230032, China|EICU, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241000, China WeiHua Lu lwh683@126.com 110739 Yes The Fifth Clinical Medical College of Anhui Medical University, Hefei, 230032, China|ICU, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241000, China

en Bioinformatics analysis identifies dysregulation of MiR-548F-3p and its hub gene in triple-negative breast cancer Original Article Computational biology, Gene expression profiling, microRNAs, Survival analysis, Triple negative breast - neoplasms 434 443 https://ijbms.mums.ac.ir/article_25445.html Samira Behroozi behroozisamira@yahoo.com 111641 No National Institute of Genetic Engineering and Biotechnology (NIGEB), Institute of Medical Biotechnology, Department of Medical Genetics, Tehran, Iran Mahdieh Salimi salimi@nigeb.ac.ir 111642 Yes National Institute of Genetic Engineering and Biotechnology (NIGEB), Institute of Medical Biotechnology, Department of Medical Genetics, Tehran, Iran Najaf Allahyari Fard allahyar@nigeb.ac.ir 111643 No National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran

en Pre- and post-traumatic boric acid therapy prevents oxidative stress-mediated neuronal apoptosis in spinal cord injury Original Article Apoptosis, Boric acid, Neuroprotective, Oxidative stress, Spinal cord injury 444 450 https://ijbms.mums.ac.ir/article_25270.html Turan Kandemir turankandemir26@gmail.com 110938 Yes Department of Neurosurgery, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey İbrahim Söğüt ibrahim.sogut@gmail.com 110939 No Department of Biochemistry, Demiroglu Bilim University, Medical Faculty, Istanbul, Turkey Zeki Serdar Ataizi sataizi@gmail.com 110940 No Department of Neurosurgery, Eskişehir Yunus Emre State Betül Can betul_cn@yahoo.com 110941 No Department of Medical Biochemistry, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey Ayşegül Oğlakçı İlhan ayseguloi@karatekin.edu.tr 110942 No Department of Medical Laboratory Techniques, Eldivan Health Services Vocational School, Cankırı Karatekin University, Cankırı, Turkey Dilek Burukoglu Donmez dburukoglu@yahoo.com 110943 No Department of Histology and Embryology, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey Güngör Kanbak gkanbak@ogu.edu.tr 110944 No Department of Medical Biochemistry, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey

en Alpha-pinene ameliorates liver fibrosis by suppressing oxidative stress, inflammation, and the TGF-β/Smad3 signaling pathway Original Article Alpha-pinene, Carbon tetrachloride, Collagen, Glutathione, Inflammation, Toll-like receptor 4 451 460 https://ijbms.mums.ac.ir/article_25488.html Fatemeh Noroozi farzaneh.norouzi17@gmail.com 111836 No Department of Physiology, Zanjan Branch, Islamic Azad University, Zanjan, Iran Masoumeh Asle Rousta mrousta58@gmail.com 111837 Yes Department of Physiology, Zanjan Branch, Islamic Azad University, Zanjan, Iran Rahim Amini rahimamini84@gmail.com 111838 No Department of Biology, Zanjan Branch, Islamic Azad University, Zanjan, Iran Zeinab Sahraeian biosahraeian58@gmail.com 111839 No Nanobiotechnology Research Center, Zanjan Branch, Islamic Azad University, Zanjan, Iran

en Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats Original Article Apoptosis, Cytokines, Diabetes Mellitus, Inflammation, Lycopene, Signal transduction 461 468 https://ijbms.mums.ac.ir/article_25548.html Ozlem Ozmen ozlemoz@mehmetakif.edu.tr 112119 No Department of Pathology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Türkiye Melda Şahin meldasahin0510@gmail.com 112120 Yes Department of Pathology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Türkiye Senay Topsakal stopsakal@pau.edu.tr 112121 No Department of Endocrinology and Metabolism,University, Pamukkale Faculty of Medicine, Denizli, Türkiye Şerife Taşan vethekserifeagirca@gmail.com 112122 No Department of Pathology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Türkiye Uğur Şahi̇n ugursahin@sdu.edu.tr 112123 No Genetic Research Unit, Innovative Technologies Application and Research Center, Süleyman Demirel University, Isparta, Türkiye

en Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice Original Article Exosome, Immunomodulation, Mice, Mesenchymal stem cells, Regeneration, Transplantation 469 476 https://ijbms.mums.ac.ir/article_25466.html Parham Soufizadeh soufizadehparham@ut.ac.ir 111733 No Biomedical Research Institute, University of Tehran, Tehran, Iran|Gene Therapy Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran Gholamreza Nikbakht Brujeni nikbakht@ut.ac.ir 111734 Yes Biomedical Research Institute, University of Tehran, Tehran, Iran|Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Mohammad Mehdi Dehghan mdehghan@ut.ac.ir 111735 No Biomedical Research Institute, University of Tehran, Tehran, Iran|Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Massoumeh Jabbari Fakhr mjabbarifakhr@gmail.com 111736 No Biomedical Research Institute, University of Tehran, Tehran, Iran|Department of Tissue Engineering and Applied Cell Sciences, School of Medicine, Qom University of Medical Sciences, Qom, Iran Pouya Houshmand p.houshmand95@gmail.com 111737 No Biomedical Research Institute, University of Tehran, Tehran, Iran|Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Mahyar Mohebbi mahyarmohebi.mm@gmail.com 111738 No Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Hossein Aminianfar aminianfar@ut.ac.ir 111739 No Biomedical Research Institute, University of Tehran, Tehran, Iran|Department of Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Sirous Sadeghian Chaleshtori s.sadeghian@ut.ac.ir 111740 No Biomedical Research Institute, University of Tehran, Tehran, Iran|Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

en SIRT5 prevents mitochondrial dysfunction and cardiac hypertrophy induced by RIP140 Original Article Cardiac hypertrophy, Energy metabolism, Mitochondria, RIP140, SIRT5 477 485 https://ijbms.mums.ac.ir/article_25268.html Liying Liang 1137984433@qq.com 110929 No Department of Pharmacy, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China Yi Huang 909314624@qq.com 110930 No Guangzhou Special Service Recuperation Center of PLA Rocket Force, Guangzhou, Guangdong, China Qiujuan Wang 2411288144@qq.com 110931 No Department of Pharmacy, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China Ye Hong hongyezcc@163.com 110932 No Department of Pharmacy, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China Honghui Zhen 953156864@qq.com 110933 No Department of Pharmacy, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China Yanfang Chen yfchen312@126.com 110934 Yes Department of Pharmacy, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China

en Glutamate receptors within the lateral periaqueductal gray (lPAG): Effects on blood pressure and heart rate in basic and hypotensive hemorrhagic rats Original Article Cardiovascular system, Glutamate, Hemorrhage, Lateral periaqueductal gray, Non-NMDA receptor 486 492 https://ijbms.mums.ac.ir/article_25563.html Vida Alikhani alikhaniv4013@mums.ac.ir 112179 No Department of Physiology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran Reza Mohebbati mohebbatir@mums.ac.ir 112180 No Department of Physiology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran|Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Mohammad Naser Shafei shafeimn@mums.ac.ir 112181 Yes Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran|Division of Neurocognitive Sciences, Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

en Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression Original Article Akt, BDNF, Depression, Ellagic acid, PI3K 493 497 https://ijbms.mums.ac.ir/article_25442.html Aslı Hatice Bedel aslibedel@sdu.edu.tr 111632 No Süleyman Demirel University Faculty of Pharmacy Department of Pharmacology, Türkiye|Akdeniz University Faculty of Medicine Department of Medicinal Pharmacology, Türkiye Coskun Usta fcusta@akdeniz.edu.tr 111633 Yes Akdeniz University Faculty of Medicine Department of Medicinal Pharmacology, Türkiye

