1. Sierra DA, Gilbert DJ, Householder D, Grishin NV, Yu K, Ukidwe P, et al. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics 2002; 79:177-185.
2. Xie GX, Palmer PP. How regulators of G protein signaling achieve selective regulation. J Mol Biol 2007; 366:349-365.
3. Benjamin LE, Golijanin D, Itin A, Pode D, Keshet E. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 1999; 103:159-165.
4. Zhou J, Moroi K, Nishiyama M, Usui H, Seki N, Ishida J, et al. Characterization of RGS5 in regulation of G protein-coupled receptor signaling. Life Sci 2001; 68:1457-1469.
5. Berman DM, Gilman AG. Mammalian RGS proteins: barbarians at the gate. J Biol Chem 1998; 273:1269-1272.
6. Anger T, Klintworth N, Stumpf C, Daniel WG, Mende U, Garlichs CD. RGS protein specificity towards Gq- and Gi/o-mediated ERK 1/2 and Akt activation, in vitro. J Biochem Mol Biol 2007; 40:899-910.
7. Anger T, Grebe N, Osinski D, Stelzer N, Carson W, Daniel WG, et al. Role of endogenous RGS proteins on endothelial ERK 1/2 activation. Exp Mol Pathol 2008; 85:165-173.
8. Wang Q, Liu M, Mullah B, Siderovski DP, Neubig RR. Receptor-selective effects of endogenous RGS3 and RGS5 to regulate mitogen-activated protein kinase activation in rat vascular smooth muscle cells. J Biol Chem 2002; 277:24949-24958.
9. Sato M, Moroi K, Nishiyama M, Zhou J, Usui H, Kasuya Y, et al. Characterization of a novel C. elegans RGS protein with a C2 domain: evidence for direct association between C2 domain and Galphaq subunit. Life Sci 2003; 73:917-932.
10. Sjogren B, Neubig RR. Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling. Mol Pharmacol 2010; 78:550-557.
11. Mitchell TS, Bradley J, Robinson GS, Shima DT, Ng YS. RGS5 expression is a quantitative measure of pericyte coverage of blood vessels. Angiogenesis 2008; 11:141-151.
12. Li H, He C, Feng J, Zhang Y, Tang Q, Bian Z, et al. Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload. Proc Natl Acad Sci USA 2010; 107:13818-13823.
13. Holobotovskyy V, Manzur M, Tare M, Burchell J, Bolitho E, Viola H, et al. Regulator of G-protein signaling 5 controls blood pressure homeostasis and vessel wall remodeling. Circ Res 2013; 112:781-791.
14. Jin Y, An X, Ye Z, Cully B, Wu J, Li J. RGS5, a hypoxia-inducible apoptotic stimulator in endothelial cells. J Biol Chem 2009; 284:23436-23443.
15. Silini A, Ghilardi C, Figini S, Sangalli F, Fruscio R, Dahse R, et al. Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment. Cell Mol Life Sci 2012; 69:1167-1178.
16. Huang G, Song H, Wang R, Han X, Chen L. The relationship between RGS5 expression and cancer differentiation and metastasis in non-small cell lung cancer. J Surg Oncol 2012; 105:420-424.
17. Boss CN, Grunebach F, Brauer K, Hantschel M, Mirakaj V, Weinschenk T, et al. Identification and characterization of T-cell epitopes deduced from RGS5, a novel broadly expressed tumor antigen. Clin Cancer Res 2007; 13:3347-3355.
18. Yao M, Huang Y, Shioi K, Hattori K, Murakami T, Sano F, et al. A three-gene expression signature model to predict clinical outcome of clear cell renal carcinoma. Int J Cancer 2008; 123:1126-1132.
19. Wang JH, Huang WS, Hu CR, Guan XX, Zhou HB, Chen LB. Relationship between RGS5 expression and differentiation and angiogenesis of gastric carcinoma. World J Gastroenterol 2010; 16:5642-5646.
20. Liang Y, Li C, Burke J, Protzman C, Krauss A-H, Nieves A, et al. Upregulation of regulator of G protein signaling 5 (RGS5) in the iris-ciliary body of chronic ocular hypertensive primates. Invest Ophthalmol Vis Sci 2002; 43:3387.
21. Liang Y, Li C, Guzman VM, Chang WW, Evinger AJ, 3rd, Sao D, et al. Identification of a novel alternative splicing variant of RGS5 mRNA in human ocular tissues. FEBS J 2005; 272:791-799.
22. Gasiorowski JZ, Russell P. Biological properties of trabecular meshwork cells. Exp Eye Res 2009; 88:671-675.
23. Sommer A. Intraocular pressure and glaucoma. Am J Ophthalmol 1989; 107:186-188.
24. Paylakhi SH, Yazdani S, April C, Fan JB, Moazzeni H, Ronaghi M, et al. Non-housekeeping genes expressed in human trabecular meshwork cell cultures. Mol Vis 2012; 18:241-254.
25. Zhao X, Pearson KE, Stephan DA, Russell P. Effects of prostaglandin analogues on human ciliary muscle and trabecular meshwork cells. Invest Ophthalmol Vis Sci 2003; 44:1945-1952.
