Iranian Journal of Basic Medical Sciences

Main Subjects = Pharmaceutical Sciences

Mitochondrial protection and anti-inflammatory effect of curcumin in inhibiting reproductive toxicity induced by sodium valproate in male mice

Volume 28, Issue 8, August 2025, Pages 1027-1036

10.22038/ijbms.2025.82254.17791

Moein Shaneh; Milad Chahardori; Fereshteh Talebpour Amiri; Nahid Amani; Fatemeh Shaki

The neuroprotective effects of hesperidin and diosmin in neurological disorders via targeting various signaling pathways

Volume 28, Issue 7, July 2025, Pages 825-834

10.22038/ijbms.2025.81908.17719

Nikoo Abharian; Noushin Nikray; Afsoon Feizi; Marjan Talebi; Hamed Shafaroodi; Mehrdad Faizi

Pulmonary delivery of insulin by dry powder inhaler formulations

Volume 28, Issue 7, July 2025, Pages 873-879

10.22038/ijbms.2025.83954.18168

Mohsen Imenshahidi; Mona Kabiri; Mohammad Jandaghi; Seyed Salman Razavi Rouhani; Khalil Abnous; Gholamreza Karimi; Mohsen Tafaghodi

Fabrication and assessment of ethosomes for effective transdermal delivery of loxoprofen

Volume 28, Issue 6, June 2025, Pages 728-738

10.22038/ijbms.2025.84183.18206

Sarah Jabbar Abd Alhur; Hasanain Shakir Mahmood

Black seed oil nanoemulsion containing albendazole against protoscoleces of Echinococcus granulosus: An in vivo study

Volume 28, Issue 6, June 2025, Pages 755-761

10.22038/ijbms.2025.83014.17942

Fatemeh Oroojaian; Tahereh Mohammadzadeh; Ailin Ebrahimzadeh; Peiman Aleshiekh; Reza Shafiei; Amir Amani

Investigating therapeutic efficacy of dacarbazine and temozolomide, alone and in combination with BRAF(V600E) siRNA in A375 human melanoma cell line

Volume 28, Issue 6, June 2025, Pages 772-783

10.22038/ijbms.2025.84187.18208

Fatemeh Tabandeh; Rana Moradian Tehrani; Mohammadreza Sharifi; Elmira Toopchi

Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery

Volume 28, Issue 5, May 2025, Pages 627-637

10.22038/ijbms.2025.81837.17706

Ramin Abrishami; Ramtin Farhadi; Mehri Farhang Ranjbar; Seyed Hadi Aghili; Maryam Baeeri

Nanomolecular silencing of TSC22D4 mRNA via a DNAsome-siRNA for enhancing insulin sensitization in hepatocytes

Volume 28, Issue 3, March 2025, Pages 385-392

10.22038/ijbms.2024.81998.17744

Ameneh Mohammadi; Pedram Ebrahimnejad; Saeid Abediankenari; Zahra Kashi; Pooria Gill

Nanoformulation innovations: Revolutionizing precision in migraine therapy

Volume 28, Issue 1, January 2025, Pages 16-30

10.22038/ijbms.2024.79824.17290

Mohammad Ghasemi Farimani; Fatemeh Kalalinia; Somayeh Marouzi; Sara Gheshlaghi; Zahra Salmasi; Maryam Hashemi

Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats

Volume 28, Issue 1, January 2025, Pages 56-62

10.22038/ijbms.2024.78131.16885

Meilinah Hidayat; Amirah Barnas; Virginia Nussy; Timothy Wantania; Sriwidodo Sriwidodo; Khomaini Hasan

Recent advancements in the role of phytochemicals and Medicinal plants in prophylaxis and management of Alzheimer’s disease

Volume 27, Issue 11, November 2024, Pages 1357-1369

10.22038/ijbms.2024.77760.16826

Akanksha Mishra; Sairam Krishnamurthy

C-71980262, A novel small molecule against human papilloma virus-16 E6 (HPV-16 E6) with anticancer potency against cervical cancer: A computational guided in vitro approach

