Iranian Journal of Basic Medical Sciences

Main Subjects = Genetics

Loss of neuraminidase 1 inhibits the activation of hepatic stellate cells through TGF-β/Smad3 signaling

Articles in Press, Accepted Manuscript, Available Online from 06 January 2026

10.22038/ijbms.2026.90987.19628

Yue Zhang; Yuan Song; Yuan Nie; Xuan Zhu; Bi-min Li; Chenkai Huang

Recent advances in the genetic engineering of the Leishmania parasite and anti-cancer properties

Volume 28, Issue 11, November 2025, Pages 1447-1455

10.22038/ijbms.2025.87919.18992

Saeid Rahim; Hossein Yousofi Darani; Hossein Khanahmad; Nadia Pourmoshir; Zahra Bakhshiyani; Sedigheh Saberi

CRISPR/Cas9 in colorectal cancer: Revolutionizing precision oncology through genome editing and targeted therapeutics

Volume 28, Issue 10, October 2025, Pages 1279-1300

10.22038/ijbms.2025.87531.18902

Bahjat Alhasso; Abdulkareem Shareef; Lalji Baldaniya; Rami Oweis; S. Renuka Jyothi; Udaybir Singh; Samir Sahoo; Ashish Singh Chauhan; Hayder Naji Sameer; Ahmed Yaseen; Zainab H. Athab; Mohaned Adil

Calpain 7 as a novel candidate gene in genetic generalized epilepsy

Volume 28, Issue 10, October 2025, Pages 1328-1334

10.22038/ijbms.2025.88053.19021

Faezeh Jamali; Mohammad Shariati; Mohammadtagi Farzadfard; Juliane Winkelmann; Mohsen Foroughipour; Mir Salar Kahaei; Ariane Sadr-Nabavi; Michael Zech

Non-coding RNAs as key players in neurodegeneration and brain tumors: Insights into therapeutic strategies

Volume 28, Issue 8, August 2025, Pages 962-985

10.22038/ijbms.2025.85350.18446

Mohamed Javad Saadh; Sarraa Ahmad Qahtan; Rafid Jihad Albadr; Gaurav Sanghvi; Rangaswamy Roopashree; Aditya Kashyap; A. Sabarivani; Jasur Rizaev; Waam Mohammed Taher; Mariem Alwan; Mahmod Jasem Jawad; Ali M. Ali Al-Nuaimi

Thymoquinone prevents valproic acid-induced hepatotoxicity via modulation of cytochrome P450, PPARs, and apoptotic pathways

Volume 28, Issue 7, July 2025, Pages 899-906

10.22038/ijbms.2025.85190.18407

Sebile Azirak; Sedat Bilgiç; Deniz Taştemir Korkmaz; İlkay Armağan; Mehmet Kaya Özer

Psoriasis: Immunological and genetic blueprints driving pathogenesis and potential for personalized therapies

Volume 28, Issue 6, June 2025, Pages 680-690

10.22038/ijbms.2025.85335.18442

Mohamed J. Saadh; Omer Qutaiba B. Allela; Radhwan Abdul Kareem; Gaurav Sanghvi; G. Padma Priya; Rishabh Thakur; Mukesh Kumari; Sofia Gupta; Kakhramon Khaitov; Hayder Naji Sameer; Ahmed Yaseen; Zainab H. Athab; Mohaned Adil

Salidroside impedes Ang II-infused myocardial fibrosis by activating the SIRT1-Nrf2 pathway

Volume 28, Issue 6, June 2025, Pages 815-824

10.22038/ijbms.2025.83659.18105

Xi Zhu; Zhen Hai; Zhongping Ning

Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer

Volume 28, Issue 5, May 2025, Pages 592-601

10.22038/ijbms.2025.81777.17688

Sara Chitgaran; Reihaneh Alsadat Mahmoudian; Seyed Saeed Khatami; Fatemeh Nasrabadi; Ehsan Soltani; Amirnader Emami Razavi; Fatemeh Kamali; Ahmad Reza Bahrami; Maryam Moghaddam Matin; Moein Farshchian

Bioinformatics analysis identifies dysregulation of MiR-548F-3p and its hub gene in triple-negative breast cancer

Volume 28, Issue 4, April 2025, Pages 434-443

10.22038/ijbms.2025.79808.17287

Samira Behroozi; Mahdieh Salimi; Najaf Allahyari Fard

Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways

Volume 28, Issue 4, April 2025, Pages 507-515

10.22038/ijbms.2025.79735.17270

Hasan Şimşek; Nurhan Akaras; Cihan Gur; Sefa Kucukler; Mustafa Ileriturk; Fatih Mehmet Kandemir

Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword

Volume 28, Issue 1, January 2025, Pages 3-15

10.22038/ijbms.2024.81644.17669

Negin Masoomabadi; Ali Gorji; Tahereh Ghadiri; Safieh Ebrahimi

Introduction of LPIN1 as a potential diagnostic and prognostic biomarker for gastric cancer via integrative bioinformatics analysis of a competing endogenous RNA network and experimental validation

Volume 27, Issue 11, November 2024, Pages 1456-1463

10.22038/ijbms.2024.74686.16216

Milad Daneshmand-Parsa; Parvaneh Nikpour

Andrographolide demonstrates anti-proliferative activity in oral cancer by promoting apoptosis, the programmed cell death process

Volume 27, Issue 10, October 2024, Pages 1300-1308

10.22038/ijbms.2024.76691.16599

Gauri Mansinh Kumbhar; Amol Dilip Jadhav; Supriya Kheur; Vaibhav Sunil Ladke

Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway

Volume 27, Issue 6, June 2024, Pages 717-724

10.22038/ijbms.2024.73281.15928

Xiaogang Zhang; Bei Tian; Xinpeng Cong; Zhongping Ning

Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation

Volume 27, Issue 5, May 2024, Pages 611-620

10.22038/ijbms.2024.75164.16299

Samaneh Rezaei; Mohammad Hasan Jafari Najaf Abadi; Mohammad Javad Bazyari; Amin Jalili; Reza Kazemi Oskuee; Seyed Hamid Aghaee-Bakhtiari

Insights into the radiotherapy-induced deferentially expressed RNAs in colorectal cancer management

Volume 26, Issue 12, December 2023, Pages 1380-1389

10.22038/ijbms.2023.71259.15482

Arezu Karimpur Zahmatkesh; Amin Moqadami; Mohammad Khalaj-Kondori

Evaluation of the expression profile of mRNAs and lncRNAs in cumulus cells associated with polycystic ovary syndrome and pregnancy

Volume 26, Issue 10, October 2023, Pages 1144-1154

10.22038/ijbms.2023.69829.15206

Behnaz Hammami; Fatemeh Sadat Mostafavi; Ali Akbari; Seyyed Reza Mousavi; Mohammad Kazemi

Deregulation of apoptotic proteins by induction of Dendropthae falcata (L.f.) Ettingsh plant extract in breast cancer cells: A proteome-wide analysis

Volume 26, Issue 10, October 2023, Pages 1202-1211

10.22038/ijbms.2023.71125.15450

Alwin Beschi Durairaj; Ananthi Sivaganam; Reginald Appavoo Monikam; Rajapandiyan Krishnamoorthy; Mohammad Z. Ahmed; Alqahtani Ali S.; Ponani Kaja Mideen