Frequency and the Type of Chromosomal Abnormalities in Patients  with Primary Amenorrhea in Northeast of Iran

Mohajertehran, Farnaz; Ghodsi, Kazem; Hafizi, Leili; Rezaee, Ameneh

doi:10.22038/ijbms.2013.724

Frequency and the Type of Chromosomal Abnormalities in Patients with Primary Amenorrhea in Northeast of Iran

Document Type : Original Article

Authors

¹ Department of Genetics, Ghaem Hospital, Mashhad University of Medical Sciences , Mashhad, Iran

² Departmen of Medical Genetics and Immunology and Allergy Immunology and stem cell Department, Ghaem Hospital, Mashhad University of Medical

³ Obstetrics & Gynecology Department, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

⁴ Urgency Department, Imam Reza Hospital, Mashhad University of Medical Sciences , Mashhad, Iran Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran

10.22038/ijbms.2013.724

Keywords

Keywords: Chromosomal abnormalities Cytogenetic Study Iran Karyotyping Primary Amenorrhea

References

Schorge JO, Schaffer JI, Halvorson LM, Hoffman BL, Bradshaw KD,

Cunningham FG. Amenorrhea. In: Schorge JO, Schaffer JI.editors. Williams Gynecology. New York, NY: McGraw Hill; 2008.p. 1112- 1128.

2. Speroff L, Glass RH, Kase NG. editors. Amenorrhea. In: Clinical Gynecologic Endocrinology and Infertility. 6th ed. USA: Lippincott Williams and Wilkins; 1999. p. 421-476.

3. Achermann J, Huges IA. Disorders of Sex Development. In: Kronenberg HM. Editor. Williams’s, Textbook of Endocrinology, 11th ed. Philadelphia: Saunders Elsevier; 2008.p. 811-822.

4. Rosa RF, Dibi R P, Picetti JS, Rosa RC, Zen PR, Graziadio C,

et al.

Amenorrhea and X chromosome abnormalities. Rev Bras Ginecol Obstet 2008; 30:511-517.

5. Zhao X, Shen GM, Feng Q, Sun XG, Luo Y. Cytogenetic studies of 131 patients with primary amenorrhea (including three novel abnormal karyotypes). Yi Chuan 2008; 30:996-1002.

6. Balkan M, Akbas H, Isi H

, Oral D, Turkyılmaz A, Kalkanli S, Simsek S, et al. Cytogenetic analysis of 4216 patients referred for suspected chromosomal abnormalities in Southeast Turkey. Genet Mol Res 2010; 9:1094-1103.

Wong MSF, Lam STS. Cytogenetic analysis of patients with primary amenorrhea and secondary amenorrhea in Hong Kong: retrospective study. Hong Kong Med J 2005; 11:267-272.

8. Joseph A, Thomas IM. Cytogenetic investigation in 150 cases with complaints of sterility or primary amenorrhea. Hum Genet 1982; 61:105-109.

9. Ten SK, Chin YM, Noor PJ, Hassan K. Cytogenetic studies in women with primary amenorrhea. Singapore Med J 1990; 31:355-359.

10. Temocin K, Vardar MA, Suleymanova D, Ozer E, Tanriverdi N, Demirhan O . Results of cytogenetic investigation in adolescent patients with primary or secondary amenorrhea. J Pediatr Adolesc Gynecol 1997; 10:86-88.

11. Roy AK, Banerjee D. Cytogenetic study of primary amenorrhoea. J Indian Med Assoc 1995; 93:291-292.

12. Niekerk WA. Chromosomes and the gynecologist. Am J Obstet Gynecol 1978; 130:862-875.

13. Safaei A, Vasei M, Ayatollahi H. Cytogenetic analysis of patients with primary amenorrhea in Southwest of Iran. Iran J Pathol 2010; 5:121-125.

14. Verma RS, Arvind B. Human chromosomes- principles and techniques. 2nd ed. New York: McGraw-Hill Inc; 1995.

15. Vijayalakshmi J, Koshy T, Kaur H. Cytogenetic analysis of patients with primary amenorrhea. Int J Hum Genet 2010; 10: 71-76.

16. Lakhal B, Laissue P, Braham R, Elghezal H, Saâd A, Fellous M,

et al.

BMP15 and premature ovarian failure: causal mutations, variants, polymorphisms? Clin Endocrinol (Oxf) 2009; 72:425–426.

17. Vasu VR, Chandra N, Santhiya ST. X;7 translocation in an Indian woman with hypergonadotropic amenorrhea—a case report. Genet Test Mol Biomarkers 2009; 13:533–536.

Cortés-Gutiérrez EI, Dávila-Rodríguez MI, Vargas- Villarreal J, Cerda-Flores RM. Prevalence of chromosomal aberrations in Mexican women with primary amenorrhoea. Reprod Biomed Online 2007; 15:463-467.

19. Kalavathi VN, Renjini Nambiar G, Chandra N, Jayashree S, Sugunashankari P, Meena J,

et al.

Chromosomal abnormalities in 979 cases of amenorrhea: a review. Int J Hum Genet 2010; 10:65–69.

20. Ramírez G, Herrera C, Durango N, Ramírez J. Cariotipo 45, X/46, X, r(X) en pacientes con diagnostic clínico de síndrome de Turner / 45, X/46, X, r (X) karyotype in patients with clinical diagnosis of Turner’s syndrome. Iatreia 2000; 13:161-166.

21. Kong H, Ge YS, Wu Q, Wu HN, Zhou DX, Shen YY. Molecular and cytogenetic study on 18 cases of amenorrhea: the use of fluorescence in situ hybridization and high resolution comparative genomic hybridization. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2007; 24:256-60.

22. Butnariu L, Covic M, Ivanov I, Bujoran C, Gramescu M, Vlad Gorduza E. Clinical and cytogenetic correlation in primary and secondary amenorrhea: retrospective study on 531 patients. Revista Român

ă de Medicină de Laborator 2011; 19:149-160.