Iranian Journal of Basic Medical Sciences

Keyword Index

A

A549 cell line Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
Acetaminophen Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inﬂammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
Acupoint catgut embedding Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
Acute Kidney Injuries Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
Acute kidney injury N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
Acute lung injury Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
Acute lung injury Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
Acute lung injury Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates diabetes-induced acute lung injury via activating Nrf2/ HO-1 [Volume 27, Issue 11, 2024, Pages 1423-1429]
Acute lymphoblastic - leukemia (ALL) Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
Acute pancreatitis Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
Acute pancreatitis L-Arginine-induced acute pancreatitis and its associated lung injury in rats: Down-regulation of TLR-4/MAPK-p38/JNK signaling pathway via Ginkgo biloba extract EGb 761 [Volume 27, Issue 8, 2024, Pages 959-966]
Acute renal injury Protective role of alpha-lipoic acid against rhabdomyolysis-induced acute kidney injury in rats [Volume 27, Issue 8, 2024, Pages 1033-1039]
Adipose-derived - mesenchymal stem cells Vitamin C, doxycycline, and azithromycin (VDA) targeted changes in cellular senescence-related genes in human adipose-derived mesenchymal stem cells [Volume 27, Issue 11, 2024, Pages 1380-1388]
Adjuvant Inactivated herpes simplex virus-1 vaccine formulated in aqueous and alcoholic extracts of propolis boosts cellular and IgG responses [Volume 27, Issue 9, 2024, Pages 1209-1213]
Adriamycin Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
ADSCs Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
Age-related macular - degeneration Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
Aging Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
Aging Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
Aging 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
Agmatine Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
Airway smooth muscle Beta-adrenergic receptor stimulation, histamine receptor inhibition, and potassium channel opening contribute to the relaxant effects of crocetin on airway smooth muscle [Volume 27, Issue 10, 2024, Pages 1317-1322]
Akt Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
Akt Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
Alamandine Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
Alcohols Huangqi Gegen decoction ameliorates alcohol-induced cognitive dysfunction via attenuating oxidative stress and enhancing blood-brain barrier integrity in rats through the Keap1-Nrf2/HO-1 signaling pathway [Volume 27, Issue 10, 2024, Pages 1331-1339]
Alginate hydrogel Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
Alpha-lipoic acid Protective role of alpha-lipoic acid against rhabdomyolysis-induced acute kidney injury in rats [Volume 27, Issue 8, 2024, Pages 1033-1039]
Alpha-mangostin Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
Alpha-pinene Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
Alpha-pinene The protective effects of alpha-pinene on high glucose-induced oxidative stress and inflammation in HepG2 cells [Volume 27, Issue 8, 2024, Pages 967-974]
Alveolar epithelial cell Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
Alzheimer disease Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
Alzheimer disease Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes [Volume 27, Issue 10, 2024, Pages 1268-1275]
Alzheimer’s disease Recent advancements in the role of phytochemicals and Medicinal plants in prophylaxis and management of Alzheimer’s disease [Volume 27, Issue 11, 2024, Pages 1357-1369]
Alzheimer’s disease Catalpol alleviates amyloid- generation and neuronal oxidative stress injury via activating the Keap1-Nrf2/ARE signaling pathway in the immortalized lymphocytes from patients with late-onset Alzheimer’s disease and SKNMC cells co-culture model [Volume 27, Issue 12, 2024, Pages 1547-1557]
Alzheimer’s disease High-intensity interval training combined with cannabidiol supplementation improves cognitive impairment by regulating the expression of apolipoprotein E, presenilin-1, and glutamate proteins in a rat model of amyloid β-induced Alzheimer’s disease [Volume 27, Issue 12, 2024, Pages 1583-1591]
AM251 Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
Amiodarone How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
Amnion Injectable multifunctional hydrogel containing Sphingosine 1-phosphate and human acellular amniotic membrane for skin wound healing [Volume 27, Issue 9, 2024, Pages 1134-1147]
AMP-activated protein - kinase Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
Amyloid-beta Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
Amyloid beta-Peptides Catalpol alleviates amyloid- generation and neuronal oxidative stress injury via activating the Keap1-Nrf2/ARE signaling pathway in the immortalized lymphocytes from patients with late-onset Alzheimer’s disease and SKNMC cells co-culture model [Volume 27, Issue 12, 2024, Pages 1547-1557]
Analgesics Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review [Volume 27, Issue 12, 2024, Pages 1492-1505]
Andrographolide Andrographolide demonstrates anti-proliferative activity in oral cancer by promoting apoptosis, the programmed cell death process [Volume 27, Issue 10, 2024, Pages 1300-1308]
Angiogenesis Comparison of different hydroxyapatite composites for bone tissue repair: In vitro and in vivo analyses [Volume 27, Issue 9, 2024, Pages 1155-1161]
Angiogenesis Intravenous administration exosomes derived from human amniotic mesenchymal stem cells improves neurological recovery after acute traumatic spinal cord injury in rats [Volume 27, Issue 10, 2024, Pages 1284-1292]
Angiotensin II Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
Animal model Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
Animal models Taurine supplementation decreases fat accumulation by suppressing FAS and enhancing ATGL through the ATGL pathway [Volume 27, Issue 12, 2024, Pages 1529-1535]
Annulus fibrosus Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
Anti-androgen Effects of lupeol and flutamide on experimentally-induced polycystic ovary syndrome in mice [Volume 27, Issue 8, 2024, Pages 1067-1076]
Anti-arthritic Synthesized diterpene lactone derivative attenuated Freund’s complete adjuvant-induced arthritis in Wistar rats [Volume 27, Issue 9, 2024, Pages 1197-1208]
Antibacterial agents Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
Antibacterial drug resistance Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
Antibiotic resistance Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
Anti-cancer Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
Antihemophilic factor Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
Anti-inflammation Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
Anti-inflammatory Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
Anti-inflammatory Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
Anti-inflammatory Protective role of alpha-lipoic acid against rhabdomyolysis-induced acute kidney injury in rats [Volume 27, Issue 8, 2024, Pages 1033-1039]
Anti-inflammatory agents Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
Anti-inflammatory agents Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review [Volume 27, Issue 12, 2024, Pages 1492-1505]
Anti-metastatic activity In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
Antimicrobial agent Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
Antiobesity Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
Anti-oxidant Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
Anti-oxidant Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
Anti-oxidant Protective role of alpha-lipoic acid against rhabdomyolysis-induced acute kidney injury in rats [Volume 27, Issue 8, 2024, Pages 1033-1039]
Anti-oxidant Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice [Volume 27, Issue 12, 2024, Pages 1515-1528]
Antioxidants Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
Anti-Oxidants Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
Anti-Oxidants Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
Anti-Oxidants Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
Anti-Oxidants Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
Anti-Oxidants Comprehensive and updated review on anti-oxidant effects of Nigella sativa and its constituent, thymoquinone, in various disorders [Volume 27, Issue 8, 2024, Pages 923-951]
Anti-Oxidants Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review [Volume 27, Issue 12, 2024, Pages 1492-1505]
Anti-oxidative Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
Anti-rheumatoid Synthesized diterpene lactone derivative attenuated Freund’s complete adjuvant-induced arthritis in Wistar rats [Volume 27, Issue 9, 2024, Pages 1197-1208]
Anxiety Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
Anxiety Luteolin reversed anxiety and depressive-like behavior via modulation of the NF-κB/NLRP3 inflammasome axis in the hippocampus of rats subjected to sleep deprivation [Volume 27, Issue 8, 2024, Pages 1050-1058]
Apatinib mesylate Apatinib has anti-tumor effects and induces autophagy in lung cancer cells with high expression of VEGFR-2 [Volume 27, Issue 11, 2024, Pages 1370-1379]
Apigenin Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
Apolipoprotein E High-intensity interval training combined with cannabidiol supplementation improves cognitive impairment by regulating the expression of apolipoprotein E, presenilin-1, and glutamate proteins in a rat model of amyloid β-induced Alzheimer’s disease [Volume 27, Issue 12, 2024, Pages 1583-1591]
Apoptosis Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
Apoptosis Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
Apoptosis Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
Apoptosis Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
Apoptosis Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
Apoptosis Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
Apoptosis Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
Apoptosis Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
Apoptosis Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
Apoptosis 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
Apoptosis Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
Apoptosis Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
Apoptosis N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
Apoptosis Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
Apoptosis Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
Apoptosis Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
Apoptosis Stimulating effect of nanocurcumin and crocin on proliferation and pluripotency of bone marrow-derived mesenchymal stem cells [Volume 27, Issue 9, 2024, Pages 1187-1196]
Apoptosis Naringin alleviates gefitinib-induced hepatotoxicity through anti-oxidation, inhibition of apoptosis, and autophagy [Volume 27, Issue 10, 2024, Pages 1309-1316]
Apoptosis Andrographolide demonstrates anti-proliferative activity in oral cancer by promoting apoptosis, the programmed cell death process [Volume 27, Issue 10, 2024, Pages 1300-1308]
Apoptosis C-71980262, A novel small molecule against human papilloma virus-16 E6 (HPV-16 E6) with anticancer potency against cervical cancer: A computational guided in vitro approach [Volume 27, Issue 11, 2024, Pages 1389-1396]
Apoptosis Apatinib has anti-tumor effects and induces autophagy in lung cancer cells with high expression of VEGFR-2 [Volume 27, Issue 11, 2024, Pages 1370-1379]
Apoptosis Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice [Volume 27, Issue 12, 2024, Pages 1515-1528]
Apoptosis Catalpol alleviates amyloid- generation and neuronal oxidative stress injury via activating the Keap1-Nrf2/ARE signaling pathway in the immortalized lymphocytes from patients with late-onset Alzheimer’s disease and SKNMC cells co-culture model [Volume 27, Issue 12, 2024, Pages 1547-1557]
Apoptosis Baicalein blocked gastric cancer cell proliferation and invasion through modulated platelet type 12-lipoxygenase [Volume 27, Issue 12, 2024, Pages 1574-1582]
Apoptosis-inducing factor Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
Apoptotic activity In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
Arrhythmia Antiarrhythmic potentials of irisin in ischemia/reperfusion injury of diabetic rats through modulating mitochondria-endoplasmic reticulum interaction and inhibiting pyroptosis [Volume 27, Issue 11, 2024, Pages 1440-1446]
Arterial Pressure Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
Asthma Crocin from saffron ameliorates allergic airway inflammation through NF-κB, IL-17, and Nrf2/HO-1 signaling pathways in mice [Volume 27, Issue 12, 2024, Pages 1624-1631]
Astrocyte Testosterone signaling pathways for reducing neuropathic pain in a rat model of spinothalamic tract lesion [Volume 27, Issue 11, 2024, Pages 1417-1422]
ATG4B Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
Atglistatin Taurine supplementation decreases fat accumulation by suppressing FAS and enhancing ATGL through the ATGL pathway [Volume 27, Issue 12, 2024, Pages 1529-1535]
Atherosclerosis Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
Atretic follicles Effects of lupeol and flutamide on experimentally-induced polycystic ovary syndrome in mice [Volume 27, Issue 8, 2024, Pages 1067-1076]
Atrial fibrillation Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
Atrial fibrosis Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
Auditory dysfunction Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
Autism Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
Autophagy Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
Autophagy Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
Autophagy Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
Autophagy Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
Autophagy THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
Autophagy Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
Autophagy Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
Autophagy Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
Autophagy Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
Autophagy Naringin alleviates gefitinib-induced hepatotoxicity through anti-oxidation, inhibition of apoptosis, and autophagy [Volume 27, Issue 10, 2024, Pages 1309-1316]
Autophagy Apatinib has anti-tumor effects and induces autophagy in lung cancer cells with high expression of VEGFR-2 [Volume 27, Issue 11, 2024, Pages 1370-1379]
Autophagy Targeting autophagy for breast cancer prevention and therapy: From classical methods to phytochemical agents [Volume 27, Issue 12, 2024, Pages 1475-1491]
Azithromycin Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
Azithromycin Vitamin C, doxycycline, and azithromycin (VDA) targeted changes in cellular senescence-related genes in human adipose-derived mesenchymal stem cells [Volume 27, Issue 11, 2024, Pages 1380-1388]

B

Baicalein Baicalein blocked gastric cancer cell proliferation and invasion through modulated platelet type 12-lipoxygenase [Volume 27, Issue 12, 2024, Pages 1574-1582]
BDNF Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring [Volume 27, Issue 9, 2024, Pages 1115-1123]
Beclin 1 Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
Behavior Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
Bentonite-nanoparticles Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
Bevacizumab Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
Bioactive plant extracts Evaluation of bioactive extract nanoparticles on pulp stem cell behavior relevant to dental care using chemical composition of gelatin-Arabian gum nano polymer [Volume 27, Issue 8, 2024, Pages 975-984]
Biodegradable scaffolds Zinc oxide nanoparticle-reinforced sodium alginate/hydroxyapatite scaffolds for osteoporosis treatment in fragility fracture patients: Development and characterization using artificial neural networks (ANNs) modeling [Volume 27, Issue 12, 2024, Pages 1592-1603]
Biofilm Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
Bioinformatics Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
Bioinformatics analysis Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
Biomarkers Introduction of LPIN1 as a potential diagnostic and prognostic biomarker for gastric cancer via integrative bioinformatics analysis of a competing endogenous RNA network and experimental validation [Volume 27, Issue 11, 2024, Pages 1456-1463]
Blood-brain barrier Huangqi Gegen decoction ameliorates alcohol-induced cognitive dysfunction via attenuating oxidative stress and enhancing blood-brain barrier integrity in rats through the Keap1-Nrf2/HO-1 signaling pathway [Volume 27, Issue 10, 2024, Pages 1331-1339]
Blood urea nitrogen Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
Body mass index Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
Bone Density Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
Bone formation Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system [Volume 27, Issue 10, 2024, Pages 1251-1259]
Box-Behnken design Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
Brain Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
Brain Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
Brain Neuroprotective roles of flavonoid “hispidulin” in the central nervous system: A review [Volume 27, Issue 9, 2024, Pages 1077-1084]
Brain edema Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
Brain injury Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
Brain injury Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
Brain ischemia Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
Breast Cancer Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
Breast Cancer Candidiasis in breast cancer: Tumor progression or not? [Volume 27, Issue 11, 2024, Pages 1346-1356]
Breast Cancer Targeting autophagy for breast cancer prevention and therapy: From classical methods to phytochemical agents [Volume 27, Issue 12, 2024, Pages 1475-1491]
Breast Cancer Doxorubicin-loaded NK exosomes enable cytotoxicity against triple-negative breast cancer spheroids [Volume 27, Issue 12, 2024, Pages 1604-1615]
Breast carcinoma The simultaneous use of CRISPR/Cas9 to knock out the PI3Kca gene with radiation to enhance radiosensitivity and inhibit tumor growth in breast cancer [Volume 27, Issue 12, 2024, Pages 1566-1573]
Broccoli Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]

