Keyword Index

A

  • Acinetobacter baumannii Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [Volume 25, Issue 2, 2022, Pages 239-244]
  • Acinetobacter baumannii Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
  • Acrylamide Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
  • Actins Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
  • Acupuncture points injection Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
  • Acute kidney injury Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
  • Acute kidney injury Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]
  • Acute kidney injury Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
  • Acute kidney injury Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
  • Acute lung injury Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
  • Acute lung injury Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
  • Acute lung injury Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
  • Addiction Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
  • Adipogenesis Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
  • Adipose-derived mesenchymal stem cells Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
  • Adjuvant PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
  • Aerobic training Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
  • Aggression Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
  • Aging The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
  • Aging Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
  • AKI Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
  • ALL MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
  • Allergy 6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation [Volume 25, Issue 5, 2022, Pages 629-634]
  • Alum Adjuvant Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
  • Alzheimer Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
  • Alzheimer’s disease Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
  • Ambroxol Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
  • Aminoglycoside Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [Volume 25, Issue 1, 2022, Pages 121-125]
  • Amnesia Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
  • AMPK Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
  • Amygdala Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
  • Angiogenesis In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
  • Angiogenesis Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [Volume 25, Issue 4, 2022, Pages 506-513]
  • Angiogenesis Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
  • Angiogenesis inhibitors In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
  • Angiotensin II LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
  • Angiotensin II Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
  • Angiotensin receptor Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
  • Anti-apoptotic Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
  • Anti-apoptotic Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]
  • Antibacterial agents Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
  • Antibiotic resistance Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
  • Antibiotic resistance High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
  • Anticonvulsant New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
  • Anti-inflammatory Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]
  • Anti-inflammatory Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
  • Anti-inflammatory Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
  • Anti-inflammatory New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
  • Antimicrobial activity Ib-AMP4 antimicrobial peptide as a treatment for skin and systematic infection of methicillin-resistant Staphylococcus aureus (MRSA) [Volume 25, Issue 2, 2022, Pages 232-238]
  • Antineoplastic agents Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
  • Antineoplastic agents A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
  • Antineoplastic protocols Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
  • Anti-oxidant Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [Volume 25, Issue 1, 2022, Pages 121-125]
  • Anti-oxidant Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
  • Anti-oxidant Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article [Volume 25, Issue 12, 2022, Pages 1402-1415]
  • Anti-oxidant Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
  • Anti-oxidant Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
  • Anti-oxidant New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
  • Anti-Oxidants Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
  • Anti-Oxidants Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
  • Anti-Oxidants Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
  • Anti-Oxidants A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
  • Anti-Oxidants Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
  • Anti-Oxidants MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
  • Antioxidant therapy Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]
  • Anti-PCSK9 antibody Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]
  • Antiproliferation Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]
  • Anti-tumor activity Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
  • Anti-virulent strategy Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
  • Anxiety Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
  • Apoptosis MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
  • Apoptosis Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
  • Apoptosis Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
  • Apoptosis Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
  • Apoptosis Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
  • Apoptosis Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
  • Apoptosis Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
  • Apoptosis Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
  • Apoptosis 1,3,5-triazines inhibit osteosarcoma and avert lung metastasis in a patient-derived orthotopic xenograft mouse model with favorable pharmacokinetics [Volume 25, Issue 3, 2022, Pages 295-301]
  • Apoptosis Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
  • Apoptosis Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
  • Apoptosis Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
  • Apoptosis Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
  • Apoptosis Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
  • Apoptosis Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
  • Apoptosis Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
  • Apoptosis Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
  • Apoptosis Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
  • Apoptosis Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
  • Apoptosis TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
  • Argatroban Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]
  • Arginine In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
  • Artificial organs Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
  • Asia In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
  • Astaxanthin Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
  • Asthma C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
  • Asthma Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice [Volume 25, Issue 10, 2022, Pages 1267-1274]
  • Astragaloside IV Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
  • Astrocyte Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
  • Astrogliosis Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
  • Atherosclerosis Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
  • Atherosclerosis Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
  • ATLL TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
  • Atractylodes Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
  • Atrial fibrillation LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
  • Autolysin Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
  • Autophagy Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
  • Autophagy Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
  • Autophagy Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
  • Autophagy Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
  • Autophagy Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
  • Autophagy Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells [Volume 25, Issue 11, 2022, Pages 1364-1372]

B

  • Baicalein An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
  • Baicalin An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
  • Bax Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
  • Bax protein Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice [Volume 25, Issue 7, 2022, Pages 890-896]
  • Bcl-2 Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
  • Bcl-2 Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
  • Bead Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
  • Behavioral tests Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
  • Behavior tests Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome [Volume 25, Issue 11, 2022, Pages 1308-1316]
  • Benzalkonium chloride,Benzethonium chloride High prevalence and expression of antiseptic resistance genes among infectious t037/ST239 methicillin-resistant Staphylococcus aureus (MRSA) strains in North Khorasan Province, Iran [Volume 25, Issue 6, 2022, Pages 775-780]
  • Berberine Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
  • Betulinic acid The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
  • Bifidobacterium Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
  • Bioactive peptides Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
  • Biodistribution Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
  • Biofilm Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]
  • Bioinformatics Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells [Volume 25, Issue 11, 2022, Pages 1364-1372]
  • Biomarkers Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
  • Biomarkers Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
  • Biomedical application Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
  • Bladder cancer Combination of T-DM1 and platinum-based chemotherapy in patient-derived xenograft models of muscle-invasive bladder cancer [Volume 25, Issue 7, 2022, Pages 816-821]
  • Blood Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
  • Blood-brain barrier Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
  • Blood coagulation factors Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]
  • BM C-kit+ HSCs Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
  • BMP2 Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]
  • Boldenone Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
  • Bone marrow mesenchymal stem cells Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells [Volume 25, Issue 11, 2022, Pages 1364-1372]
  • Boraginaceae Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
  • Botulinum Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
  • B-PEI Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
  • Brain barrier dysfunction Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
  • Brain damage Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
  • Brain-derived neurotrophic factor Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
  • Brain drug delivery Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
  • Brain Injuries Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
  • Brain Injuries Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
  • Brain ischemia Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
  • Brain ischemia Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
  • Breast Cancer Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
  • Breast Cancer Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
  • Breast Cancer In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]

