Iranian Journal of Basic Medical Sciences

Keyword Index

A

Acinetobacter baumannii Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [Volume 25, Issue 2, 2022, Pages 239-244]
Acinetobacter baumannii Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
Acrylamide Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
Actins Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
Acupuncture points injection Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
Acute kidney injury Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
Acute kidney injury Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]
Acute kidney injury Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
Acute kidney injury Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
Acute lung injury Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
Acute lung injury Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
Acute lung injury Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
Addiction Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
Adipogenesis Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
Adipose-derived mesenchymal stem cells Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
Adjuvant PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
Aerobic training Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
Aggression Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
Aging The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
Aging Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
AKI Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
ALL MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
Allergy 6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation [Volume 25, Issue 5, 2022, Pages 629-634]
Alum Adjuvant Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
Alzheimer Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
Alzheimer’s disease Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
Ambroxol Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
Aminoglycoside Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [Volume 25, Issue 1, 2022, Pages 121-125]
Amnesia Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
AMPK Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
Amygdala Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
Angiogenesis In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
Angiogenesis Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [Volume 25, Issue 4, 2022, Pages 506-513]
Angiogenesis Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
Angiogenesis inhibitors In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
Angiotensin II LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
Angiotensin II Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
Angiotensin receptor Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
Anti-apoptotic Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
Anti-apoptotic Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]
Antibacterial agents Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
Antibiotic resistance Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
Antibiotic resistance High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
Anticonvulsant New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
Anti-inflammatory Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]
Anti-inflammatory Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
Anti-inflammatory Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
Anti-inflammatory New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
Antimicrobial activity Ib-AMP4 antimicrobial peptide as a treatment for skin and systematic infection of methicillin-resistant Staphylococcus aureus (MRSA) [Volume 25, Issue 2, 2022, Pages 232-238]
Antineoplastic agents Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
Antineoplastic agents A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
Antineoplastic protocols Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
Anti-oxidant Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [Volume 25, Issue 1, 2022, Pages 121-125]
Anti-oxidant Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
Anti-oxidant Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article [Volume 25, Issue 12, 2022, Pages 1402-1415]
Anti-oxidant Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
Anti-oxidant Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
Anti-oxidant New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
Anti-Oxidants Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
Anti-Oxidants Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
Anti-Oxidants Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
Anti-Oxidants A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
Anti-Oxidants Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
Anti-Oxidants MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
Antioxidant therapy Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]
Anti-PCSK9 antibody Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]
Antiproliferation Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]
Anti-tumor activity Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
Anti-virulent strategy Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
Anxiety Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
Apoptosis MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
Apoptosis Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
Apoptosis Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
Apoptosis Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
Apoptosis Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
Apoptosis Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
Apoptosis Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
Apoptosis Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
Apoptosis 1,3,5-triazines inhibit osteosarcoma and avert lung metastasis in a patient-derived orthotopic xenograft mouse model with favorable pharmacokinetics [Volume 25, Issue 3, 2022, Pages 295-301]
Apoptosis Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
Apoptosis Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
Apoptosis Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
Apoptosis Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
Apoptosis Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
Apoptosis Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
Apoptosis Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
Apoptosis Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
Apoptosis Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
Apoptosis Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
Apoptosis TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
Argatroban Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]
Arginine In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
Artificial organs Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
Asia In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
Astaxanthin Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
Asthma C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
Asthma Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice [Volume 25, Issue 10, 2022, Pages 1267-1274]
Astragaloside IV Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
Astrocyte Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
Astrogliosis Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
Atherosclerosis Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
Atherosclerosis Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
ATLL TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
Atractylodes Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
Atrial fibrillation LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
Autolysin Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
Autophagy Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
Autophagy Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
Autophagy Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
Autophagy Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
Autophagy Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
Autophagy Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells [Volume 25, Issue 11, 2022, Pages 1364-1372]

B

Baicalein An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
Baicalin An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
Bax Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
Bax protein Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice [Volume 25, Issue 7, 2022, Pages 890-896]
Bcl-2 Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
Bcl-2 Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
Bead Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
Behavioral tests Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
Behavior tests Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome [Volume 25, Issue 11, 2022, Pages 1308-1316]
Benzalkonium chloride,Benzethonium chloride High prevalence and expression of antiseptic resistance genes among infectious t037/ST239 methicillin-resistant Staphylococcus aureus (MRSA) strains in North Khorasan Province, Iran [Volume 25, Issue 6, 2022, Pages 775-780]
Berberine Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
Betulinic acid The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
Bifidobacterium Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
Bioactive peptides Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
Biodistribution Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
Biofilm Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]
Bioinformatics Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells [Volume 25, Issue 11, 2022, Pages 1364-1372]
Biomarkers Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
Biomarkers Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
Biomedical application Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
Bladder cancer Combination of T-DM1 and platinum-based chemotherapy in patient-derived xenograft models of muscle-invasive bladder cancer [Volume 25, Issue 7, 2022, Pages 816-821]
Blood Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
Blood-brain barrier Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
Blood coagulation factors Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]
BM C-kit+ HSCs Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
BMP2 Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]
Boldenone Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
Bone marrow mesenchymal stem cells Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells [Volume 25, Issue 11, 2022, Pages 1364-1372]
Boraginaceae Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
Botulinum Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
B-PEI Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
Brain barrier dysfunction Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
Brain damage Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
Brain-derived neurotrophic factor Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
Brain drug delivery Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
Brain Injuries Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
Brain Injuries Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
Brain ischemia Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
Brain ischemia Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
Breast Cancer Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
Breast Cancer Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
Breast Cancer In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]

C

Cabergolin Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
Caffeic acid Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
Calcium dobesilate Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
Calcium-sensing receptor Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]
Calorie restriction Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
Cancer MicroRNA-96: A therapeutic and diagnostic tumor marker [Volume 25, Issue 1, 2022, Pages 3-13]
Cancer An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
Cancer Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
Cancer Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [Volume 25, Issue 4, 2022, Pages 506-513]
Cannabinoid receptor Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
Cannabinoid receptors Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
Carbapenemase High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
Carbon tetrachloride Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
Carcinoma Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
Carcinoma Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
Cardenolides LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
Cardiac fibrosis Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
Cardiomyopathy Biliary cirrhosis-induced cardiac abnormality in rats: Interaction between Farnesoid-X-activated receptors and the cardiac uncoupling proteins 2 and 3 [Volume 25, Issue 1, 2022, Pages 126-133]
Cardiopulmonary - Resuscitation Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
Carvedilol Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
Carveol Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
Caspase-3 Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]
Catalase Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
Catalase The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
CCR8 Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
CD4+/CD8+ C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
Celastrol Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
Cell-based therapy Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
Cell cycle checkpoints Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
Cell death Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
Cell Proliferation MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
Cell therapy Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
Central nucleus of amygdala Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
Cerebral infarction Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
Cerebral toxicity Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
Cervical Cancer Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
Cervical Intraepithelial - neoplasia Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
Checkpoint inhibitors Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
Chemical toxic agent Ellagic acid Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article [Volume 25, Issue 12, 2022, Pages 1402-1415]
Chemotherapeutic resistance Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
Chitosan Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
Chlorhexidine gluconate High prevalence and expression of antiseptic resistance genes among infectious t037/ST239 methicillin-resistant Staphylococcus aureus (MRSA) strains in North Khorasan Province, Iran [Volume 25, Issue 6, 2022, Pages 775-780]
Chromone derivatives Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
Chronic inflammatory pain Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
Cigarette Smoking Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
Cilostazol Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
Circular RNA Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
Cisplatin Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
Cisplatin Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
Cisplatin Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
Citicoline Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
C-kit cells C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
Claudin-5 Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
Clearance Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]
Clinical trial Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
Clinical Trials Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
Cloning Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
Clostridium Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
CML Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
Cobalt Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
Cochlear synaptopathy Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
Coenzyme Q10 Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
Cognitive impairment Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]
Colistin Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
Collagen Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
Colon cancer Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
Colorectal cancer Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice [Volume 25, Issue 7, 2022, Pages 890-896]
Comfrey Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
Common bile duct ligation Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
Competing- endogenous - RNA Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
Conditioned medium Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
Conjugated linoleic acid Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
Constipation Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]
Contusion Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
Coronary Artery Disease Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
Coronary Stent Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
Coronary vessels Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
Corpus striatum Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
COVID-19 Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
COVID-19 In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
Creatine Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
Crocetin Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
Crocin Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
Crocin Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
Crocin Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
Crocin Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
Crocin Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
Crocin Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
Crocus Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
Crocus sativus Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
CTDSP1 protein MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
Cuprizone Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
Curcumol Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
Cyclin D Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
Cyclooxygenases Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]
CYP2C19 variants Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
Cysteine-rich transmembrane Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
Cytochrome P450 Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
Cytokine Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
Cytokine Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
Cytokines Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway [Volume 25, Issue 5, 2022, Pages 635-642]
Cytotoxicity effect Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]

