Iranian Journal of Basic Medical Sciences

Keyword Index

A

Acute kidney injury Mitigation of sepsis-associated acute kidney injury by thymoquinone via targeting pyroptosis and attenuation of inflammation in C57BL/6 mice [Volume 29, Issue 5, 2026, Pages 717-723]
Acute kidney injury Cordycepin ameliorates ischemia/reperfusion-induced acute kidney injury via inhibiting apoptosis and necroptosis [Volume 29, Issue 8, 2026, Pages 1218-1228]
Acute lung injury Syringic acid attenuates LPS-induced acute lung injury via modulation of the HMGB1/TLR4/NF-κB and Keap1/Nrf2/HO-1 pathways: Mechanistic insights from in vivo and in silico studies [Volume 29, Issue 2, 2026, Pages 302-312]
Adenosine A1 receptor AMP-activated protein- kinase Remote ischemic preconditioning protects heart via modulation of purinergic signaling and AMPK-mediated autophagy in rat model of ischemia reperfusion injury [Volume 29, Issue 4, 2026, Pages 558-569]
Adipose derived stem cells Synergistic myelin regenerative, immunomodulatory and anti-inflammatory effects of vanillin and adipose derived stem cells in cuprizone animal model of multiple sclerosis [Volume 29, Issue 7, 2026, Pages 1027-1034]
Aging Protective effects and mechanism of chrysophanol against age-related osteoporosis in rats [Volume 29, Issue 5, 2026, Pages 724-729]
Aging Role of gallic acid in sarcopenia in D-galactose-treated mice [Volume 29, Issue 7, 2026, Pages 1035-1042]
Airway inflammation 1,25-Dihydroxyvitamin D3 ameliorates neutrophilic asthma through modulation of ERS-NLRP3 inflammasome axis in a mouse model [Volume 29, Issue 3, 2026, Pages 438-445]
Albendazole (ABZ) Recent advances in the detection and treatment of hydatid cysts by nanomaterial-based carriers [Volume 29, Issue 5, 2026, Pages 657-674]
Alcohol Trigonelline protects against alcohol-induced brain damage by inhibition of oxidative stress, TLR4/NF-κB/proinflammatory cytokines pathway, and apoptosis [Volume 29, Issue 7, 2026, Pages 1079-1088]
Alendronate Preparation and characterization of decellularized bovine bone as a bioscaffold for bone tissue engineering applications [Volume 29, Issue 1, 2026, Pages 128-137]
Allele-specific Allele-specific disruption of KRAS p.G12V in colorectal cancer cells using electroporated Cas9 RNPs [Volume 29, Issue 8, 2026, Pages 1278-1285]
Allergic contact dermatitis STAT3 ablation in keratinocytes ameliorates allergic contact dermatitis in DNCB-induced mice model [Volume 29, Issue 6, 2026, Pages 961-970]
Alpha subunit Cannabidiol attenuates lung ischemia-reperfusion injury by modulating RIPK1/RIPK3-mediated necroptosis and HIF-1α/VEGF signaling [Volume 29, Issue 5, 2026, Pages 766-773]
Alpha-synuclein CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease [Volume 29, Issue 6, 2026, Pages 915-926]
Alzheimer disease RNA Comparison of long non-coding RNA NEAT1 expression, P53, and antioxidant factors between Alzheimer’s patients and healthy individuals [Volume 29, Issue 4, 2026, Pages 598-604]
Alzheimer&rsquo Investigation of neuroprotective and antiapoptotic effects of rosmarinic acid in an in vitro Alzheimer’s disease model [Volume 29, Issue 8, 2026, Pages 1241-1248]
Alzheimer’s Raspberry protective role in inflammatory diseases: An overview [Volume 29, Issue 1, 2026, Pages 22-33]
Alzheimer’s disease Rosemary (Rosmarinus officinalis L.) and nervous system disorders: New findings on its neuroprotective properties [Volume 29, Issue 2, 2026, Pages 155-180]
Alzheimer’s disease Targeting amyloid-β in Alzheimer’s disease: A critical analysis of clinical trials and their implications for drug development [Volume 29, Issue 4, 2026, Pages 531-543]
Alzheimer’s disease Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling [Volume 29, Issue 3, 2026, Pages 423-437]
Alzheimer’s disease Huanglian Jiedu decoction ameliorates Alzheimer’s disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes [Volume 29, Issue 6, 2026, Pages 927-934]
Amaranthaceae Evaluation of cytotoxic, anti-oxidant, and apoptotic effects of Dysphania botrys extract on B16F10 and MCF-7 cell lines [Volume 29, Issue 1, 2026, Pages 74-80]
Amarogentin Amarogentin relieves cholestatic liver injury caused by ANIT in rats by regulating the FXR and Nrf2 pathways [Volume 29, Issue 1, 2026, Pages 65-73]
Amniotic membrane Characterization of exosomes from hypoxia-activated human amniotic membrane mesenchymal stem cells [Volume 29, Issue 4, 2026, Pages 544-557]
Amyloid beta-peptides- (1-42) Huanglian Jiedu decoction ameliorates Alzheimer’s disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes [Volume 29, Issue 6, 2026, Pages 927-934]
Amyloid neuropathies Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey [Volume 29, Issue 6, 2026, Pages 812-822]
Analgesia Inhibition of the PKC-TRPV1-SP axis by propolis ameliorates chronic inflammatory pain in mice [Volume 29, Issue 5, 2026, Pages 744-751]
Angiotensin II Cardiovascular effects of ventrolateral periaqueductal gray (vlPAG) AT1 receptors in normotensive and hemorrhagic rats [Volume 29, Issue 2, 2026, Pages 290-301]
Animal models Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD [Volume 29, Issue 2, 2026, Pages 231-239]
Animal models Radiotherapy-associated changes in the miR-124/SP1 axis in a rat glioma model [Volume 29, Issue 8, 2026, Pages 1211-1217]
ANT1 Involvement of SIRT3 downstream targets ANT1, VDAC, CYPD, and Drp1 in a rat model of hepatic encephalopathy: Therapeutic role of thymoquinone [Volume 29, Issue 6, 2026, Pages 952-960]
Anti-apoptotic Metformin alleviates anti-oxidant and anti-apoptotic effects by regulating the Nrf2/HO-1 signaling pathway in a rat model of testicular ischemia/reperfusion [Volume 29, Issue 3, 2026, Pages 482-487]
Antibacterial peptide Fabrication of a five-layer wound dressing containing chitosan-LL37 peptide for the treatment of EB wounds and deep exudate patients [Volume 29, Issue 8, 2026, Pages 1229-1240]
Antibodies Antibody therapies in glioblastoma: Overcoming micro-environmental barriers [Volume 29, Issue 3, 2026, Pages 353-377]
Antibody-drug conjugates Antibody therapies in glioblastoma: Overcoming micro-environmental barriers [Volume 29, Issue 3, 2026, Pages 353-377]
Anti-inflammation Inhibition of the PKC-TRPV1-SP axis by propolis ameliorates chronic inflammatory pain in mice [Volume 29, Issue 5, 2026, Pages 744-751]
Anti-inflammatory agents Beyond bioactivity: Chitosan macromolecular coatings on titanium surfaces drive osseointegration and immune suppression through targeted epigenetic regulation [Volume 29, Issue 7, 2026, Pages 1066-1078]
Antineoplastic agents Repurposing an antimicrobial arginine-rich decapeptide as a novel anticancer agent: Evidence from in vitro and in vivo breast cancer models [Volume 29, Issue 5, 2026, Pages 736-743]
Anti-oxidant Evaluation of cytotoxic, anti-oxidant, and apoptotic effects of Dysphania botrys extract on B16F10 and MCF-7 cell lines [Volume 29, Issue 1, 2026, Pages 74-80]
Anti-oxidant Metformin alleviates anti-oxidant and anti-apoptotic effects by regulating the Nrf2/HO-1 signaling pathway in a rat model of testicular ischemia/reperfusion [Volume 29, Issue 3, 2026, Pages 482-487]
Anti-oxidant Effects of minocycline on acrylamide-induced neurotoxicity in Wistar rats [Volume 29, Issue 3, 2026, Pages 393-400]
Anti-oxidant Trans sodium crocetinate protects against hepatotoxicity induced by bisphenol A in rats [Volume 29, Issue 4, 2026, Pages 570-577]
Anti-oxidant activity Hispidulin: A potential antihyperglycemic and anti-oxidant agent-mechanistic insights into its modulatory effects on PI3K, AKT, mTOR, IRS1, GSK-3β, and GLUT-4 pathways through in vitro and in vivo studies [Volume 29, Issue 2, 2026, Pages 240-248]
Anti-oxidant response HIPK2 protects neurons from oxidative stress and modulates central nervous system responses following traumatic brain injury [Volume 29, Issue 5, 2026, Pages 804-811]
Anti-Oxidants Neuroprotective effects of kojic acid and nano-kojic acid in experimental brain ischemia induced by bilateral common carotid artery occlusion [Volume 29, Issue 1, 2026, Pages 43-54]
Anti-Oxidants The role of oxidative stress in sleep deprivation-induced reproductive dysfunction: A rationale for anti-oxidant intervention [Volume 29, Issue 2, 2026, Pages 191-201]
Anti-Oxidants An in vivo evaluation of the antifibrotic potential of inulin against bile duct ligation-induced liver fibrosis [Volume 29, Issue 2, 2026, Pages 271-279]
Anti-PD-1 Modulation of CCL5 and CXCR4 as EMT signaling biomarkers by cold atmospheric plasma and Anti-PD-1 combination therapy in melanoma: Insights from integrated bioinformatics and in vitro and in vivo validation [Volume 29, Issue 7, 2026, Pages 1052-1065]
Antitubercular agents A review on recent advances in lipid-based drug delivery systems for tuberculosis [Volume 29, Issue 3, 2026, Pages 322-333]
Anxiety Rosemary (Rosmarinus officinalis L.) and nervous system disorders: New findings on its neuroprotective properties [Volume 29, Issue 2, 2026, Pages 155-180]
Anxiety The effect of tert-butylhydroquinone on anxiolytic- and antidepressant-like behaviors induced by post-traumatic stress disorder: A behavioral and molecular study [Volume 29, Issue 1, 2026, Pages 113-120]
Apoptosis Evaluation of cytotoxic, anti-oxidant, and apoptotic effects of Dysphania botrys extract on B16F10 and MCF-7 cell lines [Volume 29, Issue 1, 2026, Pages 74-80]
Apoptosis 18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats [Volume 29, Issue 1, 2026, Pages 81-89]
Apoptosis The protective effect of resveratrol on lupus nephritis mice by up-regulating Sirt1 [Volume 29, Issue 1, 2026, Pages 138-144]
Apoptosis Protocatechuic acid mitigates diazinon-induced lung injury in rats through modulation of oxidative stress, inflammatory, Keap-1/Nrf-2/HO-1 and ER stress-mediated apoptotic pathways [Volume 29, Issue 2, 2026, Pages 261-270]
Apoptosis Effects of minocycline on acrylamide-induced neurotoxicity in Wistar rats [Volume 29, Issue 3, 2026, Pages 393-400]
Apoptosis Trans sodium crocetinate protects against hepatotoxicity induced by bisphenol A in rats [Volume 29, Issue 4, 2026, Pages 570-577]
Apoptosis Synergistic induction of apoptosis in cancer cells by combined silver nanoparticles and paclitaxel [Volume 29, Issue 4, 2026, Pages 634-640]
Apoptosis Comparison of long non-coding RNA NEAT1 expression, P53, and antioxidant factors between Alzheimer’s patients and healthy individuals [Volume 29, Issue 4, 2026, Pages 598-604]
Apoptosis Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats [Volume 29, Issue 4, 2026, Pages 623-633]
Apoptosis Repurposing an antimicrobial arginine-rich decapeptide as a novel anticancer agent: Evidence from in vitro and in vivo breast cancer models [Volume 29, Issue 5, 2026, Pages 736-743]
Apoptosis Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis [Volume 29, Issue 6, 2026, Pages 844-869]
Apoptosis Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/Caspase-3, and TLR4/NF-κB axis activatione [Volume 29, Issue 6, 2026, Pages 942-951]
Apoptosis Combined effects of EGCG and retinol on viability and apoptosis-related gene expression in Caco-2 and HCT-116 colon cancer cells [Volume 29, Issue 6, 2026, Pages 909-914]
Apoptosis CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease [Volume 29, Issue 6, 2026, Pages 915-926]
Apoptosis Investigating the protective effect of zinc supplementation on streptozotocin-induced pancreatic beta-cell damage via the HMGB1/TLR2/MAPK pathway [Volume 29, Issue 7, 2026, Pages 1020-1026]
Apoptosis Protective efficacy of thymol in testicular ischemia/reperfusion injury in rats: A biochemical and histopathological evaluation [Volume 29, Issue 7, 2026, Pages 1115-1121]
Apoptosis Role of gallic acid in sarcopenia in D-galactose-treated mice [Volume 29, Issue 7, 2026, Pages 1035-1042]
Apoptosis Rosemary inhalation improves the behavior and cognition of vascular cognitive impairment rats by regulating SIRT1/mTOR pathway-mediated cell apoptosis and autophagy [Volume 29, Issue 8, 2026, Pages 1269-1277]
Apoptosis Cordycepin ameliorates ischemia/reperfusion-induced acute kidney injury via inhibiting apoptosis and necroptosis [Volume 29, Issue 8, 2026, Pages 1218-1228]
Apoptosis Investigation of neuroprotective and antiapoptotic effects of rosmarinic acid in an in vitro Alzheimer’s disease model [Volume 29, Issue 8, 2026, Pages 1241-1248]
Apoptosis Resveratrol mitigates diazinon-induced neurotoxicity during fetal brain development [Volume 29, Issue 8, 2026, Pages 1249-1258]
APP Targeting amyloid-β in Alzheimer’s disease: A critical analysis of clinical trials and their implications for drug development [Volume 29, Issue 4, 2026, Pages 531-543]
Artificial intelligence Antibody therapies in glioblastoma: Overcoming micro-environmental barriers [Volume 29, Issue 3, 2026, Pages 353-377]
Artificial intelligence Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer [Volume 29, Issue 5, 2026, Pages 688-716]
Artificial intelligence AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery [Volume 29, Issue 6, 2026, Pages 823-843]
Artificial neural network Fabrication and analysis of a PVP-carboxymethyl chitosan/forsterite nanocomposite scaffold with stainless steel base via freeze-drying and neural network techniques [Volume 29, Issue 1, 2026, Pages 101-112]
Atherosclerosis Ashwagandha (Withania somnifera) in insulin resistance and metabolic syndrome: A literature review on mechanisms [Volume 29, Issue 1, 2026, Pages 3-21]
Atherosclerosis Raspberry protective role in inflammatory diseases: An overview [Volume 29, Issue 1, 2026, Pages 22-33]
Atherosclerosis Ponicidin alleviates atherosclerosis by inhibiting inflammation and oxidative stress through the SIRT1 and PI3K/Akt pathway [Volume 29, Issue 8, 2026, Pages 1195-1201]
Autism spectrum disorder Promising therapeutic efficacy of kolaviron against prenatal valproate-induced autism spectrum disorder [Volume 29, Issue 8, 2026, Pages 1202-1210]
Autophagic Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity [Volume 29, Issue 1, 2026, Pages 90-100]
Autophagy Remote ischemic preconditioning protects heart via modulation of purinergic signaling and AMPK-mediated autophagy in rat model of ischemia reperfusion injury [Volume 29, Issue 4, 2026, Pages 558-569]
Autophagy Eugenol attenuates paclitaxel-induced cardiotoxicity by modulating autophagy-related markers in rats [Volume 29, Issue 5, 2026, Pages 794-803]
Autophagy Role of gallic acid in sarcopenia in D-galactose-treated mice [Volume 29, Issue 7, 2026, Pages 1035-1042]
Autophagy Rosemary inhalation improves the behavior and cognition of vascular cognitive impairment rats by regulating SIRT1/mTOR pathway-mediated cell apoptosis and autophagy [Volume 29, Issue 8, 2026, Pages 1269-1277]
Aβ Targeting amyloid-β in Alzheimer’s disease: A critical analysis of clinical trials and their implications for drug development [Volume 29, Issue 4, 2026, Pages 531-543]