C

Cadmium Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
Caffeine Effects of dose-dependent chronic caffeine consumption in a rat burn wound model: Histopathological and immunohistochemical evaluation [Volume 27, Issue 9, 2024, Pages 1180-1186]
Calcium oxalate Metabolomics analysis reveals a protective effect of hydroxycitric acid on calcium oxalate-induced kidney injury [Volume 27, Issue 10, 2024, Pages 1243-1250]
Calcium Phosphates Lactosylated lipid calcium phosphate-based nanoparticles: A promising approach for efficient DNA delivery to hepatocytes [Volume 27, Issue 8, 2024, Pages 952-958]
Cancer-selective-cytotoxicity In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
Cancer therapy Candidiasis in breast cancer: Tumor progression or not? [Volume 27, Issue 11, 2024, Pages 1346-1356]
Cancer Treatment Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
Candida albicans Candidiasis in breast cancer: Tumor progression or not? [Volume 27, Issue 11, 2024, Pages 1346-1356]
Cannabidiol High-intensity interval training combined with cannabidiol supplementation improves cognitive impairment by regulating the expression of apolipoprotein E, presenilin-1, and glutamate proteins in a rat model of amyloid β-induced Alzheimer’s disease [Volume 27, Issue 12, 2024, Pages 1583-1591]
Cannabinoid receptors Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
Cannabinoids Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
Cannabinoids Revitalizing polycystic ovary syndrome: The therapeutic impact of low-dose ∆9 tetrahydrocannabinol through reduction of oxidative stress and modulation of macrophage polarization [Volume 27, Issue 8, 2024, Pages 1040-1049]
Capparis spinosa Suppression of TGF-β/Smad3 signaling pathway by Capparis spinosa and quercetin in a rat model of nonalcoholic steatohepatitis [Volume 27, Issue 9, 2024, Pages 1096-1104]
Carbon tetrachloride (CCl4) Resveratrol treatment ameliorates hepatic damage via the TGF-β/SMAD signaling pathway in a phenobarbital/CCl4-induced hepatic fibrosis model [Volume 27, Issue 9, 2024, Pages 1124-1133]
Cardiac fibroblast SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
Cardiac fibrosis SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
Cardiac remodeling Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
Cardiomyocytes Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
Cardioprotection Antiarrhythmic potentials of irisin in ischemia/reperfusion injury of diabetic rats through modulating mitochondria-endoplasmic reticulum interaction and inhibiting pyroptosis [Volume 27, Issue 11, 2024, Pages 1440-1446]
Cardiotoxicity Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
Cardiovascular Disease Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
Carotenoids Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
Caspase-3 Evening primrose oil ameliorates tissue architecture, apoptosis, and oxidative stress in the pancreas of diabetic rats: Possible role of miR-21 [Volume 27, Issue 12, 2024, Pages 1558-1565]
Caspases Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
Catalpol Catalpol alleviates amyloid- generation and neuronal oxidative stress injury via activating the Keap1-Nrf2/ARE signaling pathway in the immortalized lymphocytes from patients with late-onset Alzheimer’s disease and SKNMC cells co-culture model [Volume 27, Issue 12, 2024, Pages 1547-1557]
Catechol-O-methyltransferase (COMT) H9C2 A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]
Cation channels Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
Cecal ligation and puncture Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
Cell cycle Andrographolide demonstrates anti-proliferative activity in oral cancer by promoting apoptosis, the programmed cell death process [Volume 27, Issue 10, 2024, Pages 1300-1308]
Cell damage Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
Cell death Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inﬂammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
Cell death Targeting autophagy for breast cancer prevention and therapy: From classical methods to phytochemical agents [Volume 27, Issue 12, 2024, Pages 1475-1491]
Cell Proliferation Stimulating effect of nanocurcumin and crocin on proliferation and pluripotency of bone marrow-derived mesenchymal stem cells [Volume 27, Issue 9, 2024, Pages 1187-1196]
Cell Proliferation Apatinib has anti-tumor effects and induces autophagy in lung cancer cells with high expression of VEGFR-2 [Volume 27, Issue 11, 2024, Pages 1370-1379]
Cell self renewal Stimulating effect of nanocurcumin and crocin on proliferation and pluripotency of bone marrow-derived mesenchymal stem cells [Volume 27, Issue 9, 2024, Pages 1187-1196]
Cellular senescence (-)-α-Bisabolol inhibits D-Gal-induced HSF cellular senescence in vitro and prevents skin aging in vivo by reducing SASP [Volume 27, Issue 9, 2024, Pages 1105-1114]
Cellular senescence Vitamin C, doxycycline, and azithromycin (VDA) targeted changes in cellular senescence-related genes in human adipose-derived mesenchymal stem cells [Volume 27, Issue 11, 2024, Pages 1380-1388]
Cellular spheroid Doxorubicin-loaded NK exosomes enable cytotoxicity against triple-negative breast cancer spheroids [Volume 27, Issue 12, 2024, Pages 1604-1615]
Cell viability The protective effects of alpha-pinene on high glucose-induced oxidative stress and inflammation in HepG2 cells [Volume 27, Issue 8, 2024, Pages 967-974]
Cell wall Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
Cervical Cancer C-71980262, A novel small molecule against human papilloma virus-16 E6 (HPV-16 E6) with anticancer potency against cervical cancer: A computational guided in vitro approach [Volume 27, Issue 11, 2024, Pages 1389-1396]
Cetirizine Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
Chemical stability Evaluation of bioactive extract nanoparticles on pulp stem cell behavior relevant to dental care using chemical composition of gelatin-Arabian gum nano polymer [Volume 27, Issue 8, 2024, Pages 975-984]
Chemosensitivity Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
Chitosan Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
Chitosan Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
Chitosan Comparison of different hydroxyapatite composites for bone tissue repair: In vitro and in vivo analyses [Volume 27, Issue 9, 2024, Pages 1155-1161]
Chronic pain Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
Cited2 Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
Clerodane diterpene Synthesized diterpene lactone derivative attenuated Freund’s complete adjuvant-induced arthritis in Wistar rats [Volume 27, Issue 9, 2024, Pages 1197-1208]
CNS Neuroprotective roles of flavonoid “hispidulin” in the central nervous system: A review [Volume 27, Issue 9, 2024, Pages 1077-1084]
Cognitive dysfunction HuangQi Huangqi Gegen decoction ameliorates alcohol-induced cognitive dysfunction via attenuating oxidative stress and enhancing blood-brain barrier integrity in rats through the Keap1-Nrf2/HO-1 signaling pathway [Volume 27, Issue 10, 2024, Pages 1331-1339]
Cognitive impairment High-intensity interval training combined with cannabidiol supplementation improves cognitive impairment by regulating the expression of apolipoprotein E, presenilin-1, and glutamate proteins in a rat model of amyloid β-induced Alzheimer’s disease [Volume 27, Issue 12, 2024, Pages 1583-1591]
Colitis Co-administration of 1,25-dihydroxyvitamin D3 and infliximab improves colitis in mice by modulating Treg differentiation [Volume 27, Issue 9, 2024, Pages 1172-1179]
Collagen I SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
Collagen III SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
Colorectal cancer Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
Combination drug therapy Vitamin C, doxycycline, and azithromycin (VDA) targeted changes in cellular senescence-related genes in human adipose-derived mesenchymal stem cells [Volume 27, Issue 11, 2024, Pages 1380-1388]
Combination therapy Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
Competitive endogenous - RNA Introduction of LPIN1 as a potential diagnostic and prognostic biomarker for gastric cancer via integrative bioinformatics analysis of a competing endogenous RNA network and experimental validation [Volume 27, Issue 11, 2024, Pages 1456-1463]
Computational biology Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
Conditioned medium Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
Conjugated SUMO2/3 MicroRNA miR-188-5p enhances SUMO2/3 conjugation by targeting SENP3 and alleviates focal cerebral ischemia/reperfusion injury in rats [Volume 27, Issue 10, 2024, Pages 1260-1267]
Core/shell nanofiber Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
Corilagin Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
Corticosterone Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring [Volume 27, Issue 9, 2024, Pages 1115-1123]
Costunolide Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
COVID-19 Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
Creatinine Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
Creatinine Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
CREB/BDNF Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
CRISPR/Cas 9 Technique The simultaneous use of CRISPR/Cas9 to knock out the PI3Kca gene with radiation to enhance radiosensitivity and inhibit tumor growth in breast cancer [Volume 27, Issue 12, 2024, Pages 1566-1573]
Crocetin An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
Crocetin Beta-adrenergic receptor stimulation, histamine receptor inhibition, and potassium channel opening contribute to the relaxant effects of crocetin on airway smooth muscle [Volume 27, Issue 10, 2024, Pages 1317-1322]
Crocin Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
Crocin An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
Crocin Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
Crocin Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
Crocin Crocin from saffron ameliorates allergic airway inflammation through NF-κB, IL-17, and Nrf2/HO-1 signaling pathways in mice [Volume 27, Issue 12, 2024, Pages 1624-1631]
Crocus sativus An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
Crocus sativus Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
Curcumin Curcumin and saroglitazar attenuate diet-induced nonalcoholic steatohepatitis by activating the Nrf2 pathway and suppressing ERK1/2 signaling [Volume 27, Issue 8, 2024, Pages 1015-1022]
Cyclooxygenase Beta-adrenergic receptor stimulation, histamine receptor inhibition, and potassium channel opening contribute to the relaxant effects of crocetin on airway smooth muscle [Volume 27, Issue 10, 2024, Pages 1317-1322]
Cyclophosphamide Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
Cyclosporine Renoprotective effect of Limonium duriusculum (de Girard) Kuntze via modulation of oxidative stress/ UPR markers and inflammation during cyclosporine-induced nephrotoxicity in rats [Volume 27, Issue 8, 2024, Pages 1023-1032]
Cytokine Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
Cytokines Protective effect of 1, 8-cineole (eucalyptol) against lead-induced liver injury by ameliorating oxidative stress and inflammation and modulating TLR4/MyD88/NF-κB signaling [Volume 27, Issue 10, 2024, Pages 1293-1299]

D

Degradation Quercetin is a foe in the heart by targeting the hERG potassium channel [Volume 27, Issue 11, 2024, Pages 1397-1404]
Denervation Regenerative role of mast cells and mesenchymal stem cells in histopathology of the sciatic nerve and tibialis cranialis muscle, following denervation in rats [Volume 27, Issue 12, 2024, Pages 1536-1546]
Depression Luteolin reversed anxiety and depressive-like behavior via modulation of the NF-κB/NLRP3 inflammasome axis in the hippocampus of rats subjected to sleep deprivation [Volume 27, Issue 8, 2024, Pages 1050-1058]
Dexmedetomidine Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
Dexpanthenol Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
D-galactose (-)-α-Bisabolol inhibits D-Gal-induced HSF cellular senescence in vitro and prevents skin aging in vivo by reducing SASP [Volume 27, Issue 9, 2024, Pages 1105-1114]
Diabetes Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
Diabetes Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
Diabetes Antiarrhythmic potentials of irisin in ischemia/reperfusion injury of diabetic rats through modulating mitochondria-endoplasmic reticulum interaction and inhibiting pyroptosis [Volume 27, Issue 11, 2024, Pages 1440-1446]
Diabetes Evening primrose oil ameliorates tissue architecture, apoptosis, and oxidative stress in the pancreas of diabetic rats: Possible role of miR-21 [Volume 27, Issue 12, 2024, Pages 1558-1565]
Diabetes Mellitus Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
Diabetes Mellitus Nephroprotective effect of remote ischemic conditioning on type 2 diabetic rats [Volume 27, Issue 10, 2024, Pages 1340-1345]
Diabetes Mellitus Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates diabetes-induced acute lung injury via activating Nrf2/ HO-1 [Volume 27, Issue 11, 2024, Pages 1423-1429]
Diabetes mellitus type 1 Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
Diabetes mellitus-type 2 High-intensity interval training reduces Tau and beta-amyloid accumulation by improving lactate-dependent mitophagy in rats with type 2 diabetes [Volume 27, Issue 11, 2024, Pages 1430-1439]
Diabetic nephropathies Long-term effects of warm water immersion on kidney tissue damage in diabetic rats [Volume 27, Issue 9, 2024, Pages 1162-1171]
Diabetic nephropathy Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
Diabetic nephropathy Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
Diabetic nephropathy Saroglitazar suppresses KIM-1 and type IV collagen in high fat diet and low-dose streptozotocin-induced diabetic nephropathy in Wistar rats [Volume 27, Issue 11, 2024, Pages 1447-1455]
Diabetic peripheral- neuropathy Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
Dietary supplements Recent advancements in the role of phytochemicals and Medicinal plants in prophylaxis and management of Alzheimer’s disease [Volume 27, Issue 11, 2024, Pages 1357-1369]
Diets Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
Diosmin Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
Direct current Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
DNA Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
DNA damage Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
DNA delivery Lactosylated lipid calcium phosphate-based nanoparticles: A promising approach for efficient DNA delivery to hepatocytes [Volume 27, Issue 8, 2024, Pages 952-958]
Doxycycline Vitamin C, doxycycline, and azithromycin (VDA) targeted changes in cellular senescence-related genes in human adipose-derived mesenchymal stem cells [Volume 27, Issue 11, 2024, Pages 1380-1388]
D-Pinitol D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
Drug Delivery An in situ forming gelatin-based hydrogel loaded with soluble amniotic membrane promotes full-thickness wound regeneration in rats [Volume 27, Issue 8, 2024, Pages 1005-1014]
Drug discovery Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
Drug resistance Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
Drug resistance Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
Drug resistance Application of ferroptosis strategy to overcome tumor therapy resistance in breast and different cancer cells [Volume 27, Issue 9, 2024, Pages 1085-1095]
Dyslipidemia Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
Dyslipidemia Thymoquinone: A comprehensive review of its potential role as a monotherapy for metabolic syndrome [Volume 27, Issue 10, 2024, Pages 1214-1227]