C

  • Cabergolin Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
  • Caffeic acid Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
  • Calcium dobesilate Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
  • Calcium-sensing receptor Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]
  • Calorie restriction Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
  • Cancer MicroRNA-96: A therapeutic and diagnostic tumor marker [Volume 25, Issue 1, 2022, Pages 3-13]
  • Cancer An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
  • Cancer Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
  • Cancer Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [Volume 25, Issue 4, 2022, Pages 506-513]
  • Cannabinoid receptor Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
  • Cannabinoid receptors Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
  • Carbapenemase High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
  • Carbon tetrachloride Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
  • Carcinoma Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
  • Carcinoma Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
  • Cardenolides LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
  • Cardiac fibrosis Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
  • Cardiomyopathy Biliary cirrhosis-induced cardiac abnormality in rats: Interaction between Farnesoid-X-activated receptors and the cardiac uncoupling proteins 2 and 3 [Volume 25, Issue 1, 2022, Pages 126-133]
  • Cardiopulmonary - Resuscitation Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
  • Carvedilol Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
  • Carveol Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
  • Caspase-3 Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]
  • Catalase Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
  • Catalase The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
  • CCR8 Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
  • CD4+/CD8+ C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
  • Celastrol Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
  • Cell-based therapy Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
  • Cell cycle checkpoints Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
  • Cell death Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
  • Cell Proliferation MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
  • Cell therapy Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
  • Central nucleus of amygdala Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
  • Cerebral infarction Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
  • Cerebral toxicity Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
  • Cervical Cancer Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
  • Cervical Intraepithelial - neoplasia Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
  • Checkpoint inhibitors Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
  • Chemical toxic agent Ellagic acid Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article [Volume 25, Issue 12, 2022, Pages 1402-1415]
  • Chemotherapeutic resistance Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
  • Chitosan Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
  • Chlorhexidine gluconate High prevalence and expression of antiseptic resistance genes among infectious t037/ST239 methicillin-resistant Staphylococcus aureus (MRSA) strains in North Khorasan Province, Iran [Volume 25, Issue 6, 2022, Pages 775-780]
  • Chromone derivatives Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
  • Chronic inflammatory pain Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
  • Cigarette Smoking Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
  • Cilostazol Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
  • Circular RNA Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
  • Cisplatin Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
  • Cisplatin Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
  • Cisplatin Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
  • Citicoline Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
  • C-kit cells C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
  • Claudin-5 Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
  • Clearance Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]
  • Clinical trial Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
  • Clinical Trials Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
  • Cloning Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
  • Clostridium Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
  • CML Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
  • Cobalt Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
  • Cochlear synaptopathy Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
  • Coenzyme Q10 Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
  • Cognitive impairment Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]
  • Colistin Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
  • Collagen Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
  • Colon cancer Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
  • Colorectal cancer Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice [Volume 25, Issue 7, 2022, Pages 890-896]
  • Comfrey Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
  • Common bile duct ligation Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
  • Competing- endogenous - RNA Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
  • Conditioned medium Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
  • Conjugated linoleic acid Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
  • Constipation Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]
  • Contusion Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
  • Coronary Artery Disease Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
  • Coronary Stent Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
  • Coronary vessels Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
  • Corpus striatum Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
  • COVID-19 Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
  • COVID-19 In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
  • Creatine Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
  • Crocetin Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
  • Crocin Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
  • Crocin Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
  • Crocin Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
  • Crocin Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
  • Crocin Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
  • Crocin Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
  • Crocus Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
  • Crocus sativus Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
  • CTDSP1 protein MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
  • Cuprizone Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
  • Curcumol Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
  • Cyclin D Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
  • Cyclooxygenases Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]
  • CYP2C19 variants Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
  • Cysteine-rich transmembrane Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
  • Cytochrome P450 Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
  • Cytokine Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
  • Cytokine Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
  • Cytokines Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway [Volume 25, Issue 5, 2022, Pages 635-642]
  • Cytotoxicity effect Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]

D

  • Daidzein Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
  • Dapsone Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
  • Decoy receptor Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
  • Deep brain stimulation Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
  • Degradation Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
  • D-galactose Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
  • Diabesity Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
  • Diabetes Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
  • Diabetes Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
  • Diabetes A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
  • Diabetes The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]
  • Diabetes Mellitus Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]
  • Diabetes Mellitus Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
  • Diabetes Mellitus Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
  • Diabetes Mellitus LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
  • Diabetic foot Wound dressings incorporating microRNAs: Innovative therapy for diabetic wound treatment [Volume 25, Issue 9, 2022, Pages 1042-1044]
  • Diabetic nephropathy Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
  • Diabetic nephropathy Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
  • Diabetic nephropathy Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
  • Diagnosis MicroRNA-96: A therapeutic and diagnostic tumor marker [Volume 25, Issue 1, 2022, Pages 3-13]
  • Diarrhea Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]
  • Diclofenac Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
  • Diet Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
  • Diethylnitrosamine Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
  • Differentiation C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
  • Difficile Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
  • Diffusion Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
  • Dioscin Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]
  • Disease Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
  • Distant organ effect Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
  • DNA damage Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
  • Dopamine D2 receptor - antagonist Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
  • Dorsal root ganglion Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
  • Double-Strand Break Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
  • Dressings Wound dressings incorporating microRNAs: Innovative therapy for diabetic wound treatment [Volume 25, Issue 9, 2022, Pages 1042-1044]
  • Drug Delivery Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
  • Drug Delivery system Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
  • Drug metabolism Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
  • Drug-resistance Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
  • Dulaglutide Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
  • Dyslipidemia The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]

E

  • EAE model Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
  • Electrophysiological factors Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
  • Electrospinning Preparation of stable enteric folic acid-loaded microfiber using the electrospinning method [Volume 25, Issue 3, 2022, Pages 405-413]
  • Ellagic acid Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
  • Endocannabinoid Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
  • Endocannabinoids Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
  • Endometrium Investigation of the endometrial receptivity status in experimental hypothyroid-induced female rats [Volume 25, Issue 9, 2022, Pages 1077-1083]
  • Endoplasmic reticulum chaperone BiP Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
  • Endoplasmic reticulum stress Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
  • Energy metabolism Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
  • Enrichment analysis Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
  • Enteric Preparation of stable enteric folic acid-loaded microfiber using the electrospinning method [Volume 25, Issue 3, 2022, Pages 405-413]
  • Enterobacteriaceae High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
  • Enzyme-linked - immunosorbent assay (ELISA) New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
  • Epigallocatechin-3-gallate Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction [Volume 25, Issue 4, 2022, Pages 483-488]
  • Epilepsy Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
  • Epithelial-mesenchymal - transition LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
  • Epithelial sodium channel Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
  • Epitopes Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
  • Equol Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis [Volume 25, Issue 10, 2022, Pages 1228-1233]
  • ER stress Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
  • ER stress Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
  • Escherichia coli O157:H7 Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
  • Escitalopram Therapeutic effects of exercise-accompanied escitalopram on synaptic potency and long-term plasticity in the hippocampal CA1 area in rats under chronic restraint stress [Volume 25, Issue 12, 2022, Pages 1460-1467]
  • Esophageal squamous cell carcinoma MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
  • Ethanol Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
  • Eucommia ulmoides leaves Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
  • Eudragit Preparation of stable enteric folic acid-loaded microfiber using the electrospinning method [Volume 25, Issue 3, 2022, Pages 405-413]
  • Evolutionary analysis In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
  • Excitotoxicity Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
  • Exercise Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
  • Exercise Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
  • Exercise Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
  • Exercise Therapeutic effects of exercise-accompanied escitalopram on synaptic potency and long-term plasticity in the hippocampal CA1 area in rats under chronic restraint stress [Volume 25, Issue 12, 2022, Pages 1460-1467]
  • Exosome Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
  • Exosome Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
  • Exosomes A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
  • Exotoxin A Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]
  • Experimental autoimmune - encephalomyelitis Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
  • Expression Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
  • Extinction Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
  • Extracellular matrix Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
  • Extracellular signal-regulated kinases Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]

F

  • FABP4 Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
  • Farnesoid-X-receptor Biliary cirrhosis-induced cardiac abnormality in rats: Interaction between Farnesoid-X-activated receptors and the cardiac uncoupling proteins 2 and 3 [Volume 25, Issue 1, 2022, Pages 126-133]
  • Fas Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
  • Fas ligand protein Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
  • Fas receptor Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
  • Fatty liver Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
  • Fecal carrier High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
  • Fertility preservation Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
  • Fetuin-A Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
  • Fibroblast Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
  • Ficus carica Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
  • Filgrastim Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
  • Flavonoids Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
  • FOXN3 MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
  • Free radicals Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
  • Fulvic acid Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]

G

  • GABA receptor Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
  • Gallbladder dysmotility Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
  • Garlic Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
  • Gastric cancer Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
  • Gastric ulcer Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
  • Gastroparesis Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
  • Gata-3 Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice [Volume 25, Issue 10, 2022, Pages 1267-1274]
  • Gemcitabine Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
  • Gene delivery Recent advances in development of nano-carriers for immunogene therapy in various complex disorders [Volume 25, Issue 2, 2022, Pages 134-147]
  • Gene expression Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
  • Gene expression Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
  • Genes In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
  • Genetic polymorphism Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
  • Genome-wide mutations In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
  • Genotypic Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
  • Gentamicin Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [Volume 25, Issue 1, 2022, Pages 121-125]
  • Giardia lamblia Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
  • Ginsenoside Rh2 In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
  • Glomerulonephritis Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
  • Glutamate Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
  • Glutamate Effect of MK-801, an antagonist of NMDA receptor in the pedunculopontine tegmental nucleus, on cardiovascular parameters in normotensive and hydralazine hypotensive rats [Volume 25, Issue 5, 2022, Pages 569-576]
  • Glutathione Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
  • Glutathione Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
  • Glycerol Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]
  • Glycolysis MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
  • Glycyrrhizin Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
  • Glycyrrihza glabra Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
  • Glyoxalase 1 Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
  • Gold Nanoparticle Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
  • Gonadotropin-Releasing Hormone Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
  • Granulocyte differentiation Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
  • Granulocyte-macrophage- colony-stimulating factor Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
  • Graphene In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
  • Graphene nanosheet Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
  • Growth MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
  • Guanosine Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]
  • Guinea pigs Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
  • Gut microbiota Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]