B

BACE1 Targeting amyloid-β in Alzheimer’s disease: A critical analysis of clinical trials and their implications for drug development [Volume 29, Issue 4, 2026, Pages 531-543]
Berberine The effect(s) of berberine from Berberis vulgaris L. (Berberidaceae) on treating type 1 diabetes mellitus in streptozotocin-induced diabetic rats [Volume 29, Issue 4, 2026, Pages 613-622]
Bile duct ligation An in vivo evaluation of the antifibrotic potential of inulin against bile duct ligation-induced liver fibrosis [Volume 29, Issue 2, 2026, Pages 271-279]
Bile duct ligation Effects of glucocorticoid on cardiac chronotropic responsiveness in cirrhotic rats: A possible role for dopamine receptors [Volume 29, Issue 6, 2026, Pages 893-900]
Bile duct ligation (BDL) Time-dependent modulation of FXR and Nrf2 signaling in rat models of BDL-induced cholestasis [Volume 29, Issue 7, 2026, Pages 1012-1019]
Biocompatibility Characterization of exosomes from hypoxia-activated human amniotic membrane mesenchymal stem cells [Volume 29, Issue 4, 2026, Pages 544-557]
Biocompatible materials Evaluation of differentiation of the umbilical cord blood-derived mesenchymal stem cells into male germ-line cells in two-dimensional and three-dimensional scaffolds containing naringin [Volume 29, Issue 2, 2026, Pages 249-260]
Bioinformatics Loss of neuraminidase 1 inhibits the activation of hepatic stellate cells through TGF-β/Smad3 signaling [Volume 29, Issue 3, 2026, Pages 387-392]
Biological macromolecules Beyond bioactivity: Chitosan macromolecular coatings on titanium surfaces drive osseointegration and immune suppression through targeted epigenetic regulation [Volume 29, Issue 7, 2026, Pages 1066-1078]
Biomarkers Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer [Volume 29, Issue 5, 2026, Pages 688-716]
Biomedicine Smart micro/nanoneedles for gene delivery [Volume 29, Issue 7, 2026, Pages 991-1011]
Biomineralization Enhanced bone regeneration and cellular protection from oxidative stress using a vitamin C-based scaffold [Volume 29, Issue 2, 2026, Pages 280-289]
Bisphenol A Trans sodium crocetinate protects against hepatotoxicity induced by bisphenol A in rats [Volume 29, Issue 4, 2026, Pages 570-577]
Blood-brain barrier The role of exosomes in brain tumors: Mechanisms, diagnosis, and therapeutic prospects [Volume 29, Issue 3, 2026, Pages 313-321]
Blood-brain barrier Antibody therapies in glioblastoma: Overcoming micro-environmental barriers [Volume 29, Issue 3, 2026, Pages 353-377]
Bone destruction CD73 blockade alleviates collagen-induced arthritis by inhibiting synovial fibroblast activity [Volume 29, Issue 5, 2026, Pages 774-781]
Bone Diseases/Metabolic Protective effects and mechanism of chrysophanol against age-related osteoporosis in rats [Volume 29, Issue 5, 2026, Pages 724-729]
Bone scaffold Fabrication and analysis of a PVP-carboxymethyl chitosan/forsterite nanocomposite scaffold with stainless steel base via freeze-drying and neural network techniques [Volume 29, Issue 1, 2026, Pages 101-112]
Bone tissue engineering Preparation and characterization of decellularized bovine bone as a bioscaffold for bone tissue engineering applications [Volume 29, Issue 1, 2026, Pages 128-137]
Brain 18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats [Volume 29, Issue 1, 2026, Pages 81-89]
Brain Prenatal morphine exposure induces molecular and structural alterations in the developing hippocampus of neonatal rats [Volume 29, Issue 2, 2026, Pages 212-217]
Brain diseases Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis [Volume 29, Issue 6, 2026, Pages 844-869]
Brain neoplasms Non-coding RNAs related to PD1/PD-L1 signaling with potential diagnostic, prognostic, and therapeutic value in the tumorigenesis of brain cancers [Volume 29, Issue 8, 2026, Pages 1174-1183]
Breast neoplasms An in vivo study on sonodynamic effects mediated by nanomicelles containing PpIX as a sonosensitizing agent [Volume 29, Issue 2, 2026, Pages 225-230]
Breast neoplasms AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery [Volume 29, Issue 6, 2026, Pages 823-843]

C

Calcium Huanglian Jiedu decoction ameliorates Alzheimer’s disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes [Volume 29, Issue 6, 2026, Pages 927-934]
Cancer Raspberry protective role in inflammatory diseases: An overview [Volume 29, Issue 1, 2026, Pages 22-33]
Cancer In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3 [Volume 29, Issue 3, 2026, Pages 401-411]
Cannabidiol Cannabidiol: Pharmaceutical formulations and biomedical applications [Volume 29, Issue 4, 2026, Pages 522-530]
Cannabidiol Cannabidiol attenuates lung ischemia-reperfusion injury by modulating RIPK1/RIPK3-mediated necroptosis and HIF-1α/VEGF signaling [Volume 29, Issue 5, 2026, Pages 766-773]
Cannabis sativa Cannabidiol: Pharmaceutical formulations and biomedical applications [Volume 29, Issue 4, 2026, Pages 522-530]
Carboxymethyl chitosan Therapeutic potential of a pullulan polysaccharide-based hydrogel with antibacterial peptide for skin wound healing [Volume 29, Issue 3, 2026, Pages 412-422]
Carcinoma Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer [Volume 29, Issue 5, 2026, Pages 688-716]
Carcinoma Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [Volume 29, Issue 6, 2026, Pages 870-882]
Cardiac fibrosis In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3 [Volume 29, Issue 3, 2026, Pages 401-411]
Cardiac hypertrophy Nerolidol attenuates cardiac hypertrophy and fibrosis in mice: Modulation of collagen type I, apoptotic and endothelial gene expression [Volume 29, Issue 7, 2026, Pages 1100-1106]
Cardiac inflammation In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3 [Volume 29, Issue 3, 2026, Pages 401-411]
Cardiomyopathy Effects of glucocorticoid on cardiac chronotropic responsiveness in cirrhotic rats: A possible role for dopamine receptors [Volume 29, Issue 6, 2026, Pages 893-900]
Cardioprotection Remote ischemic preconditioning protects heart via modulation of purinergic signaling and AMPK-mediated autophagy in rat model of ischemia reperfusion injury [Volume 29, Issue 4, 2026, Pages 558-569]
Cardiotoxicity In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3 [Volume 29, Issue 3, 2026, Pages 401-411]
Cardiovascular Raspberry protective role in inflammatory diseases: An overview [Volume 29, Issue 1, 2026, Pages 22-33]
Cardiovascular system Cardiovascular effects of ventrolateral periaqueductal gray (vlPAG) AT1 receptors in normotensive and hemorrhagic rats [Volume 29, Issue 2, 2026, Pages 290-301]
Cardiovascular tissue-engineering Comparative evaluation of cell types for endothelialization in cardiovascular tissue engineering [Volume 29, Issue 7, 2026, Pages 979-990]
Carrier Smart micro/nanoneedles for gene delivery [Volume 29, Issue 7, 2026, Pages 991-1011]
C-C motif chemokine ligand - 5 (CCL5) Modulation of CCL5 and CXCR4 as EMT signaling biomarkers by cold atmospheric plasma and Anti-PD-1 combination therapy in melanoma: Insights from integrated bioinformatics and in vitro and in vivo validation [Volume 29, Issue 7, 2026, Pages 1052-1065]
CD44 Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [Volume 29, Issue 6, 2026, Pages 870-882]
CD73 CD73 blockade alleviates collagen-induced arthritis by inhibiting synovial fibroblast activity [Volume 29, Issue 5, 2026, Pages 774-781]
Cell cycle/drug effects Repurposing an antimicrobial arginine-rich decapeptide as a novel anticancer agent: Evidence from in vitro and in vivo breast cancer models [Volume 29, Issue 5, 2026, Pages 736-743]
Cell line Investigation of neuroprotective and antiapoptotic effects of rosmarinic acid in an in vitro Alzheimer’s disease model [Volume 29, Issue 8, 2026, Pages 1241-1248]
Cellular reprogramming Phenotypic alterations in the immune system and tolerance induction in tumor-draining lymph nodes [Volume 29, Issue 4, 2026, Pages 488-497]
Cellular therapy Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]
Cervical Cancer In vivo assessment of imoxide and diluted vitamin C’s inhibitory effects on cervical cancer in mice [Volume 29, Issue 6, 2026, Pages 971-978]
Chelator Synthesis, radiolabeling, and biodistribution evaluation of novel hyperbranched polyglycerols-based radiotracers for targeting PSMA in prostate cancer [Volume 29, Issue 7, 2026, Pages 1089-1099]
Chimeric antigen receptor Comparative analysis of second and third-generation nanobody-based CAR-NK cells targeting PSMA in prostate cancer immunotherapy: In silico and in vitro studies [Volume 29, Issue 7, 2026, Pages 1122-1130]
Chitosan Fabrication of a five-layer wound dressing containing chitosan-LL37 peptide for the treatment of EB wounds and deep exudate patients [Volume 29, Issue 8, 2026, Pages 1229-1240]
Chitosan coating Beyond bioactivity: Chitosan macromolecular coatings on titanium surfaces drive osseointegration and immune suppression through targeted epigenetic regulation [Volume 29, Issue 7, 2026, Pages 1066-1078]
Cholestatic liver injury Time-dependent modulation of FXR and Nrf2 signaling in rat models of BDL-induced cholestasis [Volume 29, Issue 7, 2026, Pages 1012-1019]
Chronic lymphocytic leukemia (CLL) Bioinformatic analysis and characterization of the Anti-CD20 scFv-Conjugated Fe₃O₄ nanoparticles for targeted therapy of CD20⁺ leukemia cells [Volume 29, Issue 8, 2026, Pages 1259-1268]
Chronic Obstructive Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD [Volume 29, Issue 2, 2026, Pages 231-239]
Chronic wounds Conditioned medium from mesenchymal stem cells: Towards skin tissue engineering and wound healing [Volume 29, Issue 2, 2026, Pages 181-190]
Chrysophanol Protective effects and mechanism of chrysophanol against age-related osteoporosis in rats [Volume 29, Issue 5, 2026, Pages 724-729]
Cinnamophilin Cinnamophilin ameliorates testosterone-induced prostatic hyperplasia and fibrosis by regulating 5α-reductase and TGF-β/Smad signaling pathway [Volume 29, Issue 1, 2026, Pages 121-127]
Ciprofloxacin Enhancing clomipramine antidepressive effect using nanocomplexes via different routes of administration: A comparative study [Volume 29, Issue 1, 2026, Pages 55-64]
Circadian Rhythm AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery [Volume 29, Issue 6, 2026, Pages 823-843]
Cirrhosis Effects of glucocorticoid on cardiac chronotropic responsiveness in cirrhotic rats: A possible role for dopamine receptors [Volume 29, Issue 6, 2026, Pages 893-900]
Cognitive impairment Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling [Volume 29, Issue 3, 2026, Pages 423-437]
Cognitive impairment Rosemary inhalation improves the behavior and cognition of vascular cognitive impairment rats by regulating SIRT1/mTOR pathway-mediated cell apoptosis and autophagy [Volume 29, Issue 8, 2026, Pages 1269-1277]
Cold atmospheric plasma - (CAP) Modulation of CCL5 and CXCR4 as EMT signaling biomarkers by cold atmospheric plasma and Anti-PD-1 combination therapy in melanoma: Insights from integrated bioinformatics and in vitro and in vivo validation [Volume 29, Issue 7, 2026, Pages 1052-1065]
Colorectal cancer Combined effects of EGCG and retinol on viability and apoptosis-related gene expression in Caco-2 and HCT-116 colon cancer cells [Volume 29, Issue 6, 2026, Pages 909-914]
Colorectal cancer Allele-specific disruption of KRAS p.G12V in colorectal cancer cells using electroporated Cas9 RNPs [Volume 29, Issue 8, 2026, Pages 1278-1285]
Conditional knockout DNCB STAT3 ablation in keratinocytes ameliorates allergic contact dermatitis in DNCB-induced mice model [Volume 29, Issue 6, 2026, Pages 961-970]
Conditioned medium Conditioned medium from mesenchymal stem cells: Towards skin tissue engineering and wound healing [Volume 29, Issue 2, 2026, Pages 181-190]
Cordycepin Cordycepin ameliorates ischemia/reperfusion-induced acute kidney injury via inhibiting apoptosis and necroptosis [Volume 29, Issue 8, 2026, Pages 1218-1228]
CRISPR Allele-specific disruption of KRAS p.G12V in colorectal cancer cells using electroporated Cas9 RNPs [Volume 29, Issue 8, 2026, Pages 1278-1285]
CRISPR/Cas9 CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease [Volume 29, Issue 6, 2026, Pages 915-926]
CRISPR-Cas systems AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery [Volume 29, Issue 6, 2026, Pages 823-843]
Crocin Preparation and characterization of decellularized bovine bone as a bioscaffold for bone tissue engineering applications [Volume 29, Issue 1, 2026, Pages 128-137]
C-X-C chemokine receptor - type 4 (CXCR4) Modulation of CCL5 and CXCR4 as EMT signaling biomarkers by cold atmospheric plasma and Anti-PD-1 combination therapy in melanoma: Insights from integrated bioinformatics and in vitro and in vivo validation [Volume 29, Issue 7, 2026, Pages 1052-1065]
Cyclophosphamide In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3 [Volume 29, Issue 3, 2026, Pages 401-411]
CYPD Involvement of SIRT3 downstream targets ANT1, VDAC, CYPD, and Drp1 in a rat model of hepatic encephalopathy: Therapeutic role of thymoquinone [Volume 29, Issue 6, 2026, Pages 952-960]
Cystic Echinococcosis Recent advances in the detection and treatment of hydatid cysts by nanomaterial-based carriers [Volume 29, Issue 5, 2026, Pages 657-674]
Cytocompatibility Enhanced bone regeneration and cellular protection from oxidative stress using a vitamin C-based scaffold [Volume 29, Issue 2, 2026, Pages 280-289]
Cytokines Fluoxetine attenuates UPR-activation, neuroinflammation, and oxidative stress in a nitroglycerin-induced rat model of migraine [Volume 29, Issue 3, 2026, Pages 458-467]
Cytokines Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling [Volume 29, Issue 3, 2026, Pages 423-437]
Cytotoxicity Evaluation of cytotoxic, anti-oxidant, and apoptotic effects of Dysphania botrys extract on B16F10 and MCF-7 cell lines [Volume 29, Issue 1, 2026, Pages 74-80]