E

E6 High-throughput virtual- screening C-71980262, A novel small molecule against human papilloma virus-16 E6 (HPV-16 E6) with anticancer potency against cervical cancer: A computational guided in vitro approach [Volume 27, Issue 11, 2024, Pages 1389-1396]
E-cadherin Fucosyltransferase 3 and 8 promote the metastatic capacity of cancer stem-like cells via CD15s and E-cadherin in esophageal cancer [Volume 27, Issue 8, 2024, Pages 985-995]
Electroacupuncture Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
Electroacupuncture Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
Electrocardiography Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
ELF-EMF Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring [Volume 27, Issue 9, 2024, Pages 1115-1123]
Embelin Medicinal potential of embelin and its nanoformulations: An update on the molecular mechanism and various applications [Volume 27, Issue 10, 2024, Pages 1228-1242]
Embryo development All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
Endoplasmic reticulum - stress Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
Endoplasmic reticulum - stress Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
Endoplasmic reticulum- stress Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
Endoplasmic reticulum-stress Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
Endothelial cells Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
Enzymes Taurine supplementation decreases fat accumulation by suppressing FAS and enhancing ATGL through the ATGL pathway [Volume 27, Issue 12, 2024, Pages 1529-1535]
Epigenomics Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
Epilepsy Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review [Volume 27, Issue 12, 2024, Pages 1492-1505]
Epithelial mesenchymal - transformation Baicalein blocked gastric cancer cell proliferation and invasion through modulated platelet type 12-lipoxygenase [Volume 27, Issue 12, 2024, Pages 1574-1582]
ERK1/2 Curcumin and saroglitazar attenuate diet-induced nonalcoholic steatohepatitis by activating the Nrf2 pathway and suppressing ERK1/2 signaling [Volume 27, Issue 8, 2024, Pages 1015-1022]
ERK1/2 Baicalein blocked gastric cancer cell proliferation and invasion through modulated platelet type 12-lipoxygenase [Volume 27, Issue 12, 2024, Pages 1574-1582]
ER stress Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
ER stress Renoprotective effect of Limonium duriusculum (de Girard) Kuntze via modulation of oxidative stress/ UPR markers and inflammation during cyclosporine-induced nephrotoxicity in rats [Volume 27, Issue 8, 2024, Pages 1023-1032]
Erythropoietin Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
Esophageal cancer stem - cells Fucosyltransferase 3 and 8 promote the metastatic capacity of cancer stem-like cells via CD15s and E-cadherin in esophageal cancer [Volume 27, Issue 8, 2024, Pages 985-995]
Essential oil Comprehensive and updated review on anti-oxidant effects of Nigella sativa and its constituent, thymoquinone, in various disorders [Volume 27, Issue 8, 2024, Pages 923-951]
Eucalyptol Protective effect of 1, 8-cineole (eucalyptol) against lead-induced liver injury by ameliorating oxidative stress and inflammation and modulating TLR4/MyD88/NF-κB signaling [Volume 27, Issue 10, 2024, Pages 1293-1299]
Evening Primrose Oil Evening primrose oil ameliorates tissue architecture, apoptosis, and oxidative stress in the pancreas of diabetic rats: Possible role of miR-21 [Volume 27, Issue 12, 2024, Pages 1558-1565]
Exosome Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
Exosome Doxorubicin-loaded NK exosomes enable cytotoxicity against triple-negative breast cancer spheroids [Volume 27, Issue 12, 2024, Pages 1604-1615]
Exosomes Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
Exosomes Intravenous administration exosomes derived from human amniotic mesenchymal stem cells improves neurological recovery after acute traumatic spinal cord injury in rats [Volume 27, Issue 10, 2024, Pages 1284-1292]

F

FCA model Synthesized diterpene lactone derivative attenuated Freund’s complete adjuvant-induced arthritis in Wistar rats [Volume 27, Issue 9, 2024, Pages 1197-1208]
Febuxostat Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
Fecal microbiota- transplantation Therapeutic effect of fecal microbiota transplantation on rats with liver cirrhosis and its influence on gut microbiota [Volume 27, Issue 9, 2024, Pages 1148-1154]
Fenofibrate Saroglitazar suppresses KIM-1 and type IV collagen in high fat diet and low-dose streptozotocin-induced diabetic nephropathy in Wistar rats [Volume 27, Issue 11, 2024, Pages 1447-1455]
FeONPs-Cur Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
Ferroptosis Application of ferroptosis strategy to overcome tumor therapy resistance in breast and different cancer cells [Volume 27, Issue 9, 2024, Pages 1085-1095]
Fertility agents All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
Fertility rate Effects of lupeol and flutamide on experimentally-induced polycystic ovary syndrome in mice [Volume 27, Issue 8, 2024, Pages 1067-1076]
Fibroblast Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
Fibromyalgia Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
Fibrosis Effects of ivabradine on myocardial autophagia and apoptosis in isoprenaline-induced heart failure in mice [Volume 27, Issue 1, 2024, Pages 107-113]
Fibrosis Effects of lupeol and flutamide on experimentally-induced polycystic ovary syndrome in mice [Volume 27, Issue 8, 2024, Pages 1067-1076]
Flavone Neuroprotective roles of flavonoid “hispidulin” in the central nervous system: A review [Volume 27, Issue 9, 2024, Pages 1077-1084]
Fluorescent light intensity Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
Fluorouracil THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
Food additives Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
Fragility fractures Zinc oxide nanoparticle-reinforced sodium alginate/hydroxyapatite scaffolds for osteoporosis treatment in fragility fracture patients: Development and characterization using artificial neural networks (ANNs) modeling [Volume 27, Issue 12, 2024, Pages 1592-1603]
Fucoidan Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
Fucosyltransferase 3 and 8 Fucosyltransferase 3 and 8 promote the metastatic capacity of cancer stem-like cells via CD15s and E-cadherin in esophageal cancer [Volume 27, Issue 8, 2024, Pages 985-995]

G

Gabapentin Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
GABARAPL1 Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
Garcinia mangostana Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
Gasdermin D Genistein inhibits the release of pro-inflammatory substances from macrophages by suppressing potassium loss- and ROS-mediated caspase-1/gasdermin D pathway activation and pyroptotic cell lysis [Volume 27, Issue 12, 2024, Pages 1506-1514]
Gastric cancer Baicalein blocked gastric cancer cell proliferation and invasion through modulated platelet type 12-lipoxygenase [Volume 27, Issue 12, 2024, Pages 1574-1582]
Gastric ulcer Histopathological and biochemical evaluation of the protective efficacy of Prunus spinosa L. extract in a rat model of indomethacin-induced gastric ulcer [Volume 27, Issue 11, 2024, Pages 1464-1474]
Gelatin Injectable multifunctional hydrogel containing Sphingosine 1-phosphate and human acellular amniotic membrane for skin wound healing [Volume 27, Issue 9, 2024, Pages 1134-1147]
Gelatin polymer scaffold Evaluation of bioactive extract nanoparticles on pulp stem cell behavior relevant to dental care using chemical composition of gelatin-Arabian gum nano polymer [Volume 27, Issue 8, 2024, Pages 975-984]
Gender Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
Gene delivery Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
Gene expression Andrographolide demonstrates anti-proliferative activity in oral cancer by promoting apoptosis, the programmed cell death process [Volume 27, Issue 10, 2024, Pages 1300-1308]
Gene knockout Deletion of protein kinase C θ attenuates hepatic ischemia/reperfusion injury and further elucidates its mechanism in pathophysiology [Volume 27, Issue 10, 2024, Pages 1323-1330]
Genistein Genistein inhibits the release of pro-inflammatory substances from macrophages by suppressing potassium loss- and ROS-mediated caspase-1/gasdermin D pathway activation and pyroptotic cell lysis [Volume 27, Issue 12, 2024, Pages 1506-1514]
Gestational Diabetes Mellitus Effect of mild gestational diabetes mellitus on histological, ultrastructural, and quantitative morphometric alterations of rat fetal liver [Volume 27, Issue 11, 2024, Pages 1405-1409]
Ginkgo biloba L-Arginine-induced acute pancreatitis and its associated lung injury in rats: Down-regulation of TLR-4/MAPK-p38/JNK signaling pathway via Ginkgo biloba extract EGb 761 [Volume 27, Issue 8, 2024, Pages 959-966]
Glioblastoma Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
Glutamate High-intensity interval training combined with cannabidiol supplementation improves cognitive impairment by regulating the expression of apolipoprotein E, presenilin-1, and glutamate proteins in a rat model of amyloid β-induced Alzheimer’s disease [Volume 27, Issue 12, 2024, Pages 1583-1591]
Glutamatergic transmission Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
Glutathione Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
Glutathione Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
Glutathione peroxidase Application of ferroptosis strategy to overcome tumor therapy resistance in breast and different cancer cells [Volume 27, Issue 9, 2024, Pages 1085-1095]
Glycerol Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
Glycogen synthase kinase 3 beta Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
Gold colloid Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
Growth differentiation-factor 15 Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
Growth Factor All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
Growth Factor An in situ forming gelatin-based hydrogel loaded with soluble amniotic membrane promotes full-thickness wound regeneration in rats [Volume 27, Issue 8, 2024, Pages 1005-1014]
Gut microbiota Therapeutic effect of fecal microbiota transplantation on rats with liver cirrhosis and its influence on gut microbiota [Volume 27, Issue 9, 2024, Pages 1148-1154]

