Essential oils chemical composition, antioxidant activities and total phenols of Astrodaucus persicus

Document Type: Original Article

Authors

Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Objective(s):Astrodaucus persicus, Apiaceae, is used as vegetable or food additive in some parts of Iran. The essential oils of different parts of Astrodaucus persicus from Kordestan province were analyzed for the first time and compared with other regions. In this study, antioxidant activities and total phenols determination of aerial parts essential oils and root fractions of A. persicus were investigated.
Materials and Methods: The essential oils were obtained by hydro-distillation from flowers/fruits, leaves/stems, ripe fruits and roots of plant and analyzed by GC-MS. Crude root extract was fractionated with hexane, chloroform, ethyl acetate and methanol. Antioxidant activities by DPPH and FRAP methods and total phenols by Folin-ciocalteu assay were measured.
Results: The abundant compounds of flowers/fruits blue essential oil were α-thujene, β-pinene and α-pinene. The predominant components of blue leaves/stems essential oil were α-thujene, α-pinene and α-fenchene. The major volatiles of ripe fruits blue essential oil were β-pinene, α-thujene and α-pinene. The chief compounds of root yellow essential oil were trans-caryophyllene, bicycogermacrene and germacrene-D. Total root extract and ethyl acetate fraction showed potent antioxidant activities and high amount of total phenols in comparison to other samples. Among volatile oils, the flowers/fruits essential oil showed potent reducing capacity.
Conclusion: The major compounds of aerial parts essential oils were hydrocarbon monoterpenes while the chief percentage of roots essential oil constituents were hydrocarbon sesquiterpenes. α-Eudesmol and β-eudesmol were identified as responsible for creation of blue color in aerial parts essential oils. A. persicus was known as a potent antioxidant among Apiaceae.

Keywords


1. Bazargani YT, Almasirad A, Amin G, Shafiee A. Chemical composition of the essential oils of Astrodaucus persicus (Boiss.) Drude root, stem/leaves and flowers/fruits. Flavour Fragr J 2006; 21:294-296.

2. Nazemiyeh H, Razavi SM, Delazar A, Asnaashari S, Khoi NS, Daniali S, et al. Distribution Profile of Volatile Constituents in Different Parts of Astrodaucus orientalis (L.) Drude.  Rec Nat Prod 2009; 3:126-130.

3. Yildirim E, Dursun A, Turan M. Determination of the Nutrition Contents of the Wild Plants Used as Vegetables in Upper Coruh Valley. Turk J Bot 2001; 25:367-371.

4. Bigdeli M, Rustaiyan A, Ameri N, Masoudi Sh. Essential Oil of Astrodaucus persicus (Boiss.) Drude. from Iran.  J  Essent Oil Res 2014; 16:420-421.

5. Omidbaigi R, Bastan MR, Omidbaigi MA.  Essential oil content and chemical composition of Astrodaucus persicus Boiss cultivated in Iran. J Essent Oil Bear Pl 2005; 8:334-336.

6. Mirza M, Baher Nik Z, Dini M. Chemical composition of the essential oils of Astrodaucus orientalis (L.) Drude leaves and seeds. Flavour Fragr J 2003; 18:205–206.

7. Mazloomifar H, Bigdeli M, Saber-Tehrani M, Rustaiyan A, Masoudi Sh. Essential oil of Astrodaucus orientalis (L.) Drude. J Essential Oil Res 2013; 15:254-256.

8. Abdolmohammadi MH, Fouladdel Sh, Shafiee A, Amin Gh, Ghaffari SM, Azizi E. Anticancer effects and cell cycle analysis on human breast cancer T47D cells treated with extracts of Astrodaucus persicus (Boiss.) Drude in comparison to doxorubicin. Daru 2008; 16:112-118.

9. Azizi E, Abdolmohammadi MH, Fouladdel Sh, Shafiee A, Amin Gh, Ghaffari SM. Evaluation of p53 and Bcl-2 genes and proteins expression in human breast cancer T47D cells treated with extracts of Astrodaucus persicus (Boiss.) Drude in comparison to Tamoxifen, Immunocytochemistry. Daru 2009; 17:181-186.