D

Daidzein Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
Dapsone Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
Decoy receptor Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
Deep brain stimulation Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
Degradation Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
D-galactose Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
Diabesity Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
Diabetes Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
Diabetes Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
Diabetes A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
Diabetes The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]
Diabetes Mellitus Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]
Diabetes Mellitus Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
Diabetes Mellitus Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
Diabetes Mellitus LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
Diabetic foot Wound dressings incorporating microRNAs: Innovative therapy for diabetic wound treatment [Volume 25, Issue 9, 2022, Pages 1042-1044]
Diabetic nephropathy Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
Diabetic nephropathy Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
Diabetic nephropathy Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
Diagnosis MicroRNA-96: A therapeutic and diagnostic tumor marker [Volume 25, Issue 1, 2022, Pages 3-13]
Diarrhea Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]
Diclofenac Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
Diet Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
Diethylnitrosamine Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
Differentiation C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
Difficile Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
Diffusion Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
Dioscin Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]
Disease Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
Distant organ effect Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
DNA damage Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
Dopamine D2 receptor - antagonist Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
Dorsal root ganglion Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
Double-Strand Break Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
Dressings Wound dressings incorporating microRNAs: Innovative therapy for diabetic wound treatment [Volume 25, Issue 9, 2022, Pages 1042-1044]
Drug Delivery Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
Drug Delivery system Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
Drug metabolism Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
Drug-resistance Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
Dulaglutide Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
Dyslipidemia The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]

E

EAE model Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
Electrophysiological factors Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
Electrospinning Preparation of stable enteric folic acid-loaded microfiber using the electrospinning method [Volume 25, Issue 3, 2022, Pages 405-413]
Ellagic acid Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
Endocannabinoid Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
Endocannabinoids Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
Endometrium Investigation of the endometrial receptivity status in experimental hypothyroid-induced female rats [Volume 25, Issue 9, 2022, Pages 1077-1083]
Endoplasmic reticulum chaperone BiP Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
Endoplasmic reticulum stress Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
Energy metabolism Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
Enrichment analysis Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
Enteric Preparation of stable enteric folic acid-loaded microfiber using the electrospinning method [Volume 25, Issue 3, 2022, Pages 405-413]
Enterobacteriaceae High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
Enzyme-linked - immunosorbent assay (ELISA) New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
Epigallocatechin-3-gallate Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction [Volume 25, Issue 4, 2022, Pages 483-488]
Epilepsy Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
Epithelial-mesenchymal - transition LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
Epithelial sodium channel Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
Epitopes Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
Equol Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis [Volume 25, Issue 10, 2022, Pages 1228-1233]
ER stress Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
ER stress Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
Escherichia coli O157:H7 Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
Escitalopram Therapeutic effects of exercise-accompanied escitalopram on synaptic potency and long-term plasticity in the hippocampal CA1 area in rats under chronic restraint stress [Volume 25, Issue 12, 2022, Pages 1460-1467]
Esophageal squamous cell carcinoma MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
Ethanol Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
Eucommia ulmoides leaves Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
Eudragit Preparation of stable enteric folic acid-loaded microfiber using the electrospinning method [Volume 25, Issue 3, 2022, Pages 405-413]
Evolutionary analysis In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
Excitotoxicity Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
Exercise Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
Exercise Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
Exercise Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
Exercise Therapeutic effects of exercise-accompanied escitalopram on synaptic potency and long-term plasticity in the hippocampal CA1 area in rats under chronic restraint stress [Volume 25, Issue 12, 2022, Pages 1460-1467]
Exosome Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
Exosome Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
Exosomes A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
Exotoxin A Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]
Experimental autoimmune - encephalomyelitis Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
Expression Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
Extinction Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
Extracellular matrix Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
Extracellular signal-regulated kinases Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]

F

FABP4 Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
Farnesoid-X-receptor Biliary cirrhosis-induced cardiac abnormality in rats: Interaction between Farnesoid-X-activated receptors and the cardiac uncoupling proteins 2 and 3 [Volume 25, Issue 1, 2022, Pages 126-133]
Fas Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
Fas ligand protein Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
Fas receptor Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
Fatty liver Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
Fecal carrier High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
Fertility preservation Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
Fetuin-A Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
Fibroblast Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
Ficus carica Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
Filgrastim Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
Flavonoids Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
FOXN3 MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
Free radicals Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
Fulvic acid Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]

G

GABA receptor Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
Gallbladder dysmotility Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
Garlic Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
Gastric cancer Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
Gastric ulcer Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
Gastroparesis Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
Gata-3 Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice [Volume 25, Issue 10, 2022, Pages 1267-1274]
Gemcitabine Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
Gene delivery Recent advances in development of nano-carriers for immunogene therapy in various complex disorders [Volume 25, Issue 2, 2022, Pages 134-147]
Gene expression Fas and Fas ligand are highly expressed in lymphocytes from cervical intraepithelial neoplasia and cervical cancer patients: A possible role for immune escaping [Volume 25, Issue 3, 2022, Pages 383-389]
Gene expression Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
Genes In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
Genetic polymorphism Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
Genome-wide mutations In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
Genotypic Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
Gentamicin Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [Volume 25, Issue 1, 2022, Pages 121-125]
Giardia lamblia Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
Ginsenoside Rh2 In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
Glomerulonephritis Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
Glutamate Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
Glutamate Effect of MK-801, an antagonist of NMDA receptor in the pedunculopontine tegmental nucleus, on cardiovascular parameters in normotensive and hydralazine hypotensive rats [Volume 25, Issue 5, 2022, Pages 569-576]
Glutathione Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
Glutathione Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
Glycerol Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]
Glycolysis MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
Glycyrrhizin Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
Glycyrrihza glabra Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
Glyoxalase 1 Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
Gold Nanoparticle Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
Gonadotropin-Releasing Hormone Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
Granulocyte differentiation Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
Granulocyte-macrophage- colony-stimulating factor Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
Graphene In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
Graphene nanosheet Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
Growth MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
Guanosine Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene [Volume 25, Issue 3, 2022, Pages 399-404]
Guinea pigs Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
Gut microbiota Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]