H

  • H9C2 cells Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
  • HBs antigen PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
  • HBx Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
  • HBZ TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
  • Heart Arrest Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
  • Heat- shock proteins Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
  • Hemiparkinsonism The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
  • Hemodynamic parameters Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
  • Hemolysins Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
  • Hepatic regeneration Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
  • Hepatocellular Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
  • Hepatocellular Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
  • Hidden hearing loss Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
  • High-fat and high-fructose diet Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
  • High-fat diet Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]
  • High glucose Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
  • HIIT exercise The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
  • Hippocampal CA1 Region Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
  • Hippocampus The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
  • Hippocampus Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome [Volume 25, Issue 11, 2022, Pages 1308-1316]
  • Hippocampus Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
  • Histology Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
  • Histomorphology ovary Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
  • Histopathological findings Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
  • HIV-1 Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
  • HSCs/LX2 Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
  • HSD17B3 Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
  • HTLV TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
  • Humic acid Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
  • HUVECs Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [Volume 25, Issue 4, 2022, Pages 506-513]
  • Hyperbaric oxygen therapy Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]
  • Hypercholesterolemia Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
  • Hyperforin Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
  • Hypericaceae Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
  • Hypericin Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
  • Hypericum perforatum Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
  • Hyperlipidemia A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
  • Hypertension A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
  • Hypertension Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
  • Hypertension The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]
  • Hypertension Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
  • Hypertension Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
  • Hypertrophy LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
  • Hyperuricemia Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
  • Hypotension Effect of MK-801, an antagonist of NMDA receptor in the pedunculopontine tegmental nucleus, on cardiovascular parameters in normotensive and hydralazine hypotensive rats [Volume 25, Issue 5, 2022, Pages 569-576]
  • Hypothalamus Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
  • Hypothalamus Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance [Volume 25, Issue 9, 2022, Pages 1117-1122]
  • Hypothyroidism Investigation of the endometrial receptivity status in experimental hypothyroid-induced female rats [Volume 25, Issue 9, 2022, Pages 1077-1083]

I

  • Iba1 Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
  • ICU Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
  • IL-10 Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
  • IL-6 Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
  • Immune responses Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
  • Immunity Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
  • Immunization passive TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
  • Immunogene therapy Recent advances in development of nano-carriers for immunogene therapy in various complex disorders [Volume 25, Issue 2, 2022, Pages 134-147]
  • Immunologic factors Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
  • Immunotherapy In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
  • Immunotherapy Recent advances in development of nano-carriers for immunogene therapy in various complex disorders [Volume 25, Issue 2, 2022, Pages 134-147]
  • Immunotoxin In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
  • Inactivated SARS-CoV-2 - virus Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
  • Inactivated vaccine Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
  • Indigenous Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
  • Infection Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
  • Infection Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]
  • Infection control measures Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [Volume 25, Issue 2, 2022, Pages 239-244]
  • Infertility Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
  • Infertility Investigation of the endometrial receptivity status in experimental hypothyroid-induced female rats [Volume 25, Issue 9, 2022, Pages 1077-1083]
  • Inflammation Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
  • Inflammation Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
  • Inflammation Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
  • Inflammation Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
  • Inflammation Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]
  • Inflammation 6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation [Volume 25, Issue 5, 2022, Pages 629-634]
  • Inflammation Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
  • Inflammation Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]
  • Inflammation Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
  • Inflammation Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
  • Inflammation Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
  • Inflammation Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
  • Inflammation Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
  • Inflammation Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
  • Inflammation Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
  • Inflammation Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [Volume 25, Issue 8, 2022, Pages 1021-1027]
  • Inflammation Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
  • Inflammation Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
  • Inflammation Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
  • Inflammatory diseases An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
  • INOS Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
  • In situ forming hydrogel- gelling Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
  • Insular cortex Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
  • Insulin Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
  • Insulin Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
  • Insulin Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome [Volume 25, Issue 11, 2022, Pages 1308-1316]
  • Insulin-Like Growth Factor I Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
  • Insulin receptor substrate - proteins Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
  • Insulin-secreting cells Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
  • Insulin secretion Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction [Volume 25, Issue 4, 2022, Pages 483-488]
  • Intensive Care Units Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [Volume 25, Issue 2, 2022, Pages 239-244]
  • Interferon-gamma Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice [Volume 25, Issue 7, 2022, Pages 890-896]
  • Interstitial cajal-like cells Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
  • Interstitial cells of Cajal Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
  • Ion channel remodeling Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
  • Iran Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
  • Iron oxide Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
  • Ischemia Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
  • Ischemia Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
  • Ischemia JNK and p38 gene and protein expression during liver ischemia-reperfusion in a rat model treated with silibinin [Volume 25, Issue 11, 2022, Pages 1373-1381]
  • Ischemia/Reperfusion Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
  • Ischemia/Reperfusion injury Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
  • Isoproterenol TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]

J

  • Jak2 / Stat3 Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
  • JNK JNK and p38 gene and protein expression during liver ischemia-reperfusion in a rat model treated with silibinin [Volume 25, Issue 11, 2022, Pages 1373-1381]

K

  • K-ATPases Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
  • Kidney disorder Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
  • Kidney Injury Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
  • Kidney ischemia reperfusion Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
  • Klotho Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]

