1. Amaral LM, Cornelius DC, Harmon A, Moseley J, Martin JN Jr, LaMarca B. 17-hydroxyprogesterone caproate significantly improves clinical characteristics of PE in the reduced uterine perfusion pressure rat model. Hypertension 2015; 65: 225-231.
2. Melchiorre K, Sharma R, Thilaganathan B. Cardiovascular implications in preeclampsia: An overview. Circulation 2014; 130: 703-714.
3. Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J, Gülmezoglu AM, Temmerman M, Alkema L. Global causes of maternal death: A WHO systematic analysis. Lancet Glob Health 2014; 2: e323-333.
4. Redman CW, Sacks GP, Sargent IL. Preeclampsia: An excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999; 180: 499-506.
5. Damsky CH, Librach C, Lim KH, Fitzgerald ML, McMaster MT, Janatpour M, et al. Integrin switching regulates normal trophoblast invasion. Development 1994; 120: 3657-3666.
6. Kliman HJ, Nestler JE, Sermasi E, Sanger JM, Strauss JF 3rd. Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology 1986; 118: 1567-1582.
7. Kohli S, Ranjan S, Hoffmann J, Kashif M, Daniel EA, Al-Dabet MM et al. Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts. Blood 2016; 128: 2153-2164.
8. Noris M, Perico N, Remuzzi G. Mechanisms of disease: Pre-eclampsia. Nat Clin Pract Nephrol 2005; 1: 98-114.
9. Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science 2005; 308: 1592-1594.
10. Svinarich DM, Bitonti OM, Romero R, Gonik B. Induction and posttranslational expression of cytokines in a first-trimester trophoblast cell line by lipopolysaccharide. Am J Obstet Gynecol 1996; 175: 970-973.
11. Zaga-Clavellina V, Garcia-Lopez G, Flores-Herrera H, Espejel-Nuñez A, Flores-Pliego A, Soriano-Becerril et al. In vitro secretion profiles of interleukin (IL)-1beta, IL-6, IL-8, IL-10, and TNF alpha after selective infection with Escherichia coli in human fetal membranes. Reprod Biol Endocrinol 2007; 5: 1-7.
12. Dowling O, Chatterjee PK, Gupta M, Tam Tam HB, Xue X, Lewis D et al. Magnesium sulfate reduces bacterial LPS-induced inflammation at the maternal-fetal interface. Placenta 2012; 33: 392-398.
13. Stacpoole PW. The pharmacology of dichloroacetate. Metabolism 1989; 38: 1124-1144.
14. Michelakis ED, Sutendra G, Dromparis P, Webster L, Haromy A, Niven E et al. Metabolic modulation of glioblastoma with dichloroacetate. Sci Transl Med 2010; 2: 31ra34.
15. Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M et al. HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun 2016; 7: 1-10.
16. Bian L, Josefsson E, Jonsson IM, Verdrengh M, Ohlsson C, Bokarewa M et al. Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice. Arthritis Res Ther 2009; 11: 1-10.
17. Horne AW, Ahmad SF, Carter R, Simitsidellis I, Greaves E, Hogg C et al. Repurposing dichloroacetate for the treatment of women with endometriosis. Proc Natl Acad Sci U S A 2019; 116: 25389-25391.
18. Shakhov AN, Collart MA, Vassalli P, Nedospasov SA, Jongeneel CV. Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J Exp Med 1990; 171: 35-47.
19. Landoni VI, Schierloh P, de Campos Nebel M, Fernández GC, Calatayud C, Lapponi MJ et al. Shiga toxin 1 induces on lipopolysaccharide-treated astrocytes the release of tumor necrosis factor-alpha that alter brain-like endothelium integrity. PLoS Pathog 2012; 8: e1002632.
20. Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282: 2085-2088.
21. Yang X, Haghiac M, Glazebrook P, Minium J, Catalano PM, Hauguel-de Mouzon S. Saturated fatty acids enhance TLR4 immune pathways in human trophoblasts. Hum Reprod. 2015; 30: 2152-2159.
22. Cramer M, Nagy I, Murphy BJ, Gassmann M, Hottiger MO, Georgiev O et al. NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biol Chem 2005; 386: 865-872.
23. Logothetou-Rella H, Kotoulas IG, Nesland JM, Kipiotis D, Abazis D. Early human trophoblast cell cultures. A morphological and immunocytochemical study. Histol Histopathol 1989; 4: 367-374.
24. Chen YY, Xiao L, Sun GQ, Li M, Yang HL, Ming ZY et al. TMBIM4 deficiency facilitates NLRP3 inflammasome activation-induced pyroptosis of trophoblasts: A potential pathogenesis of preeclampsia. Biology (Basel) 2023; 12: 1-17.