H

H9C2 cells Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
HBs antigen PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
HBx Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
HBZ TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
Heart Arrest Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
Heat- shock proteins Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
Hemiparkinsonism The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
Hemodynamic parameters Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
Hemolysins Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
Hepatic regeneration Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
Hepatocellular Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
Hepatocellular Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
Hidden hearing loss Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
High-fat and high-fructose diet Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
High-fat diet Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]
High glucose Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
HIIT exercise The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
Hippocampal CA1 Region Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
Hippocampus The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
Hippocampus Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome [Volume 25, Issue 11, 2022, Pages 1308-1316]
Hippocampus Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
Histology Berberine protects against diclofenac sodium-induced testicular impairment in mice by its anti-oxidant and anti-apoptotic activities [Volume 25, Issue 6, 2022, Pages 767-774]
Histomorphology ovary Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
Histopathological findings Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
HIV-1 Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
HSCs/LX2 Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
HSD17B3 Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
HTLV TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
Humic acid Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
HUVECs Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [Volume 25, Issue 4, 2022, Pages 506-513]
Hyperbaric oxygen therapy Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]
Hypercholesterolemia Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
Hyperforin Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
Hypericaceae Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
Hypericin Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
Hypericum perforatum Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
Hyperlipidemia A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
Hypertension A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
Hypertension Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
Hypertension The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]
Hypertension Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
Hypertension Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
Hypertrophy LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
Hyperuricemia Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
Hypotension Effect of MK-801, an antagonist of NMDA receptor in the pedunculopontine tegmental nucleus, on cardiovascular parameters in normotensive and hydralazine hypotensive rats [Volume 25, Issue 5, 2022, Pages 569-576]
Hypothalamus Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
Hypothalamus Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance [Volume 25, Issue 9, 2022, Pages 1117-1122]
Hypothyroidism Investigation of the endometrial receptivity status in experimental hypothyroid-induced female rats [Volume 25, Issue 9, 2022, Pages 1077-1083]

I

Iba1 Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
ICU Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
IL-10 Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
IL-6 Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
Immune responses Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
Immunity Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
Immunization passive TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
Immunogene therapy Recent advances in development of nano-carriers for immunogene therapy in various complex disorders [Volume 25, Issue 2, 2022, Pages 134-147]
Immunologic factors Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
Immunotherapy In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
Immunotherapy Recent advances in development of nano-carriers for immunogene therapy in various complex disorders [Volume 25, Issue 2, 2022, Pages 134-147]
Immunotoxin In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
Inactivated SARS-CoV-2 - virus Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
Inactivated vaccine Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
Indigenous Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
Infection Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
Infection Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]
Infection control measures Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [Volume 25, Issue 2, 2022, Pages 239-244]
Infertility Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
Infertility Investigation of the endometrial receptivity status in experimental hypothyroid-induced female rats [Volume 25, Issue 9, 2022, Pages 1077-1083]
Inflammation Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
Inflammation Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
Inflammation Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
Inflammation Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
Inflammation Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]
Inflammation 6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation [Volume 25, Issue 5, 2022, Pages 629-634]
Inflammation Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
Inflammation Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]
Inflammation Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
Inflammation Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
Inflammation Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
Inflammation Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
Inflammation Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
Inflammation Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
Inflammation Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
Inflammation Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [Volume 25, Issue 8, 2022, Pages 1021-1027]
Inflammation Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
Inflammation Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
Inflammation Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
Inflammatory diseases An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
INOS Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
In situ forming hydrogel- gelling Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
Insular cortex Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
Insulin Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
Insulin Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
Insulin Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome [Volume 25, Issue 11, 2022, Pages 1308-1316]
Insulin-Like Growth Factor I Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
Insulin receptor substrate - proteins Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
Insulin-secreting cells Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
Insulin secretion Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction [Volume 25, Issue 4, 2022, Pages 483-488]
Intensive Care Units Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [Volume 25, Issue 2, 2022, Pages 239-244]
Interferon-gamma Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice [Volume 25, Issue 7, 2022, Pages 890-896]
Interstitial cajal-like cells Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
Interstitial cells of Cajal Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
Ion channel remodeling Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
Iran Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
Iron oxide Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
Ischemia Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
Ischemia Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
Ischemia JNK and p38 gene and protein expression during liver ischemia-reperfusion in a rat model treated with silibinin [Volume 25, Issue 11, 2022, Pages 1373-1381]
Ischemia/Reperfusion Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
Ischemia/Reperfusion injury Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
Isoproterenol TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]

L

Lactobacilli Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
Lactoferrin Lactoferrin mitigates ethanol-induced gastric ulcer via modulation of ROS/ICAM-1/Nrf2 signaling pathway in Wistar rats [Volume 25, Issue 12, 2022, Pages 1522-1527]
LasR Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
Lavender oil Lavender protects H9c2 cardiomyocytes against oxygen-glucose deprivation (OGD)-induced injury via targeting the JAK2/STAT3 pathway [Volume 25, Issue 2, 2022, Pages 263-267]
L-carnitine Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
LC-MS LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
L-deprenyl Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
Leptin Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
Letrozole Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
Levothyroxine sodium Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
Lipid droplet MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
Liposome Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
Liposome Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
Liposomes Anti-tumor effects of PEGylated-nanoliposomes containing ginger extract in colorectal cancer-bearing mice [Volume 25, Issue 7, 2022, Pages 890-896]
Liver Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
Liver Cirrhosis Biliary cirrhosis-induced cardiac abnormality in rats: Interaction between Farnesoid-X-activated receptors and the cardiac uncoupling proteins 2 and 3 [Volume 25, Issue 1, 2022, Pages 126-133]
Liver failure Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
Liver fibrosis Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
Local EEG The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
Long-lived IgG response PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
Long noncoding Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
Long Noncoding RNA Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma [Volume 25, Issue 3, 2022, Pages 286-294]
Long-term potentiation Therapeutic effects of exercise-accompanied escitalopram on synaptic potency and long-term plasticity in the hippocampal CA1 area in rats under chronic restraint stress [Volume 25, Issue 12, 2022, Pages 1460-1467]
Low-density lipoprotein - receptors Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
LOXL2 protein LOXL2 silencing suppresses angiotensin II-induced cardiac hypertrophy through the EMT process and TGF-β1/Smad3/NF-κB pathway [Volume 25, Issue 8, 2022, Pages 964-969]
LSD1 inhibitor Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]

M

Macrophage Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
Macrophage Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
Macrophages Dioscin ameliorates slow transit constipation in mice by up-regulation of the BMP2 secreted by muscularis macrophages [Volume 25, Issue 9, 2022, Pages 1132-1140]
MAGI2-AS3 MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway [Volume 25, Issue 1, 2022, Pages 46-52]
Magnetic vanoparticles A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
Malaysia Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
Malondialdehyde Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
Mangostin Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
MAPK TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
MAP kinase signaling - system Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [Volume 25, Issue 8, 2022, Pages 1021-1027]
MAPK/NF-κB signaling Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
MARCH-1 Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
Mast cell 6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation [Volume 25, Issue 5, 2022, Pages 629-634]
MBL Phenotypic and genotypic investigation of metallo-β-lactamases in Pseudomonas aeruginosa clinical isolates in Bushehr, Iran [Volume 25, Issue 10, 2022, Pages 1196-1200]
MDMA Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
Mechanical Strength Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
Medical equipment Molecular typing of clinical and environmental isolates of Klebsiella pneumoniae producing ESBLs by PFGE [Volume 25, Issue 2, 2022, Pages 208-213]
Medicinal Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
Melanoma Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
Melatonin Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
Memory Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
Mesenchymal stem cell Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
Mesenchymal stem cell Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
Mesenchymal stem cells Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
Mesenchymal stem cells A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
Mesenchymal stem cells Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
Mesenchymal stem cells Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
Mesoporous structure Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
Metabolic zone MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
Metabolite profiling LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
Metallo-β-lactamase Phenotypic and genotypic investigation of metallo-β-lactamases in Pseudomonas aeruginosa clinical isolates in Bushehr, Iran [Volume 25, Issue 10, 2022, Pages 1196-1200]
Metformin Metformin exerts synergistic anti-proliferative effects with Liraglutide in human umbilical vein endothelial cells (HUVECs) [Volume 25, Issue 4, 2022, Pages 506-513]
Metformin Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
Methicillin-resistant - Staphylococcus aureus Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
Methicillin-resistant - Staphylococcus aureus High prevalence and expression of antiseptic resistance genes among infectious t037/ST239 methicillin-resistant Staphylococcus aureus (MRSA) strains in North Khorasan Province, Iran [Volume 25, Issue 6, 2022, Pages 775-780]
Methotrexate Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
Methotrexate In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
Methylglyoxal Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal [Volume 25, Issue 2, 2022, Pages 179-186]
Methylglyoxal Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
MF59 PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
Mice Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
Mice Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
Microarray Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
Microbial sensitivity tests Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
Microfiber Preparation of stable enteric folic acid-loaded microfiber using the electrospinning method [Volume 25, Issue 3, 2022, Pages 405-413]
Microglia Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [Volume 25, Issue 9, 2022, Pages 1091-1096]
MicroRNA MicroRNA-96: A therapeutic and diagnostic tumor marker [Volume 25, Issue 1, 2022, Pages 3-13]
MicroRNA Wound dressings incorporating microRNAs: Innovative therapy for diabetic wound treatment [Volume 25, Issue 9, 2022, Pages 1042-1044]
Midazolam Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]
Migration Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]
Milk Thistle A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
MiR-574-5p MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
Mitochondrial biogenesis Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
Mitochondrial dynamics MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
Mitochondrial dysfunction Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
Mitochondrial functions An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways [Volume 25, Issue 1, 2022, Pages 14-26]
Mitochondrial uncoupling proteins Biliary cirrhosis-induced cardiac abnormality in rats: Interaction between Farnesoid-X-activated receptors and the cardiac uncoupling proteins 2 and 3 [Volume 25, Issue 1, 2022, Pages 126-133]
Mitophagy MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
Molecular docking Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
Molecular docking Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
Monoclonal antibody Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
Monoclonal antibody Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
Monosodium glutamate Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
Morphine Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
Mst1 Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
Multiple sclerosis Neuroinflammation Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
MyD88 TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
Myocardial infarction Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
Myocardial schemia Oxidative stress Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]

