Hsu PC, Guo YL. Antioxidant nutrients and lead toxicity. Toxicol
ogy 2002; 30;80:33-44.
2. Xu J, Ji LD, Xu LH. Lead-induced apoptosis in PC 12 cells: involvement of p53, Bcl-2 family and caspase-3. Toxicol Lett 2006; 166:160-167.
3. Patrick L. Lead toxicity, a review of the literature. Part 1: Exposure, evaluation, and treatment. Altern Med Rev 2006; 11:2-22.
4. Woolf AD, Goldman R, Bellinger DC. Update on the clinical management of childhood lead poisoning. Pediatr Clin North Am 2007; 54:271-294.
5. Alfano DP, Petit TL. Behavioral effects of postnatal lead exposure: possible relationship to hippocampal dysfunction. Behav Neural
164
Biol 1981; 32:319-333.
6. Altmann L, Weinsberg F, Sveinsson K, Lilienthal H, Wiegand H, Winneke G. Impairment of long-term potentiation and learning following chronic lead exposure. Toxicol Lett 1993; 66:105-112.
7. Dey PM, Burger J, Gochfeld M, Reuhl KR. Toxicology. Developmental lead exposure disturbs expression of synaptic neural cell adhesion molecules in herring gull brains 2005; 146:137-147.
8. Finkelstein Y, Markowitz ME, Rosen JF. Low-level lead-induced neurotoxicity in children: an update on central nervous system effects. Brain Res Brain Res Rev 1998; 27:168-176.
9. Al-Saleh I, Al-Enazi S, Shinwari N. Assessment of lead in cosmetic products. Regul Toxicol Pharmacol 2009; 54: 105–113
10. Tavakoli-Nezhad M, Barron AJ, Pitts DK. Postnatal inorganic lead exposure decreases the number of spontaneously active midbrain dopamine neurons in the rat. Neurotoxicology 2001; 22:259-269.
11. Liu J, Han D, Li Y, Zheng L, Gu C, Piao Z,
et al.
Lead affects apoptosis and related gene XIAP and Smac expression in the hippocampus of developing rats. Neurochem Res 2010; 35:473-479.
12. Han JM, Chang BJ, Li TZ, Choe NH, Quan FS, Jang BJ,
et al. Protective effects of ascorbic acid against lead-induced apoptotic neurodegeneration in the developing rat hippocampus in vivo
. Brain Res 2007; 14;1185:68-74.
13. Zsombok A, Tóth Z, Gallyas F. Basophilia, acidophilia and argyrophilia of "dark" (compacted) neurons during their formation, recovery or death in an otherwise undamaged environment. J Neurosci Methods 2005; 15;142:145-152.
14. Krysko DV, Vanden Berghe T, D’Herde K, Vandenabeele P. Apoptosis and necrosis: detection, discrimination and phagocytosis. Methods 2008; 44:205-221.
15. Kherani ZS, Auer RN. Pharmacologic analysis of the mechanism of dark neuron production in cerebral cortex. Acta Neuropathol 2008; 116:447-452.
16. Graeber MB, Blakemore WF, Kreutzberg GW. Cellular pathology of the central nervous system. In: Graham DI, Lantos PL. editors. Greenfield’s neuropathology, vol 1. Arnold: London; 2002. p 126.
17. Rajanna B, Rajanna S, Hall E, Yallapragada PR.
In vitro
metal inhibition of N-methyl-D-aspartate specific glutamate receptor binding in neonatal and adult rat brain. Drug Chem Toxicol 1997; 20:21-29.
18. Adhikari N, Sinha N, Narayan R, Saxena DK. Lead-induced cell death in testes of young rats. J Appl Toxicol 2001; 21:275-277.
19. Shabani A, Rabbani A. Lead nitrate induced apoptosis in alveolar macrophages from rat lung. Toxicology 2000; 149:109-114.
20. Lutsenko EA, Cárcamo JM, Golde DW. Vitamin C prevents DNA mutation induced by oxidative stress. J Biol Chem 2002; 277:16895-16899.
21. Senapati SK, Dey S, Dwivedi SK, Defect of garlic (Allium sativum L.) extract on tissue lead level in rats. J Ethnopharmacol 2000; 76:229-232.
22. Chen YH, Xu DX, Zhao L, Wang H, Wang JP, Wei W. Ascorbic acid protects against lipopolysaccharide-induced intra-uterine fetal death and intra-uterine growth retardation in mice. Toxicology 2006; 217:39-45.
23. Simon JA, Hudes ES. Relationship of ascorbic acid to blood lead levels. JAMA 1999; 281:2289-2293.
24. Sharifi AM, Mousavi SH, Jorjani M. Effect of chronic lead exposure on pro-apoptotic Bax and anti-apoptotic Bcl-2 protein expression in rat hippocampus
in vivo
. Cell Mol Neurobiol 2010; 30:769-774.