D

Decellularized bone - scaffolds Preparation and characterization of decellularized bovine bone as a bioscaffold for bone tissue engineering applications [Volume 29, Issue 1, 2026, Pages 128-137]
Delta Delta opioid peptide (D-Ala2, D-Leu5)-enkephalin (DADLE) mitigates myocardial ischemia-reperfusion injury by inhibiting the TRAF6/NF-κB/NLRP3 pathway [Volume 29, Issue 2, 2026, Pages 218-224]
Depression Rosemary (Rosmarinus officinalis L.) and nervous system disorders: New findings on its neuroprotective properties [Volume 29, Issue 2, 2026, Pages 155-180]
Depression The effect of tert-butylhydroquinone on anxiolytic- and antidepressant-like behaviors induced by post-traumatic stress disorder: A behavioral and molecular study [Volume 29, Issue 1, 2026, Pages 113-120]
Depression Enhancing clomipramine antidepressive effect using nanocomplexes via different routes of administration: A comparative study [Volume 29, Issue 1, 2026, Pages 55-64]
Dexamethasone Effects of glucocorticoid on cardiac chronotropic responsiveness in cirrhotic rats: A possible role for dopamine receptors [Volume 29, Issue 6, 2026, Pages 893-900]
Dexmedetomidine Dexmedetomidine protects against ischemia and reperfusion-induced kidney injury in rats by inhibiting the expression of TRPM2 and TRPA1 channels [Volume 29, Issue 4, 2026, Pages 590-597]
Di-(2-ethylhexyl) phthalate Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/Caspase-3, and TLR4/NF-κB axis activatione [Volume 29, Issue 6, 2026, Pages 942-951]
Diabetes Mellitus 18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats [Volume 29, Issue 1, 2026, Pages 81-89]
Diabetes Mellitus Investigating the protective effect of zinc supplementation on streptozotocin-induced pancreatic beta-cell damage via the HMGB1/TLR2/MAPK pathway [Volume 29, Issue 7, 2026, Pages 1020-1026]
Diabetes mellitus type 1 The effect(s) of berberine from Berberis vulgaris L. (Berberidaceae) on treating type 1 diabetes mellitus in streptozotocin-induced diabetic rats [Volume 29, Issue 4, 2026, Pages 613-622]
Diabetic foot ulcers Conditioned medium from mesenchymal stem cells: Towards skin tissue engineering and wound healing [Volume 29, Issue 2, 2026, Pages 181-190]
Diazinon Protocatechuic acid mitigates diazinon-induced lung injury in rats through modulation of oxidative stress, inflammatory, Keap-1/Nrf-2/HO-1 and ER stress-mediated apoptotic pathways [Volume 29, Issue 2, 2026, Pages 261-270]
Diazinon Resveratrol mitigates diazinon-induced neurotoxicity during fetal brain development [Volume 29, Issue 8, 2026, Pages 1249-1258]
Digital twins Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer [Volume 29, Issue 5, 2026, Pages 688-716]
Dopamine receptors Effects of glucocorticoid on cardiac chronotropic responsiveness in cirrhotic rats: A possible role for dopamine receptors [Volume 29, Issue 6, 2026, Pages 893-900]
Doxorubicin Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats [Volume 29, Issue 4, 2026, Pages 623-633]
Doxorubicin Development of a hybrid micelle–hydrogel system for topical delivery of doxorubicin to skin cancer cells [Volume 29, Issue 8, 2026, Pages 1184-1194]
DRP1 Involvement of SIRT3 downstream targets ANT1, VDAC, CYPD, and Drp1 in a rat model of hepatic encephalopathy: Therapeutic role of thymoquinone [Volume 29, Issue 6, 2026, Pages 952-960]
Drug Delivery A review on recent advances in lipid-based drug delivery systems for tuberculosis [Volume 29, Issue 3, 2026, Pages 322-333]
Drug Delivery Recent advances in the detection and treatment of hydatid cysts by nanomaterial-based carriers [Volume 29, Issue 5, 2026, Pages 657-674]
Drug delivery systems The role of exosomes in brain tumors: Mechanisms, diagnosis, and therapeutic prospects [Volume 29, Issue 3, 2026, Pages 313-321]
Drug delivery systems Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [Volume 29, Issue 6, 2026, Pages 870-882]
Drug delivery systems Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey [Volume 29, Issue 6, 2026, Pages 812-822]
Dual-function peptide Repurposing an antimicrobial arginine-rich decapeptide as a novel anticancer agent: Evidence from in vitro and in vivo breast cancer models [Volume 29, Issue 5, 2026, Pages 736-743]
Dyslipidemia Ashwagandha (Withania somnifera) in insulin resistance and metabolic syndrome: A literature review on mechanisms [Volume 29, Issue 1, 2026, Pages 3-21]
Dysphania botrys Evaluation of cytotoxic, anti-oxidant, and apoptotic effects of Dysphania botrys extract on B16F10 and MCF-7 cell lines [Volume 29, Issue 1, 2026, Pages 74-80]

E

Electroacupuncture Electroacupuncture improves hypoxic stress and energy metabolism to alleviate vascular cognitive impairment through activation of the HIF-1α/p53/NGB signaling pathway in rats [Volume 29, Issue 1, 2026, Pages 34-42]
Electroporation Allele-specific disruption of KRAS p.G12V in colorectal cancer cells using electroporated Cas9 RNPs [Volume 29, Issue 8, 2026, Pages 1278-1285]
Embryonic stem cells (escs) Comparative evaluation of cell types for endothelialization in cardiovascular tissue engineering [Volume 29, Issue 7, 2026, Pages 979-990]
EMT Cinnamophilin ameliorates testosterone-induced prostatic hyperplasia and fibrosis by regulating 5α-reductase and TGF-β/Smad signaling pathway [Volume 29, Issue 1, 2026, Pages 121-127]
Endometrial neoplasms Comparative effects of estradiol and daidzein on the expression of endometrial cancer-related genes and histopathological parameters in the uterus of ovariectomized rats [Volume 29, Issue 1, 2026, Pages 145-154]
Endometriosis Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity [Volume 29, Issue 1, 2026, Pages 90-100]
Endoplasmic reticulum - stress 18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats [Volume 29, Issue 1, 2026, Pages 81-89]
Endoplasmic reticulum - stress Protocatechuic acid mitigates diazinon-induced lung injury in rats through modulation of oxidative stress, inflammatory, Keap-1/Nrf-2/HO-1 and ER stress-mediated apoptotic pathways [Volume 29, Issue 2, 2026, Pages 261-270]
Endoplasmic reticulum-stress Protective efficacy of thymol in testicular ischemia/reperfusion injury in rats: A biochemical and histopathological evaluation [Volume 29, Issue 7, 2026, Pages 1115-1121]
Endothelial nitric oxide - synthase Nerolidol attenuates cardiac hypertrophy and fibrosis in mice: Modulation of collagen type I, apoptotic and endothelial gene expression [Volume 29, Issue 7, 2026, Pages 1100-1106]
Endothelial progenitor cells- (epcs) Comparative evaluation of cell types for endothelialization in cardiovascular tissue engineering [Volume 29, Issue 7, 2026, Pages 979-990]
Energy metabolism Electroacupuncture improves hypoxic stress and energy metabolism to alleviate vascular cognitive impairment through activation of the HIF-1α/p53/NGB signaling pathway in rats [Volume 29, Issue 1, 2026, Pages 34-42]
Energy metabolism Neuroprotective effects of ROCK inhibition on hippocampal energy metabolism in a rat model of metabolic syndrome [Volume 29, Issue 8, 2026, Pages 1286-1295]
Epidermolysis bullosa (EB) Fabrication of a five-layer wound dressing containing chitosan-LL37 peptide for the treatment of EB wounds and deep exudate patients [Volume 29, Issue 8, 2026, Pages 1229-1240]
Epigallocatechin gallate Combined effects of EGCG and retinol on viability and apoptosis-related gene expression in Caco-2 and HCT-116 colon cancer cells [Volume 29, Issue 6, 2026, Pages 909-914]
Epigenetic pharmaceuticals Beyond bioactivity: Chitosan macromolecular coatings on titanium surfaces drive osseointegration and immune suppression through targeted epigenetic regulation [Volume 29, Issue 7, 2026, Pages 1066-1078]
Epilepsy Rosemary (Rosmarinus officinalis L.) and nervous system disorders: New findings on its neuroprotective properties [Volume 29, Issue 2, 2026, Pages 155-180]
Epithelial-mesenchymal - transition (EMT) Modulation of CCL5 and CXCR4 as EMT signaling biomarkers by cold atmospheric plasma and Anti-PD-1 combination therapy in melanoma: Insights from integrated bioinformatics and in vitro and in vivo validation [Volume 29, Issue 7, 2026, Pages 1052-1065]
ER stress 1,25-Dihydroxyvitamin D3 ameliorates neutrophilic asthma through modulation of ERS-NLRP3 inflammasome axis in a mouse model [Volume 29, Issue 3, 2026, Pages 438-445]
ESAT-6 Quercetin improves ESAT-6-induced pleural mesothelial cell fibrosis by activating the NRF2/HO-1 pathway [Volume 29, Issue 5, 2026, Pages 730-735]
Estrogens Comparative effects of estradiol and daidzein on the expression of endometrial cancer-related genes and histopathological parameters in the uterus of ovariectomized rats [Volume 29, Issue 1, 2026, Pages 145-154]
Eugenol Eugenol attenuates paclitaxel-induced cardiotoxicity by modulating autophagy-related markers in rats [Volume 29, Issue 5, 2026, Pages 794-803]
Exercise Rosa damascena in exercise-induced neuroinflammation and recovery: A narrative review bridging traditional medicine and translational sports science [Volume 29, Issue 5, 2026, Pages 641-656]
Exosome Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]
Exosomes The role of exosomes in brain tumors: Mechanisms, diagnosis, and therapeutic prospects [Volume 29, Issue 3, 2026, Pages 313-321]
Exosomes Characterization of exosomes from hypoxia-activated human amniotic membrane mesenchymal stem cells [Volume 29, Issue 4, 2026, Pages 544-557]
Experimental animal model Can monomethyl fumarate and nifedipine reduce ischemia reperfusion injury in rat ovary, and what is the share of oxidative stress-sensitive transcription factors HIF-1a, Nfkb, and Nrf2? [Volume 29, Issue 3, 2026, Pages 446-457]
Extracellular vesicles The role of exosomes in brain tumors: Mechanisms, diagnosis, and therapeutic prospects [Volume 29, Issue 3, 2026, Pages 313-321]
Extracellular vesicles Characterization of exosomes from hypoxia-activated human amniotic membrane mesenchymal stem cells [Volume 29, Issue 4, 2026, Pages 544-557]

F

Factor-β1 An in vivo evaluation of the antifibrotic potential of inulin against bile duct ligation-induced liver fibrosis [Volume 29, Issue 2, 2026, Pages 271-279]
Farnesoid X receptor An in vivo evaluation of the antifibrotic potential of inulin against bile duct ligation-induced liver fibrosis [Volume 29, Issue 2, 2026, Pages 271-279]
Farnesoid X receptor Time-dependent modulation of FXR and Nrf2 signaling in rat models of BDL-induced cholestasis [Volume 29, Issue 7, 2026, Pages 1012-1019]
Fasudil Neuroprotective effects of ROCK inhibition on hippocampal energy metabolism in a rat model of metabolic syndrome [Volume 29, Issue 8, 2026, Pages 1286-1295]
Fetal development Prenatal morphine exposure induces molecular and structural alterations in the developing hippocampus of neonatal rats [Volume 29, Issue 2, 2026, Pages 212-217]
Fibroblast Transforming PRP into a Shelf-Stable therapy: Lyophilization preserves angiogenic and regenerative properties [Volume 29, Issue 5, 2026, Pages 782-793]
Fibrosis Cinnamophilin ameliorates testosterone-induced prostatic hyperplasia and fibrosis by regulating 5α-reductase and TGF-β/Smad signaling pathway [Volume 29, Issue 1, 2026, Pages 121-127]
Fibrosis Quercetin improves ESAT-6-induced pleural mesothelial cell fibrosis by activating the NRF2/HO-1 pathway [Volume 29, Issue 5, 2026, Pages 730-735]
Fibrosis Hepatoprotective effect of hUC-MSC secretome in LPS-induced HepG2 cells [Volume 29, Issue 6, 2026, Pages 901-908]
Fibrosis Sacubitril/Valsartan: Breaking barriers in uterine adhesion and boosting pregnancy outcomes by suppressing inflammation and fibrosis [Volume 29, Issue 7, 2026, Pages 1107-1114]
Fibrosis Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]
Flavonoid content Evaluation of cytotoxic, anti-oxidant, and apoptotic effects of Dysphania botrys extract on B16F10 and MCF-7 cell lines [Volume 29, Issue 1, 2026, Pages 74-80]
Fluoxetine Fluoxetine attenuates UPR-activation, neuroinflammation, and oxidative stress in a nitroglycerin-induced rat model of migraine [Volume 29, Issue 3, 2026, Pages 458-467]
Forsterite Fabrication and analysis of a PVP-carboxymethyl chitosan/forsterite nanocomposite scaffold with stainless steel base via freeze-drying and neural network techniques [Volume 29, Issue 1, 2026, Pages 101-112]
Freeze drying Evaluation of differentiation of the umbilical cord blood-derived mesenchymal stem cells into male germ-line cells in two-dimensional and three-dimensional scaffolds containing naringin [Volume 29, Issue 2, 2026, Pages 249-260]
FXR Amarogentin relieves cholestatic liver injury caused by ANIT in rats by regulating the FXR and Nrf2 pathways [Volume 29, Issue 1, 2026, Pages 65-73]