N

Na Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
N-acetylcysteine Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
NAD⁺ Ameliorating effect of 6-week swimming exercise on mice with experimental autoimmune encephalomyelitis (EAE) by reducing fetuin-A and increasing AMPK & NAD⁺ levels in liver tissue [Volume 25, Issue 8, 2022, Pages 1016-1020]
NADPH oxidase Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
NAFLD Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance [Volume 25, Issue 9, 2022, Pages 1117-1122]
Naloxone Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
Nanobody Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
Nano-carriers Recent advances in development of nano-carriers for immunogene therapy in various complex disorders [Volume 25, Issue 2, 2022, Pages 134-147]
Nanoemulgel formulation Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
Nano-hybrid Fabrication and evaluation of bioresorbable scaffolds for interventional cardiology application with sufficient drug release [Volume 25, Issue 3, 2022, Pages 372-382]
Nanoparticle Nanoencapsulation of n-butanol extract of Symphytum kurdicum and Symphytum asperrimum: Focus on phytochemical analysis, anti-oxidant and antibacterial activity [Volume 25, Issue 3, 2022, Pages 364-371]
Nanovaccine A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
Nanovaccine Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
Nasal and parenteral immunization A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
Nasopharyngeal carcinoma Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
Natural toxin Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article [Volume 25, Issue 12, 2022, Pages 1402-1415]
Necrotizing Enterocolitis Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
Neobavaisoflavone Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [Volume 25, Issue 8, 2022, Pages 1021-1027]
Neoplasms A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
Nephropathy Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
Nephroprotective Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
Nephrotoxicity Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
Nephrotoxicity Metabolite profiling and nephroprotective potential of Glycyrrhiza glabra L. roots against cisplatin-induced nephrotoxicity in vitro and in vivo [Volume 25, Issue 11, 2022, Pages 1286-1298]
Nettle A review of the effects of Urtica dioica (nettle) in metabolic syndrome [Volume 25, Issue 5, 2022, Pages 543-553]
Network pharmacology Effect of Eucommia ulmoides leaves on hyperuricemia and kidney injury induced by a high-fat/high-fructose diet in rats [Volume 25, Issue 4, 2022, Pages 527-535]
Neural tissue engineering Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
Neurogenesis Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome [Volume 25, Issue 11, 2022, Pages 1308-1316]
Neuroinflammation Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
Neuroinflammation Ameliorative effect of carveol on scopolamine induced memory impairment in rats [Volume 25, Issue 12, 2022, Pages 1504-1512]
Neuroinflammation Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
Neuroinflammatory - diseases Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
Neuronal plasticity Therapeutic effects of exercise-accompanied escitalopram on synaptic potency and long-term plasticity in the hippocampal CA1 area in rats under chronic restraint stress [Volume 25, Issue 12, 2022, Pages 1460-1467]
Neuroprotection Chromone derivatives suppress neuroinflammation and improve mitochondrial function in the sporadic form of Alzheimer’s disease under experimental conditions [Volume 25, Issue 7, 2022, Pages 871-881]
Neurotoxicity Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
Neurotoxicity Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
Neutralizing antibodies Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
Neutrophils Neutrophil depletion reduces interstitial cajal-like cell injury and alleviates inflammation-induced motor dysfunction in guinea-pig gallbladder during acute cholecystitis [Volume 25, Issue 4, 2022, Pages 435-441]
NF-E2-related factor 2 Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
NF-kappa B Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [Volume 25, Issue 8, 2022, Pages 1021-1027]
NF-kappa B TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
NF-kB Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
NF-kB Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
NF-ƙB C-Kit+ cells can modulate asthmatic condition via differentiation into pneumocyte-like cells and alteration of inflammatory responses via ERK/NF-ƙB pathway [Volume 25, Issue 1, 2022, Pages 96-102]
NF-ƙB Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
NF-κB Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
Nicotine Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
Nilotinib Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
Nitric oxide Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
Nitric oxide Reno-protective effects of GLP-1 receptor agonist and anti-platelets in experimentally induced diabetic kidney disease in male albino rats [Volume 25, Issue 12, 2022, Pages 1487-1497]
NLR Family Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
NLRP3 Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
NLRP3 inflammasome Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation [Volume 25, Issue 10, 2022, Pages 1260-1266]
NLRP3 inflammasome Nuclear factor - kappa B Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
NMDA receptor Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
NMDA receptor Effect of MK-801, an antagonist of NMDA receptor in the pedunculopontine tegmental nucleus, on cardiovascular parameters in normotensive and hydralazine hypotensive rats [Volume 25, Issue 5, 2022, Pages 569-576]
Noise-induced hearing loss Metabotropic glutamate receptor: A new possible therapeutic target for cochlear synaptopathy [Volume 25, Issue 1, 2022, Pages 75-83]
Nosocomial infection High prevalence and expression of antiseptic resistance genes among infectious t037/ST239 methicillin-resistant Staphylococcus aureus (MRSA) strains in North Khorasan Province, Iran [Volume 25, Issue 6, 2022, Pages 775-780]
Nrf2 Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
Nrf2 Dapsone reduced cuprizone-induced demyelination via targeting Nrf2 and IKB in C57BL/6 mice [Volume 25, Issue 6, 2022, Pages 675-682]
Nrf2 Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
Nrf2 Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
Nrf2 Crocin attenuates endoplasmic reticulum stress in methylglyoxal induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways [Volume 25, Issue 11, 2022, Pages 1341-1348]
NSCLC Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]

