Keyword Index

A

  • A-317491 Neurotropin alleviates rat osteocarcinoma pain via P2X3 receptor activation in the midbrain periaqueductal gray [Volume 24, Issue 10, 2021, Pages 1395-1403]
  • Acetaminophen Evaluation of the protective effect curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats [Volume 24, Issue 6, 2021, Pages 760-766]
  • Acidosis Changes in the expression of the B subunit of vacuolar H+-ATPase, in the hippocampus, following transient forebrain ischemia in gerbils [Volume 24, Issue 11, 2021, Pages 1482-1487]
  • Acinetobacter baumannii Detection of csgA gene in carbapenem-resistant Acinetobacter baumannii strains and targeting with Ocimum sanctum biocompounds [Volume 24, Issue 5, 2021, Pages 690-698]
  • Acinetobacter baumannii Isolation, characterization, and effectiveness of bacteriophage Pɸ-Bw-Ab against XDR Acinetobacter baumannii isolated from nosocomial burn wound infection [Volume 24, Issue 9, 2021, Pages 1254-1263]
  • ACPA The bidirectional effect of prelimbic 5-hydroxytryptamine type-4 (5-HT4) receptors on ACPA-mediated aversive memory impairment in adult male Sprague-Dawley rats [Volume 24, Issue 6, 2021, Pages 726-733]
  • AcrAB-TolC Antibacterial activity of honeys and potential synergism of honeys with antibiotics and alkaloid extract of Sophora alopecuroides plant against antibiotic-resistant Escherichia coli mutant [Volume 24, Issue 5, 2021, Pages 623-628]
  • Acrylamide Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-κB, inflammatory cytokines, iNOS, and oxidative stress [Volume 24, Issue 3, 2021, Pages 312-321]
  • Acrylamide Protective effects of selenium on acrylamide-induced neurotoxicity and hepatotoxicity in rats [Volume 24, Issue 8, 2021, Pages 1041-1049]
  • Actinobacteria Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [Volume 24, Issue 8, 2021, Pages 1058-1068]
  • Acute kidney injury The combination of vitamin D3 and erythropoietin alleviates acute kidney injury induced by ischemia-reperfusion via inhibiting inflammation and apoptosis [Volume 24, Issue 2, 2021, Pages 167-174]
  • Acute kidney injury Sirtuin 3 deficiency promotes acute kidney injury induced by sepsis via mitochondrial dysfunction and apoptosis [Volume 24, Issue 5, 2021, Pages 675-681]
  • Acute lung injury Knockout of PKC θ gene attenuates oleic acid-induced acute lung injury via reduction of inflammation and oxidative stress [Volume 24, Issue 7, 2021, Pages 986-991]
  • Adenosine receptor A2 adenosine receptor contributes to the development of cow’s milk protein allergy via regulating regulatory T cells [Volume 24, Issue 10, 2021, Pages 1380-1387]
  • Adiponectin receptor2 DDP The therapeutic effects of berberine plus sitagliptin in a rat model of fatty liver disease [Volume 24, Issue 4, 2021, Pages 451-459]
  • Adjuvant Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines [Volume 24, Issue 1, 2021, Pages 92-97]
  • Adjuvant Evaluation of Helicobacter pylori OipA protein as a vaccine candidate and propolis as an adjuvant in C57BL/6 mice [Volume 24, Issue 9, 2021, Pages 1220-1230]
  • Adjuvant Recombinant hemagglutinin of swine H1N1 influenza virus expression in the insect cells: Formulation in Montanide ISA71 adjuvant and the potency studies [Volume 24, Issue 11, 2021, Pages 1546-1553]
  • Adrenomedullin Adrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons [Volume 24, Issue 7, 2021, Pages 978-985]
  • Adult T-cell leukemia/-lymphoma (ATLL) Combination of auraptene and arsenic trioxide induces apoptosis and cellular accumulation in the subG1 phase in adult T-cell leukemia cells [Volume 24, Issue 12, 2021, Pages 1643-1649]
  • Aging Diabetes mellitus can cause cardiomyopathy disorders by inducing the aging pathway [Volume 24, Issue 5, 2021, Pages 636-640]
  • Aging Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involved [Volume 24, Issue 6, 2021, Pages 842-850]
  • Aging Atorvastatin modulates the expression of aging-related genes in the brain of aging induced by D-galactose in mice [Volume 24, Issue 10, 2021, Pages 1388-1394]
  • Aging Alzheimer’s disease Electroacupuncture Microbiota Preventive electroacupuncture ameliorates D-galactose-induced Alzheimer’s disease-like inflammation and memory deficits, probably via modulating the microbiota–gut–brain axis [Volume 24, Issue 3, 2021, Pages 341-348]
  • Akt β-LAPachone is renoprotective in streptozotocin-induced diabetic mice via regulating the PI3K/Akt/mTOR signaling pathway [Volume 24, Issue 5, 2021, Pages 650-656]
  • Akt Metformin synergistically increases the anticancer effects of lapatinib through induction of apoptosis and modulation of Akt/AMPK pathway in SK-BR3 breast cancer cell line [Volume 24, Issue 11, 2021, Pages 1529-1537]
  • Albumin Magnetic detection of albuminuria using hematite nanorods synthesized via chemical hydrothermal method [Volume 24, Issue 7, 2021, Pages 962-968]
  • Alginate Immunization against Pseudomonas aeruginosa using Alg-PLGA nano-vaccine [Volume 24, Issue 4, 2021, Pages 476-482]
  • Alkaloid extract Antibacterial activity of honeys and potential synergism of honeys with antibiotics and alkaloid extract of Sophora alopecuroides plant against antibiotic-resistant Escherichia coli mutant [Volume 24, Issue 5, 2021, Pages 623-628]
  • Allergic response A2 adenosine receptor contributes to the development of cow’s milk protein allergy via regulating regulatory T cells [Volume 24, Issue 10, 2021, Pages 1380-1387]
  • Allium cepa L The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review [Volume 24, Issue 1, 2021, Pages 3-16]
  • Allogeneic Allogeneic tumor cell line-based vaccines: A good alternative to autologous and cancer stem cell vaccines in colorectal cancer [Volume 24, Issue 9, 2021, Pages 1231-1239]