L

  • Lactobacilli Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
  • Lactoferrin Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
  • LasR Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
  • Lavender oil Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
  • L-carnitine Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
  • LC-MS LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
  • L-deprenyl Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
  • Leptin Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
  • Letrozole Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
  • Levothyroxine sodium Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
  • Lipid droplet MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
  • Liposome Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
  • Liposome Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
  • Liposomes Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice [Volume 25, Issue 7, 2022, Pages 890-896]
  • Liver Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
  • Liver Cirrhosis Biliary cirrhosis-induced cardiac abnormality in rats: Interaction between Farnesoid-X-activated receptors and the cardiac uncoupling proteins 2 and 3 [Volume 25, Issue 1, 2022, Pages 126-133]
  • Liver failure Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
  • Liver fibrosis Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
  • Local EEG The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
  • Long-lived IgG response PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
  • Long noncoding Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
  • Long Noncoding RNA Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
  • Long-term potentiation Therapeutic effects of exercise-accompanied escitalopram on synaptic potency and long-term plasticity in the hippocampal CA1 area in rats under chronic restraint stress [Volume 25, Issue 12, 2022, Pages 1460-1467]
  • Low-density lipoprotein - receptors Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
  • LOXL2 protein LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
  • LSD1 inhibitor Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]

M

  • Macrophage Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
  • Macrophage Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
  • Macrophages Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]
  • MAGI2-AS3 MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
  • Magnetic vanoparticles A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
  • Malaysia Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
  • Malondialdehyde Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
  • Mangostin Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
  • MAPK TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
  • MAP kinase signaling - system Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [Volume 25, Issue 8, 2022, Pages 1021-1027]
  • MAPK/NF-κB signaling Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
  • MARCH-1 Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
  • Mast cell 6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation [Volume 25, Issue 5, 2022, Pages 629-634]
  • MBL Phenotypic and genotypic investigation of metallo-β-lactamases in Pseudomonas aeruginosa clinical isolates in Bushehr, Iran [Volume 25, Issue 10, 2022, Pages 1196-1200]
  • MDMA Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
  • Mechanical Strength Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
  • Medical equipment Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
  • Medicinal Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
  • Melanoma Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
  • Melatonin Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
  • Memory Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
  • Mesenchymal stem cell Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
  • Mesenchymal stem cell Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
  • Mesenchymal stem cells Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
  • Mesenchymal stem cells A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
  • Mesenchymal stem cells Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
  • Mesenchymal stem cells Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
  • Mesoporous structure Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
  • Metabolic zone MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
  • Metabolite profiling LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
  • Metallo-β-lactamase Phenotypic and genotypic investigation of metallo-β-lactamases in Pseudomonas aeruginosa clinical isolates in Bushehr, Iran [Volume 25, Issue 10, 2022, Pages 1196-1200]
  • Metformin Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [Volume 25, Issue 4, 2022, Pages 506-513]
  • Metformin Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
  • Methicillin-resistant - Staphylococcus aureus Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
  • Methicillin-resistant - Staphylococcus aureus High prevalence and expression of antiseptic resistance genes among infectious t037/ST239 methicillin-resistant Staphylococcus aureus (MRSA) strains in North Khorasan Province, Iran [Volume 25, Issue 6, 2022, Pages 775-780]
  • Methotrexate Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
  • Methotrexate In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
  • Methylglyoxal Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
  • Methylglyoxal Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
  • MF59 PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
  • Mice Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
  • Mice Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
  • Microarray Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
  • Microbial sensitivity tests Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
  • Microfiber Preparation of stable enteric folic acid-loaded microfiber using the electrospinning method [Volume 25, Issue 3, 2022, Pages 405-413]
  • Microglia Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
  • MicroRNA MicroRNA-96: A therapeutic and diagnostic tumor marker [Volume 25, Issue 1, 2022, Pages 3-13]
  • MicroRNA Wound dressings incorporating microRNAs: Innovative therapy for diabetic wound treatment [Volume 25, Issue 9, 2022, Pages 1042-1044]
  • Midazolam Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]
  • Migration Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]
  • Milk Thistle A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
  • MiR-574-5p MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
  • Mitochondrial biogenesis Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
  • Mitochondrial dynamics MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
  • Mitochondrial dysfunction Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
  • Mitochondrial functions An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
  • Mitochondrial uncoupling proteins Biliary cirrhosis-induced cardiac abnormality in rats: Interaction between Farnesoid-X-activated receptors and the cardiac uncoupling proteins 2 and 3 [Volume 25, Issue 1, 2022, Pages 126-133]
  • Mitophagy MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
  • Molecular docking Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
  • Molecular docking Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
  • Monoclonal antibody Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
  • Monoclonal antibody Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
  • Monosodium glutamate Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
  • Morphine Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
  • Mst1 Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
  • Multiple sclerosis Neuroinflammation Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
  • MyD88 TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
  • Myocardial infarction Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
  • Myocardial schemia Oxidative stress Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]