H

Haemophilia therapy Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
Handle region peptide Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
Harmaline-ag containing- folate-linked chitosan-nanoparticles (HA-fCNP) In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system [Volume 27, Issue 2, 2024, Pages 180-187]
Heart protection Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
Heart rate Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
Heat-shock proteins (HSP70) Long-term effects of warm water immersion on kidney tissue damage in diabetic rats [Volume 27, Issue 9, 2024, Pages 1162-1171]
Heme oxygenase-1 Crocin from saffron ameliorates allergic airway inflammation through NF-κB, IL-17, and Nrf2/HO-1 signaling pathways in mice [Volume 27, Issue 12, 2024, Pages 1624-1631]
Hemophilia A Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
Hepatic fibrosis Resveratrol treatment ameliorates hepatic damage via the TGF-β/SMAD signaling pathway in a phenobarbital/CCl4-induced hepatic fibrosis model [Volume 27, Issue 9, 2024, Pages 1124-1133]
Hepatic ischemia/reperfusion injury Deletion of protein kinase C θ attenuates hepatic ischemia/reperfusion injury and further elucidates its mechanism in pathophysiology [Volume 27, Issue 10, 2024, Pages 1323-1330]
Hepatocellular carcinoma Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
Hepatocytes Lactosylated lipid calcium phosphate-based nanoparticles: A promising approach for efficient DNA delivery to hepatocytes [Volume 27, Issue 8, 2024, Pages 952-958]
Hepatoprotection Inflammation Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inﬂammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
Hepatotoxicity Naringin alleviates gefitinib-induced hepatotoxicity through anti-oxidation, inhibition of apoptosis, and autophagy [Volume 27, Issue 10, 2024, Pages 1309-1316]
HepG2 Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
Herbal Medicine Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review [Volume 27, Issue 12, 2024, Pages 1492-1505]
High cholesterol diet Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
High-fat diet Taurine supplementation decreases fat accumulation by suppressing FAS and enhancing ATGL through the ATGL pathway [Volume 27, Issue 12, 2024, Pages 1529-1535]
High-intensity interval - training High-intensity interval training reduces Tau and beta-amyloid accumulation by improving lactate-dependent mitophagy in rats with type 2 diabetes [Volume 27, Issue 11, 2024, Pages 1430-1439]
High-intensity interval - training High-intensity interval training combined with cannabidiol supplementation improves cognitive impairment by regulating the expression of apolipoprotein E, presenilin-1, and glutamate proteins in a rat model of amyloid β-induced Alzheimer’s disease [Volume 27, Issue 12, 2024, Pages 1583-1591]
Hippocampus Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
Hippocampus Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
Hippocampus Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
Hippocampus Luteolin reversed anxiety and depressive-like behavior via modulation of the NF-κB/NLRP3 inflammasome axis in the hippocampus of rats subjected to sleep deprivation [Volume 27, Issue 8, 2024, Pages 1050-1058]
Hippocampus High-intensity interval training reduces Tau and beta-amyloid accumulation by improving lactate-dependent mitophagy in rats with type 2 diabetes [Volume 27, Issue 11, 2024, Pages 1430-1439]
Histamine receptors Beta-adrenergic receptor stimulation, histamine receptor inhibition, and potassium channel opening contribute to the relaxant effects of crocetin on airway smooth muscle [Volume 27, Issue 10, 2024, Pages 1317-1322]
Histology Effect of mild gestational diabetes mellitus on histological, ultrastructural, and quantitative morphometric alterations of rat fetal liver [Volume 27, Issue 11, 2024, Pages 1405-1409]
Histology Regenerative role of mast cells and mesenchymal stem cells in histopathology of the sciatic nerve and tibialis cranialis muscle, following denervation in rats [Volume 27, Issue 12, 2024, Pages 1536-1546]
Histone deacetylase- inhibitors Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
Histopathology Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
HMGB1 Genistein inhibits the release of pro-inflammatory substances from macrophages by suppressing potassium loss- and ROS-mediated caspase-1/gasdermin D pathway activation and pyroptotic cell lysis [Volume 27, Issue 12, 2024, Pages 1506-1514]
HMGB1/NF-κB signaling - pathway Autophagy inhibitor 3-methyladenine attenuates renal injury in streptozotocin-induced diabetic mice [Volume 27, Issue 7, 2024, Pages 793-800]
HO-1 Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates diabetes-induced acute lung injury via activating Nrf2/ HO-1 [Volume 27, Issue 11, 2024, Pages 1423-1429]
HOMA-IR Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
HPV C-71980262, A novel small molecule against human papilloma virus-16 E6 (HPV-16 E6) with anticancer potency against cervical cancer: A computational guided in vitro approach [Volume 27, Issue 11, 2024, Pages 1389-1396]
HspX/EsxS Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
HSV-1 Inactivated herpes simplex virus-1 vaccine formulated in aqueous and alcoholic extracts of propolis boosts cellular and IgG responses [Volume 27, Issue 9, 2024, Pages 1209-1213]
HTR-8/SVneo cells Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
Human THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
HUVEC Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
Hydrogel dressing An in situ forming gelatin-based hydrogel loaded with soluble amniotic membrane promotes full-thickness wound regeneration in rats [Volume 27, Issue 8, 2024, Pages 1005-1014]
Hydrogels Injectable multifunctional hydrogel containing Sphingosine 1-phosphate and human acellular amniotic membrane for skin wound healing [Volume 27, Issue 9, 2024, Pages 1134-1147]
Hydrotherapy Long-term effects of warm water immersion on kidney tissue damage in diabetic rats [Volume 27, Issue 9, 2024, Pages 1162-1171]
Hydroxyapatite Comparison of different hydroxyapatite composites for bone tissue repair: In vitro and in vivo analyses [Volume 27, Issue 9, 2024, Pages 1155-1161]
Hydroxycitric acid Metabolomics analysis reveals a protective effect of hydroxycitric acid on calcium oxalate-induced kidney injury [Volume 27, Issue 10, 2024, Pages 1243-1250]
Hyperglycemia Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
Hyperglycemia Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
Hyperglycemia The protective effects of alpha-pinene on high glucose-induced oxidative stress and inflammation in HepG2 cells [Volume 27, Issue 8, 2024, Pages 967-974]
Hyperlipidemia Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
Hypertension Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
Hypertension Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
Hypothalamic-pituitary-adrenal system Prolonged stress alters the PC1/PC2 ratio in the rat lateral hypothalamus, implicating impaired orexin maturation [Volume 27, Issue 8, 2024, Pages 1059-1066]
Hypoxia-induced pulmonary hypertension Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
Hypoxia inducible factor Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
Hypoxia-inducible factor-1 Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]

I

Immflamation Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
Immune Infiltrates Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
Immune responses Candidiasis in breast cancer: Tumor progression or not? [Volume 27, Issue 11, 2024, Pages 1346-1356]
Immune system Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
Immunotherapy Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
Implant Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
Inflammation Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
Inflammation Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
Inflammation Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
Inflammation TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
Inflammation D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
Inflammation Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
Inflammation Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
Inflammation Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
Inflammation Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
Inflammation Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
Inflammation Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
Inflammation Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
Inflammation Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
Inflammation Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
Inflammation Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
Inflammation Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
Inflammation Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
Inflammation Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
Inflammation L-Arginine-induced acute pancreatitis and its associated lung injury in rats: Down-regulation of TLR-4/MAPK-p38/JNK signaling pathway via Ginkgo biloba extract EGb 761 [Volume 27, Issue 8, 2024, Pages 959-966]
Inflammation The protective effects of alpha-pinene on high glucose-induced oxidative stress and inflammation in HepG2 cells [Volume 27, Issue 8, 2024, Pages 967-974]
Inflammation Effects of Olea oleaster leaf extract and purified oleuropein on ethanol-induced gastric ulcer in male Wistar rats [Volume 27, Issue 8, 2024, Pages 996-1004]
Inflammation Neuroprotective roles of flavonoid “hispidulin” in the central nervous system: A review [Volume 27, Issue 9, 2024, Pages 1077-1084]
Inflammation Nephroprotective effect of remote ischemic conditioning on type 2 diabetic rats [Volume 27, Issue 10, 2024, Pages 1340-1345]
Inflammation Effect of thymoquinone on NRF2 / NF-kB / MAPK pathway in methotrexate-induced rat testis injury [Volume 27, Issue 11, 2024, Pages 1410-1416]
Inflammation Antiarrhythmic potentials of irisin in ischemia/reperfusion injury of diabetic rats through modulating mitochondria-endoplasmic reticulum interaction and inhibiting pyroptosis [Volume 27, Issue 11, 2024, Pages 1440-1446]
Inflammatory bowel disease Curcumin chitosan microspheres regulate Th17/Treg balance via IGF2BP1- mediated m6A modification of LRP5 in ulcerative colitis [Volume 27, Issue 10, 2024, Pages 1276-1283]
Inflammatory markers Renoprotective effect of Limonium duriusculum (de Girard) Kuntze via modulation of oxidative stress/ UPR markers and inflammation during cyclosporine-induced nephrotoxicity in rats [Volume 27, Issue 8, 2024, Pages 1023-1032]
Infliximab Co-administration of 1,25-dihydroxyvitamin D3 and infliximab improves colitis in mice by modulating Treg differentiation [Volume 27, Issue 9, 2024, Pages 1172-1179]
Inhibition Genistein inhibits the release of pro-inflammatory substances from macrophages by suppressing potassium loss- and ROS-mediated caspase-1/gasdermin D pathway activation and pyroptotic cell lysis [Volume 27, Issue 12, 2024, Pages 1506-1514]
Injury Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
In-silico analysis Andrographolide demonstrates anti-proliferative activity in oral cancer by promoting apoptosis, the programmed cell death process [Volume 27, Issue 10, 2024, Pages 1300-1308]
Insulin Long-term effects of warm water immersion on kidney tissue damage in diabetic rats [Volume 27, Issue 9, 2024, Pages 1162-1171]
Integrin Effects of dose-dependent chronic caffeine consumption in a rat burn wound model: Histopathological and immunohistochemical evaluation [Volume 27, Issue 9, 2024, Pages 1180-1186]
Interferon gamma Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
Interleukin-10 Co-administration of 1,25-dihydroxyvitamin D3 and infliximab improves colitis in mice by modulating Treg differentiation [Volume 27, Issue 9, 2024, Pages 1172-1179]
Intervention strategy Zinc oxide nanoparticle-reinforced sodium alginate/hydroxyapatite scaffolds for osteoporosis treatment in fragility fracture patients: Development and characterization using artificial neural networks (ANNs) modeling [Volume 27, Issue 12, 2024, Pages 1592-1603]
Intervertebral disc-degeneration Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
Intestinal flora Therapeutic effect of fecal microbiota transplantation on rats with liver cirrhosis and its influence on gut microbiota [Volume 27, Issue 9, 2024, Pages 1148-1154]
Intracerebral hemorrhage NLRP3 inflammasome Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
Intraperitoneal injection Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
In vitro oocyte maturation - techniques All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
Iridaceae Moraea sisyrinchium inhibits proliferation, cell cycle, and migration of cancerous cells, and decreases angiogenesis in chick chorioallantoic membrane [Volume 27, Issue 1, 2024, Pages 57-65]
Iron metabolism Application of ferroptosis strategy to overcome tumor therapy resistance in breast and different cancer cells [Volume 27, Issue 9, 2024, Pages 1085-1095]
Ischemia TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
Ischemia-reperfusion Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
Ischemia/Reperfusion injury MicroRNA miR-188-5p enhances SUMO2/3 conjugation by targeting SENP3 and alleviates focal cerebral ischemia/reperfusion injury in rats [Volume 27, Issue 10, 2024, Pages 1260-1267]
Ischemic conditioning Nephroprotective effect of remote ischemic conditioning on type 2 diabetic rats [Volume 27, Issue 10, 2024, Pages 1340-1345]
Ischemic stroke MicroRNA miR-188-5p enhances SUMO2/3 conjugation by targeting SENP3 and alleviates focal cerebral ischemia/reperfusion injury in rats [Volume 27, Issue 10, 2024, Pages 1260-1267]
ISCOMATRIX Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
Isoproterenol D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
Isorhamnetin Isorhamnetin alleviates symptoms and inhibits oxidative stress levels in rats with pulmonary arterial hypertension [Volume 27, Issue 12, 2024, Pages 1616-1623]

L

Lactates High-intensity interval training reduces Tau and beta-amyloid accumulation by improving lactate-dependent mitophagy in rats with type 2 diabetes [Volume 27, Issue 11, 2024, Pages 1430-1439]
Lactobacillus Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
Laminin Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
Langendorff heart Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
L-arginine L-Arginine-induced acute pancreatitis and its associated lung injury in rats: Down-regulation of TLR-4/MAPK-p38/JNK signaling pathway via Ginkgo biloba extract EGb 761 [Volume 27, Issue 8, 2024, Pages 959-966]
LC3 Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
LC-HRMS Histopathological and biochemical evaluation of the protective efficacy of Prunus spinosa L. extract in a rat model of indomethacin-induced gastric ulcer [Volume 27, Issue 11, 2024, Pages 1464-1474]
LC-MS/MS Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inﬂammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
Lead acetate Protective effect of 1, 8-cineole (eucalyptol) against lead-induced liver injury by ameliorating oxidative stress and inflammation and modulating TLR4/MyD88/NF-κB signaling [Volume 27, Issue 10, 2024, Pages 1293-1299]
Limonium duriusculum Renoprotective effect of Limonium duriusculum (de Girard) Kuntze via modulation of oxidative stress/ UPR markers and inflammation during cyclosporine-induced nephrotoxicity in rats [Volume 27, Issue 8, 2024, Pages 1023-1032]
Lipid metabolism Application of ferroptosis strategy to overcome tumor therapy resistance in breast and different cancer cells [Volume 27, Issue 9, 2024, Pages 1085-1095]
Lipid metabolism Taurine supplementation decreases fat accumulation by suppressing FAS and enhancing ATGL through the ATGL pathway [Volume 27, Issue 12, 2024, Pages 1529-1535]
Lipofuscin Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
Lipopolysaccharide Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
Liposome How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
Liver Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
Liver Resveratrol treatment ameliorates hepatic damage via the TGF-β/SMAD signaling pathway in a phenobarbital/CCl4-induced hepatic fibrosis model [Volume 27, Issue 9, 2024, Pages 1124-1133]
Liver Protective effect of 1, 8-cineole (eucalyptol) against lead-induced liver injury by ameliorating oxidative stress and inflammation and modulating TLR4/MyD88/NF-κB signaling [Volume 27, Issue 10, 2024, Pages 1293-1299]
Liver Effect of mild gestational diabetes mellitus on histological, ultrastructural, and quantitative morphometric alterations of rat fetal liver [Volume 27, Issue 11, 2024, Pages 1405-1409]
Liver Cirrhosis Therapeutic effect of fecal microbiota transplantation on rats with liver cirrhosis and its influence on gut microbiota [Volume 27, Issue 9, 2024, Pages 1148-1154]
Liver injury Unacylated ghrelin attenuates acute liver injury and hyperlipidemia via its anti-inflammatory and anti-oxidative activities [Volume 27, Issue 1, 2024, Pages 49-56]
Liver injury Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
Long QT syndrome Quercetin is a foe in the heart by targeting the hERG potassium channel [Volume 27, Issue 11, 2024, Pages 1397-1404]
Long-term potentiation Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
Loratadine Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
Low-density lipoprotein Preclinical models of atherosclerosis: An overview [Volume 27, Issue 5, 2024, Pages 535-542]
Lung Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
Lung cancer Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
Lung injury L-Arginine-induced acute pancreatitis and its associated lung injury in rats: Down-regulation of TLR-4/MAPK-p38/JNK signaling pathway via Ginkgo biloba extract EGb 761 [Volume 27, Issue 8, 2024, Pages 959-966]
Lung Neoplasms Apatinib has anti-tumor effects and induces autophagy in lung cancer cells with high expression of VEGFR-2 [Volume 27, Issue 11, 2024, Pages 1370-1379]
Luteolin A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]
Luteolin Luteolin reversed anxiety and depressive-like behavior via modulation of the NF-κB/NLRP3 inflammasome axis in the hippocampus of rats subjected to sleep deprivation [Volume 27, Issue 8, 2024, Pages 1050-1058]

M

Machine-processed Isorhamnetin alleviates symptoms and inhibits oxidative stress levels in rats with pulmonary arterial hypertension [Volume 27, Issue 12, 2024, Pages 1616-1623]
Macrophage inflammatory proteins Revitalizing polycystic ovary syndrome: The therapeutic impact of low-dose ∆9 tetrahydrocannabinol through reduction of oxidative stress and modulation of macrophage polarization [Volume 27, Issue 8, 2024, Pages 1040-1049]
Malondialdehyde Renoprotective effects of crocin against colistin-induced nephrotoxicity in a rat model [Volume 27, Issue 2, 2024, Pages 151-156]
Malondialdehyde Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
MAP kinase signaling - system Electroacupuncture at the Dazhui and Baihui acupoints and different frequencies (10 and 50 Hz) protects against apoptosis by up-regulating ERK1/2-mediated signaling in rats after global cerebral ischemia [Volume 27, Issue 6, 2024, Pages 706-716]
MAPK pathway Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
Mast cells Regenerative role of mast cells and mesenchymal stem cells in histopathology of the sciatic nerve and tibialis cranialis muscle, following denervation in rats [Volume 27, Issue 12, 2024, Pages 1536-1546]
MDA-MB-231 cell line The simultaneous use of CRISPR/Cas9 to knock out the PI3Kca gene with radiation to enhance radiosensitivity and inhibit tumor growth in breast cancer [Volume 27, Issue 12, 2024, Pages 1566-1573]
Medical interventionst Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
Medicinal Plants Recent advancements in the role of phytochemicals and Medicinal plants in prophylaxis and management of Alzheimer’s disease [Volume 27, Issue 11, 2024, Pages 1357-1369]
Melanin Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
Melatonin Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
Melatonin Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
Memory Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
Memory Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
Memory Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes [Volume 27, Issue 10, 2024, Pages 1268-1275]
Mesenchymal stem cells Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
Mesenchymal stem cells Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury [Volume 27, Issue 3, 2024, Pages 375-382]
Mesenchymal stem cells Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
Mesenchymal stem cells Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
Mesenchymal stem cells Intravenous administration exosomes derived from human amniotic mesenchymal stem cells improves neurological recovery after acute traumatic spinal cord injury in rats [Volume 27, Issue 10, 2024, Pages 1284-1292]
Mesenchymal stem cells Stimulating effect of nanocurcumin and crocin on proliferation and pluripotency of bone marrow-derived mesenchymal stem cells [Volume 27, Issue 9, 2024, Pages 1187-1196]
Mesenchymal stem cells Regenerative role of mast cells and mesenchymal stem cells in histopathology of the sciatic nerve and tibialis cranialis muscle, following denervation in rats [Volume 27, Issue 12, 2024, Pages 1536-1546]
Messenger RNA Introduction of LPIN1 as a potential diagnostic and prognostic biomarker for gastric cancer via integrative bioinformatics analysis of a competing endogenous RNA network and experimental validation [Volume 27, Issue 11, 2024, Pages 1456-1463]
Metabolomics Metabolomics analysis reveals a protective effect of hydroxycitric acid on calcium oxalate-induced kidney injury [Volume 27, Issue 10, 2024, Pages 1243-1250]
Metal-organic frameworks Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
Metformin Metformin improves memory via AMPK/mTOR-dependent route in a rat model of Alzheimer’s disease [Volume 27, Issue 3, 2024, Pages 360-365]
Metformin Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
Methotrexate Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
Methotrexate Effect of thymoquinone on NRF2 / NF-kB / MAPK pathway in methotrexate-induced rat testis injury [Volume 27, Issue 11, 2024, Pages 1410-1416]
Methylene blue Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
Methylthioninium chloride Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
Microbial Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
Microbiology Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
MicroRNA Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
Migration Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
Migration Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
Migration Evaluation of bioactive extract nanoparticles on pulp stem cell behavior relevant to dental care using chemical composition of gelatin-Arabian gum nano polymer [Volume 27, Issue 8, 2024, Pages 975-984]
MiR-188-5p SENP3 MicroRNA miR-188-5p enhances SUMO2/3 conjugation by targeting SENP3 and alleviates focal cerebral ischemia/reperfusion injury in rats [Volume 27, Issue 10, 2024, Pages 1260-1267]
MiRNA-412-5p Effect of miR-412-5p–loaded exosomes in H9c2 cardiomyocytes via the MAPK pathway [Volume 27, Issue 6, 2024, Pages 755-760]
Mitochondria Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
Mitochondria Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice [Volume 27, Issue 12, 2024, Pages 1515-1528]
Mitochondria High-intensity interval training reduces Tau and beta-amyloid accumulation by improving lactate-dependent mitophagy in rats with type 2 diabetes [Volume 27, Issue 11, 2024, Pages 1430-1439]
Mitochondrial dysfunction N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
Mitochondrial membrane- potential Andrographolide demonstrates anti-proliferative activity in oral cancer by promoting apoptosis, the programmed cell death process [Volume 27, Issue 10, 2024, Pages 1300-1308]
Mitogen-activated protein - kinase 3 Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer [Volume 27, Issue 7, 2024, Pages 813-824]
Mitophagy High-intensity interval training reduces Tau and beta-amyloid accumulation by improving lactate-dependent mitophagy in rats with type 2 diabetes [Volume 27, Issue 11, 2024, Pages 1430-1439]
MMP-9 Effects of dose-dependent chronic caffeine consumption in a rat burn wound model: Histopathological and immunohistochemical evaluation [Volume 27, Issue 9, 2024, Pages 1180-1186]
Molecular dynamic-simulations C-71980262, A novel small molecule against human papilloma virus-16 E6 (HPV-16 E6) with anticancer potency against cervical cancer: A computational guided in vitro approach [Volume 27, Issue 11, 2024, Pages 1389-1396]
Molecular mechanism Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
Molecular signaling Testosterone signaling pathways for reducing neuropathic pain in a rat model of spinothalamic tract lesion [Volume 27, Issue 11, 2024, Pages 1417-1422]
Molecular targeted therapy Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
Monoamines Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
Monocrotaline Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
Monocrotaline Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
Morphometry Effect of mild gestational diabetes mellitus on histological, ultrastructural, and quantitative morphometric alterations of rat fetal liver [Volume 27, Issue 11, 2024, Pages 1405-1409]
Motor Activity Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
Mouse Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
Mouse Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
MPLA Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
Muscle Regenerative role of mast cells and mesenchymal stem cells in histopathology of the sciatic nerve and tibialis cranialis muscle, following denervation in rats [Volume 27, Issue 12, 2024, Pages 1536-1546]
Mycobacterium tuberculosis Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
Mycobacterium tuberculosis Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
Myelin protein zero Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
Myocardial ischemia - reperfusion A newly synthesized flavone avoids COMT-catalyzed methylation and mitigates myocardial ischemia/reperfusion injury in H9C2 cells via JNK and P38 pathways [Volume 27, Issue 4, 2024, Pages 492-499]
Myocardial ischemia/reperfusion injury Melatonin enhanced the cardioprotective effects of HTK solution on Langendorff-perfused mouse hearts subjected to ischemia/reperfusion [Volume 27, Issue 3, 2024, Pages 366-374]
Myoglobin Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
Myoglobin Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]

N

N6-methyladenosine- modification Curcumin chitosan microspheres regulate Th17/Treg balance via IGF2BP1- mediated m6A modification of LRP5 in ulcerative colitis [Volume 27, Issue 10, 2024, Pages 1276-1283]
N-acetyl cysteine Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
N-acetylcysteine Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
N-acetylcysteine N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
NADH oxidase Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
NADPH oxidase Chronic stress-induced anxiety-like behavior, hippocampal oxidative, and endoplasmic reticulum stress are reversed by young plasma transfusion in aged adult rats [Volume 27, Issue 1, 2024, Pages 114-121]
NAFLD Curcumin and saroglitazar attenuate diet-induced nonalcoholic steatohepatitis by activating the Nrf2 pathway and suppressing ERK1/2 signaling [Volume 27, Issue 8, 2024, Pages 1015-1022]
NAFLD/NASH Suppression of TGF-β/Smad3 signaling pathway by Capparis spinosa and quercetin in a rat model of nonalcoholic steatohepatitis [Volume 27, Issue 9, 2024, Pages 1096-1104]
Nalm-6 Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
Nanoemulsion How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
Nanofibrous scaffold Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
Nanoparticle Crocin nano-chitosan-coated compound improves anxiety disorders, learning, and spatial memory in Alzheimer’s model induced by beta-amyloid in rats [Volume 27, Issue 7, 2024, Pages 879-887]
Nanoparticle Lactosylated lipid calcium phosphate-based nanoparticles: A promising approach for efficient DNA delivery to hepatocytes [Volume 27, Issue 8, 2024, Pages 952-958]
Nanoparticles Medicinal potential of embelin and its nanoformulations: An update on the molecular mechanism and various applications [Volume 27, Issue 10, 2024, Pages 1228-1242]
Nanostructures Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
Nanotechnology Stimulating effect of nanocurcumin and crocin on proliferation and pluripotency of bone marrow-derived mesenchymal stem cells [Volume 27, Issue 9, 2024, Pages 1187-1196]
Naringin Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
Naringin Naringin alleviates gefitinib-induced hepatotoxicity through anti-oxidation, inhibition of apoptosis, and autophagy [Volume 27, Issue 10, 2024, Pages 1309-1316]
Nasal administration Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
Nasal delivery Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
Nasopharyngeal carcinoma Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma [Volume 27, Issue 2, 2024, Pages 157-164]
Natural killer cells Doxorubicin-loaded NK exosomes enable cytotoxicity against triple-negative breast cancer spheroids [Volume 27, Issue 12, 2024, Pages 1604-1615]
Natural products Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
Necroptosis Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inﬂammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
Necrosis Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
Necrostatin-1 Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inﬂammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
Nedd4 Quercetin is a foe in the heart by targeting the hERG potassium channel [Volume 27, Issue 11, 2024, Pages 1397-1404]
Neoplasms Application of ferroptosis strategy to overcome tumor therapy resistance in breast and different cancer cells [Volume 27, Issue 9, 2024, Pages 1085-1095]
Nephrotoxicity Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
Nephrotoxicity 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
Nephrotoxicity Renoprotective effect of Limonium duriusculum (de Girard) Kuntze via modulation of oxidative stress/ UPR markers and inflammation during cyclosporine-induced nephrotoxicity in rats [Volume 27, Issue 8, 2024, Pages 1023-1032]
Nerve growth factor Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
Neural regeneration Intravenous administration exosomes derived from human amniotic mesenchymal stem cells improves neurological recovery after acute traumatic spinal cord injury in rats [Volume 27, Issue 10, 2024, Pages 1284-1292]
Neurodegenerative diseases Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review [Volume 27, Issue 12, 2024, Pages 1492-1505]
Neurodegenerative- disorders Recent advancements in the role of phytochemicals and Medicinal plants in prophylaxis and management of Alzheimer’s disease [Volume 27, Issue 11, 2024, Pages 1357-1369]
Neurogenesis Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
Neuroinflammation Luteolin reversed anxiety and depressive-like behavior via modulation of the NF-κB/NLRP3 inflammasome axis in the hippocampus of rats subjected to sleep deprivation [Volume 27, Issue 8, 2024, Pages 1050-1058]
Neuropathic pain Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
Neuropathic pain Testosterone signaling pathways for reducing neuropathic pain in a rat model of spinothalamic tract lesion [Volume 27, Issue 11, 2024, Pages 1417-1422]
Neuropeptide Q Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
Neuroprotection Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
Neuroprotection D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
Neuroprotective Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
Neurosurgery Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
Neurotoxicity D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
Neurotoxicity Syndromes Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
NF-κB Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
NF-κB Ameliorative effects of the melatonin on some cytokine levels, NF-κB immunoreactivity, and apoptosis in rats with cerulein-induced acute pancreatitis [Volume 27, Issue 3, 2024, Pages 279-285]
Nigella Sativa Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [Volume 27, Issue 5, 2024, Pages 552-559]
Nigella Sativa Comprehensive and updated review on anti-oxidant effects of Nigella sativa and its constituent, thymoquinone, in various disorders [Volume 27, Issue 8, 2024, Pages 923-951]
Nigella Sativa Thymoquinone: A comprehensive review of its potential role as a monotherapy for metabolic syndrome [Volume 27, Issue 10, 2024, Pages 1214-1227]
Nitric oxide Effects of Olea oleaster leaf extract and purified oleuropein on ethanol-induced gastric ulcer in male Wistar rats [Volume 27, Issue 8, 2024, Pages 996-1004]
NOD mice Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
Non-alcoholic fatty liver disease Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
Non-alcoholic steatohepatitis Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
NOTCH Effects of crocin on the enhancement of in vitro neurogenesis: Involvement of Notch and CREB/BDNF signaling pathways [Volume 27, Issue 7, 2024, Pages 914-922]
Nrf2 Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]
Nrf2 Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
Nrf2 Curcumin and saroglitazar attenuate diet-induced nonalcoholic steatohepatitis by activating the Nrf2 pathway and suppressing ERK1/2 signaling [Volume 27, Issue 8, 2024, Pages 1015-1022]
Nrf2 Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates diabetes-induced acute lung injury via activating Nrf2/ HO-1 [Volume 27, Issue 11, 2024, Pages 1423-1429]
Nrf2/HO-1 pathway Pathophysiology Deletion of protein kinase C θ attenuates hepatic ischemia/reperfusion injury and further elucidates its mechanism in pathophysiology [Volume 27, Issue 10, 2024, Pages 1323-1330]
Nuclear erythroid 2-related - factor 2 Crocin from saffron ameliorates allergic airway inflammation through NF-κB, IL-17, and Nrf2/HO-1 signaling pathways in mice [Volume 27, Issue 12, 2024, Pages 1624-1631]
Nuclear factor Kappa B Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]