G

Gallic acid Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats [Volume 29, Issue 4, 2026, Pages 623-633]
Gallic acid Role of gallic acid in sarcopenia in D-galactose-treated mice [Volume 29, Issue 7, 2026, Pages 1035-1042]
Gamma-aminobutyric acid The effect(s) of berberine from Berberis vulgaris L. (Berberidaceae) on treating type 1 diabetes mellitus in streptozotocin-induced diabetic rats [Volume 29, Issue 4, 2026, Pages 613-622]
Gastrins The effect(s) of berberine from Berberis vulgaris L. (Berberidaceae) on treating type 1 diabetes mellitus in streptozotocin-induced diabetic rats [Volume 29, Issue 4, 2026, Pages 613-622]
Gene delivery Smart micro/nanoneedles for gene delivery [Volume 29, Issue 7, 2026, Pages 991-1011]
Gene editing AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery [Volume 29, Issue 6, 2026, Pages 823-843]
Gene expression Loss of neuraminidase 1 inhibits the activation of hepatic stellate cells through TGF-β/Smad3 signaling [Volume 29, Issue 3, 2026, Pages 387-392]
Gene expression regulation Radiotherapy-associated changes in the miR-124/SP1 axis in a rat glioma model [Volume 29, Issue 8, 2026, Pages 1211-1217]
Gene knockout techniques AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery [Volume 29, Issue 6, 2026, Pages 823-843]
Germ cells Evaluation of differentiation of the umbilical cord blood-derived mesenchymal stem cells into male germ-line cells in two-dimensional and three-dimensional scaffolds containing naringin [Volume 29, Issue 2, 2026, Pages 249-260]
Glioblastoma The role of exosomes in brain tumors: Mechanisms, diagnosis, and therapeutic prospects [Volume 29, Issue 3, 2026, Pages 313-321]
Glioblastoma Immunotherapy Antibody therapies in glioblastoma: Overcoming micro-environmental barriers [Volume 29, Issue 3, 2026, Pages 353-377]
Glioma Radiotherapy-associated changes in the miR-124/SP1 axis in a rat glioma model [Volume 29, Issue 8, 2026, Pages 1211-1217]
Glucose transporter (GLUT) Hispidulin: A potential antihyperglycemic and anti-oxidant agent-mechanistic insights into its modulatory effects on PI3K, AKT, mTOR, IRS1, GSK-3β, and GLUT-4 pathways through in vitro and in vivo studies [Volume 29, Issue 2, 2026, Pages 240-248]
Glycyrrhetinic acid 18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats [Volume 29, Issue 1, 2026, Pages 81-89]
GNAL mRNA Effects of glucocorticoid on cardiac chronotropic responsiveness in cirrhotic rats: A possible role for dopamine receptors [Volume 29, Issue 6, 2026, Pages 893-900]

H

H2O2 In vivo assessment of imoxide and diluted vitamin C’s inhibitory effects on cervical cancer in mice [Volume 29, Issue 6, 2026, Pages 971-978]
HCC LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of immune checkpoint proteins in HCC with python analysis [Volume 29, Issue 6, 2026, Pages 935-941]
Health and-disease Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis [Volume 29, Issue 6, 2026, Pages 844-869]
Heart Injuries Eugenol attenuates paclitaxel-induced cardiotoxicity by modulating autophagy-related markers in rats [Volume 29, Issue 5, 2026, Pages 794-803]
Heart rate Cardiovascular effects of ventrolateral periaqueductal gray (vlPAG) AT1 receptors in normotensive and hemorrhagic rats [Volume 29, Issue 2, 2026, Pages 290-301]
Hela Cells Synergistic induction of apoptosis in cancer cells by combined silver nanoparticles and paclitaxel [Volume 29, Issue 4, 2026, Pages 634-640]
Heme oxygenase - 1 Metformin alleviates anti-oxidant and anti-apoptotic effects by regulating the Nrf2/HO-1 signaling pathway in a rat model of testicular ischemia/reperfusion [Volume 29, Issue 3, 2026, Pages 482-487]
Hemorrhage Cardiovascular effects of ventrolateral periaqueductal gray (vlPAG) AT1 receptors in normotensive and hemorrhagic rats [Volume 29, Issue 2, 2026, Pages 290-301]
Hepatic encephalopathies Combining sorafenib and Lactobacillus rhamnosus GG reduces liver fibrosis and hepatic encephalopathy following bile duct ligation in rats [Volume 29, Issue 5, 2026, Pages 752-765]
Hepatic encephalopathy Involvement of SIRT3 downstream targets ANT1, VDAC, CYPD, and Drp1 in a rat model of hepatic encephalopathy: Therapeutic role of thymoquinone [Volume 29, Issue 6, 2026, Pages 952-960]
Hepatic stellate cell Loss of neuraminidase 1 inhibits the activation of hepatic stellate cells through TGF-β/Smad3 signaling [Volume 29, Issue 3, 2026, Pages 387-392]
Hesperidin Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/Caspase-3, and TLR4/NF-κB axis activatione [Volume 29, Issue 6, 2026, Pages 942-951]
Hexamethonium Cardiovascular effects of ventrolateral periaqueductal gray (vlPAG) AT1 receptors in normotensive and hemorrhagic rats [Volume 29, Issue 2, 2026, Pages 290-301]
HIF-1α Electroacupuncture improves hypoxic stress and energy metabolism to alleviate vascular cognitive impairment through activation of the HIF-1α/p53/NGB signaling pathway in rats [Volume 29, Issue 1, 2026, Pages 34-42]
HIF-1α Can monomethyl fumarate and nifedipine reduce ischemia reperfusion injury in rat ovary, and what is the share of oxidative stress-sensitive transcription factors HIF-1a, Nfkb, and Nrf2? [Volume 29, Issue 3, 2026, Pages 446-457]
High-intensity focused-ultrasound Ultrasound medicine in the era of precision theranostics: Mechanisms, molecular strategies, and clinical translation [Volume 29, Issue 4, 2026, Pages 498-521]
HIPK2 HIPK2 protects neurons from oxidative stress and modulates central nervous system responses following traumatic brain injury [Volume 29, Issue 5, 2026, Pages 804-811]
Hippocampus Prenatal morphine exposure induces molecular and structural alterations in the developing hippocampus of neonatal rats [Volume 29, Issue 2, 2026, Pages 212-217]
Hippocampus Pitolisant disrupts memory consolidation and hippocampal synaptic plasticity: Impaired excitability and long-term potentiation in the CA1 area [Volume 29, Issue 3, 2026, Pages 378-386]
Hippocampus Promising therapeutic efficacy of kolaviron against prenatal valproate-induced autism spectrum disorder [Volume 29, Issue 8, 2026, Pages 1202-1210]
Hippocampus metabolic syndrome Neuroprotective effects of ROCK inhibition on hippocampal energy metabolism in a rat model of metabolic syndrome [Volume 29, Issue 8, 2026, Pages 1286-1295]
Histology Mechanistic insights into the protective effects of vitamin E against olanzapine-induced testicular toxicity: The role of microRNAs in oxidative stress and apoptosis [Volume 29, Issue 6, 2026, Pages 883-892]
HMGB1 protein Investigating the protective effect of zinc supplementation on streptozotocin-induced pancreatic beta-cell damage via the HMGB1/TLR2/MAPK pathway [Volume 29, Issue 7, 2026, Pages 1020-1026]
Honey Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD [Volume 29, Issue 2, 2026, Pages 231-239]
HPMCs Quercetin improves ESAT-6-induced pleural mesothelial cell fibrosis by activating the NRF2/HO-1 pathway [Volume 29, Issue 5, 2026, Pages 730-735]
Huanglian Jiedu decoction Huanglian Jiedu decoction ameliorates Alzheimer’s disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes [Volume 29, Issue 6, 2026, Pages 927-934]
Human umbilical vein-endothelial cells (huvecs) Comparative evaluation of cell types for endothelialization in cardiovascular tissue engineering [Volume 29, Issue 7, 2026, Pages 979-990]
HUVECs Transforming PRP into a Shelf-Stable therapy: Lyophilization preserves angiogenic and regenerative properties [Volume 29, Issue 5, 2026, Pages 782-793]
Hyaluronic acid Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [Volume 29, Issue 6, 2026, Pages 870-882]
Hyaluronic acid Development of a hybrid micelle–hydrogel system for topical delivery of doxorubicin to skin cancer cells [Volume 29, Issue 8, 2026, Pages 1184-1194]
Hydatid Cyst Recent advances in the detection and treatment of hydatid cysts by nanomaterial-based carriers [Volume 29, Issue 5, 2026, Pages 657-674]
Hydrogel Therapeutic potential of a pullulan polysaccharide-based hydrogel with antibacterial peptide for skin wound healing [Volume 29, Issue 3, 2026, Pages 412-422]
Hydrogel Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]
Hydrogel Development of a hybrid micelle–hydrogel system for topical delivery of doxorubicin to skin cancer cells [Volume 29, Issue 8, 2026, Pages 1184-1194]
Hydrogen peroxide In vivo assessment of imoxide and diluted vitamin C’s inhibitory effects on cervical cancer in mice [Volume 29, Issue 6, 2026, Pages 971-978]
Hyperbranched - polyglycerol Synthesis, radiolabeling, and biodistribution evaluation of novel hyperbranched polyglycerols-based radiotracers for targeting PSMA in prostate cancer [Volume 29, Issue 7, 2026, Pages 1089-1099]
Hypertension Ashwagandha (Withania somnifera) in insulin resistance and metabolic syndrome: A literature review on mechanisms [Volume 29, Issue 1, 2026, Pages 3-21]
Hypertensive nephropathy Norepinephrine promotes the proliferation, migration, and phenotypic transformation of renal artery vascular smooth muscle cells via ROCK1 [Volume 29, Issue 4, 2026, Pages 605-612]
Hypoglycaemic effect Hispidulin: A potential antihyperglycemic and anti-oxidant agent-mechanistic insights into its modulatory effects on PI3K, AKT, mTOR, IRS1, GSK-3β, and GLUT-4 pathways through in vitro and in vivo studies [Volume 29, Issue 2, 2026, Pages 240-248]
Hypoxia Hypoxic tumor microenvironment and immune cell dynamics: From metabolic reprogramming to therapeutic innovation [Volume 29, Issue 3, 2026, Pages 334-352]
Hypoxia Characterization of exosomes from hypoxia-activated human amniotic membrane mesenchymal stem cells [Volume 29, Issue 4, 2026, Pages 544-557]
Hypoxic stress Electroacupuncture improves hypoxic stress and energy metabolism to alleviate vascular cognitive impairment through activation of the HIF-1α/p53/NGB signaling pathway in rats [Volume 29, Issue 1, 2026, Pages 34-42]

I

Immune cells Hypoxic tumor microenvironment and immune cell dynamics: From metabolic reprogramming to therapeutic innovation [Volume 29, Issue 3, 2026, Pages 334-352]
Immune checkpoint - proteins LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of immune checkpoint proteins in HCC with python analysis [Volume 29, Issue 6, 2026, Pages 935-941]
Immune evasion Non-coding RNAs related to PD1/PD-L1 signaling with potential diagnostic, prognostic, and therapeutic value in the tumorigenesis of brain cancers [Volume 29, Issue 8, 2026, Pages 1174-1183]
Immune tolerance Phenotypic alterations in the immune system and tolerance induction in tumor-draining lymph nodes [Volume 29, Issue 4, 2026, Pages 488-497]
Immunometabolism Hypoxic tumor microenvironment and immune cell dynamics: From metabolic reprogramming to therapeutic innovation [Volume 29, Issue 3, 2026, Pages 334-352]
Immunotherapy Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer [Volume 29, Issue 5, 2026, Pages 688-716]
Imoxide In vivo assessment of imoxide and diluted vitamin C’s inhibitory effects on cervical cancer in mice [Volume 29, Issue 6, 2026, Pages 971-978]
Indian ginseng Ashwagandha (Withania somnifera) in insulin resistance and metabolic syndrome: A literature review on mechanisms [Volume 29, Issue 1, 2026, Pages 3-21]
Induced pluripotent stem cells (ipscs) Comparative evaluation of cell types for endothelialization in cardiovascular tissue engineering [Volume 29, Issue 7, 2026, Pages 979-990]
Infertility The role of oxidative stress in sleep deprivation-induced reproductive dysfunction: A rationale for anti-oxidant intervention [Volume 29, Issue 2, 2026, Pages 191-201]
Infertility Sacubitril/Valsartan: Breaking barriers in uterine adhesion and boosting pregnancy outcomes by suppressing inflammation and fibrosis [Volume 29, Issue 7, 2026, Pages 1107-1114]
Inflammasomes Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity [Volume 29, Issue 1, 2026, Pages 90-100]
Inflammation Neuroprotective effects of kojic acid and nano-kojic acid in experimental brain ischemia induced by bilateral common carotid artery occlusion [Volume 29, Issue 1, 2026, Pages 43-54]
Inflammation Raspberry protective role in inflammatory diseases: An overview [Volume 29, Issue 1, 2026, Pages 22-33]
Inflammation Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD [Volume 29, Issue 2, 2026, Pages 231-239]
Inflammation Protocatechuic acid mitigates diazinon-induced lung injury in rats through modulation of oxidative stress, inflammatory, Keap-1/Nrf-2/HO-1 and ER stress-mediated apoptotic pathways [Volume 29, Issue 2, 2026, Pages 261-270]
Inflammation Syringic acid attenuates LPS-induced acute lung injury via modulation of the HMGB1/TLR4/NF-κB and Keap1/Nrf2/HO-1 pathways: Mechanistic insights from in vivo and in silico studies [Volume 29, Issue 2, 2026, Pages 302-312]
Inflammation Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats [Volume 29, Issue 4, 2026, Pages 623-633]
Inflammation Mitigation of sepsis-associated acute kidney injury by thymoquinone via targeting pyroptosis and attenuation of inflammation in C57BL/6 mice [Volume 29, Issue 5, 2026, Pages 717-723]
Inflammation Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/Caspase-3, and TLR4/NF-κB axis activatione [Volume 29, Issue 6, 2026, Pages 942-951]
Inflammation Hepatoprotective effect of hUC-MSC secretome in LPS-induced HepG2 cells [Volume 29, Issue 6, 2026, Pages 901-908]
Inflammation Protective efficacy of thymol in testicular ischemia/reperfusion injury in rats: A biochemical and histopathological evaluation [Volume 29, Issue 7, 2026, Pages 1115-1121]
Inflammation Sacubitril/Valsartan: Breaking barriers in uterine adhesion and boosting pregnancy outcomes by suppressing inflammation and fibrosis [Volume 29, Issue 7, 2026, Pages 1107-1114]
Inflammation Ponicidin alleviates atherosclerosis by inhibiting inflammation and oxidative stress through the SIRT1 and PI3K/Akt pathway [Volume 29, Issue 8, 2026, Pages 1195-1201]
Inflammatory response Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity [Volume 29, Issue 1, 2026, Pages 90-100]
Injectable hydrogel An in-depth examination of bone avascular necrosis and early-stage treatment modalities utilizing regenerative medicine [Volume 29, Issue 8, 2026, Pages 1131-1153]
INOS Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling [Volume 29, Issue 3, 2026, Pages 423-437]
Intranasal delivery Cannabidiol: Pharmaceutical formulations and biomedical applications [Volume 29, Issue 4, 2026, Pages 522-530]
Inulin An in vivo evaluation of the antifibrotic potential of inulin against bile duct ligation-induced liver fibrosis [Volume 29, Issue 2, 2026, Pages 271-279]
Iron oxide nanoparticles Bioinformatic analysis and characterization of the Anti-CD20 scFv-Conjugated Fe₃O₄ nanoparticles for targeted therapy of CD20⁺ leukemia cells [Volume 29, Issue 8, 2026, Pages 1259-1268]
Ischemia Neuroprotective effects of kojic acid and nano-kojic acid in experimental brain ischemia induced by bilateral common carotid artery occlusion [Volume 29, Issue 1, 2026, Pages 43-54]
Ischemia Cannabidiol attenuates lung ischemia-reperfusion injury by modulating RIPK1/RIPK3-mediated necroptosis and HIF-1α/VEGF signaling [Volume 29, Issue 5, 2026, Pages 766-773]
Ischemia/Reperfusion Dexmedetomidine protects against ischemia and reperfusion-induced kidney injury in rats by inhibiting the expression of TRPM2 and TRPA1 channels [Volume 29, Issue 4, 2026, Pages 590-597]
Ischemia-reperfusion injury Can monomethyl fumarate and nifedipine reduce ischemia reperfusion injury in rat ovary, and what is the share of oxidative stress-sensitive transcription factors HIF-1a, Nfkb, and Nrf2? [Volume 29, Issue 3, 2026, Pages 446-457]
Ischemia reperfusion injury Kelch-Like ECH-associated- protein 1 Metformin alleviates anti-oxidant and anti-apoptotic effects by regulating the Nrf2/HO-1 signaling pathway in a rat model of testicular ischemia/reperfusion [Volume 29, Issue 3, 2026, Pages 482-487]
Islets of Langerhans The effect(s) of berberine from Berberis vulgaris L. (Berberidaceae) on treating type 1 diabetes mellitus in streptozotocin-induced diabetic rats [Volume 29, Issue 4, 2026, Pages 613-622]
Isoproterenol Nerolidol attenuates cardiac hypertrophy and fibrosis in mice: Modulation of collagen type I, apoptotic and endothelial gene expression [Volume 29, Issue 7, 2026, Pages 1100-1106]

