Iranian Journal of Basic Medical Sciences

en Phenotypic alterations in the immune system and tolerance induction in tumor-draining lymph nodes Review Article Cellular reprogramming, Immune tolerance, Neoplasm metastasis, Sentinel lymph nodes, Tumor Microenvironment 488 497 https://ijbms.mums.ac.ir/article_27359.html Zohreh Koohini z.koohini@gmail.com 120155 Yes Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Mansoureh Karimi Kakh m.kk1992@yahoo.com 120156 No Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Zeinab Rajabian rajabianzeinab@yahoo.com 120157 No Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Zahra Koohini zozohi1212@gmail.com 120158 No Department of Medical Genetics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

en Ultrasound medicine in the era of precision theranostics: Mechanisms, molecular strategies, and clinical translation Review Article High-intensity focused-ultrasound, Low-intensity pulsed-ultrasound, Molecular imaging, Sonoporation, Theranostics, Ultrasound 498 521 https://ijbms.mums.ac.ir/article_27392.html Lei Wang wanglei198573@163.com 120330 No Affiliated Hospital of Jinggangshan University, Ji’an Jiangxi, 343000, China Zhiyu Luo zhiyu.luo1200@gmail.com 120331 Yes Affiliated Hospital of Jinggangshan University, Ji’an Jiangxi, 343000, China Dan Liu liudan198192@163.com 120332 No Jinggangshan University, Ji’an Jiangxi, 343009, China

en Cannabidiol: Pharmaceutical formulations and biomedical applications Review Article Cannabidiol, Cannabis sativa, Intranasal delivery, Nanotechnology, Oral delivery, Pulmonary delivery, Transmucosal delivery 522 530 https://ijbms.mums.ac.ir/article_27439.html Ali Fadavi Eslam ali_fadavieslam@yahoo.com 120510 No Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Leila Mohtashami mohtashamil@mums.ac.ir 120511 No Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Parvin Moghimi parvinmoghimi68@gmail.com 120512 No Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran Mehrdad Iranshahi iranshahim@mums.ac.ir 120513 Yes Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

en Targeting amyloid-β in Alzheimer’s disease: A critical analysis of clinical trials and their implications for drug development Review Article γ-Secretase, Aβ, Alzheimer’s disease, APP, BACE1, Small-molecule drugs 531 543 https://ijbms.mums.ac.ir/article_27372.html Mengyu Han 13665675695@163.com 120219 No Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan province, China Zhonghua Li lizh@hactcm.edu.cn 120220 Yes Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan province, China Tiancheng Sun 18337897180@163.com 120221 No Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan province, China Bingyu Xiao 15515677282@163.com 120222 No Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan province, China Jiaxin Zhang m17838807176@163.com 120223 No Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan province, China Sijia Liu 15836772615@163.com 120224 No Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan province, China Jige Yang y15638418801@163.com 120225 No Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan province, China Jinlian Ma lianzi556@163.com 120226 No Collaborative Innovation Center of Prevention and Treatment of Major Diseases by Chinese and Western Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China Pan Wang w.p1008@hotmail.com 120227 No Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan province, China|Collaborative Innovation Center of Prevention and Treatment of Major Diseases by Chinese and Western Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan Province, China

en Characterization of exosomes from hypoxia-activated human amniotic membrane mesenchymal stem cells Original Article Amniotic membrane, Biocompatibility, Extracellular vesicles, Hypoxia, Mesenchymal stem cells, Exosomes 544 557 https://ijbms.mums.ac.ir/article_27395.html Hadiseh Kholgh kholghhadiseh@gmail.com 120340 No Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran Fatemeh Eshghabadi f.eshghabadi@ut.ac.ir 120341 No Department of Life Science Engineering, College of Interdisciplinary Science and Technology, University of Tehran, Tehran, Iran Hanieh Jafary jafaryh8287@gmail.com 120342 No Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran Kavosh Zandsalimi kavosh.bme@yahoo.com 120343 No Department of Medical Laser (MLRC), Medical Laser Research Center, Yara Institute, ACECR, Tehran, Iran Nazanin Akbari nazaninakbarii000@gmail.com 120344 No Department of Biology, Shahid Beheshti University, Tehran, Iran Azadeh Soltani azadehsoltani21@yahoo.com 120345 No Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran Banafsheh Heidari ban_heidari@yahoo.com 120346 Yes Department of Regenerative Medicine in Wound Healing, Medical Laser Research Center, Yara Institute, ACECR, Tehran, Iran

en Remote ischemic preconditioning protects heart via modulation of purinergic signaling and AMPK-mediated autophagy in rat model of ischemia reperfusion injury Original Article Adenosine A1 receptor AMP-activated protein- kinase, Autophagy, Cardioprotection, MIRI, Remote ischemic-preconditioning 558 569 https://ijbms.mums.ac.ir/article_27397.html Kuldeep Kumar kuldeepsharmaa1987@gmail.com 120350 No Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, (Punjab)-147002, India|Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), New Delhi-110029-India Harlokesh Narayan Yadav hnyadav@gmail.com 120351 No Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), New Delhi-110029-India Nirmal Singh nirmal_puru@rediffmail.com 120352 Yes Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, (Punjab)-147002, India

