Iranian Journal of Basic Medical Sciences

Keywords = Oxidative stress

Hesperidin mitigates DEHP-induced nephrotoxicity through anti-oxidant, anti-apoptotic, and anti-inflammatory pathway modulation: Evidence from Nrf2/HO-1/Keap-1, Bax/Bcl-2/Caspase-3, and TLR4/NF-κB axis activatione

Articles in Press, Accepted Manuscript, Available Online from 02 May 2026

10.22038/ijbms.2026.89049.19222

Tuba Karaarslan; Betul Apaydin Yildirim; Fatih Yildirim; Omercan Alat

CRISPR/Cas9-mediated knockout of NEAT1 attenuates neurotoxicity in 6-hydroxydopamine model of Parkinson’s disease

Articles in Press, Accepted Manuscript, Available Online from 06 May 2026

10.22038/ijbms.2026.93063.20075

Ali Samareh; Mohammad Hadi Nematollahi; Hossein Pourghadamyari; Sanaz Rastegar; Hosseinali Ebrahimi; Morteza Hadizadeh; Hongsheng Wang; Lijun Tao; Hosseinali Sasan; Gholamreza Asadikaram

Rosa damascena in exercise-induced neuroinflammation and recovery: A narrative review bridging traditional medicine and translational sports science

Volume 29, Issue 5, May 2026, Pages 641-656

10.22038/ijbms.2026.89043.19219

Babak Hooshmand-Moghadam; Abbas Ali Gaeini

Mitigation of sepsis-associated acute kidney injury by thymoquinone via targeting pyroptosis and attenuation of inflammation in C57BL/6 mice

Volume 29, Issue 5, May 2026, Pages 717-723

10.22038/ijbms.2026.92268.19913

Niloofar Izadi; Mahdieh Taheri; Mehrdad Roghani

Eugenol attenuates paclitaxel-induced cardiotoxicity by modulating autophagy-related markers in rats

Volume 29, Issue 5, May 2026, Pages 794-803

10.22038/ijbms.2026.89478.19317

Halime Tozak Yıldız; Sadık Küçükgünay; Oya Korkmaz; Seda Koçak; Mustafa Numan Bucak

HIPK2 protects neurons from oxidative stress and modulates central nervous system responses following traumatic brain injury

Volume 29, Issue 5, May 2026, Pages 804-811

10.22038/ijbms.2026.90522.19511

Qiangbin Zhu; Fan Wang; Bojun Zhang; Zhigang Pan; Xiaodong Kang; Weipeng Hu

Trans sodium crocetinate protects against hepatotoxicity induced by bisphenol A in rats

Volume 29, Issue 4, April 2026, Pages 570-577

10.22038/ijbms.2026.87985.19073

Majid keshavarzi; Bibi Marjan Razavi; Hossein Hosseinzadeh

Comparison of long non-coding RNA NEAT1 expression, P53, and antioxidant factors between Alzheimer’s patients and healthy individuals

Volume 29, Issue 4, April 2026, Pages 598-604

10.22038/ijbms.2026.89576.19336

Sara Yarahmadi; Leila Alidoust; Alia Saberi; Behrooz Khakpour-Taleghani; Mohamad Rostampour; Adele Jafari

Mechanistic pathways and in silico modeling of gallic acid–mediated protection against doxorubicin-induced nephrotoxicity in rats

Volume 29, Issue 4, April 2026, Pages 623-633

10.22038/ijbms.2026.90473.19500

Samet Teki̇n; Burak Çinar; Yusuf Dağ; Aslıhan Atasever; Merve Bolat; İsmail Bolat; Burak Batuhan Laçi̇n; Emin Şengül; Serkan Yıldırım; Mohamad Warda

Effects of minocycline on acrylamide-induced neurotoxicity in Wistar rats

Volume 29, Issue 3, March 2026, Pages 393-400

10.22038/ijbms.2026.87102.18836

Neda Vatankhah; Mahboobeh Ghasemzadeh Rahbardar; Soghra Mehri; Hossein Hosseinzadeh

In silico and in vivo investigation of rotundic acid for its effect on cyclophosphamide-induced cardiotoxicity in Swiss albino mice; targeting TLR4/ NF-κB/ cleaved caspase-3

Volume 29, Issue 3, March 2026, Pages 401-411

10.22038/ijbms.2026.87759.18960

Mohammad Moonis; Mirza Sarwar Baig; Divya Vohora; Syed Ehtaishamul Haque

Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling

Volume 29, Issue 3, March 2026, Pages 423-437

10.22038/ijbms.2026.89093.19230

Amber Mahmood Minhas; Arif Ullah Khan; Neelum Gul Qazi; Humaira Nadeem; Fawad Ali

Can monomethyl fumarate and nifedipine reduce ischemia reperfusion injury in rat ovary, and what is the share of oxidative stress-sensitive transcription factors HIF-1a, Nfkb, and Nrf2?