L

Lactobacillus Rhamnosus Combining sorafenib and Lactobacillus rhamnosus GG reduces liver fibrosis and hepatic encephalopathy following bile duct ligation in rats [Volume 29, Issue 5, 2026, Pages 752-765]
Limonin Compromised blood-brain barrier in traumatic brain injury model of Danio rerio: A unique window to demonstrate restoration of behavioral, cellular, and neurochemical deficits by limonin [Volume 29, Issue 3, 2026, Pages 468-481]
Lipid nanoparticles A review on recent advances in lipid-based drug delivery systems for tuberculosis [Volume 29, Issue 3, 2026, Pages 322-333]
Lipid nanoparticles Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey [Volume 29, Issue 6, 2026, Pages 812-822]
Lipopolysaccharide Syringic acid attenuates LPS-induced acute lung injury via modulation of the HMGB1/TLR4/NF-κB and Keap1/Nrf2/HO-1 pathways: Mechanistic insights from in vivo and in silico studies [Volume 29, Issue 2, 2026, Pages 302-312]
Lipopolysaccharide Mitigation of sepsis-associated acute kidney injury by thymoquinone via targeting pyroptosis and attenuation of inflammation in C57BL/6 mice [Volume 29, Issue 5, 2026, Pages 717-723]
Lipopolysaccharides Investigating the effects of taurine on Aβ-degradation proteins and neurogenesis-related genes in an LPS-induced neuroinflammatory SH-SY5Y cell model [Volume 29, Issue 7, 2026, Pages 1043-1051]
Liposomes A review on recent advances in lipid-based drug delivery systems for tuberculosis [Volume 29, Issue 3, 2026, Pages 322-333]
Liver fibrosis Loss of neuraminidase 1 inhibits the activation of hepatic stellate cells through TGF-β/Smad3 signaling [Volume 29, Issue 3, 2026, Pages 387-392]
Liver fibrosis An in vivo evaluation of the antifibrotic potential of inulin against bile duct ligation-induced liver fibrosis [Volume 29, Issue 2, 2026, Pages 271-279]
Liver fibrosis Combining sorafenib and Lactobacillus rhamnosus GG reduces liver fibrosis and hepatic encephalopathy following bile duct ligation in rats [Volume 29, Issue 5, 2026, Pages 752-765]
LKB1 LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of immune checkpoint proteins in HCC with python analysis [Volume 29, Issue 6, 2026, Pages 935-941]
Local EEG Involvement of SIRT3 downstream targets ANT1, VDAC, CYPD, and Drp1 in a rat model of hepatic encephalopathy: Therapeutic role of thymoquinone [Volume 29, Issue 6, 2026, Pages 952-960]
Long non-coding Comparison of long non-coding RNA NEAT1 expression, P53, and antioxidant factors between Alzheimer’s patients and healthy individuals [Volume 29, Issue 4, 2026, Pages 598-604]
Long non-coding RNA CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease [Volume 29, Issue 6, 2026, Pages 915-926]
Long-term potentiation Pitolisant disrupts memory consolidation and hippocampal synaptic plasticity: Impaired excitability and long-term potentiation in the CA1 area [Volume 29, Issue 3, 2026, Pages 378-386]
Losartan Cardiovascular effects of ventrolateral periaqueductal gray (vlPAG) AT1 receptors in normotensive and hemorrhagic rats [Volume 29, Issue 2, 2026, Pages 290-301]
Low-intensity pulsed-ultrasound Ultrasound medicine in the era of precision theranostics: Mechanisms, molecular strategies, and clinical translation [Volume 29, Issue 4, 2026, Pages 498-521]
Lung injury Cannabidiol attenuates lung ischemia-reperfusion injury by modulating RIPK1/RIPK3-mediated necroptosis and HIF-1α/VEGF signaling [Volume 29, Issue 5, 2026, Pages 766-773]
Lupus nephritis The protective effect of resveratrol on lupus nephritis mice by up-regulating Sirt1 [Volume 29, Issue 1, 2026, Pages 138-144]
Lyophilization Transforming PRP into a Shelf-Stable therapy: Lyophilization preserves angiogenic and regenerative properties [Volume 29, Issue 5, 2026, Pages 782-793]

M

Matrix metalloproteinase 9 Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD [Volume 29, Issue 2, 2026, Pages 231-239]
Matrix metalloproteinase 9 Investigating the effects of taurine on Aβ-degradation proteins and neurogenesis-related genes in an LPS-induced neuroinflammatory SH-SY5Y cell model [Volume 29, Issue 7, 2026, Pages 1043-1051]
Mechanism Amarogentin relieves cholestatic liver injury caused by ANIT in rats by regulating the FXR and Nrf2 pathways [Volume 29, Issue 1, 2026, Pages 65-73]
Mechanistic target of - rapamycin complex 1 Eugenol attenuates paclitaxel-induced cardiotoxicity by modulating autophagy-related markers in rats [Volume 29, Issue 5, 2026, Pages 794-803]
Melanoma Modulation of CCL5 and CXCR4 as EMT signaling biomarkers by cold atmospheric plasma and Anti-PD-1 combination therapy in melanoma: Insights from integrated bioinformatics and in vitro and in vivo validation [Volume 29, Issue 7, 2026, Pages 1052-1065]
Memory consolidation Pitolisant disrupts memory consolidation and hippocampal synaptic plasticity: Impaired excitability and long-term potentiation in the CA1 area [Volume 29, Issue 3, 2026, Pages 378-386]
Mesenchymal stem cells Conditioned medium from mesenchymal stem cells: Towards skin tissue engineering and wound healing [Volume 29, Issue 2, 2026, Pages 181-190]
Mesenchymal stem cells Evaluation of differentiation of the umbilical cord blood-derived mesenchymal stem cells into male germ-line cells in two-dimensional and three-dimensional scaffolds containing naringin [Volume 29, Issue 2, 2026, Pages 249-260]
Mesenchymal stem cells Characterization of exosomes from hypoxia-activated human amniotic membrane mesenchymal stem cells [Volume 29, Issue 4, 2026, Pages 544-557]
Mesenchymal stem cells- (mscs) Comparative evaluation of cell types for endothelialization in cardiovascular tissue engineering [Volume 29, Issue 7, 2026, Pages 979-990]
Metformin Metformin alleviates anti-oxidant and anti-apoptotic effects by regulating the Nrf2/HO-1 signaling pathway in a rat model of testicular ischemia/reperfusion [Volume 29, Issue 3, 2026, Pages 482-487]
Mice Inhibition of the PKC-TRPV1-SP axis by propolis ameliorates chronic inflammatory pain in mice [Volume 29, Issue 5, 2026, Pages 744-751]
Micelles An in vivo study on sonodynamic effects mediated by nanomicelles containing PpIX as a sonosensitizing agent [Volume 29, Issue 2, 2026, Pages 225-230]
Microglial cell Compromised blood-brain barrier in traumatic brain injury model of Danio rerio: A unique window to demonstrate restoration of behavioral, cellular, and neurochemical deficits by limonin [Volume 29, Issue 3, 2026, Pages 468-481]
Microneedle Smart micro/nanoneedles for gene delivery [Volume 29, Issue 7, 2026, Pages 991-1011]
MicroRNA Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis [Volume 29, Issue 6, 2026, Pages 844-869]
MicroRNA modulatory Mechanistic insights into the protective effects of vitamin E against olanzapine-induced testicular toxicity: The role of microRNAs in oxidative stress and apoptosis [Volume 29, Issue 6, 2026, Pages 883-892]
Migraine disorders Fluoxetine attenuates UPR-activation, neuroinflammation, and oxidative stress in a nitroglycerin-induced rat model of migraine [Volume 29, Issue 3, 2026, Pages 458-467]
Minocycline Effects of minocycline on acrylamide-induced neurotoxicity in Wistar rats [Volume 29, Issue 3, 2026, Pages 393-400]
MIRI Remote ischemic preconditioning protects heart via modulation of purinergic signaling and AMPK-mediated autophagy in rat model of ischemia reperfusion injury [Volume 29, Issue 4, 2026, Pages 558-569]
Mitochondria-associated- membranes (MAMs) Huanglian Jiedu decoction ameliorates Alzheimer’s disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes [Volume 29, Issue 6, 2026, Pages 927-934]
Mitochondrial fission Norepinephrine promotes the proliferation, migration, and phenotypic transformation of renal artery vascular smooth muscle cells via ROCK1 [Volume 29, Issue 4, 2026, Pages 605-612]
Mitochondrion Role of gallic acid in sarcopenia in D-galactose-treated mice [Volume 29, Issue 7, 2026, Pages 1035-1042]
Mitogen-activated protein kinases/Extracellular signal-regulated kinases Impact of TGF-β and ERK1/2 inhibition on preimplantation embryo development and quality [Volume 29, Issue 4, 2026, Pages 578-589]
Molecular docking Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats [Volume 29, Issue 4, 2026, Pages 623-633]
Molecular docking Bioinformatic analysis and characterization of the Anti-CD20 scFv-Conjugated Fe₃O₄ nanoparticles for targeted therapy of CD20⁺ leukemia cells [Volume 29, Issue 8, 2026, Pages 1259-1268]
Molecular dynamics - Simulation Comparative analysis of second and third-generation nanobody-based CAR-NK cells targeting PSMA in prostate cancer immunotherapy: In silico and in vitro studies [Volume 29, Issue 7, 2026, Pages 1122-1130]
Molecular imaging Ultrasound medicine in the era of precision theranostics: Mechanisms, molecular strategies, and clinical translation [Volume 29, Issue 4, 2026, Pages 498-521]
Molecular imaging Synthesis, radiolabeling, and biodistribution evaluation of novel hyperbranched polyglycerols-based radiotracers for targeting PSMA in prostate cancer [Volume 29, Issue 7, 2026, Pages 1089-1099]
Molecular mechanism Kurarinone: From chemistry to pharmacological values–A review [Volume 29, Issue 5, 2026, Pages 675-687]
Molecular Pathways Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis [Volume 29, Issue 6, 2026, Pages 844-869]
Molecular targeted therapy Hypoxic tumor microenvironment and immune cell dynamics: From metabolic reprogramming to therapeutic innovation [Volume 29, Issue 3, 2026, Pages 334-352]
Morphine Prenatal morphine exposure induces molecular and structural alterations in the developing hippocampus of neonatal rats [Volume 29, Issue 2, 2026, Pages 212-217]
Mouth neoplasms NF-kappa B Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [Volume 29, Issue 6, 2026, Pages 870-882]
Multiple Sclerosis Synergistic myelin regenerative, immunomodulatory and anti-inflammatory effects of vanillin and adipose derived stem cells in cuprizone animal model of multiple sclerosis [Volume 29, Issue 7, 2026, Pages 1027-1034]
Muscle regeneration Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]
Musculoskeletal ultrasound Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]
Myelin Synergistic myelin regenerative, immunomodulatory and anti-inflammatory effects of vanillin and adipose derived stem cells in cuprizone animal model of multiple sclerosis [Volume 29, Issue 7, 2026, Pages 1027-1034]
Myocardial reperfusion injury Delta opioid peptide (D-Ala2, D-Leu5)-enkephalin (DADLE) mitigates myocardial ischemia-reperfusion injury by inhibiting the TRAF6/NF-κB/NLRP3 pathway [Volume 29, Issue 2, 2026, Pages 218-224]