  • Alpha L-Carnitine ameliorates the liver by regulating alpha-SMA, iNOS, HSP90, HIF-1alpha, and RIP1 expressions of CCL4-toxic rats [Volume 24, Issue 2, 2021, Pages 184-190]
  • Alpha Alpha-lipoic acid could attenuate the effect of chemerin-induced diabetic nephropathy progression [Volume 24, Issue 8, 2021, Pages 1107-1116]
  • Aluminum chloride Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction [Volume 24, Issue 10, 2021, Pages 1437-1445]
  • Alzheimer’s disease Alzheimer’s disease treatment: The share of herbal medicines [Volume 24, Issue 2, 2021, Pages 123-135]
  • Alzheimer’s disease Favorable effects of dill tablets and Ocimum basilicum L. extract on learning, memory, and hippocampal fatty acid composition in hypercholesterolemic rats [Volume 24, Issue 3, 2021, Pages 300-311]
  • Amino acids Neurochemical effects of sleep deprivation in the hippocampus of the pilocarpine-induced rat model of epilepsy [Volume 24, Issue 1, 2021, Pages 85-91]
  • AMP-activated protein kinases Irisin protects female mice with LPS-induced endometritis through the AMPK/NF-κB pathway [Volume 24, Issue 9, 2021, Pages 1247-1253]
  • Amphetamines Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen [Volume 24, Issue 7, 2021, Pages 856-867]
  • AMPK Metformin synergistically increases the anticancer effects of lapatinib through induction of apoptosis and modulation of Akt/AMPK pathway in SK-BR3 breast cancer cell line [Volume 24, Issue 11, 2021, Pages 1529-1537]
  • Amyloid Aβ Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction [Volume 24, Issue 10, 2021, Pages 1437-1445]
  • Analgesic Gas chromatography-mass spectrometry profiling and analgesic, anti-inflammatory, antipyretic, and antihyperglycemic potentials of Persea americana [Volume 24, Issue 5, 2021, Pages 641-649]
  • Angiogenesis Gene expression of angiogenesis and apoptotic factors in female BALB/c mice with breast cancer after eight weeks of aerobic training [Volume 24, Issue 9, 2021, Pages 1196-1202]
  • Animal model Atorvastatin modulates the expression of aging-related genes in the brain of aging induced by D-galactose in mice [Volume 24, Issue 10, 2021, Pages 1388-1394]
  • Animal model Development and immunohistochemical characterization of patient-derived xenograft models for muscle invasive bladder cancer [Volume 24, Issue 12, 2021, Pages 1650-1655]
  • Animal model Breast neoplasms Immune checkpoints Neoadjuvant chemotherapy Tumor Down-regulation of immune checkpoints by doxorubicin and carboplatin-containing neoadjuvant regimens in a murine breast cancer model [Volume 24, Issue 4, 2021, Pages 537-544]
  • Anti Comparative study of gavage and intraperitoneal administration of gamma-oryzanol in alleviation/attenuation in a rat animal model of renal ischemia/reperfusion-induced injury [Volume 24, Issue 2, 2021, Pages 175-183]
  • Anti Kaempferide improves oxidative stress and inflammation by inhibiting the TLR4/IκBα/NF-κB pathway in obese mice [Volume 24, Issue 4, 2021, Pages 493-498]
  • Antibiotic Evaluation of kinetic stability and anti-staphylococcal activity of recombinant LasA protein produced in Escherichia coli [Volume 24, Issue 6, 2021, Pages 851-855]
  • Antibiotic Iran Meta An updated systematic review and meta-analysis on Mycobacterium tuberculosis antibiotic resistance in Iran (2013-2020) [Volume 24, Issue 4, 2021, Pages 428-436]
  • Antibiotic resistance Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [Volume 24, Issue 2, 2021, Pages 136-142]
  • Antibiotic resistance Antimicrobial resistance patterns, virulence gene profiles, and genetic diversity of Salmonella enterica serotype Enteritidis isolated from patients with gastroenteritis in various Iranian cities [Volume 24, Issue 7, 2021, Pages 914-921]
  • Antibiotic resistance Epidemiology and high incidence of Metallo-β-lactamase and AmpC-β-lactamases in nosocomial Pseudomonas aeruginosa [Volume 24, Issue 10, 2021, Pages 1373-1379]
  • Anticancer Biomedical features of flaxseed against different pathologic situations: A narrative review [Volume 24, Issue 5, 2021, Pages 551-560]
  • Anticancer Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors [Volume 24, Issue 6, 2021, Pages 815-824]
  • Anti-cancer In vivo murine breast cancer targeting by magnetic iron nanoparticles involving L. GG cytoplasmic fraction [Volume 24, Issue 5, 2021, Pages 682-689]
  • Antidepressants Marine algae as emerging therapeutic alternatives for depression: A review [Volume 24, Issue 8, 2021, Pages 997-1013]
  • Antidiabetic Biomedical features of flaxseed against different pathologic situations: A narrative review [Volume 24, Issue 5, 2021, Pages 551-560]
  • Antifungal agent Efficacy of true cinnamon (Cinnamomum verum) leaf essential oil as a therapeutic alternative for Candida biofilm infections [Volume 24, Issue 6, 2021, Pages 787-795]
  • Antihyperglycemic Gas chromatography-mass spectrometry profiling and analgesic, anti-inflammatory, antipyretic, and antihyperglycemic potentials of Persea americana [Volume 24, Issue 5, 2021, Pages 641-649]
  • Antihyperlipidemic Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review [Volume 24, Issue 4, 2021, Pages 420-427]
  • Antihypertensive Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review [Volume 24, Issue 4, 2021, Pages 420-427]
  • Anti-infective agents Time-dependent behavior of the Staphylococcus aureus biofilm following exposure to cold atmospheric pressure plasma [Volume 24, Issue 6, 2021, Pages 744-751]
  • Anti-inflammation Effects of the diphenylheptane extract of Alpinia officinarum rhizomes on ethanol-induced gastric ulcers in mice [Volume 24, Issue 5, 2021, Pages 657-665]