en In vitro and in vivo evaluation of photo-induced antileishmanial activity of indocyanine green-loaded nanomicelles Original Article Leishmania major, Nanomedicine, Photodynamic Therapy (PDT), Photosensitizer, Photothermal therapy (PTT) 498 506 https://ijbms.mums.ac.ir/article_25489.html Shirin Jalili jalili.shirin@yahoo.com 111840 No Institute of Police Equipment and Technologies, Policing Sciences and Social Studies Research Institute, Tehran, Iran Jafar Mosafer mosaferj901@gmail.com 111841 No Research Center of Advanced Technologies in Medicine, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran|Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran Seyed Amin Mousavinezhad mousavinezhad101@gmail.com 111842 No Research Center for Life & Health Sciences & Biotechnology of the Police, Directorate of Health, Rescue & Treatment, Police Headquarters, Tehran, Iran Ameneh Sazgarnia sazgarniaa@mums.ac.ir 111843 No Medical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Mohammad Ali Mohaghegh mohaghegh1982@yahoo.com 111844 No Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran|Department of Laboratory Sciences, School of Paramedical Sciences, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran Mehdi Hoseini hoseini.mehdi98@gmail.com 111845 Yes Department of Radiology Technology, School of Paramedical Sciences, Torbat Heydarieh University of Medical Sciences, Torbat Heydarieh, Iran

en Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways Original Article Apoptosis, Diclofenac, Endoplasmic reticulum stress, Inflammation, Morin, Oxidative stress 507 515 https://ijbms.mums.ac.ir/article_25503.html Hasan Şimşek hasansimsek47@hotmail.com 111909 Yes Department of Physiology, Faculty of Medicine, Aksaray University, Aksaray, Türki̇ye Nurhan Akaras nurhanakaras@aksaray.edu.tr 111910 No Department of Histology and Embryology, Faculty of Medicine, Aksaray University, Aksaray, Türki̇ye Cihan Gur cihan.gur@atauni.edu.tr 111911 No Department of Medical Laboratory Techniques, Vocational School of Health Services, Atatürk University, Erzurum, Türki̇ye Sefa Kucukler sefa.kucukler@atauni.edu.tr 111912 No Department of Veterinary Biochemistry, Faculty of Veterinary, Atatürk University, Erzurum, Türki̇ye Mustafa Ileriturk m.ileriturk@atauni.edu.tr 111913 No Department of Animal Science, Horasan Vocational College, Atatürk University, Erzurum, Türki̇ye Fatih Mehmet Kandemir fmkandemir@aksaray.edu.tr 111914 No Department of Medical Biochemistry, Faculty of Medicine, Aksaray University, Aksaray, Türki̇ye

en Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin Original Article Chrysin, Dipeptidyl peptidase 8, Dipeptidyl peptidase 9, Inflammatory - osteoclastogenesis, M1 macrophage, RAW264.7 cells 516 526 https://ijbms.mums.ac.ir/article_25487.html Syed Sufian Ahmad sufsahmad22@gmail.com 111832 No Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard, New Delhi – 110062, India Faraha Ahmed ahmedfaraha@gmail.com 111833 No Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard, New Delhi – 110062, India Sayeed Ahmad sahmad_jh@yaho.co.in 111834 No Bioactive Natural Product Laboratory, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard, New Delhi – 110062, India Anuja Krishnan anujabala@hotmail.com 111835 No Department of Molecular Medicine, School of Interdisciplinary Science and Technology, Jamia Hamdard, Hamdard, New Delhi – 110062, India Mohammad Ahmed Khan khan.ahmed1511@gmail.com 111831 Yes Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard, New Delhi – 110062, India

en Role of ENaC in gender-associated differences in blood pressure Original Article Castration, Epithelial sodium channel, Hypertension, Lysine-deficient protein - kinase, Sex differences 527 532 https://ijbms.mums.ac.ir/article_25443.html Guo-feng Yu 6517096@zju.edu.cn 111635 No Department of Clinical Laboratory, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China, 310052 Li-qin Yu 994304702@qq.com 111636 No Qiaosi Branch, First People’s Hospital of Linping District, Hangzhou, Zhejiang Province, China Qin-rui Lai 22318126@zju.edu.cn 111637 No Department of Clinical Laboratory, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China, 310052 Wei Li chweige@zju.edu.cn 111634 Yes Department of Clinical Laboratory, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China, 310052

en Corrigendum: MicroRNA miR-188-5p enhances SUMO2/3 conjugation by targeting SENP3 and alleviates focal cerebral ischemia/reperfusion injury in rats Corrigendum 0 0 https://ijbms.mums.ac.ir/article_25608.html