Iranian Journal of Basic Medical Sciences

Keywords = Apoptosis

Gypenosides alleviates MCT-induced pulmonary arterial hypertension in rats by targeting oxidative stress, inflammation, and apoptosis

Articles in Press, Accepted Manuscript, Available Online from 30 April 2025

10.22038/ijbms.2025.82437.17822

Du Dan; Xiao-Wei Gong; Ya-Dong Yuan

Voluntary exercise alleviates ischemic brain injury in mice by modulating mitochondrial dysfunction

Volume 28, Issue 7, July 2025, Pages 846-851

10.22038/ijbms.2025.80783.17488

Beibei Li; Ye Zhou; Guifen Yang; Bo Li; Mingjin Zhu; Dan Lu; Senge Dai; Guoyuan Pan

Thymoquinone prevents valproic acid-induced hepatotoxicity via modulation of cytochrome P450, PPARs, and apoptotic pathways

Volume 28, Issue 7, July 2025, Pages 899-906

10.22038/ijbms.2025.85190.18407

Sebile Azirak; Sedat Bilgiç; Deniz Taştemir Korkmaz; İlkay Armağan; Mehmet Kaya Özer

Troxerutin alleviates hepatorenal toxicity induced by carbon tetrachloride in male mice

Volume 28, Issue 7, July 2025, Pages 955-961

10.22038/ijbms.2025.84752.18337

Elham Hakimizadeh; Ayat Kaeidi; Iman Fatemi; Ali Shamsizadeh; Jalal Hassanshahi

Azelaic acid reduces arsenic-induced toxicity and inflammation in the rat islets of langerhans

Volume 28, Issue 6, June 2025, Pages 784-789

10.22038/ijbms.2025.84651.18311

Sara Mostafalou; Fatemeh Moafi-Madani; Maryam Baeeri; Mahban Rahimifard; Hamed Haghi-Aminjan

Apigenin attenuates myocardial ischemia-reperfusion injury through miR-448/SIRT1 axis

Volume 28, Issue 5, May 2025, Pages 602-611

10.22038/ijbms.2025.80172.17365

Chenchen Tian; Bo Yu; Yibo Liu; Zhipeng Diao; Yue Wang; Jianmei Zhou

Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats

Volume 28, Issue 5, May 2025, Pages 612-619

10.22038/ijbms.2025.79750.17275

AhmadReza Aminian; Mohammad Taghi Khoshniat; Abolfazl Khajavirad; Maryam Mahmoudabady; Mohammad Hossein Rigi; Sara Hoseinian

Amantadine reduces sepsis-induced brain injury via NLRP3/caspase-1 inflammasome activation

Volume 28, Issue 5, May 2025, Pages 620-626

10.22038/ijbms.2025.81436.17626

Pinar Karabacak; Ahmet Bindal; Mustafa Soner Ozcan; Ilter Ilhan; Muhammet Yusuf Tepebası; Melih Arlıoglu; Rumeysa Taner; Halil Ascı

Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery

Volume 28, Issue 5, May 2025, Pages 627-637

10.22038/ijbms.2025.81837.17706

Ramin Abrishami; Ramtin Farhadi; Mehri Farhang Ranjbar; Seyed Hadi Aghili; Maryam Baeeri

Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway

Volume 28, Issue 4, April 2025, Pages 418-425

10.22038/ijbms.2025.82513.17836

Huan-Qi Zhang; Dao-Ming Zhang; Zhi-Zhen Huang; Jing Cheng; Chong Zhang; Neng-Ming Lin; Yang-Ling Li

Pre- and post-traumatic boric acid therapy prevents oxidative stress-mediated neuronal apoptosis in spinal cord injury

Volume 28, Issue 4, April 2025, Pages 444-450

10.22038/ijbms.2024.81531.17649

Turan Kandemir; İbrahim Söğüt; Zeki Serdar Ataizi; Betül Can; Ayşegül Oğlakçı İlhan; Dilek Burukoglu Donmez; Güngör Kanbak

Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats

Volume 28, Issue 4, April 2025, Pages 461-468

10.22038/ijbms.2025.79979.17326

Ozlem Ozmen; Melda Şahin; Senay Topsakal; Şerife Taşan; Uğur Şahi̇n

Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways

Volume 28, Issue 4, April 2025, Pages 507-515

10.22038/ijbms.2025.79735.17270

Hasan Şimşek; Nurhan Akaras; Cihan Gur; Sefa Kucukler; Mustafa Ileriturk; Fatih Mehmet Kandemir

Rosmarinic acid attenuated inflammation and apoptosis in folic acid-induced renal injury: Role of FoxO3/ NFκB pathway

Volume 28, Issue 3, March 2025, Pages 316-322

10.22038/ijbms.2024.80551.17436

Maryam Mottaghi; Fatemeh Heidari; Tahereh Komeili Movahhed; Akram Eidi; Azam Moslehi

COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway

Volume 28, Issue 3, March 2025, Pages 340-346

10.22038/ijbms.2024.80284.17378

Yuancai Zheng; Keqi Wang; Chenyu Wu; Yuying Qin; Yihan Sun; Xinyu Lu; Yupeng Xu; Gonghui Li

Cardiotoxicity caused by acrylamide in rats can be alleviated as a result of suppression of oxidative stress, endoplasmic reticulum stress, inflammation, and apoptosis by morin treatment

Volume 28, Issue 3, March 2025, Pages 376-384

10.22038/ijbms.2024.81490.17634

Fatma Cakmak; Sefa Kucukler; Cihan Gur; Mustafa Ileriturk; Murat Gul; Behcet Varisli

The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration

Volume 28, Issue 3, March 2025, Pages 393-400

10.22038/ijbms.2024.79218.17163

Jing Luan; Qi Wang; Wei Zheng; Yongjin He

Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway

Volume 28, Issue 2, February 2025, Pages 187-193

10.22038/ijbms.2024.80438.17412

Jingsong Wang; Qingyuan Zheng; Jun Jian; Xiuheng Liu; Zhiyuan Chen; Shanshan Wan; Lei Wang

Trans-sodium crocetinate ameliorates Parkinson-like disease caused by bisphenol A through inhibition of apoptosis and reduction of α-synuclein in rats

Volume 28, Issue 2, February 2025, Pages 254-263

10.22038/ijbms.2024.81157.17567

Majid Keshavarzi; Bibi Marjan Razavi; Hossein Hosseinzadeh

Effect of anemoside B4 on ameliorating cerebral ischemic/reperfusion injury

Volume 28, Issue 1, January 2025, Pages 49-55

10.22038/ijbms.2024.78569.16991

Fei Huizhi; Xiaohuan Huang

Lysyl oxidase-like 2 promotes the survival, migration, and ferroptosis of endometrial cancer cells by activating the phosphoinositide 3-kinase/protein kinase B pathway

Volume 28, Issue 1, January 2025, Pages 72-79

10.22038/ijbms.2024.79933.17317

Jiashi Gu; Huanmei Sun; Juan Shao; Hu Zhang; Zhanpeng Zhu; Dongqin Ma; Yingchun Duan

Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice

Volume 28, Issue 1, January 2025, Pages 87-97

10.22038/ijbms.2024.78454.16962

Jinshan Liu; Jinlong Hu; Hongyu Xu; Liang Yan; Jiaming Yao; Baoqiang Cao

Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice

Volume 27, Issue 12, December 2024, Pages 1515-1528

10.22038/ijbms.2024.78787.17037

Hojat Anbara; Maryam Ghorbani; Alireza Shahriary

Catalpol alleviates amyloid- generation and neuronal oxidative stress injury via activating the Keap1-Nrf2/ARE signaling pathway in the immortalized lymphocytes from patients with late-onset Alzheimer’s disease and SKNMC cells co-culture model

Volume 27, Issue 12, December 2024, Pages 1547-1557

10.22038/ijbms.2024.78543.16982

Caixia Xiang; Yunwei Lu; Renjuan Hao; Yuyan Wei; Yingchao Hu; Guran Yu

Baicalein blocked gastric cancer cell proliferation and invasion through modulated platelet type 12-lipoxygenase

Volume 27, Issue 12, December 2024, Pages 1574-1582

10.22038/ijbms.2024.80479.17422

Jing Ye; Dan Qiao; Yingying Zhang; Yingshi Piao; Jingchun Jin

Iranian Journal of Basic Medical Sciences

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