en Trans sodium crocetinate protects against hepatotoxicity induced by bisphenol A in rats Original Article Anti-oxidant, Apoptosis, Bisphenol A, Oxidative stress, Trans sodium crocetinate 570 577 https://ijbms.mums.ac.ir/article_27396.html Majid keshavarzi keshavarzim2@mums.ac.ir 120348 No Department of Pharmacodynamics and Toxicology, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Bibi Marjan Razavi razavimr@mums.ac.ir 120347 Yes Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran|Department of Pharmacodynamics and Toxicology, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Hossein Hosseinzadeh hosseinzadehh@mums.ac.ir 120349 No Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran|Department of Pharmacodynamics and Toxicology, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

en Impact of TGF-β and ERK1/2 inhibition on preimplantation embryo development and quality Original Article Mitogen-activated protein kinases/Extracellular signal-regulated kinases, PD0325901, Pre-implantation embryo, SB431542, Transforming growth factor- beta 578 589 https://ijbms.mums.ac.ir/article_27437.html Faezah Mohammadi Ghazani faezeh_mohammadi_65@yahoo.com 120498 No Faculty of Development of Biology, University of Science and Culture, Tehran, Iran|Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran Fatemeh Shirvanizadeh shirvanizadehfatemeh@yahoo.com 120499 No Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran Seyedeh-Nafiseh Hassani nafiseh.hassani@royaninstitute.org 120500 No Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran Azam Dalman dalman79@yahoo.co.uk 120501 No Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran Nahid Nasiri anahid.1333@yahoo.com 120502 No Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran|Department of Photo Healing and Regeneration, Medical Laser Research Center, Yara Institute Academic Center for Education, Culture and Research (ACECR), Tehran, Iran Maryam Zarei maryam.zareei@gmail.com 120503 No Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran Saman Maroufizadeh saman.maroufizadeh@gmail.com 120504 No Department of Biostatistics and Epidemiology, School of Health, Guilan University of Medical Sciences, Rasht, Iran Poopak Eftekhari Yazdi eftekhari@royaninstitute.org 120505 Yes Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

en Dexmedetomidine protects against ischemia and reperfusion-induced kidney injury in rats by inhibiting the expression of TRPM2 and TRPA1 channels Original Article Dexmedetomidine, Ischemia/Reperfusion, Kidney, TRPA1, TRPM2 590 597 https://ijbms.mums.ac.ir/article_27455.html Abdulkadir Uzunboy akuzunboy@hotmail.com 120595 No Department of Anesthesiology and Reanimation, Faculty of Medicine, Firat University, Elazig, Turkiye Tuncay Kuloglu tkuloglu@firat.edu.tr 120596 No Department of Histology and Embryology, Faculty of Medicine, Firat University, Elazig, Turkiye Oguzhan Demirel demireloguzhan1@gmail.com 120597 No Department of Anesthesiology and Reanimation, Faculty of Medicine, Ankara University, Ankara, Turkiye Ahmet TURK aturk@adiyaman.edu.tr 120598 No Department of Histology and Embryology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkiye Gulsum Altuntas galtuntas@firat.edu.tr 120600 No Department of Anesthesiology and Reanimation, Faculty of Medicine, Firat University, Elazig, Turkiye Esef Bolat esefbolat@hotmail.com 120599 Yes Department of Anesthesiology and Reanimation, Faculty of Medicine, Firat University, Elazig, Turkiye

en Comparison of long non-coding RNA NEAT1 expression, P53, and antioxidant factors between Alzheimer’s patients and healthy individuals Original Article Alzheimer disease RNA, Apoptosis, Long non-coding, NEAT1, Oxidative stress 598 604 https://ijbms.mums.ac.ir/article_27441.html Sara Yarahmadi sara.yarahmadiii75@gmail.com 120517 No Department of Physiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran|Cellular and molecular research center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Leila Alidoust alidoust57@gmail.com 120518 No Department of Genetics, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Alia Saberi alia.saberi@gmail.com 120519 No Neuroscience Research Center, Trauma Institute, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Behrooz Khakpour-Taleghani khakpour_b@yahoo.com 120520 No Department of Physiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran|Neuroscience Research Center, Trauma Institute, Poursina Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Mohamad Rostampour rost_v@yahoo.com 120521 No Department of Physiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran|Cellular and molecular research center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Adele Jafari jafari.adele@gmail.com 120522 Yes Department of Physiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran

en Norepinephrine promotes the proliferation, migration, and phenotypic transformation of renal artery vascular smooth muscle cells via ROCK1 Original Article Hypertensive nephropathy, Mitochondrial fission, Norepinephrine, Rho-associated kinase, Vascular smooth muscle- cells 605 612 https://ijbms.mums.ac.ir/article_27453.html Sixuan Chen chensixuan2022@163.com 120575 No Department of Cardiology,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China|Department of Geriatrics,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China Lina Wang 13351000102@163.com 120576 No Department of Geriatrics,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China Lu Wang 2023020963@hrbmu.edu.cn 120577 No Department of Geriatrics,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China Hui Li hli0314@163.com 120578 No Department of Geriatrics,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China Junyao Lu 18904804803@163.com 120579 No The Key Laboratory of Cardiovascular Disease Acousto-Optic Electromagnetic Diagnosis and Treatment in Heilongjiang Province, The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China Yaxin He 17838825710@163.com 120580 No Department of Geriatrics,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China Yihong Zhang 1042803526@qq.com 120581 No Department of endocrinology, Heilongjiang Province Hospital, Harbin 150088, China Yuanyuan Guo guoyuanyuan@hrbmu.edu.cn 120582 Yes Department of Cardiology,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China|Department of Geriatrics,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China|The Key Laboratory of Cardiovascular Disease Acousto-Optic Electromagnetic Diagnosis and Treatment in Heilongjiang Province, The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China Mingyu Liu liumingyu0504@126.com 120583 Yes Department of Cardiology,The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China|The Key Laboratory of Cardiovascular Disease Acousto-Optic Electromagnetic Diagnosis and Treatment in Heilongjiang Province, The First Affiliated Hospital, Harbin Medical University, Harbin 150088, China

en The effect(s) of berberine from Berberis vulgaris L. (Berberidaceae) on treating type 1 diabetes mellitus in streptozotocin-induced diabetic rats Original Article Berberine, Diabetes mellitus type 1, Streptozocin, Gamma-aminobutyric acid, Gastrins, Islets of Langerhans 613 622 https://ijbms.mums.ac.ir/article_27440.html Hossein Salmanizadeh h.salmanizadeh@ut.ac.ir 120515 No Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran Razieh Yazdanparast ryazdan@ut.ac.ir 120514 Yes Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran Mustafa Ghanadian ghanadian@pharm.mui.ac.ir 120516 No Department of Pharmacognosy, Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

en Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats Original Article Apoptosis, Doxorubicin, Gallic acid, Inflammation, Molecular docking, Nephrotoxicity, Oxidative stress 623 633 https://ijbms.mums.ac.ir/article_27454.html Samet Teki̇n samet.tekin@atauni.edu.tr 120584 Yes Atatürk University, Faculty of Veterinary Medicine, Department of Physiology, 25000 Erzurum, Turkey Burak Çinar burakcinar@atauni.edu.tr 120585 No Atatürk University, Faculty of Medicine, Department of Medical Pharmacology, 25000 Erzurum, Turkey Yusuf Dağ yusuf_dag02@hotmail.com 120586 No Atatürk University, Faculty of Veterinary Medicine, Department of Physiology, 25000 Erzurum, Turkey Aslıhan Atasever aslihan.atasever@erzincan.edu.tr 120587 No Atatürk University, Faculty of Veterinary Medicine, Department of Physiology, 25000 Erzurum, Turkey Merve Bolat mervebolat@atauni.edu.tr 120588 No Atatürk University, Faculty of Veterinary Medicine, Department of Physiology, 25000 Erzurum, Turkey İsmail Bolat ismail.bolat@atauni.edu.tr 120589 No Atatürk University, Faculty of Veterinary Medicine, Department of Pathology, 25000 Erzurum, Turkey Burak Batuhan Laçi̇n bblacin@atauni.edu.tr 120590 No Atatürk University, Faculty of Veterinary Medicine, Department of Physiology, 25000 Erzurum, Turkey Emin Şengül emin.sengul@atauni.edu.tr 120591 No Atatürk University, Faculty of Veterinary Medicine, Department of Physiology, 25000 Erzurum, Turkey Serkan Yıldırım syildirim@atauni.edu.tr 120592 No Atatürk University, Faculty of Veterinary Medicine, Department of Physiology, 25000 Erzurum, Turkey|Kyrgyzstan-Turkey Manas University, Faculty of Veterinary Medicine, Department of Pathology, 720007 Bishkek, Kyrgyzstan Mohamad Warda mohamad.warda@atauni.edu.tr 120593 No Atatürk University, Faculty of Veterinary Medicine, Department of Physiology, 25000 Erzurum, Turkey|Cairo University, Faculty of Veterinary Medicine, Department of Biochemistry, 3753450 Giza, Egypt

en Synergistic induction of apoptosis in cancer cells by combined silver nanoparticles and paclitaxel Original Article Apoptosis, Hela Cells, Nanoparticles, Paclitaxel, Silver, Uterine Cervical Neoplasms 634 640 https://ijbms.mums.ac.ir/article_27438.html Alireza Shams dr.shams@abzums.ac.ir 120506 Yes Department of Anatomy, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran Mohammad amin Shams aminshamsrh@gmail.com 120507 No School of Medicine, Iran University of Medical Sciences, Tehran, Iran Maryam Amirinejad amiri.mm69@gmail.com 120508 No Department of Anatomy, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran Ghazale Molaverdi 120509 No Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran