Iranian Journal of Basic Medical Sciences

Keyword Index

A

Acetylcholinesterase Alzheimer’s disease Dietary supplements for prevention of Alzheimer’s disease: In vivo and in silico molecular docking studies [Volume 28, Issue 2, 2025, Pages 170-180]
Acetylsalicylic acid Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis [Volume 28, Issue 2, 2025, Pages 209-216]
Acrylamide Cardiotoxicity caused by acrylamide in rats can be alleviated as a result of suppression of oxidative stress, endoplasmic reticulum stress, inflammation, and apoptosis by morin treatment [Volume 28, Issue 3, 2025, Pages 376-384]
Acute kidney injury Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats [Volume 28, Issue 5, 2025, Pages 612-619]
Acute liver injury Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice [Volume 28, Issue 1, 2025, Pages 87-97]
Adipogenesis In vitro effects of phytochemicals on adipogenesis with a focus on molecular mechanisms: A systematic review [Volume 28, Issue 4, 2025, Pages 409-425]
Adjuvant Protective immune response induced by cationic liposomes bearing soluble antigens improves the survival of BALB/c mice against Toxoplasma gondii RH strain [Volume 28, Issue 3, 2025, Pages 347-354]
Advanced Glycation End Products Meloxicam mitigated methylglyoxal-induced glycative stress in rats [Volume 28, Issue 5, 2025, Pages 647-654]
Akt Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma [Volume 28, Issue 1, 2025, Pages 113-120]
Akt Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression [Volume 28, Issue 4, 2025, Pages 493-497]
Akt Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway [Volume 28, Issue 4, 2025, Pages 401-408]
Akt/mTOR/p70S6K-signaling pathway The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration [Volume 28, Issue 3, 2025, Pages 393-400]
Alginate Regeneration of the skin wound by two different crosslinkers: In vitro and in vivo studies [Volume 28, Issue 2, 2025, Pages 194-208]
Alginate hydrogel Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery [Volume 28, Issue 5, 2025, Pages 627-637]
Alpha-pinene Alpha-pinene ameliorates liver fibrosis by suppressing oxidative stress, inflammation, and the TGF-β/Smad3 signaling pathway [Volume 28, Issue 4, 2025, Pages 451-460]
Alpha-synuclein Trans-sodium crocetinate ameliorates Parkinson-like disease caused by bisphenol A through inhibition of apoptosis and reduction of α-synuclein in rats [Volume 28, Issue 2, 2025, Pages 254-263]
Alzheimer’s Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: An overview [Volume 28, Issue 5, 2025, Pages 553-564]
Amantadine Amantadine reduces sepsis-induced brain injury via NLRP3/caspase-1 inflammasome activation [Volume 28, Issue 5, 2025, Pages 620-626]
AMPK ATP Effect of the S100A9/AMPK pathway on PM2.5-mediated mouse lung injury [Volume 28, Issue 1, 2025, Pages 121-129]
AMPK/mTOR pathway COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway [Volume 28, Issue 3, 2025, Pages 340-346]
Amyloid-β Dietary supplements for prevention of Alzheimer’s disease: In vivo and in silico molecular docking studies [Volume 28, Issue 2, 2025, Pages 170-180]
Anemoside B4 Effect of anemoside B4 on ameliorating cerebral ischemic/reperfusion injury [Volume 28, Issue 1, 2025, Pages 49-55]
Angiotensin II Echinacoside alleviates Ang II-induced cardiac fibrosis by enhancing the SIRT1/IL-11 pathway [Volume 28, Issue 1, 2025, Pages 130-140]
Anti-aging Enhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model [Volume 28, Issue 2, 2025, Pages 151-157]
Anti-inflammatory Rutin attenuates complete Freund’s adjuvant-induced inflammatory pain in rats [Volume 28, Issue 3, 2025, Pages 332-339]
Anti-oxidant Rutin attenuates complete Freund’s adjuvant-induced inflammatory pain in rats [Volume 28, Issue 3, 2025, Pages 332-339]
Antioxidants Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis [Volume 28, Issue 2, 2025, Pages 209-216]
Apigenin Apigenin attenuates myocardial ischemia-reperfusion injury through miR-448/SIRT1 axis [Volume 28, Issue 5, 2025, Pages 602-611]
Apoptosis Effect of anemoside B4 on ameliorating cerebral ischemic/reperfusion injury [Volume 28, Issue 1, 2025, Pages 49-55]
Apoptosis Lysyl oxidase-like 2 promotes the survival, migration, and ferroptosis of endometrial cancer cells by activating the phosphoinositide 3-kinase/protein kinase B pathway [Volume 28, Issue 1, 2025, Pages 72-79]
Apoptosis Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice [Volume 28, Issue 1, 2025, Pages 87-97]
Apoptosis Rosmarinic acid attenuated inflammation and apoptosis in folic acid-induced renal injury: Role of FoxO3/ NFκB pathway [Volume 28, Issue 3, 2025, Pages 316-322]
Apoptosis Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway [Volume 28, Issue 2, 2025, Pages 187-193]
Apoptosis The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration [Volume 28, Issue 3, 2025, Pages 393-400]
Apoptosis Cardiotoxicity caused by acrylamide in rats can be alleviated as a result of suppression of oxidative stress, endoplasmic reticulum stress, inflammation, and apoptosis by morin treatment [Volume 28, Issue 3, 2025, Pages 376-384]
Apoptosis COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway [Volume 28, Issue 3, 2025, Pages 340-346]
Apoptosis Trans-sodium crocetinate ameliorates Parkinson-like disease caused by bisphenol A through inhibition of apoptosis and reduction of α-synuclein in rats [Volume 28, Issue 2, 2025, Pages 254-263]
Apoptosis Pre- and post-traumatic boric acid therapy prevents oxidative stress-mediated neuronal apoptosis in spinal cord injury [Volume 28, Issue 4, 2025, Pages 444-450]
Apoptosis Apigenin attenuates myocardial ischemia-reperfusion injury through miR-448/SIRT1 axis [Volume 28, Issue 5, 2025, Pages 602-611]
Apoptosis Amantadine reduces sepsis-induced brain injury via NLRP3/caspase-1 inflammasome activation [Volume 28, Issue 5, 2025, Pages 620-626]
Apoptosis Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways [Volume 28, Issue 4, 2025, Pages 507-515]
Apoptosis Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats [Volume 28, Issue 5, 2025, Pages 612-619]
Apoptosis Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway [Volume 28, Issue 4, 2025, Pages 401-408]
Apoptosis Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery [Volume 28, Issue 5, 2025, Pages 627-637]
Apoptosis Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats [Volume 28, Issue 4, 2025, Pages 461-468]
Arrhythmia Effects of combo therapy with coenzyme Q10 and mitochondrial transplantation on myocardial ischemia/reperfusion-induced arrhythmias in aged rats [Volume 28, Issue 1, 2025, Pages 38-48]
Atherosclerosis Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: An overview [Volume 28, Issue 5, 2025, Pages 553-564]
Autophagy Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma [Volume 28, Issue 1, 2025, Pages 113-120]
Autophagy Trans-sodium crocetinate ameliorates Parkinson-like disease caused by bisphenol A through inhibition of apoptosis and reduction of α-synuclein in rats [Volume 28, Issue 2, 2025, Pages 254-263]
Autophagy Apigenin attenuates myocardial ischemia-reperfusion injury through miR-448/SIRT1 axis [Volume 28, Issue 5, 2025, Pages 602-611]
Autophagy Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway [Volume 28, Issue 4, 2025, Pages 401-408]

B

Bacteria Role of bacteria in cancers and their therapeutic potential: Review of current knowledge [Volume 28, Issue 3, 2025, Pages 273-282]
Basal forebrain Protective effect of Lavandula angustifolia essential oil inhalation on neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation [Volume 28, Issue 2, 2025, Pages 264-272]
BDNF Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats [Volume 28, Issue 3, 2025, Pages 283-291]
BDNF Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression [Volume 28, Issue 4, 2025, Pages 493-497]
Biomarker Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer [Volume 28, Issue 5, 2025, Pages 592-601]
Bisphenol A Trans-sodium crocetinate ameliorates Parkinson-like disease caused by bisphenol A through inhibition of apoptosis and reduction of α-synuclein in rats [Volume 28, Issue 2, 2025, Pages 254-263]
BLA Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats [Volume 28, Issue 3, 2025, Pages 283-291]
Bladder cancer COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway [Volume 28, Issue 3, 2025, Pages 340-346]
Boric acid Pre- and post-traumatic boric acid therapy prevents oxidative stress-mediated neuronal apoptosis in spinal cord injury [Volume 28, Issue 4, 2025, Pages 444-450]
Breast Cancer Infiltration of innate and adoptive lymphoid cells in 4T1 and MC4-L2 breast cancer models [Volume 28, Issue 1, 2025, Pages 63-71]
Brown fat tissue Endurance training promotes the browning of WAT by enhancing the NPFF pathway in the hypothalamus in rats with type 2 diabetes [Volume 28, Issue 5, 2025, Pages 575-583]

C

CaCl2 Regeneration of the skin wound by two different crosslinkers: In vitro and in vivo studies [Volume 28, Issue 2, 2025, Pages 194-208]
Cancer Advancing cancer treatment with nanozyme frameworks: Integrating photothermal, photodynamic, sonodynamic, and chemodynamic therapies [Volume 28, Issue 5, 2025, Pages 533-552]
Cancer Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: An overview [Volume 28, Issue 5, 2025, Pages 553-564]
Cancer therapy Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword [Volume 28, Issue 1, 2025, Pages 3-15]
Carbon tetrachloride Alpha-pinene ameliorates liver fibrosis by suppressing oxidative stress, inflammation, and the TGF-β/Smad3 signaling pathway [Volume 28, Issue 4, 2025, Pages 451-460]
Carboxymethyl cellulose Regeneration of the skin wound by two different crosslinkers: In vitro and in vivo studies [Volume 28, Issue 2, 2025, Pages 194-208]
Carboxymethyllysine Meloxicam mitigated methylglyoxal-induced glycative stress in rats [Volume 28, Issue 5, 2025, Pages 647-654]
Cardiac fibrosis Echinacoside Echinacoside alleviates Ang II-induced cardiac fibrosis by enhancing the SIRT1/IL-11 pathway [Volume 28, Issue 1, 2025, Pages 130-140]
Cardiac hypertrophy SIRT5 prevents mitochondrial dysfunction and cardiac hypertrophy induced by RIP140 [Volume 28, Issue 4, 2025, Pages 477-485]
Cardiac hypertrophy Pim3 up-regulation by YY1 contributes to diabetes-induced cardiac hypertrophy and heart failure [Volume 28, Issue 2, 2025, Pages 245-253]
Cardiotoxicity Cardiotoxicity caused by acrylamide in rats can be alleviated as a result of suppression of oxidative stress, endoplasmic reticulum stress, inflammation, and apoptosis by morin treatment [Volume 28, Issue 3, 2025, Pages 376-384]
Cardiovascular diseases Vanillic acid as a promising intervention for metabolic syndrome: Preclinical studies [Volume 28, Issue 2, 2025, Pages 141-150]
Cardiovascular diseases Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: An overview [Volume 28, Issue 5, 2025, Pages 553-564]
Cardiovascular system Glutamate receptors within the lateral periaqueductal gray (lPAG): Effects on blood pressure and heart rate in basic and hypotensive hemorrhagic rats [Volume 28, Issue 4, 2025, Pages 486-492]
Caspase 3 Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats [Volume 28, Issue 5, 2025, Pages 565-574]
Caspase-3 Sinapic acid attenuated nephrotoxicity against Cyclophosphamide in mice model: A histochemical, immunohistochemical and histopathological evaluation [Volume 28, Issue 5, 2025, Pages 655-661]
Castration Role of ENaC in gender-associated differences in blood pressure [Volume 28, Issue 4, 2025, Pages 527-532]
Cationic Liposome Protective immune response induced by cationic liposomes bearing soluble antigens improves the survival of BALB/c mice against Toxoplasma gondii RH strain [Volume 28, Issue 3, 2025, Pages 347-354]
CD4+ T-lymphocytes Infiltration of innate and adoptive lymphoid cells in 4T1 and MC4-L2 breast cancer models [Volume 28, Issue 1, 2025, Pages 63-71]
CD8+ T-lymphocytes Infiltration of innate and adoptive lymphoid cells in 4T1 and MC4-L2 breast cancer models [Volume 28, Issue 1, 2025, Pages 63-71]
Cell Proliferation Lysyl oxidase-like 2 promotes the survival, migration, and ferroptosis of endometrial cancer cells by activating the phosphoinositide 3-kinase/protein kinase B pathway [Volume 28, Issue 1, 2025, Pages 72-79]
Cell Proliferation Simultaneous effect of naringenin and beta-catenin signaling inhibitor C-82 on modulating gene expression and functional pattern of mesenchymal stem cells from endometriosis patients [Volume 28, Issue 5, 2025, Pages 671-679]
Cerebral ischemia/reperfusion Effect of anemoside B4 on ameliorating cerebral ischemic/reperfusion injury [Volume 28, Issue 1, 2025, Pages 49-55]
Cerebral ischemia/reperfusion injury Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury [Volume 28, Issue 1, 2025, Pages 105-112]
Chemodynamic Advancing cancer treatment with nanozyme frameworks: Integrating photothermal, photodynamic, sonodynamic, and chemodynamic therapies [Volume 28, Issue 5, 2025, Pages 533-552]
Chemoresistance Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword [Volume 28, Issue 1, 2025, Pages 3-15]
Chromosomes Effects of pentoxifylline on mouse oocytes maturation and qualityin vitro [Volume 28, Issue 3, 2025, Pages 310-315]
Chrysin Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin [Volume 28, Issue 4, 2025, Pages 516-526]
CircRNAs Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword [Volume 28, Issue 1, 2025, Pages 3-15]
Coenzyme Q10 Effects of combo therapy with coenzyme Q10 and mitochondrial transplantation on myocardial ischemia/reperfusion-induced arrhythmias in aged rats [Volume 28, Issue 1, 2025, Pages 38-48]
Cognition Comparing the effect of plasma therapy with estradiol valerate in motor and cognitive behavioral disorders in ovariectomized old rats: Behavioral, biochemical, and protein expression [Volume 28, Issue 3, 2025, Pages 366-375]
COL3A1 Enhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model [Volume 28, Issue 2, 2025, Pages 151-157]
Cold Temperature Synergistic effect of cold atmospheric plasma and methylene blue loaded nano micelles on treating human glioblastoma cells: An in vitro and molecular dynamics study [Volume 28, Issue 3, 2025, Pages 299-309]
Collagen Alpha-pinene ameliorates liver fibrosis by suppressing oxidative stress, inflammation, and the TGF-β/Smad3 signaling pathway [Volume 28, Issue 4, 2025, Pages 451-460]
Colorectal cancer Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer [Volume 28, Issue 5, 2025, Pages 592-601]
Colorectal Neoplasms Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice [Volume 28, Issue 5, 2025, Pages 584-591]
Computational biology Bioinformatics analysis identifies dysregulation of MiR-548F-3p and its hub gene in triple-negative breast cancer [Volume 28, Issue 4, 2025, Pages 434-443]
Cortical granules Effects of pentoxifylline on mouse oocytes maturation and qualityin vitro [Volume 28, Issue 3, 2025, Pages 310-315]
COTI-2 COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway [Volume 28, Issue 3, 2025, Pages 340-346]
Creatinine Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats [Volume 28, Issue 1, 2025, Pages 56-62]
Curcumin Curcumin exerts protective effects against valproic acid-induced testicular damage through modulating the JAK1/STAT–3/IL–6 signaling pathway in rats [Volume 28, Issue 2, 2025, Pages 230-236]
Cyclophosphamide Sinapic acid attenuated nephrotoxicity against Cyclophosphamide in mice model: A histochemical, immunohistochemical and histopathological evaluation [Volume 28, Issue 5, 2025, Pages 655-661]
Cytokines Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice [Volume 28, Issue 5, 2025, Pages 584-591]
Cytokines Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats [Volume 28, Issue 4, 2025, Pages 461-468]

D

Dendritic cells Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice [Volume 28, Issue 5, 2025, Pages 584-591]
Depression Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression [Volume 28, Issue 4, 2025, Pages 493-497]
Deprivation Protective effect of Lavandula angustifolia essential oil inhalation on neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation [Volume 28, Issue 2, 2025, Pages 264-272]
Diabetes Complications Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vascular complications [Volume 28, Issue 1, 2025, Pages 98-104]
Diabetes Mellitus Effects of different pre-conditioning exercise on leptin synthesis and its downstream signalling pathway in T2DM rats [Volume 28, Issue 1, 2025, Pages 31-37]
Diabetes Mellitus Pim3 up-regulation by YY1 contributes to diabetes-induced cardiac hypertrophy and heart failure [Volume 28, Issue 2, 2025, Pages 245-253]
Diabetes Mellitus Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats [Volume 28, Issue 4, 2025, Pages 461-468]
Diabetes mellitus type 2 Vanillic acid as a promising intervention for metabolic syndrome: Preclinical studies [Volume 28, Issue 2, 2025, Pages 141-150]
Diclofenac Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways [Volume 28, Issue 4, 2025, Pages 507-515]
Dietary supplements Endurance training and pyruvate dehydrogenase kinase 4 (PDK4) inhibition combination is superior to each one alone in attenuating hyperketonemia/ketoacidosis in diabetic rats [Volume 28, Issue 1, 2025, Pages 80-86]
Dietary supplements Dietary supplements for prevention of Alzheimer’s disease: In vivo and in silico molecular docking studies [Volume 28, Issue 2, 2025, Pages 170-180]
Dipeptidyl peptidase 8 Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin [Volume 28, Issue 4, 2025, Pages 516-526]
Dipeptidyl peptidase 9 Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin [Volume 28, Issue 4, 2025, Pages 516-526]
DLL4 Hydroxytyrosol protects isoproterenol-induced myocardial infarction through activating notch signaling [Volume 28, Issue 2, 2025, Pages 217-223]
DNAsome Nanomolecular silencing of TSC22D4 mRNA via a DNAsome-siRNA for enhancing insulin sensitization in hepatocytes [Volume 28, Issue 3, 2025, Pages 385-392]
Drug Delivery Nanoformulation innovations: Revolutionizing precision in migraine therapy [Volume 28, Issue 1, 2025, Pages 16-30]
Drug resistance Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword [Volume 28, Issue 1, 2025, Pages 3-15]

E

EGFR Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma [Volume 28, Issue 1, 2025, Pages 113-120]
Ellagic acid Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury [Volume 28, Issue 1, 2025, Pages 105-112]
Ellagic acid Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression [Volume 28, Issue 4, 2025, Pages 493-497]
Endometrial neoplasms Lysyl oxidase-like 2 promotes the survival, migration, and ferroptosis of endometrial cancer cells by activating the phosphoinositide 3-kinase/protein kinase B pathway [Volume 28, Issue 1, 2025, Pages 72-79]
Endometriosis Simultaneous effect of naringenin and beta-catenin signaling inhibitor C-82 on modulating gene expression and functional pattern of mesenchymal stem cells from endometriosis patients [Volume 28, Issue 5, 2025, Pages 671-679]
Endoplasmic reticulum stress Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways [Volume 28, Issue 4, 2025, Pages 507-515]
Endoplasmic reticulum- stress Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway [Volume 28, Issue 2, 2025, Pages 187-193]
Endoplasmic reticulum- stress Cardiotoxicity caused by acrylamide in rats can be alleviated as a result of suppression of oxidative stress, endoplasmic reticulum stress, inflammation, and apoptosis by morin treatment [Volume 28, Issue 3, 2025, Pages 376-384]
Endurance Exercise Endurance training promotes the browning of WAT by enhancing the NPFF pathway in the hypothalamus in rats with type 2 diabetes [Volume 28, Issue 5, 2025, Pages 575-583]
Endurance training Endurance training and pyruvate dehydrogenase kinase 4 (PDK4) inhibition combination is superior to each one alone in attenuating hyperketonemia/ketoacidosis in diabetic rats [Volume 28, Issue 1, 2025, Pages 80-86]
Energy metabolism SIRT5 prevents mitochondrial dysfunction and cardiac hypertrophy induced by RIP140 [Volume 28, Issue 4, 2025, Pages 477-485]
Epididymis Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis [Volume 28, Issue 2, 2025, Pages 209-216]
Epithelial-mesenchymal transition Melittin alleviates bleomycin-induced pulmonary fibrosis in vivo through regulating TGF-β1/Smad2/3 and AMPK/SIRT1/PGC-1α signaling pathways [Volume 28, Issue 4, 2025, Pages 426-433]
Epithelial sodium channel Role of ENaC in gender-associated differences in blood pressure [Volume 28, Issue 4, 2025, Pages 527-532]
ERK/cyclin D1/p-Smad3L - signaling Tanshinone IIA alleviates liver fibrosis by suppressing hepatic stellate cell proliferation via ERK/cyclin D1/p-Smad3L signaling axis [Volume 28, Issue 5, 2025, Pages 638-646]
ER stress Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats [Volume 28, Issue 3, 2025, Pages 323-331]
Estradiol valerate Comparing the effect of plasma therapy with estradiol valerate in motor and cognitive behavioral disorders in ovariectomized old rats: Behavioral, biochemical, and protein expression [Volume 28, Issue 3, 2025, Pages 366-375]
Exosome Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice [Volume 28, Issue 4, 2025, Pages 469-476]
Extracellular matrix- degradation The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration [Volume 28, Issue 3, 2025, Pages 393-400]

F

Fluorouracil Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats [Volume 28, Issue 5, 2025, Pages 565-574]
Functional recovery Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery [Volume 28, Issue 5, 2025, Pages 627-637]

G

Garcinia kola Ethanol extract of Garcinia kola seeds alleviates HGHFD/STZ-induced nonalcoholic fatty liver disease in diabetic rats by modulating oxidative stress, inflammation, and lipid accumulation [Volume 28, Issue 5, 2025, Pages 662-670]
GBM Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway [Volume 28, Issue 4, 2025, Pages 401-408]
Gene expression Endurance training and pyruvate dehydrogenase kinase 4 (PDK4) inhibition combination is superior to each one alone in attenuating hyperketonemia/ketoacidosis in diabetic rats [Volume 28, Issue 1, 2025, Pages 80-86]
Gene expression Dietary supplements for prevention of Alzheimer’s disease: In vivo and in silico molecular docking studies [Volume 28, Issue 2, 2025, Pages 170-180]
Gene expression Meloxicam mitigated methylglyoxal-induced glycative stress in rats [Volume 28, Issue 5, 2025, Pages 647-654]
Gene expression profiling Bioinformatics analysis identifies dysregulation of MiR-548F-3p and its hub gene in triple-negative breast cancer [Volume 28, Issue 4, 2025, Pages 434-443]
Gene expression profiling Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer [Volume 28, Issue 5, 2025, Pages 592-601]
Glioblastoma Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword [Volume 28, Issue 1, 2025, Pages 3-15]
Glioblastoma Synergistic effect of cold atmospheric plasma and methylene blue loaded nano micelles on treating human glioblastoma cells: An in vitro and molecular dynamics study [Volume 28, Issue 3, 2025, Pages 299-309]
Glioma Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword [Volume 28, Issue 1, 2025, Pages 3-15]
Glucocorticoid Effect of thymoquinone on vitamin D metabolism in glucocorticoid-induced insulin resistance [Volume 28, Issue 3, 2025, Pages 292-298]
Glucose Vanillic acid as a promising intervention for metabolic syndrome: Preclinical studies [Volume 28, Issue 2, 2025, Pages 141-150]
Glutamate Glutamate receptors within the lateral periaqueductal gray (lPAG): Effects on blood pressure and heart rate in basic and hypotensive hemorrhagic rats [Volume 28, Issue 4, 2025, Pages 486-492]
Glutamic acid Scopolamine-induced memory impairment in mice: Soursop leaf extract and fractions protect the hippocampus and prefrontal cortex [Volume 28, Issue 3, 2025, Pages 355-365]
Glutaraldehyde Regeneration of the skin wound by two different crosslinkers: In vitro and in vivo studies [Volume 28, Issue 2, 2025, Pages 194-208]
Glutathione Alpha-pinene ameliorates liver fibrosis by suppressing oxidative stress, inflammation, and the TGF-β/Smad3 signaling pathway [Volume 28, Issue 4, 2025, Pages 451-460]
Glycation Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vascular complications [Volume 28, Issue 1, 2025, Pages 98-104]
Glycation Meloxicam mitigated methylglyoxal-induced glycative stress in rats [Volume 28, Issue 5, 2025, Pages 647-654]
Glycine max Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats [Volume 28, Issue 1, 2025, Pages 56-62]
Glyoxalase-I Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vascular complications [Volume 28, Issue 1, 2025, Pages 98-104]
Granulocyte-macrophage - colony-stimulating factor Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice [Volume 28, Issue 5, 2025, Pages 584-591]

H

Heat Shock Protein Potential therapeutic effects of shrimp protein hydrolysates on NAFLD-induced infertility disorders: Insights into redox balance, heat shock protein expression, and chromatin compaction in male rats [Volume 28, Issue 2, 2025, Pages 158-169]
Hemorrhage Glutamate receptors within the lateral periaqueductal gray (lPAG): Effects on blood pressure and heart rate in basic and hypotensive hemorrhagic rats [Volume 28, Issue 4, 2025, Pages 486-492]
Hepatic stellate cells Tanshinone IIA alleviates liver fibrosis by suppressing hepatic stellate cell proliferation via ERK/cyclin D1/p-Smad3L signaling axis [Volume 28, Issue 5, 2025, Pages 638-646]
HepG2 Nanomolecular silencing of TSC22D4 mRNA via a DNAsome-siRNA for enhancing insulin sensitization in hepatocytes [Volume 28, Issue 3, 2025, Pages 385-392]
HepG2 Ethanol extract of Garcinia kola seeds alleviates HGHFD/STZ-induced nonalcoholic fatty liver disease in diabetic rats by modulating oxidative stress, inflammation, and lipid accumulation [Volume 28, Issue 5, 2025, Pages 662-670]
Hes1 Hydroxytyrosol protects isoproterenol-induced myocardial infarction through activating notch signaling [Volume 28, Issue 2, 2025, Pages 217-223]
High-intensity interval training Effects of different pre-conditioning exercise on leptin synthesis and its downstream signalling pathway in T2DM rats [Volume 28, Issue 1, 2025, Pages 31-37]
HPV-16-E7d Yavar-70A, a novel water-in-oil adjuvant: A potency study in HPV-16E7d vaccine model [Volume 28, Issue 2, 2025, Pages 224-229]
Hs-CRP Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats [Volume 28, Issue 1, 2025, Pages 56-62]
Hydroxytyrosol Hydroxytyrosol protects isoproterenol-induced myocardial infarction through activating notch signaling [Volume 28, Issue 2, 2025, Pages 217-223]
Hypertension Role of ENaC in gender-associated differences in blood pressure [Volume 28, Issue 4, 2025, Pages 527-532]
Hypothalamus Endurance training promotes the browning of WAT by enhancing the NPFF pathway in the hypothalamus in rats with type 2 diabetes [Volume 28, Issue 5, 2025, Pages 575-583]

I

IFN-γ Yavar-70A, a novel water-in-oil adjuvant: A potency study in HPV-16E7d vaccine model [Volume 28, Issue 2, 2025, Pages 224-229]
Immune response Protective immune response induced by cationic liposomes bearing soluble antigens improves the survival of BALB/c mice against Toxoplasma gondii RH strain [Volume 28, Issue 3, 2025, Pages 347-354]
Immunity Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice [Volume 28, Issue 5, 2025, Pages 584-591]
Immunomodulation Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice [Volume 28, Issue 4, 2025, Pages 469-476]
Immunotherapy Role of bacteria in cancers and their therapeutic potential: Review of current knowledge [Volume 28, Issue 3, 2025, Pages 273-282]
Infertility Potential therapeutic effects of shrimp protein hydrolysates on NAFLD-induced infertility disorders: Insights into redox balance, heat shock protein expression, and chromatin compaction in male rats [Volume 28, Issue 2, 2025, Pages 158-169]
Inflammation Rosmarinic acid attenuated inflammation and apoptosis in folic acid-induced renal injury: Role of FoxO3/ NFκB pathway [Volume 28, Issue 3, 2025, Pages 316-322]
Inflammation Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury [Volume 28, Issue 1, 2025, Pages 105-112]
Inflammation Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats [Volume 28, Issue 3, 2025, Pages 323-331]
Inflammation Alpha-pinene ameliorates liver fibrosis by suppressing oxidative stress, inflammation, and the TGF-β/Smad3 signaling pathway [Volume 28, Issue 4, 2025, Pages 451-460]
Inflammation Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways [Volume 28, Issue 4, 2025, Pages 507-515]
Inflammation Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats [Volume 28, Issue 5, 2025, Pages 612-619]
Inflammation Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats [Volume 28, Issue 4, 2025, Pages 461-468]
Inflammation Simultaneous effect of naringenin and beta-catenin signaling inhibitor C-82 on modulating gene expression and functional pattern of mesenchymal stem cells from endometriosis patients [Volume 28, Issue 5, 2025, Pages 671-679]
Inflammatory factors Intervertebral disc degeneration The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration [Volume 28, Issue 3, 2025, Pages 393-400]
Inflammatory mediators Scopolamine-induced memory impairment in mice: Soursop leaf extract and fractions protect the hippocampus and prefrontal cortex [Volume 28, Issue 3, 2025, Pages 355-365]
Inflammatory - osteoclastogenesis Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin [Volume 28, Issue 4, 2025, Pages 516-526]
Innate lymphoid cells Infiltration of innate and adoptive lymphoid cells in 4T1 and MC4-L2 breast cancer models [Volume 28, Issue 1, 2025, Pages 63-71]
Interleukin–6 Curcumin exerts protective effects against valproic acid-induced testicular damage through modulating the JAK1/STAT–3/IL–6 signaling pathway in rats [Volume 28, Issue 2, 2025, Pages 230-236]
In vitro models In vitro effects of phytochemicals on adipogenesis with a focus on molecular mechanisms: A systematic review [Volume 28, Issue 4, 2025, Pages 409-425]

J

Janus kinases Curcumin exerts protective effects against valproic acid-induced testicular damage through modulating the JAK1/STAT–3/IL–6 signaling pathway in rats [Volume 28, Issue 2, 2025, Pages 230-236]

K

Ketamine NMDA receptors antagonists alleviated the acute phase of traumatic brain injury [Volume 28, Issue 2, 2025, Pages 181-186]
Ketone bodies Endurance training and pyruvate dehydrogenase kinase 4 (PDK4) inhibition combination is superior to each one alone in attenuating hyperketonemia/ketoacidosis in diabetic rats [Volume 28, Issue 1, 2025, Pages 80-86]
Kidney Injury Rosmarinic acid attenuated inflammation and apoptosis in folic acid-induced renal injury: Role of FoxO3/ NFκB pathway [Volume 28, Issue 3, 2025, Pages 316-322]