N

  • Na Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
  • N-acetylcysteine Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
  • NAD⁺ Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
  • NADPH oxidase Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
  • NAFLD Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance [Volume 25, Issue 9, 2022, Pages 1117-1122]
  • Naloxone Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
  • Nanobody Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
  • Nano-carriers Recent advances in development of nano-carriers for immunogene therapy in various complex disorders [Volume 25, Issue 2, 2022, Pages 134-147]
  • Nanoemulgel formulation Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
  • Nano-hybrid Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
  • Nanoparticle Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
  • Nanovaccine A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
  • Nanovaccine Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
  • Nasal and parenteral immunization A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
  • Nasopharyngeal carcinoma Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
  • Natural toxin Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article [Volume 25, Issue 12, 2022, Pages 1402-1415]
  • Necrotizing Enterocolitis Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
  • Neobavaisoflavone Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [Volume 25, Issue 8, 2022, Pages 1021-1027]
  • Neoplasms A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
  • Nephropathy Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
  • Nephroprotective Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
  • Nephrotoxicity Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
  • Nephrotoxicity Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
  • Nettle A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
  • Network pharmacology Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
  • Neural tissue engineering Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
  • Neurogenesis Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome [Volume 25, Issue 11, 2022, Pages 1308-1316]
  • Neuroinflammation Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
  • Neuroinflammation Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
  • Neuroinflammation Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
  • Neuroinflammatory - diseases Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
  • Neuronal plasticity Therapeutic effects of exercise-accompanied escitalopram on synaptic potency and long-term plasticity in the hippocampal CA1 area in rats under chronic restraint stress [Volume 25, Issue 12, 2022, Pages 1460-1467]
  • Neuroprotection Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
  • Neurotoxicity Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
  • Neurotoxicity Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
  • Neutralizing antibodies Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
  • Neutrophils Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
  • NF-E2-related factor 2 Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
  • NF-kappa B Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [Volume 25, Issue 8, 2022, Pages 1021-1027]
  • NF-kappa B TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
  • NF-kB Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
  • NF-kB Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
  • NF-ƙB C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
  • NF-ƙB Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
  • NF-κB Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
  • Nicotine Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
  • Nilotinib Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
  • Nitric oxide Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
  • Nitric oxide Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
  • NLR Family Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
  • NLRP3 Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
  • NLRP3 inflammasome Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
  • NLRP3 inflammasome Nuclear factor - kappa B Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
  • NMDA receptor Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
  • NMDA receptor Effect of MK-801, an antagonist of NMDA receptor in the pedunculopontine tegmental nucleus, on cardiovascular parameters in normotensive and hydralazine hypotensive rats [Volume 25, Issue 5, 2022, Pages 569-576]
  • Noise-induced hearing loss Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
  • Nosocomial infection High prevalence and expression of antiseptic resistance genes among infectious t037/ST239 methicillin-resistant Staphylococcus aureus (MRSA) strains in North Khorasan Province, Iran [Volume 25, Issue 6, 2022, Pages 775-780]
  • Nrf2 Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
  • Nrf2 Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
  • Nrf2 Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
  • Nrf2 Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
  • Nrf2 Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
  • NSCLC Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]

O

  • Obesity Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
  • Obesity The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]
  • Obesity Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
  • Obesity Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
  • Obesity Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
  • Occludin Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
  • OHSS Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
  • Olanzapine Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
  • Olea europaea Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
  • Omega-3 Fatty Acids Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
  • Oncogene Protein v-akt MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
  • Oral colonization Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [Volume 25, Issue 2, 2022, Pages 239-244]
  • Oral vaccine Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
  • Osteoarthritis Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis [Volume 25, Issue 10, 2022, Pages 1228-1233]
  • Osteogenesis Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells [Volume 25, Issue 11, 2022, Pages 1364-1372]
  • Osteosarcoma 1,3,5-triazines inhibit osteosarcoma and avert lung metastasis in a patient-derived orthotopic xenograft mouse model with favorable pharmacokinetics [Volume 25, Issue 3, 2022, Pages 295-301]
  • Ototoxicity Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [Volume 25, Issue 1, 2022, Pages 121-125]
  • Ovarian Follicle Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
  • Ovariectomised rats Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis [Volume 25, Issue 10, 2022, Pages 1228-1233]
  • Ovariectomy Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
  • Ovary Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
  • Oxidative Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
  • Oxidative Enzymes Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
  • Oxidative stress Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
  • Oxidative stress Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
  • Oxidative stress Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
  • Oxidative stress Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
  • Oxidative stress The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
  • Oxidative stress Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
  • Oxidative stress Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
  • Oxidative stress Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
  • Oxidative stress Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
  • Oxidative stress Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
  • Oxidative stress Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
  • Oxidative stress Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
  • Oxidative stress Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
  • Oxidative stress Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
  • Oxidative stress Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
  • Oxidative stress Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
  • Oxidative stress Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
  • Oxidative stress MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
  • Oxidative stress Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
  • Ozone therapy Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]