O

Obesity Role of apigenin in targeting metabolic syndrome: A systematic review [Volume 27, Issue 5, 2024, Pages 524-534]
Obesity Thymoquinone: A comprehensive review of its potential role as a monotherapy for metabolic syndrome [Volume 27, Issue 10, 2024, Pages 1214-1227]
Octreotide Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
Olea oleaster Effects of Olea oleaster leaf extract and purified oleuropein on ethanol-induced gastric ulcer in male Wistar rats [Volume 27, Issue 8, 2024, Pages 996-1004]
Oleuropein Effects of Olea oleaster leaf extract and purified oleuropein on ethanol-induced gastric ulcer in male Wistar rats [Volume 27, Issue 8, 2024, Pages 996-1004]
Orexin receptors Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
Orexins Prolonged stress alters the PC1/PC2 ratio in the rat lateral hypothalamus, implicating impaired orexin maturation [Volume 27, Issue 8, 2024, Pages 1059-1066]
Organ culture Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system [Volume 27, Issue 10, 2024, Pages 1251-1259]
Osteoarthritis Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
Osteoblast Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
Osteogenesis Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
Osteoinduction Comparison of different hydroxyapatite composites for bone tissue repair: In vitro and in vivo analyses [Volume 27, Issue 9, 2024, Pages 1155-1161]
Osteomyelitis Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
Osteoporosis Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
Osteoporosis Zinc oxide nanoparticle-reinforced sodium alginate/hydroxyapatite scaffolds for osteoporosis treatment in fragility fracture patients: Development and characterization using artificial neural networks (ANNs) modeling [Volume 27, Issue 12, 2024, Pages 1592-1603]
Ovalbumin Crocin from saffron ameliorates allergic airway inflammation through NF-κB, IL-17, and Nrf2/HO-1 signaling pathways in mice [Volume 27, Issue 12, 2024, Pages 1624-1631]
Oxaliplatin Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
Oxidative stress Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
Oxidative stress Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
Oxidative stress Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
Oxidative stress D-Pinitol improves cognitive dysfunction and neuronal damage induced by isoproterenol via modulation of NF-κB/BDNF/GFAP signaling in Swiss albino mice [Volume 27, Issue 3, 2024, Pages 326-334]
Oxidative stress Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
Oxidative stress Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
Oxidative stress Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
Oxidative stress 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
Oxidative stress Genista cephalantha Spach. protects against acetaminophen-induced liver failure via preserving the glutathione redox system, reducing inﬂammatory response, and inhibiting hepatocyte death in rats [Volume 27, Issue 5, 2024, Pages 630-639]
Oxidative stress Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
Oxidative stress Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
Oxidative stress Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
Oxidative stress Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
Oxidative stress The protective effects of alpha-pinene on high glucose-induced oxidative stress and inflammation in HepG2 cells [Volume 27, Issue 8, 2024, Pages 967-974]
Oxidative stress Comprehensive and updated review on anti-oxidant effects of Nigella sativa and its constituent, thymoquinone, in various disorders [Volume 27, Issue 8, 2024, Pages 923-951]
Oxidative stress Renoprotective effect of Limonium duriusculum (de Girard) Kuntze via modulation of oxidative stress/ UPR markers and inflammation during cyclosporine-induced nephrotoxicity in rats [Volume 27, Issue 8, 2024, Pages 1023-1032]
Oxidative stress Neuroprotective roles of flavonoid “hispidulin” in the central nervous system: A review [Volume 27, Issue 9, 2024, Pages 1077-1084]
Oxidative stress Huangqi Gegen decoction ameliorates alcohol-induced cognitive dysfunction via attenuating oxidative stress and enhancing blood-brain barrier integrity in rats through the Keap1-Nrf2/HO-1 signaling pathway [Volume 27, Issue 10, 2024, Pages 1331-1339]
Oxidative stress Long-term effects of warm water immersion on kidney tissue damage in diabetic rats [Volume 27, Issue 9, 2024, Pages 1162-1171]
Oxidative stress Protective effect of 1, 8-cineole (eucalyptol) against lead-induced liver injury by ameliorating oxidative stress and inflammation and modulating TLR4/MyD88/NF-κB signaling [Volume 27, Issue 10, 2024, Pages 1293-1299]
Oxidative stress Nephroprotective effect of remote ischemic conditioning on type 2 diabetic rats [Volume 27, Issue 10, 2024, Pages 1340-1345]
Oxidative stress Effect of thymoquinone on NRF2 / NF-kB / MAPK pathway in methotrexate-induced rat testis injury [Volume 27, Issue 11, 2024, Pages 1410-1416]
Oxidative stress Catalpol alleviates amyloid- generation and neuronal oxidative stress injury via activating the Keap1-Nrf2/ARE signaling pathway in the immortalized lymphocytes from patients with late-onset Alzheimer’s disease and SKNMC cells co-culture model [Volume 27, Issue 12, 2024, Pages 1547-1557]
Oxidative stress Isorhamnetin alleviates symptoms and inhibits oxidative stress levels in rats with pulmonary arterial hypertension [Volume 27, Issue 12, 2024, Pages 1616-1623]
Oxidative stresses Revitalizing polycystic ovary syndrome: The therapeutic impact of low-dose ∆9 tetrahydrocannabinol through reduction of oxidative stress and modulation of macrophage polarization [Volume 27, Issue 8, 2024, Pages 1040-1049]

P

P53 C-71980262, A novel small molecule against human papilloma virus-16 E6 (HPV-16 E6) with anticancer potency against cervical cancer: A computational guided in vitro approach [Volume 27, Issue 11, 2024, Pages 1389-1396]
Pancreas Evening primrose oil ameliorates tissue architecture, apoptosis, and oxidative stress in the pancreas of diabetic rats: Possible role of miR-21 [Volume 27, Issue 12, 2024, Pages 1558-1565]
Pantoprazole Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
Paraquat Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
Paraquat Evaluation of the influence of N-Acetylcysteine and broccoli extract on systemic paraquat poisoning: Implications for biochemical, physiological, and histopathological parameters in rats [Volume 27, Issue 7, 2024, Pages 895-903]
Parathyroid hormone Proton-pump inhibitor-induced bone loss is preventable by concomitant use of a long-acting somatostatin analogue [Volume 27, Issue 2, 2024, Pages 165-169]
Paraventricular hypothalamic nucleus Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
Parkinson’s disease Assessment of the neuroprotective effect of green synthesized iron oxide nanoparticles capped with curcumin against a rat model of Parkinson’s disease [Volume 27, Issue 1, 2024, Pages 81-89]
PEGylated liposomes Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
Permeation Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
Personalized assessment Zinc oxide nanoparticle-reinforced sodium alginate/hydroxyapatite scaffolds for osteoporosis treatment in fragility fracture patients: Development and characterization using artificial neural networks (ANNs) modeling [Volume 27, Issue 12, 2024, Pages 1592-1603]
PGE2 Histopathological and biochemical evaluation of the protective efficacy of Prunus spinosa L. extract in a rat model of indomethacin-induced gastric ulcer [Volume 27, Issue 11, 2024, Pages 1464-1474]
Pharmacokinetic parameter How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
Pharmacokinetics Medicinal potential of embelin and its nanoformulations: An update on the molecular mechanism and various applications [Volume 27, Issue 10, 2024, Pages 1228-1242]
Pharmacologic actions Medicinal potential of embelin and its nanoformulations: An update on the molecular mechanism and various applications [Volume 27, Issue 10, 2024, Pages 1228-1242]
Pharmacological action Saffron An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
Pharmacology Novel drug candidates against antibiotic-resistant microorganisms: A review [Volume 27, Issue 2, 2024, Pages 134-150]
Phytochemicals Recent advancements in the role of phytochemicals and Medicinal plants in prophylaxis and management of Alzheimer’s disease [Volume 27, Issue 11, 2024, Pages 1357-1369]
Phytochemicals Targeting autophagy for breast cancer prevention and therapy: From classical methods to phytochemical agents [Volume 27, Issue 12, 2024, Pages 1475-1491]
PI3K Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [Volume 27, Issue 6, 2024, Pages 761-767]
PI3K Corilagin inhibits angiotensin II-induced atrial fibrosis and fibrillation in mice through the PI3K-Akt pathway [Volume 27, Issue 6, 2024, Pages 717-724]
PI3K/Akt Crocin protects against endoplasmic reticulum stress-related tubular injury in diabetic nephropathy via the activation of the PI3K/AKT/Nrf2 pathway [Volume 27, Issue 4, 2024, Pages 439-446]
PI3K/AKT/FOXO/PPARγ- Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
PI3Kca gene The simultaneous use of CRISPR/Cas9 to knock out the PI3Kca gene with radiation to enhance radiosensitivity and inhibit tumor growth in breast cancer [Volume 27, Issue 12, 2024, Pages 1566-1573]
Pioglitazone Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
Plant extracts Comprehensive and updated review on anti-oxidant effects of Nigella sativa and its constituent, thymoquinone, in various disorders [Volume 27, Issue 8, 2024, Pages 923-951]
Plant extracts Stimulating effect of nanocurcumin and crocin on proliferation and pluripotency of bone marrow-derived mesenchymal stem cells [Volume 27, Issue 9, 2024, Pages 1187-1196]
Platelet type 12-lipoxygease Baicalein blocked gastric cancer cell proliferation and invasion through modulated platelet type 12-lipoxygenase [Volume 27, Issue 12, 2024, Pages 1574-1582]
PLUSCOM Enhancement of the immunogenicity of a Mycobacterium tuberculosis fusion protein using ISCOMATRIX and PLUSCOM nano-adjuvants as prophylactic vaccine after nasal administration in mice [Volume 27, Issue 1, 2024, Pages 24-30]
Polycaprolactone Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
Polycaprolactone Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
Polycystic Ovarian Syndrome Revitalizing polycystic ovary syndrome: The therapeutic impact of low-dose ∆9 tetrahydrocannabinol through reduction of oxidative stress and modulation of macrophage polarization [Volume 27, Issue 8, 2024, Pages 1040-1049]
Polyethyleneimine Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
Polyethylenimine Lactosylated lipid calcium phosphate-based nanoparticles: A promising approach for efficient DNA delivery to hepatocytes [Volume 27, Issue 8, 2024, Pages 952-958]
Polyherbal extract Polyherbal extract improves glycometabolic control in alloxan-induced diabetic rats via down-regulating the MAPK/JNK pathway, modulating Nrf-2/Keap-1 expression, and stimulating insulin signaling [Volume 27, Issue 2, 2024, Pages 170-179]
Polystyrene microplastic Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice [Volume 27, Issue 12, 2024, Pages 1515-1528]
Polyvinyl alcohol Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes [Volume 27, Issue 10, 2024, Pages 1268-1275]
Potassium channels Beta-adrenergic receptor stimulation, histamine receptor inhibition, and potassium channel opening contribute to the relaxant effects of crocetin on airway smooth muscle [Volume 27, Issue 10, 2024, Pages 1317-1322]
Preeclampsia Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
Prefrontal cortex Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
Prenatal stress Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring [Volume 27, Issue 9, 2024, Pages 1115-1123]
Presbycusis Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
Presenilin-1 High-intensity interval training combined with cannabidiol supplementation improves cognitive impairment by regulating the expression of apolipoprotein E, presenilin-1, and glutamate proteins in a rat model of amyloid β-induced Alzheimer’s disease [Volume 27, Issue 12, 2024, Pages 1583-1591]
Prevention Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
Prevention Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
Probiotics Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
Programmed cell death Significance of genotypes and resistance status of Mycobacterium tuberculosis strains in gene expression of apoptosis cell death and inflammatory pathways in A549 lung epithelial cell line [Volume 27, Issue 7, 2024, Pages 825-831]
Prohormone convertase Prolonged stress alters the PC1/PC2 ratio in the rat lateral hypothalamus, implicating impaired orexin maturation [Volume 27, Issue 8, 2024, Pages 1059-1066]
Proliferation Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
Proliferation Evaluation of bioactive extract nanoparticles on pulp stem cell behavior relevant to dental care using chemical composition of gelatin-Arabian gum nano polymer [Volume 27, Issue 8, 2024, Pages 975-984]
Proliferation Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system [Volume 27, Issue 10, 2024, Pages 1251-1259]
Propolis Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
Propolis Inactivated herpes simplex virus-1 vaccine formulated in aqueous and alcoholic extracts of propolis boosts cellular and IgG responses [Volume 27, Issue 9, 2024, Pages 1209-1213]
Prostatic neoplasm Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
Protein kinase C θ Deletion of protein kinase C θ attenuates hepatic ischemia/reperfusion injury and further elucidates its mechanism in pathophysiology [Volume 27, Issue 10, 2024, Pages 1323-1330]
Prunus spinosa Histopathological and biochemical evaluation of the protective efficacy of Prunus spinosa L. extract in a rat model of indomethacin-induced gastric ulcer [Volume 27, Issue 11, 2024, Pages 1464-1474]
Pseudogenes Introduction of LPIN1 as a potential diagnostic and prognostic biomarker for gastric cancer via integrative bioinformatics analysis of a competing endogenous RNA network and experimental validation [Volume 27, Issue 11, 2024, Pages 1456-1463]
PTEN protein Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
Pueraria Huangqi Gegen decoction ameliorates alcohol-induced cognitive dysfunction via attenuating oxidative stress and enhancing blood-brain barrier integrity in rats through the Keap1-Nrf2/HO-1 signaling pathway [Volume 27, Issue 10, 2024, Pages 1331-1339]
Pulmonary Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
Pulmonary arterial- hypertension Isorhamnetin alleviates symptoms and inhibits oxidative stress levels in rats with pulmonary arterial hypertension [Volume 27, Issue 12, 2024, Pages 1616-1623]
Pulmonary artery smooth muscle cells Cited2 inhibited hypoxia-induced proliferation and migration of PASMCs via the TGF-β1/Cited2/PPARγ pathway [Volume 27, Issue 4, 2024, Pages 509-517]
Pulp stem cells Evaluation of bioactive extract nanoparticles on pulp stem cell behavior relevant to dental care using chemical composition of gelatin-Arabian gum nano polymer [Volume 27, Issue 8, 2024, Pages 975-984]
Pyroptosis Antiarrhythmic potentials of irisin in ischemia/reperfusion injury of diabetic rats through modulating mitochondria-endoplasmic reticulum interaction and inhibiting pyroptosis [Volume 27, Issue 11, 2024, Pages 1440-1446]
Pyroptosis Genistein inhibits the release of pro-inflammatory substances from macrophages by suppressing potassium loss- and ROS-mediated caspase-1/gasdermin D pathway activation and pyroptotic cell lysis [Volume 27, Issue 12, 2024, Pages 1506-1514]