L

Lateral periaqueductal gray Glutamate receptors within the lateral periaqueductal gray (lPAG): Effects on blood pressure and heart rate in basic and hypotensive hemorrhagic rats [Volume 28, Issue 4, 2025, Pages 486-492]
Lavender oil Protective effect of Lavandula angustifolia essential oil inhalation on neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation [Volume 28, Issue 2, 2025, Pages 264-272]
Learning Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats [Volume 28, Issue 3, 2025, Pages 283-291]
Leishmania major In vitro and in vivo evaluation of photo-induced antileishmanial activity of indocyanine green-loaded nanomicelles [Volume 28, Issue 4, 2025, Pages 498-506]
Leptin Effects of different pre-conditioning exercise on leptin synthesis and its downstream signalling pathway in T2DM rats [Volume 28, Issue 1, 2025, Pages 31-37]
Lipid accumulation Ethanol extract of Garcinia kola seeds alleviates HGHFD/STZ-induced nonalcoholic fatty liver disease in diabetic rats by modulating oxidative stress, inflammation, and lipid accumulation [Volume 28, Issue 5, 2025, Pages 662-670]
Lipid metabolism Effects of different pre-conditioning exercise on leptin synthesis and its downstream signalling pathway in T2DM rats [Volume 28, Issue 1, 2025, Pages 31-37]
Lipid metabolism Vanillic acid as a promising intervention for metabolic syndrome: Preclinical studies [Volume 28, Issue 2, 2025, Pages 141-150]
Lipopolysaccharide Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats [Volume 28, Issue 3, 2025, Pages 323-331]
Lipopolysaccharide Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: An overview [Volume 28, Issue 5, 2025, Pages 553-564]
Liver fibrosis Tanshinone IIA alleviates liver fibrosis by suppressing hepatic stellate cell proliferation via ERK/cyclin D1/p-Smad3L signaling axis [Volume 28, Issue 5, 2025, Pages 638-646]
Liver neoplasms Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice [Volume 28, Issue 5, 2025, Pages 584-591]
Locus coeruleus Protective effect of Lavandula angustifolia essential oil inhalation on neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation [Volume 28, Issue 2, 2025, Pages 264-272]
Long noncoding RNA RP11-109D20.2 Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer [Volume 28, Issue 5, 2025, Pages 592-601]
LOXL2 protein Lysyl oxidase-like 2 promotes the survival, migration, and ferroptosis of endometrial cancer cells by activating the phosphoinositide 3-kinase/protein kinase B pathway [Volume 28, Issue 1, 2025, Pages 72-79]
Lung injury Effect of the S100A9/AMPK pathway on PM2.5-mediated mouse lung injury [Volume 28, Issue 1, 2025, Pages 121-129]
Lycopene Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats [Volume 28, Issue 4, 2025, Pages 461-468]
Lysine-deficient protein - kinase Role of ENaC in gender-associated differences in blood pressure [Volume 28, Issue 4, 2025, Pages 527-532]

M

M1 macrophage Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin [Volume 28, Issue 4, 2025, Pages 516-526]
MC4-L2 Infiltration of innate and adoptive lymphoid cells in 4T1 and MC4-L2 breast cancer models [Volume 28, Issue 1, 2025, Pages 63-71]
Melatonin Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis [Volume 28, Issue 2, 2025, Pages 209-216]
Melittin Melittin alleviates bleomycin-induced pulmonary fibrosis in vivo through regulating TGF-β1/Smad2/3 and AMPK/SIRT1/PGC-1α signaling pathways [Volume 28, Issue 4, 2025, Pages 426-433]
Meloxicam Meloxicam mitigated methylglyoxal-induced glycative stress in rats [Volume 28, Issue 5, 2025, Pages 647-654]
Memantine NMDA receptors antagonists alleviated the acute phase of traumatic brain injury [Volume 28, Issue 2, 2025, Pages 181-186]
Membranous nephropathy Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis [Volume 28, Issue 2, 2025, Pages 237-244]
Memory Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats [Volume 28, Issue 3, 2025, Pages 283-291]
Mesenchymal stem cells Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice [Volume 28, Issue 4, 2025, Pages 469-476]
Mesenchymal stem cells Simultaneous effect of naringenin and beta-catenin signaling inhibitor C-82 on modulating gene expression and functional pattern of mesenchymal stem cells from endometriosis patients [Volume 28, Issue 5, 2025, Pages 671-679]
Metabolism Effect of thymoquinone on vitamin D metabolism in glucocorticoid-induced insulin resistance [Volume 28, Issue 3, 2025, Pages 292-298]
Methylene blue Synergistic effect of cold atmospheric plasma and methylene blue loaded nano micelles on treating human glioblastoma cells: An in vitro and molecular dynamics study [Volume 28, Issue 3, 2025, Pages 299-309]
Methylglyoxal Meloxicam mitigated methylglyoxal-induced glycative stress in rats [Volume 28, Issue 5, 2025, Pages 647-654]
Mice Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice [Volume 28, Issue 4, 2025, Pages 469-476]
Microbiota Role of bacteria in cancers and their therapeutic potential: Review of current knowledge [Volume 28, Issue 3, 2025, Pages 273-282]
Middle cerebral artery occlusion/reperfusion Effect of anemoside B4 on ameliorating cerebral ischemic/reperfusion injury [Volume 28, Issue 1, 2025, Pages 49-55]
Migraine Nanoformulation innovations: Revolutionizing precision in migraine therapy [Volume 28, Issue 1, 2025, Pages 16-30]
MiR-448 Apigenin attenuates myocardial ischemia-reperfusion injury through miR-448/SIRT1 axis [Volume 28, Issue 5, 2025, Pages 602-611]
Mitochondria Effects of combo therapy with coenzyme Q10 and mitochondrial transplantation on myocardial ischemia/reperfusion-induced arrhythmias in aged rats [Volume 28, Issue 1, 2025, Pages 38-48]
Mitochondria Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice [Volume 28, Issue 1, 2025, Pages 87-97]
Mitochondria Melittin alleviates bleomycin-induced pulmonary fibrosis in vivo through regulating TGF-β1/Smad2/3 and AMPK/SIRT1/PGC-1α signaling pathways [Volume 28, Issue 4, 2025, Pages 426-433]
Mitochondria SIRT5 prevents mitochondrial dysfunction and cardiac hypertrophy induced by RIP140 [Volume 28, Issue 4, 2025, Pages 477-485]
Molecular docking Dietary supplements for prevention of Alzheimer’s disease: In vivo and in silico molecular docking studies [Volume 28, Issue 2, 2025, Pages 170-180]
Molecular dynamics - Simulation Synergistic effect of cold atmospheric plasma and methylene blue loaded nano micelles on treating human glioblastoma cells: An in vitro and molecular dynamics study [Volume 28, Issue 3, 2025, Pages 299-309]
Molecular mechanism In vitro effects of phytochemicals on adipogenesis with a focus on molecular mechanisms: A systematic review [Volume 28, Issue 4, 2025, Pages 409-425]
Morin Cardiotoxicity caused by acrylamide in rats can be alleviated as a result of suppression of oxidative stress, endoplasmic reticulum stress, inflammation, and apoptosis by morin treatment [Volume 28, Issue 3, 2025, Pages 376-384]
Morin Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways [Volume 28, Issue 4, 2025, Pages 507-515]
Motor Comparing the effect of plasma therapy with estradiol valerate in motor and cognitive behavioral disorders in ovariectomized old rats: Behavioral, biochemical, and protein expression [Volume 28, Issue 3, 2025, Pages 366-375]
Myocardial infarction Hydroxytyrosol protects isoproterenol-induced myocardial infarction through activating notch signaling [Volume 28, Issue 2, 2025, Pages 217-223]
Myocardial ischemia/reperfusion injury Effects of combo therapy with coenzyme Q10 and mitochondrial transplantation on myocardial ischemia/reperfusion-induced arrhythmias in aged rats [Volume 28, Issue 1, 2025, Pages 38-48]