25. Bennet C, Bettaiya R, Rajanna S, Baker L, Yallapragada PR, Brice JJ,
et al.
Region specific increase in the antioxidant enzymes and lipid peroxidation products in the brain of rats exposed to lead. Free Radic Res 2007; 41:267-273.
26. Vissers MC, Lee WG, Hampton MB. Regulation of apoptosis by vitamin C. Specific protection of the apoptotic machinery against exposure to chlorinated oxidants. J Biol Chem 2001; 276:46835- 4640.
27. Massadeh AM, Al-Safi SA, Momani IF, Alomary AA, Jaradat QM, AlKofahi AS. Garlic (
Allium sativum
L.) as a potential antidote for cadmium and lead intoxication: cadmium and lead distribution and analysis in different mice organs. Biol Trace Elem Res 2007; 120:227-234.
28. Mabrouk MA, Nnawodu FI, Tanko Y, Dawud F, Mohammed A. Effect of Aqueous Garlic (Ag) Extract on Aspirin Induced Gastric Mucosal Lesion in Albino Wistar Rat. Curr Res J Biol Sci 2009; 1:15- 19.
29. Iciek M, Kwiecien I, Włodek L. Biological properties of garlic and garlic-derived organosulfur compounds. Environ Mol Mutagen 2009; 50:247-265.
30. Alnaqeeb MA, Thomson M, Bordia T, Ali M. Histopathological effects of garlic on liver and lung of rats. Toxicol Lett 1996; 85:157- 164.
31. Shahsavani D, Baghshani H, Alishahi E. Efficacy of allicin in decreasing lead (Pb) accumulation in selected tissues of lead-exposed common carp (Cyprinus carpio). Biol Trace Elem Res 2011; 142:572-580.
32. Ebrahimzadeh Bideskan AR, Nikravesh MR, Hassanzadeh Taheri MM, Fazel AR. Lectinhistochemical study of vasculogenesis during rat pituitary morphogenesis. Iran J Basic Med Sic 2011; 14:161- 169.
33. Rajabzadeh AA, Ebrahimzadeh Bideskan AR, Haghir H, Fazel AR. Morphometrical study of PSA-NCAM positive cells in rat pups hippocampus following induction of seizure during pregnancy. Iran Biomed J 2011; 15:157-163.
34. Hsu PC, Liu MY, Hsu CC, Chen LY, Guo YL. Effects of vitamin E and/ or C on reactive oxygen species-related lead toxicity in the rat sperm. Toxicology 1998;128:169-179.
35. Baluchnejad mojarad T, Roghani M, Homayounfar H, Hosseini M. Beneficial effect of aqueous garlic extract on the vascular reactivity of streptozotocin diabetic rats. . J Ethnopharmacol 2003; 85: 139-144.
36. Hosseini M, Shafiee SM, Baluchnejad mojarad T. Garlic extract reduces serum angiotensin converting enzyme (ACE) activity in nondiabetic and streptozotocin-diabetic rats. Pathophysiology 2007; 14:109–112.
37. Onunkwor B, Dosumu O, Odukoya OO, Arowolo T, Ademuyiwa O. Biomarkers of lead exposure in petrol station attendants and auto-mechanics in Abeokuta, Nigeria: effect of 2-week ascorbic acid supplementation. Environ Toxicol Pharmacol 2004; 17:169- 176.
38. De Roos, FJ. Smelters and metal reclaimers. In: Greenberg MI, Hamilton RJ, Phillips SD, McCluskey GJ. editors. Occupational, Industrial, and Environmental Toxicology.2nd ed. Philadelphia: Mosby; 2003.p.388–397.
39. Bolin CM, Basha R, Cox D, Zawia NH, Maloney B, Lahiri DK,
et al.
Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain. FASEB J 2006; 20:788-790.
40. Handlogten ME, Shiraishi N, Awata H, Huang C, Miller RT. Extracellular Ca(2+)-sensing receptor is a promiscuous divalent cation sensor that responds to lead. Am J Physiol Renal Physiol 2000; 279:F1083-1091.
41. Danadevi K, Rozati R, Saleha Banu B, Hanumanth Rao P, Grover P. DNA damage in workers exposed to lead using comet assay. Toxicology 2003; 187:183-193.
42. Garza A, Vega R, Soto E. Cellular mechanisms of lead neurotoxicity. Med Sci Monit 2006; 12:57-65.
43. Gurer H, Ercal N. Can antioxidants be beneficial in the treatment of lead poisoning? Free Radic Biol Med 2000; 29:927-945.
44. Dawson EB, Evans DR, Haris WA, Teter MC, McGanity WJ. The effect of ascorbic acid supplementation on the blood lead levels of smokers. J Am Coll Nutr 1999; 18:166-170.
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