10. Abdolmohammadi MH, Fouladdel S, Shafiee A, Amin G, Ghaffari SM, Azizi E. Antiproliferative and apoptotic effect of Astrodaucus orientalis (L.) drude on T47D human breast cancer cell line: Potential mechanisms of action. Afr J Biotechnol 2009; 8:4265-4276.

11. Razavi SM, Imanzadeh G, Dolati S, Nejad-Ebrahimi S, Majrouhi AA, Zahri S, et al. Phytochemical prospection and biological activity of Astrodaucus orientalis (L.) Drude growing wild in Iran. Pharmacologia 2011; 2:299-303.

12. Soltani J, Aliabadi A. Antibacterial effects of several plant extracts and essential oils on Xanthomonas arboricola pv. juglandis in vitro. J  Essent Oil Bear Plant 2013; 16:461-468.

13. Adams RP. Identification of essential oil components by gas chromatography/ quadrupole mass spectroscopy. Allured Publishing Co. Carol Stream Illinois USA: 2001.

14. Massada Y. Analysis of essential oil by gas chromatography and spectrometry. Wiley, New York, USA: 1976.

15. Yassa N, Razavi Bani H, Hadjiakhoondi A. Free radical scavenging and lipid peroxidation activity of Shahany black grape. Pak J Biol Sci 2008; 11:1-4.

16. Benzie IFF, Strain JJ. Ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: The FRAP assay. Anal Biochem 1996; 239:70-76.

17. Jafari S, Moradi A, Salaritabar A, Hadjiakhoondi A, Khanavi M. Determination of total phenolic and flavonoid contents of Leonurus cardiaca L. in compare with antioxidant activity. Res J Biol Sci 2010; 5:484-487.

18. Noghogne LR, Gatsing1 D, Fotso, Kodjio N Sokoudjou JB, Kuiate JR. In vitro antisalmonellal and antioxidant properties of Mangifera indica L. stem bark crude extracts and fractions. Br J Pharm Res 2015; 5:29-41.

19. Plattner PLA, Magyar G. Zur Kenntnis der Sesquiterpene. Abbau des Dihydroguajols mit Chromsäure. Bereitung des 1,4,7-Trimethyl-azulens. Helv chim Acta 1942; 25:581-589.

20. Beadle GW, Brauns FE, Deulofeu V, Doudoroff M, Fox DL, Geiger E, et al.  Progress in the Chemistry of Organic Natural Products. Springer-Verlag, Vienna Austria: 1948.

21. Coruh N, Sagdioglu Celep AG, Ozgokce F. Antioxidant properties of Prangos ferulacea (L.) Lindl., Chaerophyllum macropodum Boiss. and Heracleum persicum Desf. from Apiaceae family used as food in eastern Anatolia and their inhibitory effects on glutathione-s-transferase. Food Chem 2007; 100:1237-1242.

22. Plazonic A, Mornar A, Males Z, Kujundzic N.  Phenolic content and antioxidant activities of Burr Parsley (Caucalis platycarpos L.). Molecules 2013; 18:8666-8681.

23. Saeed N, Khan MR, Shabbir M. Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L. BMC Complement Alt Med  2012; 12:221-233.

24. Cadiz-Gurrea M, Fernandez-Arroyo S, Joven J, Segura-Carretero A. Comprehensive characterization by UHPLC-ESI-Q-TOF-MS from an Eryngium bourgatii extract and their antioxidant and anti-inflammatory activities. Food Res Int 2013; 50:197-204.

25. Surveswaran S, Cai YZ, Corke H, Sun M. Systematic evaluation of natural phenolic antioxidants from 133 Indian medicinal plants. Food Chem 2007; 102:938-953.

26. Rebey IB, Zakhama N, Karoui IJ, Marzouk B. Polyphenol composition and antioxidant activity of Cumin (Cuminum Cyminum L.) seed extract under drought. J Food Sci 2012; 77:734-739.

27. Maulidiani, Abas F, Khatib A, Shaari K, Lajis NH. Chemical characterization and antioxidant activity of three medicinal Apiaceae species. Ind Crops Prod  2014; 55:238-247.