N

NAFLD Potential therapeutic effects of shrimp protein hydrolysates on NAFLD-induced infertility disorders: Insights into redox balance, heat shock protein expression, and chromatin compaction in male rats [Volume 28, Issue 2, 2025, Pages 158-169]
Naloxone Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats [Volume 28, Issue 3, 2025, Pages 283-291]
Nanocapsules Nanoformulation innovations: Revolutionizing precision in migraine therapy [Volume 28, Issue 1, 2025, Pages 16-30]
Nanoformulation Nanoformulation innovations: Revolutionizing precision in migraine therapy [Volume 28, Issue 1, 2025, Pages 16-30]
Nanomedicine In vitro and in vivo evaluation of photo-induced antileishmanial activity of indocyanine green-loaded nanomicelles [Volume 28, Issue 4, 2025, Pages 498-506]
Nanoparticles Nanoformulation innovations: Revolutionizing precision in migraine therapy [Volume 28, Issue 1, 2025, Pages 16-30]
Nanotechnology Nanoformulation innovations: Revolutionizing precision in migraine therapy [Volume 28, Issue 1, 2025, Pages 16-30]
Nanozyme Advancing cancer treatment with nanozyme frameworks: Integrating photothermal, photodynamic, sonodynamic, and chemodynamic therapies [Volume 28, Issue 5, 2025, Pages 533-552]
Neoplasms Role of bacteria in cancers and their therapeutic potential: Review of current knowledge [Volume 28, Issue 3, 2025, Pages 273-282]
Nephrotoxicity Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats [Volume 28, Issue 5, 2025, Pages 565-574]
Nephrotoxicity Sinapic acid attenuated nephrotoxicity against Cyclophosphamide in mice model: A histochemical, immunohistochemical and histopathological evaluation [Volume 28, Issue 5, 2025, Pages 655-661]
Neural Protection Protective effect of Lavandula angustifolia essential oil inhalation on neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation [Volume 28, Issue 2, 2025, Pages 264-272]
Neuroinflammation NMDA receptors antagonists alleviated the acute phase of traumatic brain injury [Volume 28, Issue 2, 2025, Pages 181-186]
Neuroinflammation Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: An overview [Volume 28, Issue 5, 2025, Pages 553-564]
Neuropeptide FF Endurance training promotes the browning of WAT by enhancing the NPFF pathway in the hypothalamus in rats with type 2 diabetes [Volume 28, Issue 5, 2025, Pages 575-583]
Neuroprotective Pre- and post-traumatic boric acid therapy prevents oxidative stress-mediated neuronal apoptosis in spinal cord injury [Volume 28, Issue 4, 2025, Pages 444-450]
NF-kappa β Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vascular complications [Volume 28, Issue 1, 2025, Pages 98-104]
NF- kB Sinapic acid attenuated nephrotoxicity against Cyclophosphamide in mice model: A histochemical, immunohistochemical and histopathological evaluation [Volume 28, Issue 5, 2025, Pages 655-661]
Niacin Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vascular complications [Volume 28, Issue 1, 2025, Pages 98-104]
NLRP6 inflammasome Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury [Volume 28, Issue 1, 2025, Pages 105-112]
NMDA receptor antagonist NMDA receptors antagonists alleviated the acute phase of traumatic brain injury [Volume 28, Issue 2, 2025, Pages 181-186]
Noncoding RNA Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword [Volume 28, Issue 1, 2025, Pages 3-15]
Non-NMDA receptor Glutamate receptors within the lateral periaqueductal gray (lPAG): Effects on blood pressure and heart rate in basic and hypotensive hemorrhagic rats [Volume 28, Issue 4, 2025, Pages 486-492]
Notch1 Hydroxytyrosol protects isoproterenol-induced myocardial infarction through activating notch signaling [Volume 28, Issue 2, 2025, Pages 217-223]
Nrf2/HO-1 pathway Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway [Volume 28, Issue 2, 2025, Pages 187-193]

O

Obesity Vanillic acid as a promising intervention for metabolic syndrome: Preclinical studies [Volume 28, Issue 2, 2025, Pages 141-150]
Obesity In vitro effects of phytochemicals on adipogenesis with a focus on molecular mechanisms: A systematic review [Volume 28, Issue 4, 2025, Pages 409-425]
Obstructive jaundice Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice [Volume 28, Issue 1, 2025, Pages 87-97]
OGD/R Apigenin attenuates myocardial ischemia-reperfusion injury through miR-448/SIRT1 axis [Volume 28, Issue 5, 2025, Pages 602-611]
Oil adjuvants Yavar-70A, a novel water-in-oil adjuvant: A potency study in HPV-16E7d vaccine model [Volume 28, Issue 2, 2025, Pages 224-229]
Oocyte maturation Effects of pentoxifylline on mouse oocytes maturation and qualityin vitro [Volume 28, Issue 3, 2025, Pages 310-315]
Ovariectomy Comparing the effect of plasma therapy with estradiol valerate in motor and cognitive behavioral disorders in ovariectomized old rats: Behavioral, biochemical, and protein expression [Volume 28, Issue 3, 2025, Pages 366-375]
Oxidative stress Effects of combo therapy with coenzyme Q10 and mitochondrial transplantation on myocardial ischemia/reperfusion-induced arrhythmias in aged rats [Volume 28, Issue 1, 2025, Pages 38-48]
Oxidative stress Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vascular complications [Volume 28, Issue 1, 2025, Pages 98-104]
Oxidative stress Potential therapeutic effects of shrimp protein hydrolysates on NAFLD-induced infertility disorders: Insights into redox balance, heat shock protein expression, and chromatin compaction in male rats [Volume 28, Issue 2, 2025, Pages 158-169]
Oxidative stress NMDA receptors antagonists alleviated the acute phase of traumatic brain injury [Volume 28, Issue 2, 2025, Pages 181-186]
Oxidative stress Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis [Volume 28, Issue 2, 2025, Pages 237-244]
Oxidative stress The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration [Volume 28, Issue 3, 2025, Pages 393-400]
Oxidative stress Melittin alleviates bleomycin-induced pulmonary fibrosis in vivo through regulating TGF-β1/Smad2/3 and AMPK/SIRT1/PGC-1α signaling pathways [Volume 28, Issue 4, 2025, Pages 426-433]
Oxidative stress Pre- and post-traumatic boric acid therapy prevents oxidative stress-mediated neuronal apoptosis in spinal cord injury [Volume 28, Issue 4, 2025, Pages 444-450]
Oxidative stress Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways [Volume 28, Issue 4, 2025, Pages 507-515]
Oxidative stress Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats [Volume 28, Issue 5, 2025, Pages 612-619]
Oxidative stress Sinapic acid attenuated nephrotoxicity against Cyclophosphamide in mice model: A histochemical, immunohistochemical and histopathological evaluation [Volume 28, Issue 5, 2025, Pages 655-661]
Oxygen-glucose-deprivation/re-oxygenation Effect of anemoside B4 on ameliorating cerebral ischemic/reperfusion injury [Volume 28, Issue 1, 2025, Pages 49-55]