  • Anti-inflammatory Gas chromatography-mass spectrometry profiling and analgesic, anti-inflammatory, antipyretic, and antihyperglycemic potentials of Persea americana [Volume 24, Issue 5, 2021, Pages 641-649]
  • Anti-inflammatory Anti-inflammatory, anti-oxidant, and immunomodulatory activities of the genus Ferula and their constituents: A review [Volume 24, Issue 12, 2021, Pages 1613-1623]
  • Anti-inflammatory Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7) [Volume 24, Issue 12, 2021, Pages 1656-1665]
  • Anti-inflammatory agents The effect of Elettaria cardamomum (cardamom) on the metabolic syndrome: Narrative review [Volume 24, Issue 11, 2021, Pages 1462-1469]
  • Anti-inflammatory - responses M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system [Volume 24, Issue 11, 2021, Pages 1602-1612]
  • Anti-metastatic effect Quercetin synergistically potentiates the anti-metastatic effect of 5-fluorouracil on the MDA-MB-231 breast cancer cell line [Volume 24, Issue 7, 2021, Pages 928-934]
  • Antimicrobial In vitro identification of antimicrobial hemolytic lipopeptide from halotolerant Bacillus by Zymogram, FTIR, and GC mass analysis [Volume 24, Issue 5, 2021, Pages 666-674]
  • Antimicrobial natural Thymoquinone against infectious diseases: Perspectives in recent pandemics and future therapeutics [Volume 24, Issue 8, 2021, Pages 1014-1022]
  • Antioxidant Effects of the diphenylheptane extract of Alpinia officinarum rhizomes on ethanol-induced gastric ulcers in mice [Volume 24, Issue 5, 2021, Pages 657-665]
  • Antioxidant Biomedical features of flaxseed against different pathologic situations: A narrative review [Volume 24, Issue 5, 2021, Pages 551-560]
  • Anti-oxidant Protective effect of cannabinoids on gastric mucosal lesions induced by water immersion restrain stress in rats [Volume 24, Issue 9, 2021, Pages 1182-1189]
  • Anti-oxidant Anti-inflammatory, anti-oxidant, and immunomodulatory activities of the genus Ferula and their constituents: A review [Volume 24, Issue 12, 2021, Pages 1613-1623]
  • Anti-oxidant Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7) [Volume 24, Issue 12, 2021, Pages 1656-1665]
  • Antioxidants Anti-arthritic activity of Ricinus communis L. and Withania somnifera L. extracts in adjuvant-induced arthritic rats via modulating inflammatory mediators and subsiding oxidative stress [Volume 24, Issue 7, 2021, Pages 951-961]
  • Anti-Oxidants The effect of Elettaria cardamomum (cardamom) on the metabolic syndrome: Narrative review [Volume 24, Issue 11, 2021, Pages 1462-1469]
  • Antipyretic Gas chromatography-mass spectrometry profiling and analgesic, anti-inflammatory, antipyretic, and antihyperglycemic potentials of Persea americana [Volume 24, Issue 5, 2021, Pages 641-649]
  • Anti-virulence Growing emergence of drug-resistant Pseudomonas aeruginosa and attenuation of its virulence using quorum sensing inhibitors: A critical review [Volume 24, Issue 6, 2021, Pages 699-719]
  • APOE Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [Volume 24, Issue 12, 2021, Pages 1709-1716]
  • Apoptosis Resveratrol increases the sensitivity of breast cancer MDA-MB-231 cell line to cisplatin by regulating intrinsic apoptosis [Volume 24, Issue 1, 2021, Pages 66-72]
  • Apoptosis Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy [Volume 24, Issue 1, 2021, Pages 38-43]
  • Apoptosis The combination of vitamin D3 and erythropoietin alleviates acute kidney injury induced by ischemia-reperfusion via inhibiting inflammation and apoptosis [Volume 24, Issue 2, 2021, Pages 167-174]
  • Apoptosis Cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion [Volume 24, Issue 2, 2021, Pages 160-166]
  • Apoptosis Protective effects of selenium on electromagnetic field-induced apoptosis, aromatase P450 activity, and leptin receptor expression in rat testis [Volume 24, Issue 3, 2021, Pages 322-330]
  • Apoptosis Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-κB, inflammatory cytokines, iNOS, and oxidative stress [Volume 24, Issue 3, 2021, Pages 312-321]
  • Apoptosis Sirtuin 3 deficiency promotes acute kidney injury induced by sepsis via mitochondrial dysfunction and apoptosis [Volume 24, Issue 5, 2021, Pages 675-681]
  • Apoptosis Cytotoxicity and pro‐apoptosis activity of synthetic 1,3-thiazole incorporated phthalimide derivatives on cancer cells [Volume 24, Issue 5, 2021, Pages 604-614]
  • Apoptosis Quercetin protects islet β‑cells from oxidation-induced apoptosis via Sirt3 in T2DM [Volume 24, Issue 5, 2021, Pages 629-635]
  • Apoptosis Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involved [Volume 24, Issue 6, 2021, Pages 842-850]
  • Apoptosis Cardioprotective effects of co-administration of thymoquinone and ischemic postconditioning in diabetic rats [Volume 24, Issue 7, 2021, Pages 892-899]
  • Apoptosis Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by Boerhavia diffusa root fraction in mdck cell lines [Volume 24, Issue 8, 2021, Pages 1087-1097]
  • Apoptosis Protective effects of selenium on acrylamide-induced neurotoxicity and hepatotoxicity in rats [Volume 24, Issue 8, 2021, Pages 1041-1049]
  • Apoptosis Synergistic anti-cancer effects of silibinin-etoposide combination against human breast carcinoma MCF-7 and MDA-MB-231 cell lines [Volume 24, Issue 9, 2021, Pages 1211-1219]
  • Apoptosis Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase pathways [Volume 24, Issue 9, 2021, Pages 1292-1300]
  • Apoptosis Gene expression of angiogenesis and apoptotic factors in female BALB/c mice with breast cancer after eight weeks of aerobic training [Volume 24, Issue 9, 2021, Pages 1196-1202]