O

Obesity Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
Obesity The effects of ginger and its constituents in the prevention of metabolic syndrome: A review [Volume 25, Issue 6, 2022, Pages 664-674]
Obesity Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
Obesity Synthesis, molecular docking, and pharmacological evaluation of 5-(4-(2-(5-ethyl pyridine-2-yl) ethoxy) benzyl)-3-(phenylsulfonyl) thiazolidine-2, 4-dione against HFD-induced diabesity via interaction with the CB1 receptor [Volume 25, Issue 8, 2022, Pages 1028-1036]
Obesity Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
Occludin Aerobic training improves blood-brain barrier and neuronal apoptosis in experimental autoimmune encephalomyelitis [Volume 25, Issue 2, 2022, Pages 245-253]
OHSS Coenzyme Q10 improves ovarian histology and attenuates the expression of angiogenesis-associated proteins in the ovary of rats with experimental hyperstimulation syndrome [Volume 25, Issue 8, 2022, Pages 989-996]
Olanzapine Effect of alpha-mangostin on olanzapine-induced metabolic disorders in rats [Volume 25, Issue 2, 2022, Pages 198-207]
Olea europaea Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
Omega-3 Fatty Acids Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
Oncogene Protein v-akt MiR-574-5p promotes cell proliferation by negatively regulating small C-terminal domain phosphatase 1 in esophageal squamous cell carcinoma [Volume 25, Issue 10, 2022, Pages 1243-1250]
Oral colonization Oral colonization of Acinetobacter baumannii in intensive care units: Risk factors, incidence, molecular epidemiology, association with the occur of pneumonia and sepsis, and infection control measures [Volume 25, Issue 2, 2022, Pages 239-244]
Oral vaccine Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
Osteoarthritis Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis [Volume 25, Issue 10, 2022, Pages 1228-1233]
Osteogenesis Identification and validation of autophagy-related genes during osteogenic differentiation of bone marrow mesenchymal stem cells [Volume 25, Issue 11, 2022, Pages 1364-1372]
Osteosarcoma 1,3,5-triazines inhibit osteosarcoma and avert lung metastasis in a patient-derived orthotopic xenograft mouse model with favorable pharmacokinetics [Volume 25, Issue 3, 2022, Pages 295-301]
Ototoxicity Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [Volume 25, Issue 1, 2022, Pages 121-125]
Ovarian Follicle Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
Ovariectomised rats Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis [Volume 25, Issue 10, 2022, Pages 1228-1233]
Ovariectomy Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
Ovary Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
Oxidative Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway [Volume 25, Issue 9, 2022, Pages 1097-1103]
Oxidative Enzymes Protective effect of protein hydrolysates from Litopenaeus vannamei waste on oxidative status, glucose regulation, and autophagy genes in non-alcoholic fatty liver disease in Wistar rats [Volume 25, Issue 8, 2022, Pages 954-963]
Oxidative stress Carvedilol attenuates acrylamide-induced brain damage through inhibition of oxidative, inflammatory, and apoptotic mediators [Volume 25, Issue 1, 2022, Pages 60-67]
Oxidative stress Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
Oxidative stress Calcium dobesilate ameliorates hepatorenal injury induced by carbon tetrachloride in mice [Volume 25, Issue 2, 2022, Pages 148-154]
Oxidative stress Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
Oxidative stress The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
Oxidative stress Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
Oxidative stress Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model [Volume 25, Issue 3, 2022, Pages 320-329]
Oxidative stress Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
Oxidative stress Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
Oxidative stress Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
Oxidative stress Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
Oxidative stress Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
Oxidative stress Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
Oxidative stress Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
Oxidative stress Effects of different-intensity exercise and creatine supplementation on mitochondrial biogenesis and redox status in mice [Volume 25, Issue 8, 2022, Pages 1009-1015]
Oxidative stress Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
Oxidative stress Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
Oxidative stress MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection [Volume 25, Issue 11, 2022, Pages 1382-1388]
Oxidative stress Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
Ozone therapy Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]

P

P53 Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [Volume 25, Issue 4, 2022, Pages 497-505]
Paclitaxel Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
Pancreatic duodenal homeobox protein-1 Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction [Volume 25, Issue 4, 2022, Pages 483-488]
Paraquat Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
Parkinson’s disease Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
Particulate Matter Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10 [Volume 25, Issue 4, 2022, Pages 460-467]
Patient-derived xenograft Combination of T-DM1 and platinum-based chemotherapy in patient-derived xenograft models of muscle-invasive bladder cancer [Volume 25, Issue 7, 2022, Pages 816-821]
Pattern recognition receptors Acute lung injury induced by acute uremia and renal ischemic-reperfusion injury: The role of toll-like receptors 2 and 4, and oxidative stress [Volume 25, Issue 5, 2022, Pages 643-651]
PBP2a Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
Pedunculopontine tegmental nucleus Effect of MK-801, an antagonist of NMDA receptor in the pedunculopontine tegmental nucleus, on cardiovascular parameters in normotensive and hydralazine hypotensive rats [Volume 25, Issue 5, 2022, Pages 569-576]
Penile erection Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
Pergularia tomentosa LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
Periodontitis Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway [Volume 25, Issue 5, 2022, Pages 635-642]
PFGE High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran [Volume 25, Issue 12, 2022, Pages 1416-1423]
Phage display library Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
Pharmaceutical preparations A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
Pharmacokinetics Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]
Phenotypic Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
Photochemical - internalization Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
Photodynamic Therapy Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
Physioxia Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model [Volume 25, Issue 2, 2022, Pages 155-163]
Phytochemicals LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect [Volume 25, Issue 12, 2022, Pages 1433-1441]
Phytotherapy Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [Volume 25, Issue 6, 2022, Pages 683-689]
PI3K 1,3,5-triazines inhibit osteosarcoma and avert lung metastasis in a patient-derived orthotopic xenograft mouse model with favorable pharmacokinetics [Volume 25, Issue 3, 2022, Pages 295-301]
PI3K/Akt Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway [Volume 25, Issue 5, 2022, Pages 635-642]
PI3K/Akt/mTOR Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance [Volume 25, Issue 9, 2022, Pages 1117-1122]
Pichia pastoris TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
Plant extracts A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
Plasmids Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
Platelet activation Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]
PLGA Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [Volume 25, Issue 4, 2022, Pages 442-450]
PNC27 peptide Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
Polarization Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
Polycystic ovary syndrome Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
Polycystic ovary syndrome Prenatal Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
Polymer In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
Polyurethane foam Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
Polyvinyl alcohol Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
Portal Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
Portulaca oleracea Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
Post-insertion Preparation, characterization, and biodistribution of glutathione PEGylated nanoliposomal doxorubicin for brain drug delivery with a post-insertion approach [Volume 25, Issue 3, 2022, Pages 302-312]
Postsynaptic density protein-95 Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
Post-traumatic stress disorder Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
PPARγ Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
PPARγ Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
PPD PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [Volume 25, Issue 11, 2022, Pages 1326-1333]
Prefrontal cortex Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
Prepulse inhibition Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
Prognosis MicroRNA-96: A therapeutic and diagnostic tumor marker [Volume 25, Issue 1, 2022, Pages 3-13]
Programmed cell death - ligand-1 Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
Pro-inflammatory cytokines Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
Proliferation Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
Propylthiouracil Investigation of the endometrial receptivity status in experimental hypothyroid-induced female rats [Volume 25, Issue 9, 2022, Pages 1077-1083]
Prosopis africana Cobalt exposure triggers impairments in cognitive and anxiety-like behaviors, brain oxidative stress and inflammation, and hippocampo-amygdala histomorphological alterations: Protective role of aqueous Prosopis africana seed extract [Volume 25, Issue 12, 2022, Pages 1528-1536]
Protective Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article [Volume 25, Issue 12, 2022, Pages 1402-1415]
Protein Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
Protoporphyrin-IX Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization [Volume 25, Issue 8, 2022, Pages 970-979]
Pseudomonas aeruginosa Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
Pseudomonas aeruginosa Phenotypic and genotypic investigation of metallo-β-lactamases in Pseudomonas aeruginosa clinical isolates in Bushehr, Iran [Volume 25, Issue 10, 2022, Pages 1196-1200]
Pseudomonas aeruginosa Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]
Pulmonary arterial - hypertension Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress [Volume 25, Issue 6, 2022, Pages 755-761]
Pulmonary edema Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
Purslane Effects of Portulaca oleracea L. (purslane) on the metabolic syndrome: A review [Volume 25, Issue 11, 2022, Pages 1275-1285]
Putrescine Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
Pyrazolone New pyrazolone derivatives, synthesis, characterization, and neuroprotective effect against PTZ- induced neuroinflammation in mice [Volume 25, Issue 12, 2022, Pages 1424-1432]
Pyrin domain containing 3 Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]
Pyroptosis Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
Pyroptosis Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [Volume 25, Issue 10, 2022, Pages 1215-1221]