R

Rabdomyolysis Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
Radiation The simultaneous use of CRISPR/Cas9 to knock out the PI3Kca gene with radiation to enhance radiosensitivity and inhibit tumor growth in breast cancer [Volume 27, Issue 12, 2024, Pages 1566-1573]
Rat Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
Rat Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
Rat Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
Rat Prolonged stress alters the PC1/PC2 ratio in the rat lateral hypothalamus, implicating impaired orexin maturation [Volume 27, Issue 8, 2024, Pages 1059-1066]
Rat Effect of mild gestational diabetes mellitus on histological, ultrastructural, and quantitative morphometric alterations of rat fetal liver [Volume 27, Issue 11, 2024, Pages 1405-1409]
Rat Regenerative role of mast cells and mesenchymal stem cells in histopathology of the sciatic nerve and tibialis cranialis muscle, following denervation in rats [Volume 27, Issue 12, 2024, Pages 1536-1546]
Rat Evening primrose oil ameliorates tissue architecture, apoptosis, and oxidative stress in the pancreas of diabetic rats: Possible role of miR-21 [Volume 27, Issue 12, 2024, Pages 1558-1565]
Rats Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
Rats L-Arginine-induced acute pancreatitis and its associated lung injury in rats: Down-regulation of TLR-4/MAPK-p38/JNK signaling pathway via Ginkgo biloba extract EGb 761 [Volume 27, Issue 8, 2024, Pages 959-966]
Reactive Oxygen Species TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
Reactive oxygen species - (ROS) Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]
Recombinant FVIII Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia [Volume 27, Issue 6, 2024, Pages 747-754]
Regeneration Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system [Volume 27, Issue 10, 2024, Pages 1251-1259]
Regeneration Regenerative role of mast cells and mesenchymal stem cells in histopathology of the sciatic nerve and tibialis cranialis muscle, following denervation in rats [Volume 27, Issue 12, 2024, Pages 1536-1546]
Regenerative medicine Stimulating effect of nanocurcumin and crocin on proliferation and pluripotency of bone marrow-derived mesenchymal stem cells [Volume 27, Issue 9, 2024, Pages 1187-1196]
Regenerative medicine Vitamin C, doxycycline, and azithromycin (VDA) targeted changes in cellular senescence-related genes in human adipose-derived mesenchymal stem cells [Volume 27, Issue 11, 2024, Pages 1380-1388]
Regulatory T cells Co-administration of 1,25-dihydroxyvitamin D3 and infliximab improves colitis in mice by modulating Treg differentiation [Volume 27, Issue 9, 2024, Pages 1172-1179]
Relaxant effects Beta-adrenergic receptor stimulation, histamine receptor inhibition, and potassium channel opening contribute to the relaxant effects of crocetin on airway smooth muscle [Volume 27, Issue 10, 2024, Pages 1317-1322]
Release Genistein inhibits the release of pro-inflammatory substances from macrophages by suppressing potassium loss- and ROS-mediated caspase-1/gasdermin D pathway activation and pyroptotic cell lysis [Volume 27, Issue 12, 2024, Pages 1506-1514]
Release kinetics Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
Renal injury Metabolomics analysis reveals a protective effect of hydroxycitric acid on calcium oxalate-induced kidney injury [Volume 27, Issue 10, 2024, Pages 1243-1250]
Renin angiotensin aldosterone system Cardiovascular effect of preeclampsia upon offspring development: Are (Pro) renin-renin receptor ((P)RR) and gender related? [Volume 27, Issue 5, 2024, Pages 621-629]
Renin–angiotensin system Effects of alamandine on monocrotaline-induced pulmonary hypertension in rats [Volume 27, Issue 4, 2024, Pages 500-508]
Reperfusion Antiarrhythmic potentials of irisin in ischemia/reperfusion injury of diabetic rats through modulating mitochondria-endoplasmic reticulum interaction and inhibiting pyroptosis [Volume 27, Issue 11, 2024, Pages 1440-1446]
Reproduction All-trans retinoic acid and fibroblast growth factor-2 enhance the fertility rate and embryo development in polycystic ovary syndrome mouse model [Volume 27, Issue 4, 2024, Pages 418-424]
Reproductive Hormones Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
Rescue therapy Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
Resistin Injection of resistin into the paraventricular nucleus produces a cardiovascular response that may be mediated by glutamatergic transmission in the rostral ventrolateral medulla [Volume 27, Issue 1, 2024, Pages 39-48]
Resveratrol Resveratrol treatment ameliorates hepatic damage via the TGF-β/SMAD signaling pathway in a phenobarbital/CCl4-induced hepatic fibrosis model [Volume 27, Issue 9, 2024, Pages 1124-1133]
Rheumatoid arthritis Synthesized diterpene lactone derivative attenuated Freund’s complete adjuvant-induced arthritis in Wistar rats [Volume 27, Issue 9, 2024, Pages 1197-1208]
Right ventricular - hypertrophy Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
Rosmarinic acid Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
Royal jelly Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice [Volume 27, Issue 12, 2024, Pages 1515-1528]
Royal jelly (RJ) Royal jelly induces ROS-mediated apoptosis in acute lymphoblastic leukemia (ALL)-derived Nalm-6 cells: Shedding light on novel therapeutic approaches for ALL [Volume 27, Issue 7, 2024, Pages 801-812]

S

Safranal An overview of pharmacological effects of Crocus sativus and its constituents [Volume 27, Issue 4, 2024, Pages 391-417]
Safranal Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by PQ aerosol in rats [Volume 27, Issue 5, 2024, Pages 640-646]
Salidroside Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome [Volume 27, Issue 3, 2024, Pages 297-303]
Salvin Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
Saroglitazar Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
Saroglitazar Curcumin and saroglitazar attenuate diet-induced nonalcoholic steatohepatitis by activating the Nrf2 pathway and suppressing ERK1/2 signaling [Volume 27, Issue 8, 2024, Pages 1015-1022]
Saroglitazar Suppression of TGF-β/Smad3 signaling pathway by Capparis spinosa and quercetin in a rat model of nonalcoholic steatohepatitis [Volume 27, Issue 9, 2024, Pages 1096-1104]
Saroglitazar Saroglitazar suppresses KIM-1 and type IV collagen in high fat diet and low-dose streptozotocin-induced diabetic nephropathy in Wistar rats [Volume 27, Issue 11, 2024, Pages 1447-1455]
SARS-CoV-2 Application of methylene blue for the prevention and treatment of COVID-19, a narrative review [Volume 27, Issue 7, 2024, Pages 780-792]
SASP (-)-α-Bisabolol inhibits D-Gal-induced HSF cellular senescence in vitro and prevents skin aging in vivo by reducing SASP [Volume 27, Issue 9, 2024, Pages 1105-1114]
Sciatic nerve Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
Sciatic nerve Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis [Volume 27, Issue 5, 2024, Pages 596-602]
Sea buckthorn Isorhamnetin alleviates symptoms and inhibits oxidative stress levels in rats with pulmonary arterial hypertension [Volume 27, Issue 12, 2024, Pages 1616-1623]
Second brain injury Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
Secretome Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
Selenium Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes [Volume 27, Issue 10, 2024, Pages 1268-1275]
Senescence Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
Sepsis Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
Sepsis Alleviating sepsis: Revealing the protective role of costunolide in a cecal ligation and puncture rat model [Volume 27, Issue 5, 2024, Pages 567-576]
Sepsis N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
Serotype Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
Sialyl lewis X Fucosyltransferase 3 and 8 promote the metastatic capacity of cancer stem-like cells via CD15s and E-cadherin in esophageal cancer [Volume 27, Issue 8, 2024, Pages 985-995]
Signaling pathway Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
Silymarin Protective effects of silymarin-loaded chitosan nanoparticles in the diet-induced hyperlipidemia rat model [Volume 27, Issue 6, 2024, Pages 725-732]
SIRT1 Alpha-mangostin decreases high glucose-induced damage on human umbilical vein endothelial cells by increasing autophagic protein expression [Volume 27, Issue 1, 2024, Pages 90-96]
Sirt3 N-acetylcysteine protects septic acute kidney injury by inhibiting SIRT3-mediated mitochondrial dysfunction and apoptosis [Volume 27, Issue 7, 2024, Pages 850-856]
Skin aging Potential antiaging activity of secretome gel of human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) in UV-induced mice models [Volume 27, Issue 7, 2024, Pages 868-878]
Skin aging (-)-α-Bisabolol inhibits D-Gal-induced HSF cellular senescence in vitro and prevents skin aging in vivo by reducing SASP [Volume 27, Issue 9, 2024, Pages 1105-1114]
Skin neoplasms Design and fabrication of alginate hydrogel nanohybrid as a promising cancer treatment [Volume 27, Issue 6, 2024, Pages 695-705]
Skin tissue engineering An in situ forming gelatin-based hydrogel loaded with soluble amniotic membrane promotes full-thickness wound regeneration in rats [Volume 27, Issue 8, 2024, Pages 1005-1014]
Sleep deprivation Luteolin reversed anxiety and depressive-like behavior via modulation of the NF-κB/NLRP3 inflammasome axis in the hippocampus of rats subjected to sleep deprivation [Volume 27, Issue 8, 2024, Pages 1050-1058]
Slit guidance ligand 3 SLIT3 promotes cardiac fibrosis and differentiation of cardiac fibroblasts by RhoA/ROCK1 signaling pathway [Volume 27, Issue 7, 2024, Pages 832-840]
Smad2/3 Dexmedetomidine protects against sepsis-induced lung injury through autophagy and Smad2/3 signaling pathway [Volume 27, Issue 4, 2024, Pages 453-460]
SMAD Proteins Resveratrol treatment ameliorates hepatic damage via the TGF-β/SMAD signaling pathway in a phenobarbital/CCl4-induced hepatic fibrosis model [Volume 27, Issue 9, 2024, Pages 1124-1133]
Sodium alginate Comparison of different hydroxyapatite composites for bone tissue repair: In vitro and in vivo analyses [Volume 27, Issue 9, 2024, Pages 1155-1161]
Sodium arsenite Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt2/FOXO1 pathway [Volume 27, Issue 4, 2024, Pages 485-491]
Sodium arsenite Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
Sodium carboxymethylcellulose Injectable multifunctional hydrogel containing Sphingosine 1-phosphate and human acellular amniotic membrane for skin wound healing [Volume 27, Issue 9, 2024, Pages 1134-1147]
Sodium dichloroacetate Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
Sodium iodate Classification, location, and intensity of granules in retinal pigment epithelium following sodium iodate injection in rat animal model [Volume 27, Issue 3, 2024, Pages 286-296]
Solid lipid nanoparticle How do lipid-based drug delivery systems affect the pharmacokinetic and tissue distribution of amiodarone? A comparative study of liposomes, solid lipid nanoparticles, and nanoemulsions [Volume 27, Issue 7, 2024, Pages 857-867]
Solid lipid nanoparticle Quality by Design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation [Volume 27, Issue 7, 2024, Pages 904-913]
Somatosensory cortex Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
Sox11 Possible role of Sox11 in a rat model of surgical brain injury [Volume 27, Issue 7, 2024, Pages 888-894]
Spatial Memory Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring [Volume 27, Issue 9, 2024, Pages 1115-1123]
Sperm analyses Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
Spermatogenesis Effects of diabetes-induced hyperglycemia on epigenetic modifications and DNA packaging and methylation during spermatogenesis; A narrative review [Volume 27, Issue 1, 2024, Pages 3-11]
Spexin Effects of N-acetylcysteine on spexin immunoreactivity in kidney tissues of rats treated with adriamycin [Volume 27, Issue 2, 2024, Pages 233-240]
Sphingosine 1-phosphate Injectable multifunctional hydrogel containing Sphingosine 1-phosphate and human acellular amniotic membrane for skin wound healing [Volume 27, Issue 9, 2024, Pages 1134-1147]
Spinal cord injury Testosterone signaling pathways for reducing neuropathic pain in a rat model of spinothalamic tract lesion [Volume 27, Issue 11, 2024, Pages 1417-1422]
Spring Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates diabetes-induced acute lung injury via activating Nrf2/ HO-1 [Volume 27, Issue 11, 2024, Pages 1423-1429]
Staphylococcus aureus Suppression of Staphylococcus aureus biofilm formation under a short-term impact of low-intensity direct current in vitro and in a rat model of implant-associated osteomyelitis [Volume 27, Issue 2, 2024, Pages 247-255]
STAT6 Improvement of 5-fluorouracil chemosensitivity in colorectal cancer cells by siRNA-mediated silencing of STAT6 oncogene [Volume 27, Issue 4, 2024, Pages 475-484]
Stem cells Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes [Volume 27, Issue 10, 2024, Pages 1268-1275]
Stomach Neoplasms Introduction of LPIN1 as a potential diagnostic and prognostic biomarker for gastric cancer via integrative bioinformatics analysis of a competing endogenous RNA network and experimental validation [Volume 27, Issue 11, 2024, Pages 1456-1463]
Stomach Neoplasms THADA protein THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
Streptococcus pneumoniae Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
Streptozocin Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes [Volume 27, Issue 10, 2024, Pages 1268-1275]
Streptozotocin Saroglitazar suppresses KIM-1 and type IV collagen in high fat diet and low-dose streptozotocin-induced diabetic nephropathy in Wistar rats [Volume 27, Issue 11, 2024, Pages 1447-1455]
Structure-activity- relationship Medicinal potential of embelin and its nanoformulations: An update on the molecular mechanism and various applications [Volume 27, Issue 10, 2024, Pages 1228-1242]
Subchondral bone Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
Sulforaphane Effect of electroacupuncture combined with sulforaphane in the treatment of sarcopenia in SAMP8 mice [Volume 27, Issue 5, 2024, Pages 560-566]
Surface proteins Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
Surgery Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]