  • Apoptosis Differential expressions of miR-223, miR-424, miR-145, miR-200c, miR-139 in experimental rat chronic pancreatitis model and their relationship between oxidative stress, endoplasmic reticulum stress, and apoptosis [Volume 24, Issue 9, 2021, Pages 1301-1306]
  • Apoptosis Atorvastatin modulates the expression of aging-related genes in the brain of aging induced by D-galactose in mice [Volume 24, Issue 10, 2021, Pages 1388-1394]
  • Apoptosis 4-Hydroxy-3,5-di-tret-butyl cinnamic acid restores the activity of the hippocampal mitochondria in rats under permanent focal cerebral ischemia [Volume 24, Issue 11, 2021, Pages 1590-1601]
  • Apoptosis Zerumbone mediates apoptosis and induces secretion of proinflammatory cytokines in breast carcinoma cell culture [Volume 24, Issue 11, 2021, Pages 1538-1545]
  • Apoptosis In vitro anti-proliferative effect of capecitabine (Xeloda) combined with mocetinostat (MGCD0103) in 4T1 breast cancer cell line by immunoblotting [Volume 24, Issue 11, 2021, Pages 1515-1522]
  • Apoptosis Metformin synergistically increases the anticancer effects of lapatinib through induction of apoptosis and modulation of Akt/AMPK pathway in SK-BR3 breast cancer cell line [Volume 24, Issue 11, 2021, Pages 1529-1537]
  • Apoptosis Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice [Volume 24, Issue 12, 2021, Pages 1695-1701]
  • Apoptosis Vitexin ameliorates GCDC-induced hepatocyte injury through SIRT6 and JAK2/STAT3 pathways [Volume 24, Issue 12, 2021, Pages 1717-1725]
  • Apoptosis Cytotoxicity Lactobacillus casei Recombinant plasmid TP53 and MAP2K1 genes Identification of the effects of acid-resistant Lactobacillus caseimetallopeptidase gene under colon-specific promoter on the colorectal and breast cancer cell lines [Volume 24, Issue 4, 2021, Pages 506-513]
  • Apoptosis Diabetes mellitus Insulin secretion Oxymatrine Potassium channel Voltage Voltage-gated potassium channels are involved in oxymatrine-regulated islet function in rat islet β cells and INS-1 cells [Volume 24, Issue 4, 2021, Pages 460-468]
  • Apoptosis Diabetic cardiomyopathy Exercise Mst1 (STK4) miR Exercise alleviates cardiac remodelling in diabetic cardiomyopathy via the miR-486a-5p-Mst1 pathway [Volume 24, Issue 2, 2021, Pages 150-159]
  • Apoptosis Interleukin Prophylactic effect of intranasal oxytocin on brain damage and neurological disorders in global cerebral ischemia in mice [Volume 24, Issue 1, 2021, Pages 79-84]
  • Apoptosis miR Voluntary exercise improves spermatogenesis and testicular apoptosis in type 2 diabetic rats through alteration in oxidative stress and mir-34a/SIRT1/p53 pathway [Volume 24, Issue 1, 2021, Pages 58-65]
  • ARA-290 Synthesis and evaluation of 99mTc-DOTA-ARA-290 as potential SPECT tracer for targeting cardiac ischemic region [Volume 24, Issue 11, 2021, Pages 1488-1499]
  • ARDS Different microRNAs contribute to the protective effect of mesenchymal stem cell-derived microvesicles in LPS induced acute respiratory distress syndrome [Volume 24, Issue 12, 2021, Pages 1702-1708]
  • Arsenic trioxide (ATO) Combination of auraptene and arsenic trioxide induces apoptosis and cellular accumulation in the subG1 phase in adult T-cell leukemia cells [Volume 24, Issue 12, 2021, Pages 1643-1649]
  • A Seabuckthorn (Hippophae Prevention of cisplatin-induced nausea and vomiting by seabuckthorn (Hippophae rhamnoides L.) seed oil: Insights at the level of orexin-A in rats [Volume 24, Issue 2, 2021, Pages 248-255]
  • Astrocyte Differential pathogenesis of intracerebral and intramuscular inoculation of street rabies virus and CVS-11 strains in a mouse model [Volume 24, Issue 7, 2021, Pages 943-950]
  • AT-101 The SMAC mimetic AT-101 exhibits anti-tumor and anti-metastasis activity in lung adenocarcinoma cells by the IAPs/ caspase-dependent apoptosis and p65-NFƙB cross-talk [Volume 24, Issue 7, 2021, Pages 969-977]
  • Atherosclerosis Curcumin protects human umbilical vein endothelial cells against high oxidized low density lipoprotein-induced lipotoxicity and modulates autophagy [Volume 24, Issue 12, 2021, Pages 1734-1742]
  • ATL HAM/TSP HTLV Planning and management to control and eliminate HTLV-1 infection in Iran [Volume 24, Issue 3, 2021, Pages 264-266]
  • Atorvastatin High Modulatory role of atorvastatin against high-fat diet and zymosan-induced activation of TLR2/NF-ƙB signaling pathway in C57BL/6 mice [Volume 24, Issue 8, 2021, Pages 1023-1032]
  • Aubergine Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review [Volume 24, Issue 4, 2021, Pages 420-427]
  • Auraptene (AUR) Combination of auraptene and arsenic trioxide induces apoptosis and cellular accumulation in the subG1 phase in adult T-cell leukemia cells [Volume 24, Issue 12, 2021, Pages 1643-1649]
  • Autologous Allogeneic tumor cell line-based vaccines: A good alternative to autologous and cancer stem cell vaccines in colorectal cancer [Volume 24, Issue 9, 2021, Pages 1231-1239]
  • Autophagy Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy [Volume 24, Issue 1, 2021, Pages 38-43]
  • Autophagy Diabetes mellitus can cause cardiomyopathy disorders by inducing the aging pathway [Volume 24, Issue 5, 2021, Pages 636-640]
  • Autophagy Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation [Volume 24, Issue 7, 2021, Pages 935-942]
  • Autophagy Ginkgo biloba leaf extract (EGb-761) elicits neuroprotection against cerebral ischemia/reperfusion injury by enhancement of autophagy flux in neurons in the penumbra [Volume 24, Issue 8, 2021, Pages 1138-1145]
  • Autophagy Curcumin protects human umbilical vein endothelial cells against high oxidized low density lipoprotein-induced lipotoxicity and modulates autophagy [Volume 24, Issue 12, 2021, Pages 1734-1742]
  • Avicularin Lettuce-avicularin treatment reverses insulin resistance through stimulation of glycolytic kinases and insulin signaling molecules [Volume 24, Issue 2, 2021, Pages 232-239]
  • Avidity index Fast antibody responses by immuno-targeting and nanotechnology strategies versus HBsAg vaccine [Volume 24, Issue 4, 2021, Pages 545-550]
  • Avocado soybean Chondrogenesis Human adipose Comparison of TGF-β3 and avocado/soybean unsaponifiable on chondrogenesis of human adipose-derived stem cells on poly (lactic-co-glycolic) acid/ hyaluronic acid hybrid scaffold [Volume 24, Issue 1, 2021, Pages 24-29]
  • Axonal inhibitor NgR1 pathway expression in cerebral ischemic Sprague-Dawley rats with cognitive impairment [Volume 24, Issue 6, 2021, Pages 767-775]
  • Azadirachta indica The protective effect of Azadirachta indica (neem) against metabolic syndrome: A review [Volume 24, Issue 3, 2021, Pages 280-292]
  • Azar Association of NOS3-c.894G>T transversion with susceptibility to metabolic syndrome in Azar-cohort population: A case-control study and in silico analysis of the SNP molecular effects [Volume 24, Issue 3, 2021, Pages 408-419]

B

  • B1 Expression of SR-B1 receptor in breast cancer cell lines, MDA-MB-468 and MCF-7: Effect on cell proliferation and apoptosis [Volume 24, Issue 8, 2021, Pages 1069-1077]
  • Bacillus halotolerans In vitro identification of antimicrobial hemolytic lipopeptide from halotolerant Bacillus by Zymogram, FTIR, and GC mass analysis [Volume 24, Issue 5, 2021, Pages 666-674]
  • Bacteriocin Caco Prevalence of bacteriocin genes in Lactobacillus strains isolated from fecal samples of healthy individuals and their inhibitory effect against foodborne pathogens [Volume 24, Issue 8, 2021, Pages 1117-1125]
  • Bacteriophage Isolation, characterization, and effectiveness of bacteriophage Pɸ-Bw-Ab against XDR Acinetobacter baumannii isolated from nosocomial burn wound infection [Volume 24, Issue 9, 2021, Pages 1254-1263]
  • BALB C mouse Humoral immunity Leishmaniasis vaccines Liposomes Phospholipase Sphingomyelin liposome bearing whole Leishmania lysate antigens induce strong Th2 immune response in BALB/c mice [Volume 24, Issue 2, 2021, Pages 222-231]
  • BC BLT Expression of SR-B1 receptor in breast cancer cell lines, MDA-MB-468 and MCF-7: Effect on cell proliferation and apoptosis [Volume 24, Issue 8, 2021, Pages 1069-1077]
  • BDNF The impact of moderate-intensity swimming exercise on learning and memory in aged rats: The role of Sirtuin-1 [Volume 24, Issue 10, 2021, Pages 1413-1420]
  • Behavioral disorders Improved spatial memory, neurobehavioral outcomes, and neuroprotective effect after progesterone administration in ovariectomized rats with traumatic brain injury: Role of RU486 progesterone receptor antagonist [Volume 24, Issue 3, 2021, Pages 349-359]
  • Benzofuran Detection of csgA gene in carbapenem-resistant Acinetobacter baumannii strains and targeting with Ocimum sanctum biocompounds [Volume 24, Issue 5, 2021, Pages 690-698]
  • Beta Subtyping β -lactamase-producing Escherichia coli strains isolated from patients with UTI by MLVA and PFGE methods [Volume 24, Issue 4, 2021, Pages 437-443]
  • Beta-catenin Effects of integrin-linked kinase on protein kinase b, glycogen synthase kinase-3β, and β-catenin molecules in ovarian cancer cells [Volume 24, Issue 11, 2021, Pages 1500-1508]
  • Beta-lactamases Epidemiology and high incidence of Metallo-β-lactamase and AmpC-β-lactamases in nosocomial Pseudomonas aeruginosa [Volume 24, Issue 10, 2021, Pages 1373-1379]
  • Bile duct ligation Combined effect of hydrogen sulfide and mesenchymal stem cells on mitigating liver fibrosis induced by bile duct ligation: Role of anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-fibrotic biomarkers [Volume 24, Issue 12, 2021, Pages 1753-1762]
  • Biofilm Time-dependent behavior of the Staphylococcus aureus biofilm following exposure to cold atmospheric pressure plasma [Volume 24, Issue 6, 2021, Pages 744-751]
  • Biofilm Type1 and 3 fimbriae phenotype and genotype as suitable markers for uropathogenic bacterial pathogenesis via attachment, cell surface hydrophobicity, and biofilm formation in catheter-associated urinary tract infections (CAUTIs) [Volume 24, Issue 8, 2021, Pages 1098-1106]
  • Biofilm inhibitors Growing emergence of drug-resistant Pseudomonas aeruginosa and attenuation of its virulence using quorum sensing inhibitors: A critical review [Volume 24, Issue 6, 2021, Pages 699-719]
  • Biofilms Detection of csgA gene in carbapenem-resistant Acinetobacter baumannii strains and targeting with Ocimum sanctum biocompounds [Volume 24, Issue 5, 2021, Pages 690-698]
  • Biofilms Efficacy of true cinnamon (Cinnamomum verum) leaf essential oil as a therapeutic alternative for Candida biofilm infections [Volume 24, Issue 6, 2021, Pages 787-795]
  • Biofilms Multidrug Interference of Lactobacillus casei with Pseudomonas aeruginosa in the treatment of infected burns in Wistar rats [Volume 24, Issue 2, 2021, Pages 143-149]
  • Biomarker Role of the mesenchymal stem cells derived from adipose tissue in changing the rate of breast cancer cell proliferation and autophagy, in vitro and in vivo [Volume 24, Issue 1, 2021, Pages 98-107]
  • Biomarker Investigating the basis for the antidepressant effects of Gleditsiae spina using an integrated metabolomic strategy [Volume 24, Issue 4, 2021, Pages 524-530]
  • Biomarker Prognostic significance of HOXD4 protein expression in human ovarian cancers [Volume 24, Issue 11, 2021, Pages 1561-1567]
  • Biomedical Biomedical features of flaxseed against different pathologic situations: A narrative review [Volume 24, Issue 5, 2021, Pages 551-560]
  • Boerhavia diffusa Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by Boerhavia diffusa root fraction in mdck cell lines [Volume 24, Issue 8, 2021, Pages 1087-1097]
  • Bone Bosentan, a drug used in the treatment of pulmonary hypertension, can prevent development of osteoporosis [Volume 24, Issue 7, 2021, Pages 922-927]
  • Bone Neurotropin alleviates rat osteocarcinoma pain via P2X3 receptor activation in the midbrain periaqueductal gray [Volume 24, Issue 10, 2021, Pages 1395-1403]
  • Bosentan Bosentan, a drug used in the treatment of pulmonary hypertension, can prevent development of osteoporosis [Volume 24, Issue 7, 2021, Pages 922-927]
  • Bougainvillea spectabilis- flowers Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction [Volume 24, Issue 10, 2021, Pages 1437-1445]
  • B P38 mitogen Alpha-lipoic acid could attenuate the effect of chemerin-induced diabetic nephropathy progression [Volume 24, Issue 8, 2021, Pages 1107-1116]
  • Brain-derived neurotrophic factor Anti-LINGO -1 improved remyelination and neurobehavioral deficit in cuprizone-induced demyelination [Volume 24, Issue 7, 2021, Pages 900-907]
  • Brain edema Evaluation of the protective effect curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats [Volume 24, Issue 6, 2021, Pages 760-766]
  • Brain ischemia Cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion [Volume 24, Issue 2, 2021, Pages 160-166]
  • Breast Zerumbone mediates apoptosis and induces secretion of proinflammatory cytokines in breast carcinoma cell culture [Volume 24, Issue 11, 2021, Pages 1538-1545]
  • Breast Cancer Resveratrol increases the sensitivity of breast cancer MDA-MB-231 cell line to cisplatin by regulating intrinsic apoptosis [Volume 24, Issue 1, 2021, Pages 66-72]
  • Breast Cancer Quercetin synergistically potentiates the anti-metastatic effect of 5-fluorouracil on the MDA-MB-231 breast cancer cell line [Volume 24, Issue 7, 2021, Pages 928-934]
  • Breast Cancer Synergistic anti-cancer effects of silibinin-etoposide combination against human breast carcinoma MCF-7 and MDA-MB-231 cell lines [Volume 24, Issue 9, 2021, Pages 1211-1219]
  • Breast Cancer Gene expression of angiogenesis and apoptotic factors in female BALB/c mice with breast cancer after eight weeks of aerobic training [Volume 24, Issue 9, 2021, Pages 1196-1202]
  • Breast Cancer Development of camelid monoclonal nanobody against SLC39A6 zinc transporter protein [Volume 24, Issue 12, 2021, Pages 1726-1733]
  • Breast neoplasms In vitro anti-proliferative effect of capecitabine (Xeloda) combined with mocetinostat (MGCD0103) in 4T1 breast cancer cell line by immunoblotting [Volume 24, Issue 11, 2021, Pages 1515-1522]
  • Bromelain Evaluation of debridement effects of bromelain-loaded sodium alginate nanoparticles incorporated into chitosan hydrogel in animal models [Volume 24, Issue 10, 2021, Pages 1404-1412]
  • Brucella abortus RB51 Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines [Volume 24, Issue 1, 2021, Pages 92-97]
  • Brucella melitensis Epitope mapping MALDI Evaluation of the designed multi-epitope protein of Brucella melitensis in guinea pigs [Volume 24, Issue 6, 2021, Pages 833-841]
  • Burns Isolation, characterization, and effectiveness of bacteriophage Pɸ-Bw-Ab against XDR Acinetobacter baumannii isolated from nosocomial burn wound infection [Volume 24, Issue 9, 2021, Pages 1254-1263]

C

  • Calf thymus DNA Impact of linker histone in the formation of ambochlorin-calf thymus DNA complex: Multi-spectroscopic, stopped-flow, and molecular modeling approaches [Volume 24, Issue 11, 2021, Pages 1568-1582]
  • Cancer cells Cytotoxicity and pro‐apoptosis activity of synthetic 1,3-thiazole incorporated phthalimide derivatives on cancer cells [Volume 24, Issue 5, 2021, Pages 604-614]
  • Cancer Stem cell PANC-1 cancer stem-like cell death with silybin encapsulated in polymersomes and deregulation of stemness-related miRNAs and their potential targets [Volume 24, Issue 4, 2021, Pages 514-523]
  • Cancer Stem cell Allogeneic tumor cell line-based vaccines: A good alternative to autologous and cancer stem cell vaccines in colorectal cancer [Volume 24, Issue 9, 2021, Pages 1231-1239]
  • Cancer therapy Mesenchymal stem cells as professional actors in gastrointestinal cancer therapy: From Naïve to genetically modified [Volume 24, Issue 5, 2021, Pages 561-576]
  • Cancer therapy CPPs Doxorubicin Multi Effects of self-assembled cell-penetrating peptides and their nano-complexes on ABCB1 expression and activity [Volume 24, Issue 3, 2021, Pages 383-390]
  • Candida spp Efficacy of true cinnamon (Cinnamomum verum) leaf essential oil as a therapeutic alternative for Candida biofilm infections [Volume 24, Issue 6, 2021, Pages 787-795]
  • Cannabinoid receptor Protective effect of cannabinoids on gastric mucosal lesions induced by water immersion restrain stress in rats [Volume 24, Issue 9, 2021, Pages 1182-1189]
  • Capecitabine In vitro anti-proliferative effect of capecitabine (Xeloda) combined with mocetinostat (MGCD0103) in 4T1 breast cancer cell line by immunoblotting [Volume 24, Issue 11, 2021, Pages 1515-1522]
  • Carcinogenesis Mesenchymal stem cells in cancer therapy; the art of harnessing a foe to a friend [Volume 24, Issue 10, 2021, Pages 1307-1323]
  • Carcinoma Role of the mesenchymal stem cells derived from adipose tissue in changing the rate of breast cancer cell proliferation and autophagy, in vitro and in vivo [Volume 24, Issue 1, 2021, Pages 98-107]