P

Pain Rutin attenuates complete Freund’s adjuvant-induced inflammatory pain in rats [Volume 28, Issue 3, 2025, Pages 332-339]
Parkinson’s disease Trans-sodium crocetinate ameliorates Parkinson-like disease caused by bisphenol A through inhibition of apoptosis and reduction of α-synuclein in rats [Volume 28, Issue 2, 2025, Pages 254-263]
Pentoxifylline Effects of pentoxifylline on mouse oocytes maturation and qualityin vitro [Volume 28, Issue 3, 2025, Pages 310-315]
Phenolic acid Vanillic acid as a promising intervention for metabolic syndrome: Preclinical studies [Volume 28, Issue 2, 2025, Pages 141-150]
Phosphorylation Lysyl oxidase-like 2 promotes the survival, migration, and ferroptosis of endometrial cancer cells by activating the phosphoinositide 3-kinase/protein kinase B pathway [Volume 28, Issue 1, 2025, Pages 72-79]
Photochemotherapy Synergistic effect of cold atmospheric plasma and methylene blue loaded nano micelles on treating human glioblastoma cells: An in vitro and molecular dynamics study [Volume 28, Issue 3, 2025, Pages 299-309]
Photodynamic Advancing cancer treatment with nanozyme frameworks: Integrating photothermal, photodynamic, sonodynamic, and chemodynamic therapies [Volume 28, Issue 5, 2025, Pages 533-552]
Photodynamic Therapy (PDT) In vitro and in vivo evaluation of photo-induced antileishmanial activity of indocyanine green-loaded nanomicelles [Volume 28, Issue 4, 2025, Pages 498-506]
Photosensitizer In vitro and in vivo evaluation of photo-induced antileishmanial activity of indocyanine green-loaded nanomicelles [Volume 28, Issue 4, 2025, Pages 498-506]
Photothermal Advancing cancer treatment with nanozyme frameworks: Integrating photothermal, photodynamic, sonodynamic, and chemodynamic therapies [Volume 28, Issue 5, 2025, Pages 533-552]
Photothermal therapy (PTT) In vitro and in vivo evaluation of photo-induced antileishmanial activity of indocyanine green-loaded nanomicelles [Volume 28, Issue 4, 2025, Pages 498-506]
Phytochemicals In vitro effects of phytochemicals on adipogenesis with a focus on molecular mechanisms: A systematic review [Volume 28, Issue 4, 2025, Pages 409-425]
Phytoestrogen Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats [Volume 28, Issue 1, 2025, Pages 56-62]
PI3K Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma [Volume 28, Issue 1, 2025, Pages 113-120]
PI3K Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression [Volume 28, Issue 4, 2025, Pages 493-497]
PI3K Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway [Volume 28, Issue 4, 2025, Pages 401-408]
PIK3CG Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma [Volume 28, Issue 1, 2025, Pages 113-120]
Plant Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats [Volume 28, Issue 5, 2025, Pages 565-574]
Platelet-rich plasma The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration [Volume 28, Issue 3, 2025, Pages 393-400]
Plinabulin Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma [Volume 28, Issue 1, 2025, Pages 113-120]
PM2.5 Effect of the S100A9/AMPK pathway on PM2.5-mediated mouse lung injury [Volume 28, Issue 1, 2025, Pages 121-129]
Podocyte Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis [Volume 28, Issue 2, 2025, Pages 237-244]
Polycaprolactone Enhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model [Volume 28, Issue 2, 2025, Pages 151-157]
Polydioxanone Enhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model [Volume 28, Issue 2, 2025, Pages 151-157]
Poly l-lactic acid Enhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model [Volume 28, Issue 2, 2025, Pages 151-157]
Preoptic area Protective effect of Lavandula angustifolia essential oil inhalation on neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation [Volume 28, Issue 2, 2025, Pages 264-272]
Proliferation COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway [Volume 28, Issue 3, 2025, Pages 340-346]
Proliferation Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway [Volume 28, Issue 4, 2025, Pages 401-408]
Protein expression Comparing the effect of plasma therapy with estradiol valerate in motor and cognitive behavioral disorders in ovariectomized old rats: Behavioral, biochemical, and protein expression [Volume 28, Issue 3, 2025, Pages 366-375]
Protein hydrolysates Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats [Volume 28, Issue 1, 2025, Pages 56-62]
Protein hydrolysates Potential therapeutic effects of shrimp protein hydrolysates on NAFLD-induced infertility disorders: Insights into redox balance, heat shock protein expression, and chromatin compaction in male rats [Volume 28, Issue 2, 2025, Pages 158-169]
Proviral insertion of- Moloney virus 3 kinase Pim3 up-regulation by YY1 contributes to diabetes-induced cardiac hypertrophy and heart failure [Volume 28, Issue 2, 2025, Pages 245-253]
Puerarin Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway [Volume 28, Issue 2, 2025, Pages 187-193]
Pulmonary Fibrosis Melittin alleviates bleomycin-induced pulmonary fibrosis in vivo through regulating TGF-β1/Smad2/3 and AMPK/SIRT1/PGC-1α signaling pathways [Volume 28, Issue 4, 2025, Pages 426-433]
Pyroptosis Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury [Volume 28, Issue 1, 2025, Pages 105-112]
Pyroptosis Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis [Volume 28, Issue 2, 2025, Pages 237-244]
Pyruvate dehydrogenase - kinase 4 Endurance training and pyruvate dehydrogenase kinase 4 (PDK4) inhibition combination is superior to each one alone in attenuating hyperketonemia/ketoacidosis in diabetic rats [Volume 28, Issue 1, 2025, Pages 80-86]

R

Radioresistance Regulatory role of circular RNAs in the development of therapeutic resistance in the glioma: A double-edged sword [Volume 28, Issue 1, 2025, Pages 3-15]
Rat Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats [Volume 28, Issue 3, 2025, Pages 323-331]
RAW264.7 cells Targeting dipeptidyl peptidase-8/9 to combat inflammation-induced osteoclastogenesis in RAW264.7 macrophages and analysis of anti-osteoclastogenesis potential of chrysin [Volume 28, Issue 4, 2025, Pages 516-526]
Reactive Oxygen Species Effects of pentoxifylline on mouse oocytes maturation and qualityin vitro [Volume 28, Issue 3, 2025, Pages 310-315]
Reactive Oxygen Species Synergistic effect of cold atmospheric plasma and methylene blue loaded nano micelles on treating human glioblastoma cells: An in vitro and molecular dynamics study [Volume 28, Issue 3, 2025, Pages 299-309]
Regeneration Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice [Volume 28, Issue 4, 2025, Pages 469-476]
Renal ischemia/reperfusion- injury Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway [Volume 28, Issue 2, 2025, Pages 187-193]
Resins Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats [Volume 28, Issue 5, 2025, Pages 565-574]
Respiratory System Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats [Volume 28, Issue 3, 2025, Pages 323-331]
RGD motif Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats [Volume 28, Issue 1, 2025, Pages 56-62]
Rheumatoid arthritis Rutin attenuates complete Freund’s adjuvant-induced inflammatory pain in rats [Volume 28, Issue 3, 2025, Pages 332-339]
RIP140 SIRT5 prevents mitochondrial dysfunction and cardiac hypertrophy induced by RIP140 [Volume 28, Issue 4, 2025, Pages 477-485]
RNA sequencing analysis Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer [Volume 28, Issue 5, 2025, Pages 592-601]
ROS Effect of the S100A9/AMPK pathway on PM2.5-mediated mouse lung injury [Volume 28, Issue 1, 2025, Pages 121-129]
Rosmarinic acid Rosmarinic acid attenuated inflammation and apoptosis in folic acid-induced renal injury: Role of FoxO3/ NFκB pathway [Volume 28, Issue 3, 2025, Pages 316-322]
Royal jelly Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats [Volume 28, Issue 5, 2025, Pages 612-619]
Rutin Rutin attenuates complete Freund’s adjuvant-induced inflammatory pain in rats [Volume 28, Issue 3, 2025, Pages 332-339]