T

Tamoxifen Underlying anti-cancer mechanisms of histone deacetylase (HDAC) inhibitors in tamoxifen-resistant breast cancer cells [Volume 27, Issue 6, 2024, Pages 775-779]
Targeted therapy Targeting autophagy for breast cancer prevention and therapy: From classical methods to phytochemical agents [Volume 27, Issue 12, 2024, Pages 1475-1491]
Taurine Taurine supplementation decreases fat accumulation by suppressing FAS and enhancing ATGL through the ATGL pathway [Volume 27, Issue 12, 2024, Pages 1529-1535]
TCS OX2 29 Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [Volume 27, Issue 4, 2024, Pages 461-465]
Testicular toxicity Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology [Volume 27, Issue 4, 2024, Pages 466-474]
Testicular toxicity Therapeutic potential of virgin coconut oil in mitigating sodium benzoate- model of male infertility: Role of Nrf2/Hmox-1/NF-kB signaling pathway [Volume 27, Issue 5, 2024, Pages 543-551]
Testicular toxicity Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways [Volume 27, Issue 5, 2024, Pages 603-610]
Testicular toxicity Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice [Volume 27, Issue 12, 2024, Pages 1515-1528]
Testis Preventive effects of quercetin against inflammation and apoptosis in cyclophosphamide-induced testicular damage [Volume 27, Issue 5, 2024, Pages 647-656]
Testis Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [Volume 27, Issue 6, 2024, Pages 678-684]
Testis Effect of thymoquinone on NRF2 / NF-kB / MAPK pathway in methotrexate-induced rat testis injury [Volume 27, Issue 11, 2024, Pages 1410-1416]
Testosterone Testosterone signaling pathways for reducing neuropathic pain in a rat model of spinothalamic tract lesion [Volume 27, Issue 11, 2024, Pages 1417-1422]
Tetramethylpyrazine Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
TFAM Tetramethylpyrazine protects mitochondrial function by up-regulation of TFAM and inhibition of neuronal apoptosis in a rat model of surgical brain injury [Volume 27, Issue 3, 2024, Pages 352-359]
TGFβ Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [Volume 27, Issue 2, 2024, Pages 241-246]
TGF-β/Smad3 Suppression of TGF-β/Smad3 signaling pathway by Capparis spinosa and quercetin in a rat model of nonalcoholic steatohepatitis [Volume 27, Issue 9, 2024, Pages 1096-1104]
Th1 Inactivated herpes simplex virus-1 vaccine formulated in aqueous and alcoholic extracts of propolis boosts cellular and IgG responses [Volume 27, Issue 9, 2024, Pages 1209-1213]
Th17 cell Curcumin chitosan microspheres regulate Th17/Treg balance via IGF2BP1- mediated m6A modification of LRP5 in ulcerative colitis [Volume 27, Issue 10, 2024, Pages 1276-1283]
Thalamus TRPV1 Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse [Volume 27, Issue 1, 2024, Pages 66-73]
Therapeutic biomarker Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
Therapeutics Dysregulated microRNAs in prostate cancer: In silico prediction and in vitro validation [Volume 27, Issue 5, 2024, Pages 611-620]
Therapeutic targets Novel drugs affecting diabetic peripheral neuropathy [Volume 27, Issue 6, 2024, Pages 657-670]
Thymoquinone Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
Thymoquinone Comprehensive and updated review on anti-oxidant effects of Nigella sativa and its constituent, thymoquinone, in various disorders [Volume 27, Issue 8, 2024, Pages 923-951]
Thymoquinone Thymoquinone: A comprehensive review of its potential role as a monotherapy for metabolic syndrome [Volume 27, Issue 10, 2024, Pages 1214-1227]
Thymoquinone Effect of thymoquinone on NRF2 / NF-kB / MAPK pathway in methotrexate-induced rat testis injury [Volume 27, Issue 11, 2024, Pages 1410-1416]
Tissue engineering Synthesis of bone biocompatible implants using human adipose-derived mesenchymal stem cells (hADMSCs) and PCL/laminin scaffold substrate [Volume 27, Issue 2, 2024, Pages 188-194]
TLR4/NF-κB/IKB α pathway Deletion of protein kinase C θ attenuates hepatic ischemia/reperfusion injury and further elucidates its mechanism in pathophysiology [Volume 27, Issue 10, 2024, Pages 1323-1330]
TNF-α Histopathological and biochemical evaluation of the protective efficacy of Prunus spinosa L. extract in a rat model of indomethacin-induced gastric ulcer [Volume 27, Issue 11, 2024, Pages 1464-1474]
Toll-like receptor 4 Protective effect of 1, 8-cineole (eucalyptol) against lead-induced liver injury by ameliorating oxidative stress and inflammation and modulating TLR4/MyD88/NF-κB signaling [Volume 27, Issue 10, 2024, Pages 1293-1299]
Toll-like receptor-4 Sodium dichloroacetate improves migration ability by suppressing LPS-induced inflammation in HTR-8/SVneo cells via the TLR4/NF-κB pathway [Volume 27, Issue 1, 2024, Pages 16-23]
Toll-like receptors Role of cell surface proteins and toll-like receptors in the pathogenesis of Streptococcus pneumoniae [Volume 27, Issue 2, 2024, Pages 214-222]
TOR Serine-Threonine- Kinases THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway [Volume 27, Issue 2, 2024, Pages 195-202]
Total flavonoids of - Selaginella tamariscina (P.Beauv.) Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates diabetes-induced acute lung injury via activating Nrf2/ HO-1 [Volume 27, Issue 11, 2024, Pages 1423-1429]
Toxicity Propolis and its therapeutic effects on renal diseases: A review [Volume 27, Issue 4, 2024, Pages 383-390]
Transfection Synthesis and evaluation of gene delivery vectors based on PEI-modified metal-organic framework (MOF) nanoparticles [Volume 27, Issue 2, 2024, Pages 203-213]
Transforming growth factor β/small mother against decapentaplegic (TGF-β/SMAD) signalling Resveratrol treatment ameliorates hepatic damage via the TGF-β/SMAD signaling pathway in a phenobarbital/CCl4-induced hepatic fibrosis model [Volume 27, Issue 9, 2024, Pages 1124-1133]
Transient receptor potential channels TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
Translational medicine Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine [Volume 27, Issue 2, 2024, Pages 122-133]
Transplantation Gliosis induction on locus coeruleus in a living liver donor experimental model: A brief review [Volume 27, Issue 1, 2024, Pages 12-15]
Trans-sodium crocetinate Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells [Volume 27, Issue 6, 2024, Pages 768-774]
Treatment Age-related hearing loss: An updated and comprehensive review of the interventions [Volume 27, Issue 3, 2024, Pages 256-269]
Treg cell Curcumin chitosan microspheres regulate Th17/Treg balance via IGF2BP1- mediated m6A modification of LRP5 in ulcerative colitis [Volume 27, Issue 10, 2024, Pages 1276-1283]
Trend analysis Febuxostat attenuates secondary brain injury caused by cerebral hemorrhage through inhibiting inflammatory pathways [Volume 27, Issue 6, 2024, Pages 740-746]
Tropisetron 5-HT3 antagonist, tropisetron, ameliorates age-related renal injury induced by D-galactose in male mice: Up-regulation of sirtuin 1 [Volume 27, Issue 5, 2024, Pages 577-587]
TRPA1 cation channel TRPA1 as a promising target in ischemia/reperfusion: A comprehensive review [Volume 27, Issue 3, 2024, Pages 270-278]
Trpm Effect of thymoquinone on transient receptor potential melastatin (TRPM) channels in rats with liver ischemia reperfusion model in rats [Volume 27, Issue 3, 2024, Pages 319-325]
Tubal factor infertility Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation [Volume 27, Issue 6, 2024, Pages 685-694]
Tumor necrosis factors Attenuation of acrylamide-induced neurotoxicity by supplementation of sitagliptin in Wistar rats [Volume 27, Issue 3, 2024, Pages 311-318]
Tumor progression Candidiasis in breast cancer: Tumor progression or not? [Volume 27, Issue 11, 2024, Pages 1346-1356]
Tumor suppressor protein p53 Isolated Lactobacillus fermentum Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway [Volume 27, Issue 4, 2024, Pages 447-452]
Tumor suppressor protein- p53 Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway [Volume 27, Issue 5, 2024, Pages 588-595]
Type 1 diabetes Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway [Volume 27, Issue 1, 2024, Pages 31-38]
Type IV collagen Saroglitazar suppresses KIM-1 and type IV collagen in high fat diet and low-dose streptozotocin-induced diabetic nephropathy in Wistar rats [Volume 27, Issue 11, 2024, Pages 1447-1455]

V

Vaccine potency Inactivated herpes simplex virus-1 vaccine formulated in aqueous and alcoholic extracts of propolis boosts cellular and IgG responses [Volume 27, Issue 9, 2024, Pages 1209-1213]
Valproic acid Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus [Volume 27, Issue 3, 2024, Pages 335-342]
Vascular calcification Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
Vascular Endothelial Growth Factor Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
Vascular endothelial growth - factors Assessment of the proliferative and angiogenic effects of the synthetic cannabinoid (R)-5-fluoro ADB on human cerebral microvascular endothelial cells [Volume 27, Issue 3, 2024, Pages 304-310]
Vascular injuries Metformin alleviates bevacizumab-induced vascular endothelial injury in mice through growth differentiation factor 15 upregulation [Volume 27, Issue 3, 2024, Pages 343-351]
VEGF Effects of dose-dependent chronic caffeine consumption in a rat burn wound model: Histopathological and immunohistochemical evaluation [Volume 27, Issue 9, 2024, Pages 1180-1186]
VEGFR2 Apatinib has anti-tumor effects and induces autophagy in lung cancer cells with high expression of VEGFR-2 [Volume 27, Issue 11, 2024, Pages 1370-1379]
Vitamin B12 Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats [Volume 27, Issue 6, 2024, Pages 733-739]
Vitamin C Vitamin C, doxycycline, and azithromycin (VDA) targeted changes in cellular senescence-related genes in human adipose-derived mesenchymal stem cells [Volume 27, Issue 11, 2024, Pages 1380-1388]
Vitamin D Co-administration of 1,25-dihydroxyvitamin D3 and infliximab improves colitis in mice by modulating Treg differentiation [Volume 27, Issue 9, 2024, Pages 1172-1179]
Vitamin E Carnosic acid mitigates doxorubicin-induced cardiac toxicity: Evidence from animal and cell model investigations [Volume 27, Issue 4, 2024, Pages 425-438]
Voluntary exercise Voluntary exercise improves pulmonary inflammation through NF-κB and Nrf-2 in type 2 diabetic male rats [Volume 27, Issue 1, 2024, Pages 74-80]

W

White Matter Neuroprotective effects of rosemary extract on white matter of prefrontal cortex in old rats [Volume 27, Issue 4, 2024, Pages 518-523]
WNT Rosmarinic acid ameliorates the complications of monocrotaline-induced right ventricular hypertrophy on the left ventricle: Investigating the signaling pathway of Wnt/β-catenin in the heart [Volume 27, Issue 7, 2024, Pages 841-849]
Wnt5a Wnt5a deficiency in osteocalcin-expressing cells could not alleviate the osteoarthritic phenotype in a mouse model of post-traumatic osteoarthritis [Volume 27, Issue 6, 2024, Pages 671-677]
Wnt signaling pathway Regeneration of amputated mice digit tips by including Wnt signaling pathway with CHIR99021 and IWP-2 chemicals in limb organ culture system [Volume 27, Issue 10, 2024, Pages 1251-1259]
Wound healing Wound healing effects of dexpanthenol-loaded core/shell electrospun nanofibers: Implication of oxidative stress in wound healing [Volume 27, Issue 1, 2024, Pages 97-106]
Wound healing Fabrication and evaluation of the regenerative effect of a polycaprolactone/chitosan nanofibrous scaffold containing bentonite nanoparticles in a rat model of deep second-degree burn injury [Volume 27, Issue 2, 2024, Pages 223-232]
Wound healing An in situ forming gelatin-based hydrogel loaded with soluble amniotic membrane promotes full-thickness wound regeneration in rats [Volume 27, Issue 8, 2024, Pages 1005-1014]
Wound healing Injectable multifunctional hydrogel containing Sphingosine 1-phosphate and human acellular amniotic membrane for skin wound healing [Volume 27, Issue 9, 2024, Pages 1134-1147]
Wound healing Effects of dose-dependent chronic caffeine consumption in a rat burn wound model: Histopathological and immunohistochemical evaluation [Volume 27, Issue 9, 2024, Pages 1180-1186]

Iranian Journal of Basic Medical Sciences

Keyword Index

A

B

C

D

E

F

G

H

I

K

L

M

N

O

P

Q

R

S

T

U

V

W

Y

Z