  • Cardiac Diabetes mellitus can cause cardiomyopathy disorders by inducing the aging pathway [Volume 24, Issue 5, 2021, Pages 636-640]
  • Cardiomyopathy Effect of pantoprazole on I-R -induced myocardial injury in diabetic rats targeting inflammatory cytokine release and oxidative stress [Volume 24, Issue 5, 2021, Pages 615-622]
  • Cardiomyopathy Diabetes mellitus can cause cardiomyopathy disorders by inducing the aging pathway [Volume 24, Issue 5, 2021, Pages 636-640]
  • Cardiovascular Therapy with new generation of biodegradable and bioconjugate 3D printed artificial gastrointestinal lumen [Volume 24, Issue 3, 2021, Pages 391-399]
  • Cardiovascular Disease Liraglutide ameliorates myocardial damage in experimental diabetic rats by inhibiting pyroptosis via Sirt1/AMPK signaling [Volume 24, Issue 10, 2021, Pages 1358-1365]
  • Cardiovascular system Role of the glutamatergic system of ventrolateral periaqueductal gray (vlPAG) in the cardiovascular responses in normal and hemorrhagic conditions in rats [Volume 24, Issue 5, 2021, Pages 586-594]
  • Cas9 Induced tolerance PD Use of dual-transfection for programmed death cell protein 1 disruption mediated by CRISPR-Cas9 in human peripheral blood mononuclear cells [Volume 24, Issue 1, 2021, Pages 44-50]
  • CASP1 Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [Volume 24, Issue 10, 2021, Pages 1421-1427]
  • Caspase3 Mesenchymal stem cells promote caspase-3 expression of SH-SY5Y neuroblastoma cells via reducing telomerase activity and telomere length [Volume 24, Issue 11, 2021, Pages 1583-1589]
  • Caspase 3 Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by Boerhavia diffusa root fraction in mdck cell lines [Volume 24, Issue 8, 2021, Pages 1087-1097]
  • Caspase-3 Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation [Volume 24, Issue 7, 2021, Pages 935-942]
  • Caspases The SMAC mimetic AT-101 exhibits anti-tumor and anti-metastasis activity in lung adenocarcinoma cells by the IAPs/ caspase-dependent apoptosis and p65-NFƙB cross-talk [Volume 24, Issue 7, 2021, Pages 969-977]
  • Catheterization Type1 and 3 fimbriae phenotype and genotype as suitable markers for uropathogenic bacterial pathogenesis via attachment, cell surface hydrophobicity, and biofilm formation in catheter-associated urinary tract infections (CAUTIs) [Volume 24, Issue 8, 2021, Pages 1098-1106]
  • CD25 Daclizumab IL Designing and generating a single-chain fragment variable (scFv) antibody against IL2Rα (CD25): An in silico and in vitro study [Volume 24, Issue 3, 2021, Pages 360-368]
  • Cell cycle Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by Boerhavia diffusa root fraction in mdck cell lines [Volume 24, Issue 8, 2021, Pages 1087-1097]
  • Cell death Changes in the expression of the B subunit of vacuolar H+-ATPase, in the hippocampus, following transient forebrain ischemia in gerbils [Volume 24, Issue 11, 2021, Pages 1482-1487]
  • Cell differentiation LILRA3 is related to monocyte-derived dendritic cell maturation and activation [Volume 24, Issue 2, 2021, Pages 196-202]
  • Cell growth Role of the mesenchymal stem cells derived from adipose tissue in changing the rate of breast cancer cell proliferation and autophagy, in vitro and in vivo [Volume 24, Issue 1, 2021, Pages 98-107]
  • Cell therapy Role of the mesenchymal stem cells derived from adipose tissue in changing the rate of breast cancer cell proliferation and autophagy, in vitro and in vivo [Volume 24, Issue 1, 2021, Pages 98-107]
  • Cell therapy c-kit+ cells offer hopes in ameliorating asthmatic pathologies via regulation of miRNA-133 and -126 [Volume 24, Issue 3, 2021, Pages 369-376]
  • Cell therapy Checkpoint protein CRISPR Use of dual-transfection for programmed death cell protein 1 disruption mediated by CRISPR-Cas9 in human peripheral blood mononuclear cells [Volume 24, Issue 1, 2021, Pages 44-50]
  • Cellular immunity CpG oligodeoxynucleotides DNA vaccine HIV Immunogenicity evaluation of the HIV-1 Tat containing polyepitope DNA vaccine adjuvanted with CpG-ODNs in mice [Volume 24, Issue 3, 2021, Pages 377-382]
  • Cellular senescence In search of elixir: Pharmacological agents against stem cell senescence [Volume 24, Issue 7, 2021, Pages 868-880]
  • Cerebral ischemia NgR1 pathway expression in cerebral ischemic Sprague-Dawley rats with cognitive impairment [Volume 24, Issue 6, 2021, Pages 767-775]
  • Cerebral ischemia 4-Hydroxy-3,5-di-tret-butyl cinnamic acid restores the activity of the hippocampal mitochondria in rats under permanent focal cerebral ischemia [Volume 24, Issue 11, 2021, Pages 1590-1601]
  • Cervical Cancer Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines [Volume 24, Issue 1, 2021, Pages 92-97]
  • Cervical Cancer Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression [Volume 24, Issue 11, 2021, Pages 1470-1481]
  • CFTR gene Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells [Volume 24, Issue 1, 2021, Pages 73-78]
  • Chemokine receptor Inhibitory effects of tolerogenic probiotics on migratory potential of lupus patient-derived DCs [Volume 24, Issue 11, 2021, Pages 1509-1514]
  • Chitin microparticles Intranasal administration of immunogenic poly-epitope from influenza H1N1 and H3N2 viruses adjuvanted with chitin and chitosan microparticles in BALB/c mice [Volume 24, Issue 8, 2021, Pages 1126-1137]
  • Chitosan Evaluation of debridement effects of bromelain-loaded sodium alginate nanoparticles incorporated into chitosan hydrogel in animal models [Volume 24, Issue 10, 2021, Pages 1404-1412]
  • Chitosan microparticles Intranasal administration of immunogenic poly-epitope from influenza H1N1 and H3N2 viruses adjuvanted with chitin and chitosan microparticles in BALB/c mice [Volume 24, Issue 8, 2021, Pages 1126-1137]