Volume 29, Issue 3, March 2026, Pages 446-457

10.22038/ijbms.2026.89192.19254

Begum Kurt; Zeynep Deniz Sahin Inan; Sevgi Durna Dastan; Göknil Pelin Coskun; Ali Cetin

Fluoxetine attenuates UPR-activation, neuroinflammation, and oxidative stress in a nitroglycerin-induced rat model of migraine

Volume 29, Issue 3, March 2026, Pages 458-467

10.22038/ijbms.2026.90321.19468

Mahnaz Sadat Moshtaghian; Amir Hossein Yousefi Nejad; Mohammad Reza Namavar; Fatemeh Zal; Sayed Mohammad Shafiee; Zahra Khoshdel

The role of oxidative stress in sleep deprivation-induced reproductive dysfunction: A rationale for anti-oxidant intervention

Volume 29, Issue 2, February 2026, Pages 191-201

10.22038/ijbms.2025.90559.19517

Keke Chen; Kaixing Huang; Xiaoyu Liu; Fengyou Luo; Qiping Hu; Changlong Xu

Anti-inflammatory and anti-oxidant efficacy of origanum species and honey in a rat model of COPD

Volume 29, Issue 2, February 2026, Pages 231-239

10.22038/ijbms.2025.89695.19351

Fadime Ovalı; Hüsamettin Vatansev; Hakan Vatansev; Bayram Çolak; İsmail Harmankaya

Syringic acid attenuates LPS-induced acute lung injury via modulation of the HMGB1/TLR4/NF-κB and Keap1/Nrf2/HO-1 pathways: Mechanistic insights from in vivo and in silico studies

Volume 29, Issue 2, February 2026, Pages 302-312

10.22038/ijbms.2026.90093.19427

Burak Batuhan Lacin; Emin Şengul; Serkan Yildirim; Furkan Aykurt; Mohamad Warda; Burak Cinar; Ali Cinar

Neuroprotective effects of kojic acid and nano-kojic acid in experimental brain ischemia induced by bilateral common carotid artery occlusion

Volume 29, Issue 1, January 2026, Pages 43-54

10.22038/ijbms.2025.89790.19367

Mohammad Shokati Sayyad; Majid Saeedi; Fatemeh Shaki; Fereshteh Talebpour Amiri; Reza Negarandeh; Mohammad Seyedabadi

18β-Glycyrrhetinic acid-loaded silver nanoparticles mitigate neuroinflammation and endoplasmic reticulum stress in the brain tissue of diabetic rats

Volume 29, Issue 1, January 2026, Pages 81-89

10.22038/ijbms.2025.86986.18801

Seçil Nazife Parlak; Seda Yakut; Adem Kara; Özlem Demir; Saime Özbek Şebin

The protective effect of resveratrol on lupus nephritis mice by up-regulating Sirt1

Volume 29, Issue 1, January 2026, Pages 138-144

10.22038/ijbms.2025.90231.19451

Yu Zhao; Yun Cai; Jie Chen; Yang Xu-yan

Comparative effects of estradiol and daidzein on the expression of endometrial cancer-related genes and histopathological parameters in the uterus of ovariectomized rats

Volume 29, Issue 1, January 2026, Pages 145-154

10.22038/ijbms.2025.89681.19349

Vahid Setayesh; Asma Neisy; Maryam Niknam; Zahra Khoshdel; Farhad Koohpeyma; Sanaz Alaee; Fatemeh Zal

Protective role of astaxanthin against bisphenol A induced biochemical and histopathological alterations in rat kidneys

Volume 28, Issue 12, December 2025, Pages 1647-1655

10.22038/ijbms.2025.88356.19081

Burcu Gultekin; Seda Çetinkaya; İlknur Çınar Ayan; Hasan Basri Savaş; Serpil Kalkan

Ficus carica leaf extract ameliorates cardiac injury through Nrf2/Keap1 pathway activation and dual oxidase inhibition

Volume 28, Issue 12, December 2025, Pages 1679-1690

10.22038/ijbms.2025.88664.19148

Najeeb Ullah Khan; Shamshad Ul Hassan; Bilal Aslam; Saqib Umer

Temporal dynamics of ferroptosis markers and neuroprotective intervention in cerebral ischemia-reperfusion injury: Insights for therapeutic strategy development

Volume 28, Issue 12, December 2025, Pages 1699-1705

10.22038/ijbms.2025.82625.17865

Shuangyan Bao; Chaojie Liu; Qian Wang; Chenggui Zhang; Hairong Zhao

Linalool vs linalool-loaded chitosan nanoparticles in an Aβ-induced rat model of Alzheimer’s disease: A molecular, biochemical, histological, and behavioral study

Volume 28, Issue 11, November 2025, Pages 1495-1504

10.22038/ijbms.2025.88638.19143

Mohammad Pakdel; Masoumeh Asle Rousta; Mehdi Sadegh; Akram Eidi

Iranian Journal of Basic Medical Sciences

Journal Archive

Volume 29 (2026)

Volume 28 (2025)

Volume 27 (2024)

Volume 26 (2023)

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Volume 24 (2021)

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