Iranian Journal of Basic Medical Sciences

Volume & Issue: Volume 29, Issue 6, June 2026, Pages 812-978

Number of Articles: 15

Review Article

Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey

Pages 812-822

10.22038/ijbms.2026.89795.19366

Dilpreet Singh, Satvir Singh, Nitin Tandon, Akshay Thakur, Neena Bedi

AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery

Pages 823-843

10.22038/ijbms.2026.90248.19456

Anmar Ghanim Taki, Abdulkareem Shareef, Vimal Arora, Rami Oweis, S. Renuka Jyothi, Udaybir Singh, Samir Sahoo, Ashish Singh Chauhan, Guzal Klebleeva, Hayder Naji Sameer, Ahmed Yaseen, Zainab H. Athab, Mohaned Adil

Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis

Pages 844-869

10.22038/ijbms.2026.88184.19047

Nimra Aziz, Ghulam Hussain, Qammar Abbas

Original Article

Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma

Pages 870-882

10.22038/ijbms.2026.88283.19066

Ting Wu, Yongshu Li, Zixian Wang, Bin Guo

Mechanistic insights into the protective effects of vitamin E against olanzapine-induced testicular toxicity: The role of microRNAs in oxidative stress and apoptosis

Pages 883-892

10.22038/ijbms.2026.91101.19649

Afraa Habeeb Qayssar, Ali Louei Monfared

Effects of glucocorticoid on cardiac chronotropic responsiveness in cirrhotic rats: A possible role for dopamine receptors

Pages 893-900

10.22038/ijbms.2026.91247.19739

Mohadese Shokrian Zeini, Maryam Shokrian Zeini, Qamar Niaz, Seyed Soheil Saeedi Saravi, Ahmad-Reza Dehpour, Farahnaz Jazaeri

Hepatoprotective effect of hUC-MSC secretome in LPS-induced HepG2 cells

Pages 901-908

10.22038/ijbms.2026.93115.20079

Wahyu Widowati, Philips Onggowidjaja, Massoud Vosough, Dwi Nur Triharsiwi, Anindita Putri Distya, Lisna Wahyu Nurani, Ismia Rahmawati, Any Aryani, Didik Priyandoko, Rizal Azis, Dhanar Septyawan Hadiprasetyo, Priyatharsini Rajendran, Kasim Sakran Abass, Safira Dinda Rifana

Combined effects of EGCG and retinol on viability and apoptosis-related gene expression in Caco-2 and HCT-116 colon cancer cells

Pages 909-914

10.22038/ijbms.2026.92570.19990

Saeedeh Ghorbani, Jamshidkhan Chamani, Monireh Movahedi, Zahra Kianmehr

CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease

Pages 915-926

10.22038/ijbms.2026.93063.20075

Ali Samareh, Mohammad Hadi Nematollahi, Hossein Pourghadamyari, Sanaz Rastegar, Hosseinali Ebrahimi, Morteza Hadizadeh, Hongsheng Wang, Lijun Tao, Hosseinali Sasan, Gholamreza Asadikaram

Huanglian Jiedu decoction ameliorates Alzheimer’s disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes

Pages 927-934

10.22038/ijbms.2026.91869.19827

Yong Yuan, Zhonghua Li, Ruifang Wang, Huandong Zhao, Junying Song

LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of immune checkpoint proteins in HCC with python analysis

Pages 935-941

10.22038/ijbms.2026.91840.19829

Masoud khodarahmi, Danial Amiri Manjili, Foroozan Yarahmadi, Tahere Mokhtari, Adib Dashtizadeh, Helia Rajabi Dezfooli, Khaterehsadat Monirvaghefi, Hossein Gharedaghi, Sina Dolatshahi, Zahra Hasanabadi, Farzaneh Moammer, Mahya Mobinikhaledi, Aida Yavari Kondori, Zahra Farajpour, Pardis Kondori Varnosfaderani, Zahra Hashemi, Mohammad Amin Mahdizadeh, Qumars Behfar, Siamak Sandoghchian Shotorbani, Nasibeh Sargazi Moghaddam

Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/Caspase-3, and TLR4/NF-κB axis activatione

Pages 942-951

10.22038/ijbms.2026.89049.19222

Tuba Karaarslan, Betul Apaydin Yildirim, Fatih Yildirim, Omercan Alat

Involvement of SIRT3 downstream targets ANT1, VDAC, CYPD, and Drp1 in a rat model of hepatic encephalopathy: Therapeutic role of thymoquinone

Pages 952-960

10.22038/ijbms.2026.93478.20159

Somayeh Hajipour, Mohammad Amin Dehghani, Alireza Sarkaki, Masoud Mahdavinia, Seyedeh Parisa Navabi

STAT3 ablation in keratinocytes ameliorates allergic contact dermatitis in DNCB-induced mice model

Pages 961-970

10.22038/ijbms.2026.94064.20274

Lu Chen, Cai Zhang, Limin Li, Huachun Wang, Wenchao Yao, Lei Xing, Jingyuan Gao, Zhengxiao Li, Faming Tian

In vivo assessment of imoxide and diluted vitamin C’s inhibitory effects on cervical cancer in mice

Pages 971-978

10.22038/ijbms.2026.93220.20105

Toktam Dehghani, Seyed Mousalreza Hosseini, Janbibi Dorazehi, Seyedeh Elnaz Nazari, Bahram Memar, Mojtaba Meshkat, Hoorieh Soleimanjahi, Omid Rajabi, Saeid Zibaee, Majid Khazaei, Zahra Meshkat