26. Zhao X, Ramsey KE, Stephan DA, Russell P. Gene and protein expression changes in human trabecular meshwork cells treated with transforming growth factor-beta. Invest Ophthalmol Vis Sci 2004; 45:4023-4034.
27. Paylakhi SH, Fan JB, Mehrabian M, Sadeghizadeh M, Yazdani S, Katanforoush A, et al. Effect of PITX2 knockdown on transcriptome of primary human trabecular meshwork cell cultures. Mol Vis 2011; 17:1209-1221.
28. Gonzalez P, Epstein DL, Borras T. Characterization of gene expression in human trabecular meshwork using single-pass sequencing of 1060 clones. Invest Ophthalmol Vis Sci 2000; 41:3678-3693.
29. Tomarev SI, Wistow G, Raymond V, Dubois S, Malyukova I. Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis. Invest Ophthalmol Vis Sci 2003; 44:2588-2596.
30. Liu Y, Munro D, Layfield D, Dellinger A, Walter J, Peterson K, et al. Serial analysis of gene expression (SAGE) in normal human trabecular meshwork. Mol Vis 2011; 17:885-893.
31. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116:281-297.
32. Ambros V. The functions of animal microRNAs. Nature 2004; 431:350-355.
33. Ouellet DL, Perron MP, Gobeil LA, Plante P, Provost P. MicroRNAs in gene regulation: when the smallest governs it all. J Biomed Biotechnol 2006; 2006:69616.
34. Hughes AE, Bradley DT, Campbell M, Lechner J, Dash DP, Simpson DA, et al. Mutation altering the miR-184 seed region causes familial keratoconus with cataract. Am J Hum Genet 2011; 89:628-633.
35. Liu N, Landreh M, Cao K, Abe M, Hendriks GJ, Kennerdell JR, et al. The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila. Nature 2012; 482:519-523.
36. Zhang N, Li X, Wu CW, Dong Y, Cai M, Mok MT, et al. microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis. Oncogene 2013; 32:5078-5088.
37. Baek D, Villen J, Shin C, Camargo FD, Gygi SP, Bartel DP. The impact of microRNAs on protein output. Nature 2008; 455:64-71.
38. Nilsen TW. Mechanisms of microRNA-mediated gene regulation in animal cells. Trends Genet 2007; 23:243-249.
39. Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N. Widespread changes in protein synthesis induced by microRNAs. Nature 2008; 455:58-63.
40. Friedman RC, Farh KK, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009; 19:92-105.
41. Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120:15-20.
42. Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 2003; 115:787-798.
43. Ritchie W, Rasko JE, Flamant S. MicroRNA target prediction and validation. Adv Exp Med Biol 2013; 774:39-53.
44. Witkos TM, Koscianska E, Krzyzosiak WJ. Practical Aspects of microRNA Target Prediction. Curr Mol Med 2011; 11:93-109.
45. Karali M, Peluso I, Marigo V, Banfi S. Identification and characterization of microRNAs expressed in the mouse eye. Invest Ophthalmol Vis Sci 2007; 48:509-515.
46. Conte I, Carrella S, Avellino R, Karali M, Marco-Ferreres R, Bovolenta P, et al. miR-204 is required for lens and retinal development via Meis2 targeting. Proc Natl Acad Sci USA 2010; 107:15491-15496.
47. Dunmire JJ, Lagouros E, Bouhenni RA, Jones M, Edward DP. MicroRNA in aqueous humor from patients with cataract. Exp Eye Res 2013; 108:68-71.
48. Hoffmann A, Huang Y, Suetsugu-Maki R, Ringelberg CS, Tomlinson CR, Del Rio-Tsonis K, et al. Implication of the miR-184 and miR-204 competitive RNA network in control of mouse secondary cataract. Mol Med 2012; 18:528-538.
49. Li G, Luna C, Qiu J, Epstein DL, Gonzalez P. Role of miR-204 in the regulation of apoptosis, endoplasmic reticulum stress response, and inflammation in human trabecular meshwork cells. Invest Ophthalmol Vis Sci 2011; 52:2999-3007.
50. Paylakhi SH, Moazzeni H, Yazdani S, Rassouli P, Arefian E, Jaberi E, et al. FOXC1 in human trabecular meshwork cells is involved in regulatory pathway that includes miR-204, MEIS2, and ITGbeta1. Exp Eye Res 2013; 111:112-121.
51. Dweep H, Sticht C, Pandey P, Gretz N. miRWalk--database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform 2011; 44:839-847.
52. Li G, Luna C, Qiu J, Epstein DL, Gonzalez P. Modulation of inflammatory markers by miR-146a during replicative senescence in trabecular meshwork cells. Invest Ophthalmol Vis Sci 2010; 51:2976-2985.
53. Luna C, Li G, Qiu J, Epstein DL, Gonzalez P. MicroRNA-24 regulates the processing of latent TGFbeta1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURIN. J Cell Physiol 2011; 226:1407-1414.
54. Gessert S, Bugner V, Tecza A, Pinker M, Kuhl M. FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Dev Biol 2010; 341:222-235.
55. Xu S, Witmer PD, Lumayag S, Kovacs B, Valle D.
MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster. J Biol Chem 2007; 282:25053-25066.