R

Radiosensitivity Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
Radiotherapy Flow cytometric assessment of DNA double-strand break and repair kinetics in prediction of intrinsic radiosensitivity [Volume 25, Issue 9, 2022, Pages 1104-1109]
Ramelteon Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity [Volume 25, Issue 10, 2022, Pages 1183-1189]
Ranolazine Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]
Rat Chronic treatment with coenzyme Q10 mitigates the behavioral dysfunction of global cerebral ischemia/reperfusion injury in rats [Volume 25, Issue 1, 2022, Pages 39-45]
Rat Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
Rat Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
Rat The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
Rat Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
Rat Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
Rat Effect of electrical stimulation of central nucleus of the amygdala on morphine conditioned place preference in male rats [Volume 25, Issue 5, 2022, Pages 604-610]
Rat Astragaloside IV regulates autophagy-mediated proliferation and apoptosis in a rat model of PCOS by activating the PPARγ pathway [Volume 25, Issue 7, 2022, Pages 882-889]
Rat Does Ambroxol alleviate kidney ischemia-reperfusion injury in rats? [Volume 25, Issue 8, 2022, Pages 1037-1041]
Rat Safety assessment of the Quercus brantii gall hydroalcoholic extract: Single and repeated oral dose toxicity studies [Volume 25, Issue 11, 2022, Pages 1389-1395]
Rats Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
RBD Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
Reactive Oxygen Species Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
Recombinant fusion peptide A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
Recombinant Ib-AMP4 Ib-AMP4 antimicrobial peptide as a treatment for skin and systematic infection of methicillin-resistant Staphylococcus aureus (MRSA) [Volume 25, Issue 2, 2022, Pages 232-238]
Recombinant protein Decrescent role of recombinant HSP60 antibody against atherosclerosis in high-cholesterol diet immunized rabbits [Volume 25, Issue 1, 2022, Pages 32-38]
Recombinant protein Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
Recombinant proteins TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
Recombinant proteins Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
REM Sleep Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
REM sleep deprivation Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]
Renal fibrosis Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [Volume 25, Issue 11, 2022, Pages 1317-1325]
Renal tubular epithelial cell Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
Repeated dose toxicity Safety assessment of the Quercus brantii gall hydroalcoholic extract: Single and repeated oral dose toxicity studies [Volume 25, Issue 11, 2022, Pages 1389-1395]
Reperfusion Potential protective effect of astaxanthin on ovary ischemia-reperfusion injury [Volume 25, Issue 2, 2022, Pages 173-178]
Reperfusion Mesenchymal stem cells versus their conditioned medium in the treatment of ischemia/reperfusion injury: Evaluation of efficacy and hepatic specific gene expression in mice [Volume 25, Issue 7, 2022, Pages 799-807]
Reperfusion JNK and p38 gene and protein expression during liver ischemia-reperfusion in a rat model treated with silibinin [Volume 25, Issue 11, 2022, Pages 1373-1381]
Replication Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]
Resveratrol The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
RFamide-related peptide-3 Maternal aromatase inhibition via letrozole altered RFamide-related peptide-3 and gonadotropin-releasing hormone expression in pubertal female rats [Volume 25, Issue 1, 2022, Pages 110-120]
RNA Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
RNA Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
RNAi-based therapeutics Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
RNA-Seq Analysis of transcriptome characteristics of UTI therapy for cerebral injury after CA/ROSC based on RNA-seq technique [Volume 25, Issue 6, 2022, Pages 715-722]
ROS Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis [Volume 25, Issue 1, 2022, Pages 103-109]
ROS Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
ROS Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
Rotavirus Calcium-sensing receptor acts as an antiviral factor for rotavirus infections and participates in cellular antiviral response [Volume 25, Issue 8, 2022, Pages 997-1001]