S

S100A9 Effect of the S100A9/AMPK pathway on PM2.5-mediated mouse lung injury [Volume 28, Issue 1, 2025, Pages 121-129]
Saffron Trans-sodium crocetinate ameliorates Parkinson-like disease caused by bisphenol A through inhibition of apoptosis and reduction of α-synuclein in rats [Volume 28, Issue 2, 2025, Pages 254-263]
Selegiline Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery [Volume 28, Issue 5, 2025, Pages 627-637]
Sepsis Amantadine reduces sepsis-induced brain injury via NLRP3/caspase-1 inflammasome activation [Volume 28, Issue 5, 2025, Pages 620-626]
Sepsis-associated - encephalopathy Amantadine reduces sepsis-induced brain injury via NLRP3/caspase-1 inflammasome activation [Volume 28, Issue 5, 2025, Pages 620-626]
Sex differences Role of ENaC in gender-associated differences in blood pressure [Volume 28, Issue 4, 2025, Pages 527-532]
Signal transduction Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats [Volume 28, Issue 4, 2025, Pages 461-468]
Sinapic acid Sinapic acid attenuated nephrotoxicity against Cyclophosphamide in mice model: A histochemical, immunohistochemical and histopathological evaluation [Volume 28, Issue 5, 2025, Pages 655-661]
SIRT5 SIRT5 prevents mitochondrial dysfunction and cardiac hypertrophy induced by RIP140 [Volume 28, Issue 4, 2025, Pages 477-485]
Sirtuin1 Echinacoside alleviates Ang II-induced cardiac fibrosis by enhancing the SIRT1/IL-11 pathway [Volume 28, Issue 1, 2025, Pages 130-140]
Sirtuin 2 Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats [Volume 28, Issue 5, 2025, Pages 565-574]
Sirtuin 3 Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats [Volume 28, Issue 5, 2025, Pages 565-574]
Sleep Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats [Volume 28, Issue 3, 2025, Pages 283-291]
Sleep Protective effect of Lavandula angustifolia essential oil inhalation on neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation [Volume 28, Issue 2, 2025, Pages 264-272]
Sonodynamic Advancing cancer treatment with nanozyme frameworks: Integrating photothermal, photodynamic, sonodynamic, and chemodynamic therapies [Volume 28, Issue 5, 2025, Pages 533-552]
Soybean Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats [Volume 28, Issue 1, 2025, Pages 56-62]
Sperm Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis [Volume 28, Issue 2, 2025, Pages 209-216]
Spinal cord injury Pre- and post-traumatic boric acid therapy prevents oxidative stress-mediated neuronal apoptosis in spinal cord injury [Volume 28, Issue 4, 2025, Pages 444-450]
Spinal cord injury Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery [Volume 28, Issue 5, 2025, Pages 627-637]
Spindle apparatus Effects of pentoxifylline on mouse oocytes maturation and qualityin vitro [Volume 28, Issue 3, 2025, Pages 310-315]
Sports Medicine Effects of different pre-conditioning exercise on leptin synthesis and its downstream signalling pathway in T2DM rats [Volume 28, Issue 1, 2025, Pages 31-37]
SREBP-1C Ethanol extract of Garcinia kola seeds alleviates HGHFD/STZ-induced nonalcoholic fatty liver disease in diabetic rats by modulating oxidative stress, inflammation, and lipid accumulation [Volume 28, Issue 5, 2025, Pages 662-670]
SSRI Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats [Volume 28, Issue 3, 2025, Pages 323-331]
Sulforaphane Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis [Volume 28, Issue 2, 2025, Pages 237-244]
Survival Simultaneous effect of naringenin and beta-catenin signaling inhibitor C-82 on modulating gene expression and functional pattern of mesenchymal stem cells from endometriosis patients [Volume 28, Issue 5, 2025, Pages 671-679]
Survival analysis Bioinformatics analysis identifies dysregulation of MiR-548F-3p and its hub gene in triple-negative breast cancer [Volume 28, Issue 4, 2025, Pages 434-443]
Survival rate Protective immune response induced by cationic liposomes bearing soluble antigens improves the survival of BALB/c mice against Toxoplasma gondii RH strain [Volume 28, Issue 3, 2025, Pages 347-354]
Systematic review In vitro effects of phytochemicals on adipogenesis with a focus on molecular mechanisms: A systematic review [Volume 28, Issue 4, 2025, Pages 409-425]

T

T2DM combined with - NAFLD Ethanol extract of Garcinia kola seeds alleviates HGHFD/STZ-induced nonalcoholic fatty liver disease in diabetic rats by modulating oxidative stress, inflammation, and lipid accumulation [Volume 28, Issue 5, 2025, Pages 662-670]
Tanshinone IIA Tanshinone IIA alleviates liver fibrosis by suppressing hepatic stellate cell proliferation via ERK/cyclin D1/p-Smad3L signaling axis [Volume 28, Issue 5, 2025, Pages 638-646]
Testicular damage Curcumin exerts protective effects against valproic acid-induced testicular damage through modulating the JAK1/STAT–3/IL–6 signaling pathway in rats [Volume 28, Issue 2, 2025, Pages 230-236]
Testosterone Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis [Volume 28, Issue 2, 2025, Pages 209-216]
TGF-β1 Tanshinone IIA alleviates liver fibrosis by suppressing hepatic stellate cell proliferation via ERK/cyclin D1/p-Smad3L signaling axis [Volume 28, Issue 5, 2025, Pages 638-646]
Thiamine Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vascular complications [Volume 28, Issue 1, 2025, Pages 98-104]
Thin-layer chromatography Scopolamine-induced memory impairment in mice: Soursop leaf extract and fractions protect the hippocampus and prefrontal cortex [Volume 28, Issue 3, 2025, Pages 355-365]
Thymoquinone Effect of thymoquinone on vitamin D metabolism in glucocorticoid-induced insulin resistance [Volume 28, Issue 3, 2025, Pages 292-298]
Tissue engineering Regeneration of the skin wound by two different crosslinkers: In vitro and in vivo studies [Volume 28, Issue 2, 2025, Pages 194-208]
Toll-like receptor 4 Alpha-pinene ameliorates liver fibrosis by suppressing oxidative stress, inflammation, and the TGF-β/Smad3 signaling pathway [Volume 28, Issue 4, 2025, Pages 451-460]
Toll-like receptors Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: An overview [Volume 28, Issue 5, 2025, Pages 553-564]
Toxoplasma gondii Protective immune response induced by cationic liposomes bearing soluble antigens improves the survival of BALB/c mice against Toxoplasma gondii RH strain [Volume 28, Issue 3, 2025, Pages 347-354]
Transitional protein Potential therapeutic effects of shrimp protein hydrolysates on NAFLD-induced infertility disorders: Insights into redox balance, heat shock protein expression, and chromatin compaction in male rats [Volume 28, Issue 2, 2025, Pages 158-169]
Transplantation Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice [Volume 28, Issue 4, 2025, Pages 469-476]
Traumatic brain injury NMDA receptors antagonists alleviated the acute phase of traumatic brain injury [Volume 28, Issue 2, 2025, Pages 181-186]
Triple negative breast - neoplasms Bioinformatics analysis identifies dysregulation of MiR-548F-3p and its hub gene in triple-negative breast cancer [Volume 28, Issue 4, 2025, Pages 434-443]
TSC22D4 Nanomolecular silencing of TSC22D4 mRNA via a DNAsome-siRNA for enhancing insulin sensitization in hepatocytes [Volume 28, Issue 3, 2025, Pages 385-392]
Tumor Microenvironment Role of bacteria in cancers and their therapeutic potential: Review of current knowledge [Volume 28, Issue 3, 2025, Pages 273-282]
Tumor Microenvironment Synergistic effects of cryoablation and GM-CSF in colorectal liver metastases management in tumor-bearing mice [Volume 28, Issue 5, 2025, Pages 584-591]
Tumor therapy Advancing cancer treatment with nanozyme frameworks: Integrating photothermal, photodynamic, sonodynamic, and chemodynamic therapies [Volume 28, Issue 5, 2025, Pages 533-552]
Type 2 diabetes Endurance training promotes the browning of WAT by enhancing the NPFF pathway in the hypothalamus in rats with type 2 diabetes [Volume 28, Issue 5, 2025, Pages 575-583]

U

UVB Enhancing dermal collagen density towards youthfulness: A comparative study of PCL, PLLA, and PDO thread implantation in aging rats model [Volume 28, Issue 2, 2025, Pages 151-157]

V

Vaccine formulation Yavar-70A, a novel water-in-oil adjuvant: A potency study in HPV-16E7d vaccine model [Volume 28, Issue 2, 2025, Pages 224-229]
Valproic acid Curcumin exerts protective effects against valproic acid-induced testicular damage through modulating the JAK1/STAT–3/IL–6 signaling pathway in rats [Volume 28, Issue 2, 2025, Pages 230-236]
VDAC1 Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice [Volume 28, Issue 1, 2025, Pages 87-97]
Vitamin D Effect of thymoquinone on vitamin D metabolism in glucocorticoid-induced insulin resistance [Volume 28, Issue 3, 2025, Pages 292-298]
Vortioxetine Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway [Volume 28, Issue 4, 2025, Pages 401-408]

Y

Yavar-70A Yavar-70A, a novel water-in-oil adjuvant: A potency study in HPV-16E7d vaccine model [Volume 28, Issue 2, 2025, Pages 224-229]
Yin Yang 1 Pim3 up-regulation by YY1 contributes to diabetes-induced cardiac hypertrophy and heart failure [Volume 28, Issue 2, 2025, Pages 245-253]
Young plasma Comparing the effect of plasma therapy with estradiol valerate in motor and cognitive behavioral disorders in ovariectomized old rats: Behavioral, biochemical, and protein expression [Volume 28, Issue 3, 2025, Pages 366-375]