N

Nanocarriers Recent advances in the detection and treatment of hydatid cysts by nanomaterial-based carriers [Volume 29, Issue 5, 2026, Pages 657-674]
Nanofibers Evaluation of differentiation of the umbilical cord blood-derived mesenchymal stem cells into male germ-line cells in two-dimensional and three-dimensional scaffolds containing naringin [Volume 29, Issue 2, 2026, Pages 249-260]
Nanomedicine Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey [Volume 29, Issue 6, 2026, Pages 812-822]
Nanoneedle Smart micro/nanoneedles for gene delivery [Volume 29, Issue 7, 2026, Pages 991-1011]
Nanoparticle Recent advances in the detection and treatment of hydatid cysts by nanomaterial-based carriers [Volume 29, Issue 5, 2026, Pages 657-674]
Nanoparticles A review on recent advances in lipid-based drug delivery systems for tuberculosis [Volume 29, Issue 3, 2026, Pages 322-333]
Nanoparticles Fabrication and analysis of a PVP-carboxymethyl chitosan/forsterite nanocomposite scaffold with stainless steel base via freeze-drying and neural network techniques [Volume 29, Issue 1, 2026, Pages 101-112]
Nanoparticles An in vivo study on sonodynamic effects mediated by nanomicelles containing PpIX as a sonosensitizing agent [Volume 29, Issue 2, 2026, Pages 225-230]
Nanoparticles Synergistic induction of apoptosis in cancer cells by combined silver nanoparticles and paclitaxel [Volume 29, Issue 4, 2026, Pages 634-640]
Nanotechnology Cannabidiol: Pharmaceutical formulations and biomedical applications [Volume 29, Issue 4, 2026, Pages 522-530]
Nasal delivery Improved bioavailability of raloxifene hydrochloride through nasal administration of poly (methyl vinyl ether-co-maleic acid) nanoparticles in ovariectomized rats [Volume 29, Issue 2, 2026, Pages 202-211]
Natural killer cell Comparative analysis of second and third-generation nanobody-based CAR-NK cells targeting PSMA in prostate cancer immunotherapy: In silico and in vitro studies [Volume 29, Issue 7, 2026, Pages 1122-1130]
NEAT1 Comparison of long non-coding RNA NEAT1 expression, P53, and antioxidant factors between Alzheimer’s patients and healthy individuals [Volume 29, Issue 4, 2026, Pages 598-604]
NEAT1 CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease [Volume 29, Issue 6, 2026, Pages 915-926]
Necroptosis Cannabidiol attenuates lung ischemia-reperfusion injury by modulating RIPK1/RIPK3-mediated necroptosis and HIF-1α/VEGF signaling [Volume 29, Issue 5, 2026, Pages 766-773]
Necroptosis Cordycepin ameliorates ischemia/reperfusion-induced acute kidney injury via inhibiting apoptosis and necroptosis [Volume 29, Issue 8, 2026, Pages 1218-1228]
Neoplasm dormancy AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery [Volume 29, Issue 6, 2026, Pages 823-843]
Neoplasm metastasis Phenotypic alterations in the immune system and tolerance induction in tumor-draining lymph nodes [Volume 29, Issue 4, 2026, Pages 488-497]
Nephrotoxicity Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats [Volume 29, Issue 4, 2026, Pages 623-633]
Nerolidol Nerolidol attenuates cardiac hypertrophy and fibrosis in mice: Modulation of collagen type I, apoptotic and endothelial gene expression [Volume 29, Issue 7, 2026, Pages 1100-1106]
Neuraminidase Loss of neuraminidase 1 inhibits the activation of hepatic stellate cells through TGF-β/Smad3 signaling [Volume 29, Issue 3, 2026, Pages 387-392]
Neurogenesis Resveratrol mitigates diazinon-induced neurotoxicity during fetal brain development [Volume 29, Issue 8, 2026, Pages 1249-1258]
Neurogenesis Neuroinflammatory - diseases Investigating the effects of taurine on Aβ-degradation proteins and neurogenesis-related genes in an LPS-induced neuroinflammatory SH-SY5Y cell model [Volume 29, Issue 7, 2026, Pages 1043-1051]
Neuroinflammation Raspberry protective role in inflammatory diseases: An overview [Volume 29, Issue 1, 2026, Pages 22-33]
Neuroinflammation 18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats [Volume 29, Issue 1, 2026, Pages 81-89]
Neuroinflammation The effect of tert-butylhydroquinone on anxiolytic- and antidepressant-like behaviors induced by post-traumatic stress disorder: A behavioral and molecular study [Volume 29, Issue 1, 2026, Pages 113-120]
Neuroinflammation Rosa damascena in exercise-induced neuroinflammation and recovery: A narrative review bridging traditional medicine and translational sports science [Volume 29, Issue 5, 2026, Pages 641-656]
Neuroinflammation Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis [Volume 29, Issue 6, 2026, Pages 844-869]
Neuroinflammation Trigonelline protects against alcohol-induced brain damage by inhibition of oxidative stress, TLR4/NF-κB/proinflammatory cytokines pathway, and apoptosis [Volume 29, Issue 7, 2026, Pages 1079-1088]
Neuroprotection Neuroprotective effects of kojic acid and nano-kojic acid in experimental brain ischemia induced by bilateral common carotid artery occlusion [Volume 29, Issue 1, 2026, Pages 43-54]
Neuroprotection Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling [Volume 29, Issue 3, 2026, Pages 423-437]
Neuroprotection HIPK2 protects neurons from oxidative stress and modulates central nervous system responses following traumatic brain injury [Volume 29, Issue 5, 2026, Pages 804-811]
Neuroprotection Neuroprotective effects of ROCK inhibition on hippocampal energy metabolism in a rat model of metabolic syndrome [Volume 29, Issue 8, 2026, Pages 1286-1295]
Neuroprotective agents Investigation of neuroprotective and antiapoptotic effects of rosmarinic acid in an in vitro Alzheimer’s disease model [Volume 29, Issue 8, 2026, Pages 1241-1248]
Neuroprotective agents Taurine Investigating the effects of taurine on Aβ-degradation proteins and neurogenesis-related genes in an LPS-induced neuroinflammatory SH-SY5Y cell model [Volume 29, Issue 7, 2026, Pages 1043-1051]
Neurotoxicity Effects of minocycline on acrylamide-induced neurotoxicity in Wistar rats [Volume 29, Issue 3, 2026, Pages 393-400]
Neurotoxicity Trigonelline protects against alcohol-induced brain damage by inhibition of oxidative stress, TLR4/NF-κB/proinflammatory cytokines pathway, and apoptosis [Volume 29, Issue 7, 2026, Pages 1079-1088]
Neurotoxicity Resveratrol mitigates diazinon-induced neurotoxicity during fetal brain development [Volume 29, Issue 8, 2026, Pages 1249-1258]
Neurotoxicity Syndromes Prenatal morphine exposure induces molecular and structural alterations in the developing hippocampus of neonatal rats [Volume 29, Issue 2, 2026, Pages 212-217]
Neutrophilic asthma 1,25-Dihydroxyvitamin D3 ameliorates neutrophilic asthma through modulation of ERS-NLRP3 inflammasome axis in a mouse model [Volume 29, Issue 3, 2026, Pages 438-445]
Newborn Prenatal morphine exposure induces molecular and structural alterations in the developing hippocampus of neonatal rats [Volume 29, Issue 2, 2026, Pages 212-217]
NF-E2-related factor 2 Metformin alleviates anti-oxidant and anti-apoptotic effects by regulating the Nrf2/HO-1 signaling pathway in a rat model of testicular ischemia/reperfusion [Volume 29, Issue 3, 2026, Pages 482-487]
NF-kappa B Delta opioid peptide (D-Ala2, D-Leu5)-enkephalin (DADLE) mitigates myocardial ischemia-reperfusion injury by inhibiting the TRAF6/NF-κB/NLRP3 pathway [Volume 29, Issue 2, 2026, Pages 218-224]
NF-kappa B Syringic acid attenuates LPS-induced acute lung injury via modulation of the HMGB1/TLR4/NF-κB and Keap1/Nrf2/HO-1 pathways: Mechanistic insights from in vivo and in silico studies [Volume 29, Issue 2, 2026, Pages 302-312]
NF-κB Can monomethyl fumarate and nifedipine reduce ischemia reperfusion injury in rat ovary, and what is the share of oxidative stress-sensitive transcription factors HIF-1a, Nfkb, and Nrf2? [Volume 29, Issue 3, 2026, Pages 446-457]
Nicotinamide Hispidulin: A potential antihyperglycemic and anti-oxidant agent-mechanistic insights into its modulatory effects on PI3K, AKT, mTOR, IRS1, GSK-3β, and GLUT-4 pathways through in vitro and in vivo studies [Volume 29, Issue 2, 2026, Pages 240-248]
Nitroglycerin Fluoxetine attenuates UPR-activation, neuroinflammation, and oxidative stress in a nitroglycerin-induced rat model of migraine [Volume 29, Issue 3, 2026, Pages 458-467]
NLRP3 inflammasome 1,25-Dihydroxyvitamin D3 ameliorates neutrophilic asthma through modulation of ERS-NLRP3 inflammasome axis in a mouse model [Volume 29, Issue 3, 2026, Pages 438-445]
NLRP3 protein Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity [Volume 29, Issue 1, 2026, Pages 90-100]
NLRP3 protein Delta opioid peptide (D-Ala2, D-Leu5)-enkephalin (DADLE) mitigates myocardial ischemia-reperfusion injury by inhibiting the TRAF6/NF-κB/NLRP3 pathway [Volume 29, Issue 2, 2026, Pages 218-224]
Non-coding RNAs Non-coding RNAs related to PD1/PD-L1 signaling with potential diagnostic, prognostic, and therapeutic value in the tumorigenesis of brain cancers [Volume 29, Issue 8, 2026, Pages 1174-1183]
Non-Small-Cell Lung Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer [Volume 29, Issue 5, 2026, Pages 688-716]
Norepinephrine Norepinephrine promotes the proliferation, migration, and phenotypic transformation of renal artery vascular smooth muscle cells via ROCK1 [Volume 29, Issue 4, 2026, Pages 605-612]
Nrf2 Amarogentin relieves cholestatic liver injury caused by ANIT in rats by regulating the FXR and Nrf2 pathways [Volume 29, Issue 1, 2026, Pages 65-73]
Nrf2 Can monomethyl fumarate and nifedipine reduce ischemia reperfusion injury in rat ovary, and what is the share of oxidative stress-sensitive transcription factors HIF-1a, Nfkb, and Nrf2? [Volume 29, Issue 3, 2026, Pages 446-457]
Nrf2/HO-1 Quercetin improves ESAT-6-induced pleural mesothelial cell fibrosis by activating the NRF2/HO-1 pathway [Volume 29, Issue 5, 2026, Pages 730-735]
Nuclear factor erythroid 2-related factor 2 Time-dependent modulation of FXR and Nrf2 signaling in rat models of BDL-induced cholestasis [Volume 29, Issue 7, 2026, Pages 1012-1019]

O

Olanzapine Mechanistic insights into the protective effects of vitamin E against olanzapine-induced testicular toxicity: The role of microRNAs in oxidative stress and apoptosis [Volume 29, Issue 6, 2026, Pages 883-892]
Oligodendrocyte Synergistic myelin regenerative, immunomodulatory and anti-inflammatory effects of vanillin and adipose derived stem cells in cuprizone animal model of multiple sclerosis [Volume 29, Issue 7, 2026, Pages 1027-1034]
Opioid Delta opioid peptide (D-Ala2, D-Leu5)-enkephalin (DADLE) mitigates myocardial ischemia-reperfusion injury by inhibiting the TRAF6/NF-κB/NLRP3 pathway [Volume 29, Issue 2, 2026, Pages 218-224]
Oral delivery Cannabidiol: Pharmaceutical formulations and biomedical applications [Volume 29, Issue 4, 2026, Pages 522-530]
Origanum Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD [Volume 29, Issue 2, 2026, Pages 231-239]
Osteoconductive Enhanced bone regeneration and cellular protection from oxidative stress using a vitamin C-based scaffold [Volume 29, Issue 2, 2026, Pages 280-289]
Osteogenesis Preparation and characterization of decellularized bovine bone as a bioscaffold for bone tissue engineering applications [Volume 29, Issue 1, 2026, Pages 128-137]
Osteogenic processes Beyond bioactivity: Chitosan macromolecular coatings on titanium surfaces drive osseointegration and immune suppression through targeted epigenetic regulation [Volume 29, Issue 7, 2026, Pages 1066-1078]
Osteoinductive Enhanced bone regeneration and cellular protection from oxidative stress using a vitamin C-based scaffold [Volume 29, Issue 2, 2026, Pages 280-289]
Osteonecrosis An in-depth examination of bone avascular necrosis and early-stage treatment modalities utilizing regenerative medicine [Volume 29, Issue 8, 2026, Pages 1131-1153]
Osteoporosis Protective effects and mechanism of chrysophanol against age-related osteoporosis in rats [Volume 29, Issue 5, 2026, Pages 724-729]
Ovariectomized rats Improved bioavailability of raloxifene hydrochloride through nasal administration of poly (methyl vinyl ether-co-maleic acid) nanoparticles in ovariectomized rats [Volume 29, Issue 2, 2026, Pages 202-211]
Ovariectomy Comparative effects of estradiol and daidzein on the expression of endometrial cancer-related genes and histopathological parameters in the uterus of ovariectomized rats [Volume 29, Issue 1, 2026, Pages 145-154]
OX40 co-stimulatory domain Comparative analysis of second and third-generation nanobody-based CAR-NK cells targeting PSMA in prostate cancer immunotherapy: In silico and in vitro studies [Volume 29, Issue 7, 2026, Pages 1122-1130]
Oxadiazole Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling [Volume 29, Issue 3, 2026, Pages 423-437]
Oxidative stress Neuroprotective effects of kojic acid and nano-kojic acid in experimental brain ischemia induced by bilateral common carotid artery occlusion [Volume 29, Issue 1, 2026, Pages 43-54]
Oxidative stress 18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats [Volume 29, Issue 1, 2026, Pages 81-89]
Oxidative stress The protective effect of resveratrol on lupus nephritis mice by up-regulating Sirt1 [Volume 29, Issue 1, 2026, Pages 138-144]
Oxidative stress Comparative effects of estradiol and daidzein on the expression of endometrial cancer-related genes and histopathological parameters in the uterus of ovariectomized rats [Volume 29, Issue 1, 2026, Pages 145-154]
Oxidative stress The role of oxidative stress in sleep deprivation-induced reproductive dysfunction: A rationale for anti-oxidant intervention [Volume 29, Issue 2, 2026, Pages 191-201]
Oxidative stress Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD [Volume 29, Issue 2, 2026, Pages 231-239]
Oxidative stress Syringic acid attenuates LPS-induced acute lung injury via modulation of the HMGB1/TLR4/NF-κB and Keap1/Nrf2/HO-1 pathways: Mechanistic insights from in vivo and in silico studies [Volume 29, Issue 2, 2026, Pages 302-312]
Oxidative stress In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3 [Volume 29, Issue 3, 2026, Pages 401-411]
Oxidative stress Effects of minocycline on acrylamide-induced neurotoxicity in Wistar rats [Volume 29, Issue 3, 2026, Pages 393-400]
Oxidative stress Fluoxetine attenuates UPR-activation, neuroinflammation, and oxidative stress in a nitroglycerin-induced rat model of migraine [Volume 29, Issue 3, 2026, Pages 458-467]
Oxidative stress Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling [Volume 29, Issue 3, 2026, Pages 423-437]
Oxidative stress Trans sodium crocetinate protects against hepatotoxicity induced by bisphenol A in rats [Volume 29, Issue 4, 2026, Pages 570-577]
Oxidative stress Can monomethyl fumarate and nifedipine reduce ischemia reperfusion injury in rat ovary, and what is the share of oxidative stress-sensitive transcription factors HIF-1a, Nfkb, and Nrf2? [Volume 29, Issue 3, 2026, Pages 446-457]
Oxidative stress Comparison of long non-coding RNA NEAT1 expression, P53, and antioxidant factors between Alzheimer’s patients and healthy individuals [Volume 29, Issue 4, 2026, Pages 598-604]
Oxidative stress Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats [Volume 29, Issue 4, 2026, Pages 623-633]
Oxidative stress Rosa damascena in exercise-induced neuroinflammation and recovery: A narrative review bridging traditional medicine and translational sports science [Volume 29, Issue 5, 2026, Pages 641-656]
Oxidative stress HIPK2 protects neurons from oxidative stress and modulates central nervous system responses following traumatic brain injury [Volume 29, Issue 5, 2026, Pages 804-811]
Oxidative stress Eugenol attenuates paclitaxel-induced cardiotoxicity by modulating autophagy-related markers in rats [Volume 29, Issue 5, 2026, Pages 794-803]
Oxidative stress Mitigation of sepsis-associated acute kidney injury by thymoquinone via targeting pyroptosis and attenuation of inflammation in C57BL/6 mice [Volume 29, Issue 5, 2026, Pages 717-723]
Oxidative stress Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/Caspase-3, and TLR4/NF-κB axis activatione [Volume 29, Issue 6, 2026, Pages 942-951]
Oxidative stress CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease [Volume 29, Issue 6, 2026, Pages 915-926]
Oxidative stress Protective efficacy of thymol in testicular ischemia/reperfusion injury in rats: A biochemical and histopathological evaluation [Volume 29, Issue 7, 2026, Pages 1115-1121]
Oxidative stress Ponicidin alleviates atherosclerosis by inhibiting inflammation and oxidative stress through the SIRT1 and PI3K/Akt pathway [Volume 29, Issue 8, 2026, Pages 1195-1201]
Oxidative stress -reperfusion Cannabidiol attenuates lung ischemia-reperfusion injury by modulating RIPK1/RIPK3-mediated necroptosis and HIF-1α/VEGF signaling [Volume 29, Issue 5, 2026, Pages 766-773]
Oxidized pullulan Therapeutic potential of a pullulan polysaccharide-based hydrogel with antibacterial peptide for skin wound healing [Volume 29, Issue 3, 2026, Pages 412-422]

P

Paclitaxel Synergistic induction of apoptosis in cancer cells by combined silver nanoparticles and paclitaxel [Volume 29, Issue 4, 2026, Pages 634-640]
Paclitaxel Eugenol attenuates paclitaxel-induced cardiotoxicity by modulating autophagy-related markers in rats [Volume 29, Issue 5, 2026, Pages 794-803]
Pain Rosemary (Rosmarinus officinalis L.) and nervous system disorders: New findings on its neuroprotective properties [Volume 29, Issue 2, 2026, Pages 155-180]
Pain Inhibition of the PKC-TRPV1-SP axis by propolis ameliorates chronic inflammatory pain in mice [Volume 29, Issue 5, 2026, Pages 744-751]
Papillomavirus Vitamin C In vivo assessment of imoxide and diluted vitamin C’s inhibitory effects on cervical cancer in mice [Volume 29, Issue 6, 2026, Pages 971-978]
Paracrine factors Conditioned medium from mesenchymal stem cells: Towards skin tissue engineering and wound healing [Volume 29, Issue 2, 2026, Pages 181-190]
Parkinson’s Raspberry protective role in inflammatory diseases: An overview [Volume 29, Issue 1, 2026, Pages 22-33]
Parkinson’s disease Rosemary (Rosmarinus officinalis L.) and nervous system disorders: New findings on its neuroprotective properties [Volume 29, Issue 2, 2026, Pages 155-180]
Parkinson’s disease CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease [Volume 29, Issue 6, 2026, Pages 915-926]
Parthenolide Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity [Volume 29, Issue 1, 2026, Pages 90-100]
PD0325901 Impact of TGF-β and ERK1/2 inhibition on preimplantation embryo development and quality [Volume 29, Issue 4, 2026, Pages 578-589]
PD-1/PD-L1 Non-coding RNAs related to PD1/PD-L1 signaling with potential diagnostic, prognostic, and therapeutic value in the tumorigenesis of brain cancers [Volume 29, Issue 8, 2026, Pages 1174-1183]
PDMS Fabrication of a five-layer wound dressing containing chitosan-LL37 peptide for the treatment of EB wounds and deep exudate patients [Volume 29, Issue 8, 2026, Pages 1229-1240]
Peptides/chemistry Repurposing an antimicrobial arginine-rich decapeptide as a novel anticancer agent: Evidence from in vitro and in vivo breast cancer models [Volume 29, Issue 5, 2026, Pages 736-743]
PET Imaging Synthesis, radiolabeling, and biodistribution evaluation of novel hyperbranched polyglycerols-based radiotracers for targeting PSMA in prostate cancer [Volume 29, Issue 7, 2026, Pages 1089-1099]
Pharmacokinetics Kurarinone: From chemistry to pharmacological values–A review [Volume 29, Issue 5, 2026, Pages 675-687]
Pharmacology Kurarinone: From chemistry to pharmacological values–A review [Volume 29, Issue 5, 2026, Pages 675-687]
Phenolic content Evaluation of cytotoxic, anti-oxidant, and apoptotic effects of Dysphania botrys extract on B16F10 and MCF-7 cell lines [Volume 29, Issue 1, 2026, Pages 74-80]
Phenols Syringic acid attenuates LPS-induced acute lung injury via modulation of the HMGB1/TLR4/NF-κB and Keap1/Nrf2/HO-1 pathways: Mechanistic insights from in vivo and in silico studies [Volume 29, Issue 2, 2026, Pages 302-312]
Phytochemicals Compromised blood-brain barrier in traumatic brain injury model of Danio rerio: A unique window to demonstrate restoration of behavioral, cellular, and neurochemical deficits by limonin [Volume 29, Issue 3, 2026, Pages 468-481]
Phytochemistry Kurarinone: From chemistry to pharmacological values–A review [Volume 29, Issue 5, 2026, Pages 675-687]
Phytoestrogens Comparative effects of estradiol and daidzein on the expression of endometrial cancer-related genes and histopathological parameters in the uterus of ovariectomized rats [Volume 29, Issue 1, 2026, Pages 145-154]
Phytotherapy Rosa damascena in exercise-induced neuroinflammation and recovery: A narrative review bridging traditional medicine and translational sports science [Volume 29, Issue 5, 2026, Pages 641-656]
PI3K/Akt/mTOR Neuroprotective effects of ROCK inhibition on hippocampal energy metabolism in a rat model of metabolic syndrome [Volume 29, Issue 8, 2026, Pages 1286-1295]
PI3K/AKT/mTOR signaling- pathway Protective effects and mechanism of chrysophanol against age-related osteoporosis in rats [Volume 29, Issue 5, 2026, Pages 724-729]
Pitolisant Pitolisant disrupts memory consolidation and hippocampal synaptic plasticity: Impaired excitability and long-term potentiation in the CA1 area [Volume 29, Issue 3, 2026, Pages 378-386]
Platelet-rich plasma Transforming PRP into a Shelf-Stable therapy: Lyophilization preserves angiogenic and regenerative properties [Volume 29, Issue 5, 2026, Pages 782-793]
Pluronic Improved bioavailability of raloxifene hydrochloride through nasal administration of poly (methyl vinyl ether-co-maleic acid) nanoparticles in ovariectomized rats [Volume 29, Issue 2, 2026, Pages 202-211]
Polymeric micelle Development of a hybrid micelle–hydrogel system for topical delivery of doxorubicin to skin cancer cells [Volume 29, Issue 8, 2026, Pages 1184-1194]
Poly (Methyl vinyl ether-co-maleic acid) nanoparticles Improved bioavailability of raloxifene hydrochloride through nasal administration of poly (methyl vinyl ether-co-maleic acid) nanoparticles in ovariectomized rats [Volume 29, Issue 2, 2026, Pages 202-211]
Ponicidin Ponicidin alleviates atherosclerosis by inhibiting inflammation and oxidative stress through the SIRT1 and PI3K/Akt pathway [Volume 29, Issue 8, 2026, Pages 1195-1201]
Post-traumatic stress - disorder (PTSD) The effect of tert-butylhydroquinone on anxiolytic- and antidepressant-like behaviors induced by post-traumatic stress disorder: A behavioral and molecular study [Volume 29, Issue 1, 2026, Pages 113-120]
Precision Medicine Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer [Volume 29, Issue 5, 2026, Pages 688-716]
Pre-implantation embryo Impact of TGF-β and ERK1/2 inhibition on preimplantation embryo development and quality [Volume 29, Issue 4, 2026, Pages 578-589]
Probiotic Combining sorafenib and Lactobacillus rhamnosus GG reduces liver fibrosis and hepatic encephalopathy following bile duct ligation in rats [Volume 29, Issue 5, 2026, Pages 752-765]
Programmed cell death- ligand 1 Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer [Volume 29, Issue 5, 2026, Pages 688-716]
Propolis Inhibition of the PKC-TRPV1-SP axis by propolis ameliorates chronic inflammatory pain in mice [Volume 29, Issue 5, 2026, Pages 744-751]
Prostate cancer Synthesis, radiolabeling, and biodistribution evaluation of novel hyperbranched polyglycerols-based radiotracers for targeting PSMA in prostate cancer [Volume 29, Issue 7, 2026, Pages 1089-1099]
Prostate hyperplasia Cinnamophilin ameliorates testosterone-induced prostatic hyperplasia and fibrosis by regulating 5α-reductase and TGF-β/Smad signaling pathway [Volume 29, Issue 1, 2026, Pages 121-127]
Prostate-specific membrane antigen (PSMA) Comparative analysis of second and third-generation nanobody-based CAR-NK cells targeting PSMA in prostate cancer immunotherapy: In silico and in vitro studies [Volume 29, Issue 7, 2026, Pages 1122-1130]
Prostatic Neoplasms Comparative analysis of second and third-generation nanobody-based CAR-NK cells targeting PSMA in prostate cancer immunotherapy: In silico and in vitro studies [Volume 29, Issue 7, 2026, Pages 1122-1130]
Protective agent Hepatoprotective effect of hUC-MSC secretome in LPS-induced HepG2 cells [Volume 29, Issue 6, 2026, Pages 901-908]
Protein Serine-Threonine Kinase 1 (RIPK1) Cordycepin ameliorates ischemia/reperfusion-induced acute kidney injury via inhibiting apoptosis and necroptosis [Volume 29, Issue 8, 2026, Pages 1218-1228]
Protocatechuic acid Protocatechuic acid mitigates diazinon-induced lung injury in rats through modulation of oxidative stress, inflammatory, Keap-1/Nrf-2/HO-1 and ER stress-mediated apoptotic pathways [Volume 29, Issue 2, 2026, Pages 261-270]
Protoporphyrin IX An in vivo study on sonodynamic effects mediated by nanomicelles containing PpIX as a sonosensitizing agent [Volume 29, Issue 2, 2026, Pages 225-230]
PSMA Synthesis, radiolabeling, and biodistribution evaluation of novel hyperbranched polyglycerols-based radiotracers for targeting PSMA in prostate cancer [Volume 29, Issue 7, 2026, Pages 1089-1099]
Pulmonary delivery Cannabidiol: Pharmaceutical formulations and biomedical applications [Volume 29, Issue 4, 2026, Pages 522-530]
Pulmonary disease T-Lymphocytes Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD [Volume 29, Issue 2, 2026, Pages 231-239]
Pyroptosis Mitigation of sepsis-associated acute kidney injury by thymoquinone via targeting pyroptosis and attenuation of inflammation in C57BL/6 mice [Volume 29, Issue 5, 2026, Pages 717-723]
Python analysis LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of immune checkpoint proteins in HCC with python analysis [Volume 29, Issue 6, 2026, Pages 935-941]

R

Radiotherapy Radiotherapy-associated changes in the miR-124/SP1 axis in a rat glioma model [Volume 29, Issue 8, 2026, Pages 1211-1217]
Raloxifene hydrochloride Improved bioavailability of raloxifene hydrochloride through nasal administration of poly (methyl vinyl ether-co-maleic acid) nanoparticles in ovariectomized rats [Volume 29, Issue 2, 2026, Pages 202-211]
Raspberry Raspberry protective role in inflammatory diseases: An overview [Volume 29, Issue 1, 2026, Pages 22-33]
Rat Mechanistic insights into the protective effects of vitamin E against olanzapine-induced testicular toxicity: The role of microRNAs in oxidative stress and apoptosis [Volume 29, Issue 6, 2026, Pages 883-892]
Rats Comparative effects of estradiol and daidzein on the expression of endometrial cancer-related genes and histopathological parameters in the uterus of ovariectomized rats [Volume 29, Issue 1, 2026, Pages 145-154]
Rats Eugenol attenuates paclitaxel-induced cardiotoxicity by modulating autophagy-related markers in rats [Volume 29, Issue 5, 2026, Pages 794-803]
Reactive Oxygen Species Combined effects of EGCG and retinol on viability and apoptosis-related gene expression in Caco-2 and HCT-116 colon cancer cells [Volume 29, Issue 6, 2026, Pages 909-914]
Receptor Delta opioid peptide (D-Ala2, D-Leu5)-enkephalin (DADLE) mitigates myocardial ischemia-reperfusion injury by inhibiting the TRAF6/NF-κB/NLRP3 pathway [Volume 29, Issue 2, 2026, Pages 218-224]
Receptor-Interacting Cordycepin ameliorates ischemia/reperfusion-induced acute kidney injury via inhibiting apoptosis and necroptosis [Volume 29, Issue 8, 2026, Pages 1218-1228]
Regenerative medicine Transforming PRP into a Shelf-Stable therapy: Lyophilization preserves angiogenic and regenerative properties [Volume 29, Issue 5, 2026, Pages 782-793]
Regenerative medicine An in-depth examination of bone avascular necrosis and early-stage treatment modalities utilizing regenerative medicine [Volume 29, Issue 8, 2026, Pages 1131-1153]
Remote ischemic-preconditioning Remote ischemic preconditioning protects heart via modulation of purinergic signaling and AMPK-mediated autophagy in rat model of ischemia reperfusion injury [Volume 29, Issue 4, 2026, Pages 558-569]
Reproductive health The role of oxidative stress in sleep deprivation-induced reproductive dysfunction: A rationale for anti-oxidant intervention [Volume 29, Issue 2, 2026, Pages 191-201]
Resveratrol The protective effect of resveratrol on lupus nephritis mice by up-regulating Sirt1 [Volume 29, Issue 1, 2026, Pages 138-144]
Resveratrol Resveratrol mitigates diazinon-induced neurotoxicity during fetal brain development [Volume 29, Issue 8, 2026, Pages 1249-1258]
Retinol Combined effects of EGCG and retinol on viability and apoptosis-related gene expression in Caco-2 and HCT-116 colon cancer cells [Volume 29, Issue 6, 2026, Pages 909-914]
Rheumatoid arthritis CD73 blockade alleviates collagen-induced arthritis by inhibiting synovial fibroblast activity [Volume 29, Issue 5, 2026, Pages 774-781]
Rho-associated kinase Norepinephrine promotes the proliferation, migration, and phenotypic transformation of renal artery vascular smooth muscle cells via ROCK1 [Volume 29, Issue 4, 2026, Pages 605-612]
Rho-kinase (ROCK) Neuroprotective effects of ROCK inhibition on hippocampal energy metabolism in a rat model of metabolic syndrome [Volume 29, Issue 8, 2026, Pages 1286-1295]
Ribonucleoprotein complex Allele-specific disruption of KRAS p.G12V in colorectal cancer cells using electroporated Cas9 RNPs [Volume 29, Issue 8, 2026, Pages 1278-1285]
RNA Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey [Volume 29, Issue 6, 2026, Pages 812-822]
RNA interference Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey [Volume 29, Issue 6, 2026, Pages 812-822]
Rno-miR-124-3p Radiotherapy-associated changes in the miR-124/SP1 axis in a rat glioma model [Volume 29, Issue 8, 2026, Pages 1211-1217]
Rosa damascena Rosa damascena in exercise-induced neuroinflammation and recovery: A narrative review bridging traditional medicine and translational sports science [Volume 29, Issue 5, 2026, Pages 641-656]
Rosemary oil Rosemary inhalation improves the behavior and cognition of vascular cognitive impairment rats by regulating SIRT1/mTOR pathway-mediated cell apoptosis and autophagy [Volume 29, Issue 8, 2026, Pages 1269-1277]
Rosmarinic acid Rosemary (Rosmarinus officinalis L.) and nervous system disorders: New findings on its neuroprotective properties [Volume 29, Issue 2, 2026, Pages 155-180]
Rosmarinic acid Investigation of neuroprotective and antiapoptotic effects of rosmarinic acid in an in vitro Alzheimer’s disease model [Volume 29, Issue 8, 2026, Pages 1241-1248]
Rotundic acid In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3 [Volume 29, Issue 3, 2026, Pages 401-411]