S

Saffron Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
Saffron Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
Saffron Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
Safranal Saffron nephroprotective effects against medications and toxins: A review of preclinical data [Volume 25, Issue 4, 2022, Pages 419-434]
Safranal Interaction of saffron and its constituents with Nrf2 signaling pathway: A review [Volume 25, Issue 7, 2022, Pages 789-798]
Sanguinarine Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [Volume 25, Issue 6, 2022, Pages 781-788]
Saroglitazar Saroglitazar ameliorates monosodium glutamate-induced obesity and associated inflammation in Wistar rats: Plausible role of NLRP3 inflammasome and NF- κB [Volume 25, Issue 7, 2022, Pages 827-841]
SARS-CoV-2 Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
SARS-CoV-2 In silico analysis of the substitution mutations and evolutionary trends of the SARS-CoV-2 structural proteins in Asia [Volume 25, Issue 11, 2022, Pages 1299-1307]
Scaffold A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
Sciatic nerve Neuroprotective effects of celastrol on sciatic nerve transection model in male Wistar rats [Volume 25, Issue 10, 2022, Pages 1251-1259]
Secretory IgA Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
Selegiline Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury [Volume 25, Issue 1, 2022, Pages 53-59]
Self-assembled nanomicelles A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
Sema3A Intraperitoneal ozone injection prevents rem sleep deprivation - induced spatial learning and memory deficits by suppressing the expression of Sema3A in the hippocampus in rats [Volume 25, Issue 8, 2022, Pages 980-988]
Sepsis Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]
Sepsis Protective effect of N-acetylcysteine on acute lung injury in septic rats by inhibiting inflammation, oxidation, and apoptosis [Volume 25, Issue 7, 2022, Pages 859-864]
Sepsis-associated-encephalopathy Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]
Serotonin Mesenchymal stem cells and their conditioned medium as potential therapeutic strategies in managing comorbid anxiety in rat sepsis induced by cecal ligation and puncture [Volume 25, Issue 6, 2022, Pages 690-697]
Serum Developing novel liquid biopsy by selective capture of viral RNA on magnetic beads to detect COVID-19 [Volume 25, Issue 6, 2022, Pages 762-766]
Shiga toxin Immunogenicity of inactivated Escherichia coli O157:H7 with Stx2B microparticle in mice [Volume 25, Issue 9, 2022, Pages 1069-1076]
Signaling pathways Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways [Volume 25, Issue 10, 2022, Pages 1222-1227]
Silibinin JNK and p38 gene and protein expression during liver ischemia-reperfusion in a rat model treated with silibinin [Volume 25, Issue 11, 2022, Pages 1373-1381]
Silybum marianum L A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
Silymarin A review of therapeutic potentials of milk thistle (Silybum marianum L.) and its main constituent, silymarin, on cancer, and their related patents [Volume 25, Issue 10, 2022, Pages 1166-1176]
Sinapic acid Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes [Volume 25, Issue 5, 2022, Pages 611-620]
Single-chain variable - fragment Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
Single-chain variable-fragment Anti-Acinetobacter baumannii single-chain variable fragments show direct bactericidal activity [Volume 25, Issue 9, 2022, Pages 1141-1149]
Single-domain antibodies In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
Single domain antibody Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [Volume 25, Issue 3, 2022, Pages 313-319]
Sirolimus Rapamycin-filgrastim combination therapy ameliorates portal hypertension-induced splenomegaly: Role of β actin and S100A9 proteins modulation [Volume 25, Issue 6, 2022, Pages 732-744]
Sirtuin 1 Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway [Volume 25, Issue 2, 2022, Pages 193-197]
Sirtuins The effects of combined resveratrol and high intensity interval training on the hippocampus in aged male rats: An investigation into some signaling pathways related to mitochondria [Volume 25, Issue 2, 2022, Pages 254-262]
Sitagliptin Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]
Skin and systematic infection Ib-AMP4 antimicrobial peptide as a treatment for skin and systematic infection of methicillin-resistant Staphylococcus aureus (MRSA) [Volume 25, Issue 2, 2022, Pages 232-238]
SKP1 inhibitor 6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation [Volume 25, Issue 5, 2022, Pages 629-634]
SLC29A1 protein Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells [Volume 25, Issue 4, 2022, Pages 536-542]
Sleep deprivation Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
Sleep deprivation Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
Smart hydrogels Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
Smooth Muscle Effects of cannabinoid and vanilloid receptor antagonists on nicotine induced relaxation response enhancement in rabbit corpus cavernosum [Volume 25, Issue 4, 2022, Pages 514-519]
Social behavior Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
Sodium butyrate Intra-mPFC injection of sodium butyrate promotes BDNF expression and ameliorates extinction recall impairment in an experimental paradigm of post-traumatic stress disorder [Volume 25, Issue 9, 2022, Pages 1150-1158]
Soluble Fzd7 Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells [Volume 25, Issue 2, 2022, Pages 187-192]
Somatosensory cortex TRPV1 Acupuncture points injection mitigates chronic pain through transient receptor potential V1 in mice [Volume 25, Issue 4, 2022, Pages 451-459]
Spatial Memory Effect of multi-epitope derived from HIV-1 on REM sleep deprivation-induced spatial memory impairment with respect to the level of immune factors in mice [Volume 25, Issue 2, 2022, Pages 164-172]
Spermatogenesis Impact of caffeic acid on the testicular damages in D-galactose induced aging model in mice [Volume 25, Issue 10, 2022, Pages 1190-1195]
Spermidine/Spermine-N(1) Role of exogenous putrescine in the status of energy, DNA damage, inflammation, and spermidine/spermine-n(1)- acetyltransferase in brain ischemia-reperfusion in rats [Volume 25, Issue 5, 2022, Pages 597-603]
Spider venoms Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]
Spinosin Spinosin ameliorates insulin resistance by suppressing reactive oxygen species-associated inflammation [Volume 25, Issue 7, 2022, Pages 850-858]
SPIONs Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
Spleen Spleen extracellular matrix provides a supportive microenvironment for β-cell function [Volume 25, Issue 9, 2022, Pages 1159-1165]
Staphylococcal infections Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
Staphylococcus aureus Ib-AMP4 antimicrobial peptide as a treatment for skin and systematic infection of methicillin-resistant Staphylococcus aureus (MRSA) [Volume 25, Issue 2, 2022, Pages 232-238]
Staphylococcus aureus Identification of two neutralizing human single-chain variable fragment antibodies targeting Staphylococcus aureus alpha-hemolysin [Volume 25, Issue 10, 2022, Pages 1207-1214]
StaR Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
Startle reflex Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
STAT3 Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]
Stem cell factor Atractylodes chinensis volatile oil up-regulated IGF-1 to improve diabetic gastroparesis in rats [Volume 25, Issue 4, 2022, Pages 520-526]
Steroids Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
St. John’s wort Hypericum perforatum: Traditional uses, clinical trials, and drug interactions [Volume 25, Issue 9, 2022, Pages 1045-1058]
Stomach neoplasms Transcriptome Inconsistency in the expression pattern of a five-lncRNA signature as a potential diagnostic biomarker for gastric cancer patients in bioinformatics and in vitro [Volume 25, Issue 6, 2022, Pages 704-714]
Stride-length The effects of betulinic acid chronic administration on the motor, non-motor behaviors, and globus pallidus local field potential power in a rat model of hemiparkinsonism [Volume 25, Issue 11, 2022, Pages 1357-1363]
Subchondral bone Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis [Volume 25, Issue 10, 2022, Pages 1228-1233]
Sumac Rhus coriaria extracts inhibit quorum sensing related virulence and biofilm production in drug-resistant Pseudomonas aeruginosa recovered from burn wounds [Volume 25, Issue 11, 2022, Pages 1349-1356]
Survivin Over-expression of survivin could prevent the oxidative stress and toxicity of rotenone in SH-SY5Y cells [Volume 25, Issue 7, 2022, Pages 842-849]
Synapsin I Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
Synaptic plasticity Synaptic plasticity and cognitive impairment consequences to acute kidney injury: Protective role of ellagic acid [Volume 25, Issue 5, 2022, Pages 621-628]
Synaptophysin Effects of citicoline administration on synaptic proteins in rapid eye movement sleep-deprived rats [Volume 25, Issue 5, 2022, Pages 562-568]
Systemic inflammatory-response Comparative treatment with hyperbaric oxygen therapy in a model of systemic loxoscelism in rats [Volume 25, Issue 12, 2022, Pages 1452-1459]