P

  • P53 Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
  • Paclitaxel Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
  • Pancreatic duodenal homeobox protein-1 Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction [Volume 25, Issue 4, 2022, Pages 483-488]
  • Paraquat Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
  • Parkinson’s disease Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
  • Particulate Matter Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
  • Patient-derived xenograft Combination of T-DM1 and platinum-based chemotherapy in patient-derived xenograft models of muscle-invasive bladder cancer [Volume 25, Issue 7, 2022, Pages 816-821]
  • Pattern recognition receptors Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
  • PBP2a Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
  • Pedunculopontine tegmental nucleus Effect of MK-801, an antagonist of NMDA receptor in the pedunculopontine tegmental nucleus, on cardiovascular parameters in normotensive and hydralazine hypotensive rats [Volume 25, Issue 5, 2022, Pages 569-576]
  • Penile erection Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
  • Pergularia tomentosa LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
  • Periodontitis Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway [Volume 25, Issue 5, 2022, Pages 635-642]
  • PFGE High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
  • Phage display library Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
  • Pharmaceutical preparations A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
  • Pharmacokinetics Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]
  • Phenotypic Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
  • Photochemical - internalization Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
  • Photodynamic Therapy Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
  • Physioxia Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
  • Phytochemicals LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
  • Phytotherapy Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
  • PI3K 1,3,5-triazines inhibit osteosarcoma and avert lung metastasis in a patient-derived orthotopic xenograft mouse model with favorable pharmacokinetics [Volume 25, Issue 3, 2022, Pages 295-301]
  • PI3K/Akt Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway [Volume 25, Issue 5, 2022, Pages 635-642]
  • PI3K/Akt/mTOR Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance [Volume 25, Issue 9, 2022, Pages 1117-1122]
  • Pichia pastoris TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
  • Plant extracts A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
  • Plasmids Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
  • Platelet activation Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]
  • PLGA Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
  • PNC27 peptide Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
  • Polarization Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
  • Polycystic ovary syndrome Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
  • Polycystic ovary syndrome Prenatal Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
  • Polymer In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
  • Polyurethane foam Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
  • Polyvinyl alcohol Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
  • Portal Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
  • Portulaca oleracea Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
  • Post-insertion Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
  • Postsynaptic density protein-95 Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
  • Post-traumatic stress disorder Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
  • PPARγ Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
  • PPARγ Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
  • PPD PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
  • Prefrontal cortex Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
  • Prepulse inhibition Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
  • Prognosis MicroRNA-96: A therapeutic and diagnostic tumor marker [Volume 25, Issue 1, 2022, Pages 3-13]
  • Programmed cell death - ligand-1 Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
  • Pro-inflammatory cytokines Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
  • Proliferation Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
  • Propylthiouracil Investigation of the endometrial receptivity status in experimental hypothyroid-induced female rats [Volume 25, Issue 9, 2022, Pages 1077-1083]
  • Prosopis africana Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
  • Protective Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article [Volume 25, Issue 12, 2022, Pages 1402-1415]
  • Protein Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
  • Protoporphyrin-IX Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
  • Pseudomonas aeruginosa Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
  • Pseudomonas aeruginosa Phenotypic and genotypic investigation of metallo-β-lactamases in Pseudomonas aeruginosa clinical isolates in Bushehr, Iran [Volume 25, Issue 10, 2022, Pages 1196-1200]
  • Pseudomonas aeruginosa Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]
  • Pulmonary arterial - hypertension Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
  • Pulmonary edema Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
  • Purslane Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
  • Putrescine Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
  • Pyrazolone New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
  • Pyrin domain containing 3 Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
  • Pyroptosis Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
  • Pyroptosis Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]

Q

  • Q10 Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
  • Quercus Safety assessment of the Quercus brantii gall hydroalcoholic extract: Single and repeated oral dose toxicity studies [Volume 25, Issue 11, 2022, Pages 1389-1395]
  • Quercus brantii gall Safety assessment of the Quercus brantii gall hydroalcoholic extract: Single and repeated oral dose toxicity studies [Volume 25, Issue 11, 2022, Pages 1389-1395]
  • Quorum sensing Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]

R

  • Radiosensitivity Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
  • Radiotherapy Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
  • Ramelteon Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
  • Ranolazine Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]
  • Rat Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
  • Rat Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
  • Rat Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
  • Rat The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
  • Rat Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
  • Rat Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
  • Rat Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
  • Rat Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
  • Rat Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
  • Rat Safety assessment of the Quercus brantii gall hydroalcoholic extract: Single and repeated oral dose toxicity studies [Volume 25, Issue 11, 2022, Pages 1389-1395]
  • Rats Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
  • RBD Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
  • Reactive Oxygen Species Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
  • Recombinant fusion peptide A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
  • Recombinant Ib-AMP4 Ib-AMP4 antimicrobial peptide as a treatment for skin and systematic infection of methicillin-resistant Staphylococcus aureus (MRSA) [Volume 25, Issue 2, 2022, Pages 232-238]
  • Recombinant protein Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
  • Recombinant protein Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
  • Recombinant proteins TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
  • Recombinant proteins Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
  • REM Sleep Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
  • REM sleep deprivation Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]
  • Renal fibrosis Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
  • Renal tubular epithelial cell Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
  • Repeated dose toxicity Safety assessment of the Quercus brantii gall hydroalcoholic extract: Single and repeated oral dose toxicity studies [Volume 25, Issue 11, 2022, Pages 1389-1395]
  • Reperfusion Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
  • Reperfusion Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
  • Reperfusion JNK and p38 gene and protein expression during liver ischemia-reperfusion in a rat model treated with silibinin [Volume 25, Issue 11, 2022, Pages 1373-1381]
  • Replication Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]
  • Resveratrol The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
  • RFamide-related peptide-3 Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
  • RNA Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
  • RNA Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
  • RNAi-based therapeutics Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
  • RNA-Seq Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
  • ROS Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
  • ROS Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
  • ROS Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
  • Rotavirus Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]