S

Salvin Rosemary (Rosmarinus officinalis L.) and nervous system disorders: New findings on its neuroprotective properties [Volume 29, Issue 2, 2026, Pages 155-180]
Satellite cells Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]
SB431542 Impact of TGF-β and ERK1/2 inhibition on preimplantation embryo development and quality [Volume 29, Issue 4, 2026, Pages 578-589]
ScFv antibody Bioinformatic analysis and characterization of the Anti-CD20 scFv-Conjugated Fe₃O₄ nanoparticles for targeted therapy of CD20⁺ leukemia cells [Volume 29, Issue 8, 2026, Pages 1259-1268]
Schiff base reaction Therapeutic potential of a pullulan polysaccharide-based hydrogel with antibacterial peptide for skin wound healing [Volume 29, Issue 3, 2026, Pages 412-422]
Secretome Hepatoprotective effect of hUC-MSC secretome in LPS-induced HepG2 cells [Volume 29, Issue 6, 2026, Pages 901-908]
Sentinel lymph nodes Phenotypic alterations in the immune system and tolerance induction in tumor-draining lymph nodes [Volume 29, Issue 4, 2026, Pages 488-497]
Serotonin Promising therapeutic efficacy of kolaviron against prenatal valproate-induced autism spectrum disorder [Volume 29, Issue 8, 2026, Pages 1202-1210]
Silver Synergistic induction of apoptosis in cancer cells by combined silver nanoparticles and paclitaxel [Volume 29, Issue 4, 2026, Pages 634-640]
Silver nanoparticles 18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats [Volume 29, Issue 1, 2026, Pages 81-89]
Single-domain antibodies (Nanobodies) Comparative analysis of second and third-generation nanobody-based CAR-NK cells targeting PSMA in prostate cancer immunotherapy: In silico and in vitro studies [Volume 29, Issue 7, 2026, Pages 1122-1130]
SIRT1 The protective effect of resveratrol on lupus nephritis mice by up-regulating Sirt1 [Volume 29, Issue 1, 2026, Pages 138-144]
SIRT1 Ponicidin alleviates atherosclerosis by inhibiting inflammation and oxidative stress through the SIRT1 and PI3K/Akt pathway [Volume 29, Issue 8, 2026, Pages 1195-1201]
SIRT1 Rosemary inhalation improves the behavior and cognition of vascular cognitive impairment rats by regulating SIRT1/mTOR pathway-mediated cell apoptosis and autophagy [Volume 29, Issue 8, 2026, Pages 1269-1277]
Skin barrier function STAT3 ablation in keratinocytes ameliorates allergic contact dermatitis in DNCB-induced mice model [Volume 29, Issue 6, 2026, Pages 961-970]
Skin regeneration Therapeutic potential of a pullulan polysaccharide-based hydrogel with antibacterial peptide for skin wound healing [Volume 29, Issue 3, 2026, Pages 412-422]
Skp2 LKB1 dictates sensitivity to immunotherapy through Skp2-mediated ubiquitination of immune checkpoint proteins in HCC with python analysis [Volume 29, Issue 6, 2026, Pages 935-941]
Sleep deprivation The role of oxidative stress in sleep deprivation-induced reproductive dysfunction: A rationale for anti-oxidant intervention [Volume 29, Issue 2, 2026, Pages 191-201]
Smad Cinnamophilin ameliorates testosterone-induced prostatic hyperplasia and fibrosis by regulating 5α-reductase and TGF-β/Smad signaling pathway [Volume 29, Issue 1, 2026, Pages 121-127]
Small interfering Emerging trends in nanomedicine: The role of RNAi-based therapies and onpattro’s clinical journey [Volume 29, Issue 6, 2026, Pages 812-822]
Small-molecule drugs Targeting amyloid-β in Alzheimer’s disease: A critical analysis of clinical trials and their implications for drug development [Volume 29, Issue 4, 2026, Pages 531-543]
Sonoporation Ultrasound medicine in the era of precision theranostics: Mechanisms, molecular strategies, and clinical translation [Volume 29, Issue 4, 2026, Pages 498-521]
Sonoporation Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]
Sophora flavescens Kurarinone: From chemistry to pharmacological values–A review [Volume 29, Issue 5, 2026, Pages 675-687]
Sorafenib Combining sorafenib and Lactobacillus rhamnosus GG reduces liver fibrosis and hepatic encephalopathy following bile duct ligation in rats [Volume 29, Issue 5, 2026, Pages 752-765]
Sorafenib Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [Volume 29, Issue 6, 2026, Pages 870-882]
Sp1 transcription factor Radiotherapy-associated changes in the miR-124/SP1 axis in a rat glioma model [Volume 29, Issue 8, 2026, Pages 1211-1217]
Squamous Cell Hyaluronic acid-coated niosomal sorafenib targets CD44 and suppresses NF‑κB signalling in oral squamous cell carcinoma [Volume 29, Issue 6, 2026, Pages 870-882]
STAT3 STAT3 ablation in keratinocytes ameliorates allergic contact dermatitis in DNCB-induced mice model [Volume 29, Issue 6, 2026, Pages 961-970]
Stem cell therapy An in-depth examination of bone avascular necrosis and early-stage treatment modalities utilizing regenerative medicine [Volume 29, Issue 8, 2026, Pages 1131-1153]
Streptozocin The effect(s) of berberine from Berberis vulgaris L. (Berberidaceae) on treating type 1 diabetes mellitus in streptozotocin-induced diabetic rats [Volume 29, Issue 4, 2026, Pages 613-622]
Streptozotocin Hispidulin: A potential antihyperglycemic and anti-oxidant agent-mechanistic insights into its modulatory effects on PI3K, AKT, mTOR, IRS1, GSK-3β, and GLUT-4 pathways through in vitro and in vivo studies [Volume 29, Issue 2, 2026, Pages 240-248]
Swiss albino mice In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3 [Volume 29, Issue 3, 2026, Pages 401-411]
Synaptic plasticity Pitolisant disrupts memory consolidation and hippocampal synaptic plasticity: Impaired excitability and long-term potentiation in the CA1 area [Volume 29, Issue 3, 2026, Pages 378-386]
Synovial fibroblasts CD73 blockade alleviates collagen-induced arthritis by inhibiting synovial fibroblast activity [Volume 29, Issue 5, 2026, Pages 774-781]
Synovial inflammation CD73 blockade alleviates collagen-induced arthritis by inhibiting synovial fibroblast activity [Volume 29, Issue 5, 2026, Pages 774-781]

T

Tert-butylhydroquinone (tBHQ) The effect of tert-butylhydroquinone on anxiolytic- and antidepressant-like behaviors induced by post-traumatic stress disorder: A behavioral and molecular study [Volume 29, Issue 1, 2026, Pages 113-120]
Testicular torsion Protective efficacy of thymol in testicular ischemia/reperfusion injury in rats: A biochemical and histopathological evaluation [Volume 29, Issue 7, 2026, Pages 1115-1121]
TGF-β Cinnamophilin ameliorates testosterone-induced prostatic hyperplasia and fibrosis by regulating 5α-reductase and TGF-β/Smad signaling pathway [Volume 29, Issue 1, 2026, Pages 121-127]
Theranostics Ultrasound medicine in the era of precision theranostics: Mechanisms, molecular strategies, and clinical translation [Volume 29, Issue 4, 2026, Pages 498-521]
Therapeutic ultrasound An in vivo study on sonodynamic effects mediated by nanomicelles containing PpIX as a sonosensitizing agent [Volume 29, Issue 2, 2026, Pages 225-230]
Thermoreversible gels Improved bioavailability of raloxifene hydrochloride through nasal administration of poly (methyl vinyl ether-co-maleic acid) nanoparticles in ovariectomized rats [Volume 29, Issue 2, 2026, Pages 202-211]
Thymol Protective efficacy of thymol in testicular ischemia/reperfusion injury in rats: A biochemical and histopathological evaluation [Volume 29, Issue 7, 2026, Pages 1115-1121]
Thymoquinone Mitigation of sepsis-associated acute kidney injury by thymoquinone via targeting pyroptosis and attenuation of inflammation in C57BL/6 mice [Volume 29, Issue 5, 2026, Pages 717-723]
Tissue engineering An in-depth examination of bone avascular necrosis and early-stage treatment modalities utilizing regenerative medicine [Volume 29, Issue 8, 2026, Pages 1131-1153]
Titanium prosthetics Beyond bioactivity: Chitosan macromolecular coatings on titanium surfaces drive osseointegration and immune suppression through targeted epigenetic regulation [Volume 29, Issue 7, 2026, Pages 1066-1078]
TLR4/NF-κB Trigonelline protects against alcohol-induced brain damage by inhibition of oxidative stress, TLR4/NF-κB/proinflammatory cytokines pathway, and apoptosis [Volume 29, Issue 7, 2026, Pages 1079-1088]
TNF receptor-associated factor 6 Delta opioid peptide (D-Ala2, D-Leu5)-enkephalin (DADLE) mitigates myocardial ischemia-reperfusion injury by inhibiting the TRAF6/NF-κB/NLRP3 pathway [Volume 29, Issue 2, 2026, Pages 218-224]
Toll-like receptor 2 Investigating the protective effect of zinc supplementation on streptozotocin-induced pancreatic beta-cell damage via the HMGB1/TLR2/MAPK pathway [Volume 29, Issue 7, 2026, Pages 1020-1026]
Traditional Medicine Rosa damascena in exercise-induced neuroinflammation and recovery: A narrative review bridging traditional medicine and translational sports science [Volume 29, Issue 5, 2026, Pages 641-656]
Transcription factors Can monomethyl fumarate and nifedipine reduce ischemia reperfusion injury in rat ovary, and what is the share of oxidative stress-sensitive transcription factors HIF-1a, Nfkb, and Nrf2? [Volume 29, Issue 3, 2026, Pages 446-457]
Transcription factors Resveratrol mitigates diazinon-induced neurotoxicity during fetal brain development [Volume 29, Issue 8, 2026, Pages 1249-1258]
Transforming growth An in vivo evaluation of the antifibrotic potential of inulin against bile duct ligation-induced liver fibrosis [Volume 29, Issue 2, 2026, Pages 271-279]
Transforming growth factor- beta Impact of TGF-β and ERK1/2 inhibition on preimplantation embryo development and quality [Volume 29, Issue 4, 2026, Pages 578-589]
Transmucosal delivery Cannabidiol: Pharmaceutical formulations and biomedical applications [Volume 29, Issue 4, 2026, Pages 522-530]
Trans sodium crocetinate Trans sodium crocetinate protects against hepatotoxicity induced by bisphenol A in rats [Volume 29, Issue 4, 2026, Pages 570-577]
Traumatic brain injury Compromised blood-brain barrier in traumatic brain injury model of Danio rerio: A unique window to demonstrate restoration of behavioral, cellular, and neurochemical deficits by limonin [Volume 29, Issue 3, 2026, Pages 468-481]
Traumatic brain injury HIPK2 protects neurons from oxidative stress and modulates central nervous system responses following traumatic brain injury [Volume 29, Issue 5, 2026, Pages 804-811]
Trigonelline Trigonelline protects against alcohol-induced brain damage by inhibition of oxidative stress, TLR4/NF-κB/proinflammatory cytokines pathway, and apoptosis [Volume 29, Issue 7, 2026, Pages 1079-1088]
Triple negative breast- neoplasms AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery [Volume 29, Issue 6, 2026, Pages 823-843]
TRPA1 Dexmedetomidine protects against ischemia and reperfusion-induced kidney injury in rats by inhibiting the expression of TRPM2 and TRPA1 channels [Volume 29, Issue 4, 2026, Pages 590-597]
TRPM2 Dexmedetomidine protects against ischemia and reperfusion-induced kidney injury in rats by inhibiting the expression of TRPM2 and TRPA1 channels [Volume 29, Issue 4, 2026, Pages 590-597]
Tuberculosis A review on recent advances in lipid-based drug delivery systems for tuberculosis [Volume 29, Issue 3, 2026, Pages 322-333]
Tumor cell line Radiotherapy-associated changes in the miR-124/SP1 axis in a rat glioma model [Volume 29, Issue 8, 2026, Pages 1211-1217]
Tumor Microenvironment Hypoxic tumor microenvironment and immune cell dynamics: From metabolic reprogramming to therapeutic innovation [Volume 29, Issue 3, 2026, Pages 334-352]
Tumor Microenvironment Antibody therapies in glioblastoma: Overcoming micro-environmental barriers [Volume 29, Issue 3, 2026, Pages 353-377]
Tumor Microenvironment Phenotypic alterations in the immune system and tolerance induction in tumor-draining lymph nodes [Volume 29, Issue 4, 2026, Pages 488-497]

V

Valproic acid Promising therapeutic efficacy of kolaviron against prenatal valproate-induced autism spectrum disorder [Volume 29, Issue 8, 2026, Pages 1202-1210]
Vanillin Synergistic myelin regenerative, immunomodulatory and anti-inflammatory effects of vanillin and adipose derived stem cells in cuprizone animal model of multiple sclerosis [Volume 29, Issue 7, 2026, Pages 1027-1034]
Vascular cognitive - impairment Electroacupuncture improves hypoxic stress and energy metabolism to alleviate vascular cognitive impairment through activation of the HIF-1α/p53/NGB signaling pathway in rats [Volume 29, Issue 1, 2026, Pages 34-42]
Vascular endothelial Growth factor A Cannabidiol attenuates lung ischemia-reperfusion injury by modulating RIPK1/RIPK3-mediated necroptosis and HIF-1α/VEGF signaling [Volume 29, Issue 5, 2026, Pages 766-773]
Vascular smooth muscle- cells Norepinephrine promotes the proliferation, migration, and phenotypic transformation of renal artery vascular smooth muscle cells via ROCK1 [Volume 29, Issue 4, 2026, Pages 605-612]
VDAC Involvement of SIRT3 downstream targets ANT1, VDAC, CYPD, and Drp1 in a rat model of hepatic encephalopathy: Therapeutic role of thymoquinone [Volume 29, Issue 6, 2026, Pages 952-960]
Ventrolateral periaqueductal- gray Cardiovascular effects of ventrolateral periaqueductal gray (vlPAG) AT1 receptors in normotensive and hemorrhagic rats [Volume 29, Issue 2, 2026, Pages 290-301]
Vitamin E Mechanistic insights into the protective effects of vitamin E against olanzapine-induced testicular toxicity: The role of microRNAs in oxidative stress and apoptosis [Volume 29, Issue 6, 2026, Pages 883-892]
Volumetric muscle loss Musculoskeletal ultrasound-guided cellular therapy: Current applications and future directions in skeletal muscle regeneration [Volume 29, Issue 8, 2026, Pages 1154-1173]

Iranian Journal of Basic Medical Sciences

Keyword Index

A

B

C

D

E

F

G

H

I

J

K

L

M

N

O

P

Q

R

S

T

U

V

W

Z