T

Tanshinone Ⅰ Protective effects of tanshinone I against cisplatin-induced nephrotoxicity in mice [Volume 25, Issue 3, 2022, Pages 414-418]
Tapentadol Effects of CYP2C19 variants on the metabolism of tapentadol in vitro [Volume 25, Issue 5, 2022, Pages 659-663]
Targeted cancer diagnostic Conjugated PNC-27 peptide/PEI-Superparamagnetic iron oxide nanoparticles (SPIONs) as a double targeting agent for early cancer diagnosis: In vitro study [Volume 25, Issue 10, 2022, Pages 1234-1242]
Targeted therapy Combination of T-DM1 and platinum-based chemotherapy in patient-derived xenograft models of muscle-invasive bladder cancer [Volume 25, Issue 7, 2022, Pages 816-821]
Tax TAX and HBZ: hFc Ɣ 1 proteins as targets for passive immunotherapy [Volume 25, Issue 5, 2022, Pages 586-596]
T-box transcription factor Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice [Volume 25, Issue 10, 2022, Pages 1267-1274]
T-DM1 Combination of T-DM1 and platinum-based chemotherapy in patient-derived xenograft models of muscle-invasive bladder cancer [Volume 25, Issue 7, 2022, Pages 816-821]
Temperature-responsive- systems Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
Testes Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
Testis Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
Tetani Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
Tetratricopeptide repeat domain 9A (TTC9A) Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice [Volume 25, Issue 6, 2022, Pages 698-703]
TGF-beta Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [Volume 25, Issue 4, 2022, Pages 474-482]
TGF-β Conjugated linoleic acid modifies transcriptional cytokine profile and induces early specific secretory IgA response in Giardia lamblia infected mice [Volume 25, Issue 12, 2022, Pages 1468-1476]
TGF β/Smad3C Exosomes of Whartons’ jelly mesenchymal stem cell reduce the NOX genes in TGF-β-induced hepatic fibrosis [Volume 25, Issue 12, 2022, Pages 1498-1503]
Theaflavin Theaflavin promoted apoptosis in nasopharyngeal carcinoma unexpectedly via inducing autophagy in vitro [Volume 25, Issue 1, 2022, Pages 68-74]
Therapy Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence [Volume 25, Issue 8, 2022, Pages 913-933]
Thiazole compound Thiazole derivative based topical nanoemulgel for inhibition of bacterial virulence in surface infections [Volume 25, Issue 3, 2022, Pages 352-363]
Thymoquinone Thymoquinone-loaded mesenchymal stem cell-derived exosome as an efficient nano-system against breast cancer cells [Volume 25, Issue 6, 2022, Pages 723-731]
Tight junction proteins Ulinastatin alleviates pulmonary edema by reducing pulmonary permeability and stimulating alveolar fluid clearance in a rat model of acute lung injury [Volume 25, Issue 8, 2022, Pages 1002-1008]
Time restriction Effects of caloric and time restriction diets on kidney health in rat model of postmenopausal acute kidney injury: An apoptosis and histopathological study [Volume 25, Issue 3, 2022, Pages 390-398]
Tinnitus Does insular cortex lesion cause tinnitus in rats? [Volume 25, Issue 10, 2022, Pages 1177-1182]
Tissue engineering A smart magnetic hydrogel containing exosome promotes osteogenic commitment of human adipose-derived mesenchymal stem cells [Volume 25, Issue 9, 2022, Pages 1123-1131]
Tissue regeneration Highly porous bio-glass scaffolds fabricated by polyurethane template method with hydrothermal treatment for tissue engineering uses [Volume 25, Issue 12, 2022, Pages 1513-1521]
TMAO Lactobacilli and Bifidobacterium as anti- atherosclerotic agents [Volume 25, Issue 8, 2022, Pages 934-946]
TNBC Synergistic anticancer mechanisms of curcumol and paclitaxel in triple-negative breast cancer treatment may involve down-regulating ZBTB7A expression via the NF-B signaling pathway [Volume 25, Issue 5, 2022, Pages 652-658]
TNF-α Inhibitory effects of Ficus carica and Olea europaea on pro-inflammatory cytokines: A review [Volume 25, Issue 3, 2022, Pages 268-275]
Toll-Like Receptor Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [Volume 25, Issue 5, 2022, Pages 577-585]
Toll-Like Receptor TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis [Volume 25, Issue 11, 2022, Pages 1334-1340]
Toll-like receptor 4 Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats [Volume 25, Issue 11, 2022, Pages 1396-1401]
Toxicity studies Safety assessment of the Quercus brantii gall hydroalcoholic extract: Single and repeated oral dose toxicity studies [Volume 25, Issue 11, 2022, Pages 1389-1395]
Toxin Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
Tramadol Cross-talk between down-regulation of steroidogenic genes expression and oxidative and apoptotic biomarkers in testes induced by administration of tramadol and boldenone and their combination in male albino rats [Volume 25, Issue 7, 2022, Pages 808-815]
Transient outward - potassium current Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
Treatment Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering [Volume 25, Issue 3, 2022, Pages 330-340]
Triblock copolymer Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers [Volume 25, Issue 3, 2022, Pages 341-351]
TRPM7 Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
TRPV1 Transient receptor potential vanilloid type-1 regulates periodontal disease damage via the PI3K/AKT signaling pathway [Volume 25, Issue 5, 2022, Pages 635-642]
Tuberculosis A novel nanomicelle composed from PEGylated TB di-peptide could be successfully used as a BCG booster [Volume 25, Issue 2, 2022, Pages 223-231]
Tubular necrosis Alleviation of cisplatin-induced hepatotoxicity and nephrotoxicity by L-carnitine [Volume 25, Issue 7, 2022, Pages 897-903]
Tumor In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
Tumor In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [Volume 25, Issue 12, 2022, Pages 1442-1451]
Tunicamycin Protective and therapeutic role of melatonin against tunicamycin-induced ER stress in testicular tissue of rats [Volume 25, Issue 2, 2022, Pages 214-222]
Type 2 diabetes mellitus β-cell Epigallocatechin-3-gallate alleviates type 2 diabetes mellitus via β-cell function improvement and insulin resistance reduction [Volume 25, Issue 4, 2022, Pages 483-488]
Tyrosinase Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line [Volume 25, Issue 4, 2022, Pages 489-496]
Tyrosine kinase inhibitor Investigating the potential therapeutic role of targeting STAT3 for overcoming drug resistance by regulating energy metabolism in chronic myeloid leukemia cells [Volume 25, Issue 7, 2022, Pages 904-912]

V

Vaccine Immunopotentiating properties of chimeric OprF-OprI-PopB protein against Pseudomonas aeruginosa PAO1 in the infected burned rat model [Volume 25, Issue 3, 2022, Pages 276-285]
Vaccine Major pathogenic Clostridia in human and progress toward the clostridial vaccines [Volume 25, Issue 9, 2022, Pages 1059-1068]
Vaccine formulation Improvement of the inactivated SARS-CoV-2 vaccine potency through formulation in alum/naloxone adjuvant; Robust T cell and anti-RBD IgG responses [Volume 25, Issue 5, 2022, Pages 554-561]
Vaccines Recombinant expression of SARS-CoV-2 Receptor Binding Domain (RBD) in Escherichia coli and its immunogenicity in mice [Volume 25, Issue 9, 2022, Pages 1110-1116]
Vascular endothelial - Growth factor receptor-2 In vitro evaluation of anti-angiogenesis property of anti-VEGFR2 nanobody-conjugated H40-PEG carrier loaded with methotrexate [Volume 25, Issue 12, 2022, Pages 1477-1486]
Vascular endothelial growth - factor (VEGF) In vivo solid tumor targeting with recombinant VEGF-diphtheria immunotoxin [Volume 25, Issue 1, 2022, Pages 27-31]
Vasopressins Cross talk of vasopressin conditioned cell therapy in ischemic heart disease: Role of oxidative stress markers [Volume 25, Issue 9, 2022, Pages 1084-1090]
Venous thrombosis Effects of wasp venom on venous thrombosis in rats [Volume 25, Issue 7, 2022, Pages 822-826]
Ventricular hypertrophy Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes [Volume 25, Issue 10, 2022, Pages 1201-1206]
Verocytotoxin (VT)-producing Escherichia coli (VTEC) Genotypic and phenotypic characterization of Escherichia coli isolated from indigenous individuals in Malaysia [Volume 25, Issue 4, 2022, Pages 468-473]
Viability Knockdown of TRPM7 attenuates apoptosis and inflammation in neonatal necrotizing enterocolitis model cell IEC-6 via modulating TLR4/NF-κB and MEK/ERK pathways [Volume 25, Issue 8, 2022, Pages 947-953]
Vitamin B12 Effect of cyanocobalamin (vitamin B12) on paraquat-induced brain injury in mice [Volume 25, Issue 6, 2022, Pages 745-754]
Vitamin D3 Therapeutic effect of acute and chronic use of different doses of vitamin D3 on seizure responses and cognitive impairments induced by pentylenetetrazole in immature male rats [Volume 25, Issue 1, 2022, Pages 84-95]
Volume of distribution Comparison of pharmacokinetic parameters of ranolazine between diabetic and non-diabetic rats [Volume 25, Issue 7, 2022, Pages 865-870]

Iranian Journal of Basic Medical Sciences

Keyword Index

A

B

C

D

E

F

G

H

I

J

K

L

M

N

O

P

Q

R

S

T

U

V

W

Z