Volume 27, Issue 11, November 2024, Pages 1389-1396

10.22038/ijbms.2024.78090.16882

Ashish Kumar

Medicinal potential of embelin and its nanoformulations: An update on the molecular mechanism and various applications

Volume 27, Issue 10, October 2024, Pages 1228-1242

10.22038/ijbms.2024.77888.16850

Asad Ali; Nasr Ali Emad; Niha Sultana; Hamad Ali; Samreen Jahan; Mohd Aqil; Mohd Mujeeb; Yasmin Sultana

Curcumin chitosan microspheres regulate Th17/Treg balance via IGF2BP1- mediated m6A modification of LRP5 in ulcerative colitis

Volume 27, Issue 10, October 2024, Pages 1276-1283

10.22038/ijbms.2024.76332.16535

Ling Chen; Yanru Xiang; Shirong Zhong; Yinglin Wu; Jiaqi Liu; Yan Wu; Zhizhi Wang; Guodong Huang

Synthesized diterpene lactone derivative attenuated Freund’s complete adjuvant-induced arthritis in Wistar rats

Volume 27, Issue 9, September 2024, Pages 1197-1208

10.22038/ijbms.2024.75023.16295

Patrick Francis Kimariyo; Sony Priya Kurati; Perupogu Suvarna Babu; Alfredi Alfred Moyo; Murali Krishna Kumar Muthyala

Lactosylated lipid calcium phosphate-based nanoparticles: A promising approach for efficient DNA delivery to hepatocytes

Volume 27, Issue 8, August 2024, Pages 952-958

10.22038/ijbms.2024.76683.16602

Masoomeh Khalifeh; Ali Badiee; Navid Ramezanian; Amirhossein Sahebkar; Atena Farahpour; Reza Kazemi Oskuee

Renoprotective effect of Limonium duriusculum (de Girard) Kuntze via modulation of oxidative stress/ UPR markers and inflammation during cyclosporine-induced nephrotoxicity in rats

Volume 27, Issue 8, August 2024, Pages 1023-1032

10.22038/ijbms.2024.77052.16661

Azzedine Redouane-Salah; Ameddah Souad; Kerkatou Wafa; Kamil Wojnicki; Adrian M. Ramos; Alberto Ortiz; Bozena Kaminska; Ahmed Menad

Effects of lupeol and flutamide on experimentally-induced polycystic ovary syndrome in mice

Volume 27, Issue 8, August 2024, Pages 1067-1076

10.22038/ijbms.2024.77602.16783

Ali Rezaei-Golmisheh; Rajabali Sadrkhanloo; Abbas Ahmadi; Hassan Malekinejad

Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL

Volume 27, Issue 7, July 2024, Pages 801-812

10.22038/ijbms.2024.76261.16498

Somayeh Yazdanparast; Davood Bashash; Amirsalar Nikkhah Bahrami; Mohammad Ghorbani; Mehrdad Izadirad; Mehdi Bakhtiyaridovvombaygi; Ahmad Gharehbaghian

N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis

Volume 27, Issue 7, July 2024, Pages 850-856

10.22038/ijbms.2024.72882.15853

Heng Fan; Le Jian-wei; sun Min; Zhu Jian-hua

How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions

Volume 27, Issue 7, July 2024, Pages 857-867

10.22038/ijbms.2024.75152.16292

Farnaz Khaleseh; Mohammad Barzegar-Jalali; Parvin Zakeri-Milani; Zahra Karami; Mohammad Reza Saghatchi Zanjani; Hadi Valizadeh

Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models

Volume 27, Issue 7, July 2024, Pages 868-878

10.22038/ijbms.2024.70825.15385

Wahyu Widowati; Ahmad Faried; Achmad Adam; Deni Rahmat; Hanna Sari Widya Kusuma; Nindia Salsabila Mia Dewi; Marisca Gondokesumo; Rizal Rizal; Ita Margaretha Nainggolan; Massoud Vosough