S

  • Saffron Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
  • Saffron Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
  • Saffron Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
  • Safranal Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
  • Safranal Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
  • Sanguinarine Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]
  • Saroglitazar Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
  • SARS-CoV-2 Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
  • SARS-CoV-2 In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
  • Scaffold A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
  • Sciatic nerve Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
  • Secretory IgA Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
  • Selegiline Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
  • Self-assembled nanomicelles A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
  • Sema3A Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]
  • Sepsis Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]
  • Sepsis Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
  • Sepsis-associated-encephalopathy Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]
  • Serotonin Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]
  • Serum Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
  • Shiga toxin Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
  • Signaling pathways Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
  • Silibinin JNK and p38 gene and protein expression during liver ischemia-reperfusion in a rat model treated with silibinin [Volume 25, Issue 11, 2022, Pages 1373-1381]
  • Silybum marianum L A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
  • Silymarin A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
  • Sinapic acid Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
  • Single-chain variable - fragment Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
  • Single-chain variable-fragment Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
  • Single-domain antibodies In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
  • Single domain antibody Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
  • Sirolimus Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
  • Sirtuin 1 Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
  • Sirtuins The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
  • Sitagliptin Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]
  • Skin and systematic infection Ib-AMP4 antimicrobial peptide as a treatment for skin and systematic infection of methicillin-resistant Staphylococcus aureus (MRSA) [Volume 25, Issue 2, 2022, Pages 232-238]
  • SKP1 inhibitor 6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation [Volume 25, Issue 5, 2022, Pages 629-634]
  • SLC29A1 protein Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
  • Sleep deprivation Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
  • Sleep deprivation Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
  • Smart hydrogels Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
  • Smooth Muscle Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
  • Social behavior Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
  • Sodium butyrate Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
  • Soluble Fzd7 Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
  • Somatosensory cortex TRPV1 Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
  • Spatial Memory Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
  • Spermatogenesis Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
  • Spermidine/Spermine-N(1) Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
  • Spider venoms Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]
  • Spinosin Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
  • SPIONs Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
  • Spleen Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
  • Staphylococcal infections Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
  • Staphylococcus aureus Ib-AMP4 antimicrobial peptide as a treatment for skin and systematic infection of methicillin-resistant Staphylococcus aureus (MRSA) [Volume 25, Issue 2, 2022, Pages 232-238]
  • Staphylococcus aureus Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
  • StaR Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
  • Startle reflex Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
  • STAT3 Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
  • Stem cell factor Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
  • Steroids Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
  • St. John’s wort Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
  • Stomach neoplasms Transcriptome Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
  • Stride-length The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
  • Subchondral bone Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis [Volume 25, Issue 10, 2022, Pages 1228-1233]
  • Sumac Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]
  • Survivin Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
  • Synapsin I Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
  • Synaptic plasticity Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
  • Synaptophysin Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
  • Systemic inflammatory-response Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]

T

  • Tanshinone Ⅰ Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
  • Tapentadol Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
  • Targeted cancer diagnostic Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
  • Targeted therapy Combination of T-DM1 and platinum-based chemotherapy in patient-derived xenograft models of muscle-invasive bladder cancer [Volume 25, Issue 7, 2022, Pages 816-821]
  • Tax TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
  • T-box transcription factor Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice [Volume 25, Issue 10, 2022, Pages 1267-1274]
  • T-DM1 Combination of T-DM1 and platinum-based chemotherapy in patient-derived xenograft models of muscle-invasive bladder cancer [Volume 25, Issue 7, 2022, Pages 816-821]
  • Temperature-responsive- systems Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
  • Testes Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
  • Testis Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
  • Tetani Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
  • Tetratricopeptide repeat domain 9A (TTC9A) Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
  • TGF-beta Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
  • TGF-β Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
  • TGF β/Smad3C Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
  • Theaflavin Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
  • Therapy Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
  • Thiazole compound Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
  • Thymoquinone Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
  • Tight junction proteins Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
  • Time restriction Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
  • Tinnitus Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
  • Tissue engineering A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
  • Tissue regeneration Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
  • TMAO Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
  • TNBC Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
  • TNF-α Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
  • Toll-Like Receptor Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]
  • Toll-Like Receptor TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
  • Toll-like receptor 4 Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]
  • Toxicity studies Safety assessment of the Quercus brantii gall hydroalcoholic extract: Single and repeated oral dose toxicity studies [Volume 25, Issue 11, 2022, Pages 1389-1395]
  • Toxin Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
  • Tramadol Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
  • Transient outward - potassium current Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
  • Treatment Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
  • Triblock copolymer Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
  • TRPM7 Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
  • TRPV1 Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway [Volume 25, Issue 5, 2022, Pages 635-642]
  • Tuberculosis A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
  • Tubular necrosis Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
  • Tumor In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
  • Tumor In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
  • Tunicamycin Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
  • Type 2 diabetes mellitus β-cell Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction [Volume 25, Issue 4, 2022, Pages 483-488]
  • Tyrosinase Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
  • Tyrosine kinase inhibitor Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]

U

  • Ulinastatin Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
  • Ultrastructure features Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
  • Urinary bladder neoplasms Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
  • Urinastatin Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
  • Urtica dioica A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
  • Uterine Cervical Neoplasms Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
  • Uterine ischemia Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]

V

  • Vaccine Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
  • Vaccine Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
  • Vaccine formulation Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
  • Vaccines Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
  • Vascular endothelial - Growth factor receptor-2 In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
  • Vascular endothelial growth - factor (VEGF) In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
  • Vasopressins Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
  • Venous thrombosis Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]
  • Ventricular hypertrophy Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
  • Verocytotoxin (VT)-producing Escherichia coli (VTEC) Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
  • Viability Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
  • Vitamin B12 Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
  • Vitamin D3 Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
  • Volume of distribution Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]

W

  • Wasp venoms Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
  • Weight gain Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
  • Western blot New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
  • Whartons’ jelly Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
  • Whiteleg shrimp Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
  • Whole exome sequencing Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
  • Wound healing Wound dressings incorporating microRNAs: Innovative therapy for diabetic wound treatment [Volume 25, Issue 9, 2022, Pages 1042-1044]
  • Wound therapy Wound dressings incorporating microRNAs: Innovative therapy for diabetic wound treatment [Volume 25, Issue 9, 2022, Pages 1042-1044]
  • WV Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]

Z

  • ZBTB7A Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
  • Zingiber The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]
  • Zizyphus Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
  • Zymosan Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]