25. Liang CC, Park AY, Guan JL. In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2007; 2: 329-333.
26. Jonkman JEN, Cathcart JA, Xu F, Bartolini ME, Amon JE, Stevens KM et al. An introduction to the wound healing assay using live-cell microscopy. Cell Adh Migr 2014; 8: 440-451.
27. Justus CR, Leffler N, Ruiz-Echevarria M, Yang LV. In vitro cell migration and invasion assays. J Vis Exp 2014; 88: 1-8.
28. Abbas Y, Turco MY, Burton GJ, Moffett A. Investigation of human trophoblast invasion in vitro. Hum Reprod Update 2020; 26: 501-513.
29. Peng C, Yang LJ, Zhang C, Jiang Y, Shang LLWX, He JB et al. Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice. Acta Pharmacol Sin 2023; 44: 44-57.
30. Otsuka K, Terasaki F, Ikemoto M, Fujita SC, Tsukada B, Katashima T et al. Suppression of inflammation in rat autoimmune myocarditis by S100A8/A9 through modulation of the proinflammatory cytokine network. Eur J Heart Fail 2009; 11: 229-237.
31. Liu KH, Zhang BL, Yang BS, Shi WT, Li YF, Wang Y et al. Rhizobiales-specific RirA represses a naturally “synthetic” foreign siderophore gene cluster to maintain sinorhizobium-legume mutualism. mBio 2021; 13: e0290021.
32. Qi D, Lu JY, Fu ZY, Lv SS, Hou LL. Psoralen promotes proliferation, migration, and invasion of human extravillous trophoblast derived HTR-8/Svneo cells in vitro by NF-κB pathway. Front Pharmacol 2022; 13: 1-10.
33. Janovec V, Ryabchenko B, Škarková A, Pokorná K, Rösel D, Brábek J et al. TLR4-mediated recognition of mouse polyomavirus promotes cancer-associated fibroblast-like phenotype and cell invasiveness. Cancers (Basel) 2021; 13: 1-16.
34. Oh KK, Adnan M, Cho DH. Drug investigation to dampen the comorbidity of rheumatoid arthritis and osteoporosis via molecular docking test. Curr Issues Mol Biol 2022; 44: 1046-1061.
35. Zhang YY, Zhang Y, Yao YB, Lei XL, Qian ZJ. Butyrolactone-I from coral-derived fungus aspergillus terreus attenuates neuro-inflammatory response via suppression of NF-κB pathway in BV-2 cells. Mar Drugs 2018; 16: 1-13.
36. Du M, Yuan L, Tan X, Huang D, Wang X, Zheng Z et al. The LPS-inducible lncRNA Mirt2 is a negative regulator of inflammation. Nat Commun 2017; 8: 1-18.
37. Gao H, Sun W, Zhao J, Wu X, Lu JJ, Chen X et al. Tanshinones and diethyl blechnics with anti-inflammatory and anti-cancer activities from Salvia miltiorrhiza Bunge (Danshen). Sci Rep 2016; 26: 1-13.
38. Askie LM, Duley L, Henderson-Smart DJ, Stewart LA. Antiplatelet agents for prevention of pre-eclampsia: A meta-analysis of individual patient data. Lancet 2007; 369: 1791-1798.
39. Davies JE, Pollheimer J, Yong HEJ, Kokkinos MI, Kalionis B, Knöfler M et al. Epithelial-mesenchymal transition during extravillous trophoblast differentiation. Cell Adh Migr 2016; 10: 310-321.
40. Msheik H, Azar J, Sabeh ME, Abou-Kheir W, Daoud G. HTR-8/SVneo: A model for epithelial to mesenchymal transition in the human placenta. Placenta 2020; 90: 90-97.
41. Abou-Kheir W, Barrak J, Hadadeh O, Daoud G. HTR-8/SVneo cell line contains a mixed population of cells. Placenta 2017; 50: 1-7.
42. Granger JP. Inflammatory cytokines, vascular function, and hypertension. Am J Physiol Regul Integr Comp Physiol 2004; 286: R989-R990.
43. Takashima K, Matsunaga N, Yoshimatsu M, Hazeki K, Kaisho T, Uekata M et al. Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model. Br J Pharmacol 2009; 157: 1250-1262.
44. Liu Z, Chen L, Yu P, Zhang Y, Fang B, Wu C et al. Discovery of 3-(Indol-5-yl)-indazole derivatives as novel myeloid differentiation protein 2/Toll-like receptor 4 antagonists for treatment of acute lung injury. J Med Chem 2019; 62: 5453-5469.
45. Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K et al. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 1999; 189: 1777-1782.
46. Vaughan JE, Walsh SW. Activation of NF-κB in placentas of women with preeclampsia. Hypertens Pregnancy 2012; 31: 243-251.