  • Cholecalciferol The combination of vitamin D3 and erythropoietin alleviates acute kidney injury induced by ischemia-reperfusion via inhibiting inflammation and apoptosis [Volume 24, Issue 2, 2021, Pages 167-174]
  • Chronic Pancreatitis Differential expressions of miR-223, miR-424, miR-145, miR-200c, miR-139 in experimental rat chronic pancreatitis model and their relationship between oxidative stress, endoplasmic reticulum stress, and apoptosis [Volume 24, Issue 9, 2021, Pages 1301-1306]
  • Cinnamic acid derivatives 4-Hydroxy-3,5-di-tret-butyl cinnamic acid restores the activity of the hippocampal mitochondria in rats under permanent focal cerebral ischemia [Volume 24, Issue 11, 2021, Pages 1590-1601]
  • Cinnamomum verum Essential oil Efficacy of true cinnamon (Cinnamomum verum) leaf essential oil as a therapeutic alternative for Candida biofilm infections [Volume 24, Issue 6, 2021, Pages 787-795]
  • Circular dichroism Impact of linker histone in the formation of ambochlorin-calf thymus DNA complex: Multi-spectroscopic, stopped-flow, and molecular modeling approaches [Volume 24, Issue 11, 2021, Pages 1568-1582]
  • Cisplatin Resveratrol increases the sensitivity of breast cancer MDA-MB-231 cell line to cisplatin by regulating intrinsic apoptosis [Volume 24, Issue 1, 2021, Pages 66-72]
  • Cisplatin Prevention of cisplatin-induced nausea and vomiting by seabuckthorn (Hippophae rhamnoides L.) seed oil: Insights at the level of orexin-A in rats [Volume 24, Issue 2, 2021, Pages 248-255]
  • Coating Excipients Liqui Rapid releasing naproxen Liqui-Pellet using effervescent agent and neusilin US2 [Volume 24, Issue 1, 2021, Pages 108-115]
  • Cobaltous chloride G-CSF augments the neuroprotective effect of conditioned medium of dental pulp stem cells against hypoxic neural injury in SH-SY5Y cells [Volume 24, Issue 12, 2021, Pages 1743-1752]
  • Cocaine Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen [Volume 24, Issue 7, 2021, Pages 856-867]
  • Cognitive impairment NgR1 pathway expression in cerebral ischemic Sprague-Dawley rats with cognitive impairment [Volume 24, Issue 6, 2021, Pages 767-775]
  • Colitis Pretreatment with licochalcone a enhances therapeutic activity of rat bone marrow mesenchymal stem cells in animal models of colitis [Volume 24, Issue 8, 2021, Pages 1050-1057]
  • Colonic neoplasms Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase pathways [Volume 24, Issue 9, 2021, Pages 1292-1300]
  • Colorectal cancer MKK4 variants rs3826392 and rs3809728 are associated with susceptibility and clinicopathological features in colorectal cancer patients [Volume 24, Issue 8, 2021, Pages 1033-1040]
  • Colorectal cancer Allogeneic tumor cell line-based vaccines: A good alternative to autologous and cancer stem cell vaccines in colorectal cancer [Volume 24, Issue 9, 2021, Pages 1231-1239]
  • Colorectal cancer Dermatopontin Real Non-collagenous extracellular matrix protein dermatopontin may play a role as another component of transforming growth factor-β signaling pathway in colon carcinogenesis [Volume 24, Issue 4, 2021, Pages 444-450]
  • Colorectal neoplasms Epithelial NLRP3-inflammasome activation is associated with epithelial-mesenchymal transition and progression of colorectal cancer [Volume 24, Issue 4, 2021, Pages 483-492]
  • Combined therapy Resveratrol increases the sensitivity of breast cancer MDA-MB-231 cell line to cisplatin by regulating intrinsic apoptosis [Volume 24, Issue 1, 2021, Pages 66-72]
  • Complementary Medicine Marine algae as emerging therapeutic alternatives for depression: A review [Volume 24, Issue 8, 2021, Pages 997-1013]
  • Conditioned medium Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase pathways [Volume 24, Issue 9, 2021, Pages 1292-1300]
  • Convicilin protein Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease [Volume 24, Issue 6, 2021, Pages 734-743]
  • Copolymer Sustained release of linezolid in ocular insert based on lipophilic modified structure of sodium alginate [Volume 24, Issue 3, 2021, Pages 331-340]
  • Corilagin Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7) [Volume 24, Issue 12, 2021, Pages 1656-1665]
  • Coumarins Anti-inflammatory, anti-oxidant, and immunomodulatory activities of the genus Ferula and their constituents: A review [Volume 24, Issue 12, 2021, Pages 1613-1623]
  • CoV Thymoquinone Thymoquinone against infectious diseases: Perspectives in recent pandemics and future therapeutics [Volume 24, Issue 8, 2021, Pages 1014-1022]
  • Cow’s milk protein allergy A2 adenosine receptor contributes to the development of cow’s milk protein allergy via regulating regulatory T cells [Volume 24, Issue 10, 2021, Pages 1380-1387]
  • CREB The impact of moderate-intensity swimming exercise on learning and memory in aged rats: The role of Sirtuin-1 [Volume 24, Issue 10, 2021, Pages 1413-1420]
  • CRISPR Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells [Volume 24, Issue 1, 2021, Pages 73-78]
  • CRISPR/Cas9 Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC) [Volume 24, Issue 8, 2021, Pages 1153-1158]
  • Crocin Ameliorative effects of crocin on the inflammation and oxidative stress-induced kidney damages by experimental periodontitis in rat [Volume 24, Issue 6, 2021, Pages 825-832]
  • Crocus sativus Alzheimer’s disease treatment: The share of herbal medicines [Volume 24, Issue 2, 2021, Pages 123-135]
  • Cross The dry powder formulation of mixed cross-linked dextran microspheres and tetanus toxoid-loaded trimethyl chitosan nanospheres as a potent adjuvant for nasal delivery system [Volume 24, Issue 1, 2021, Pages 116-122]
  • CTLA-4 antigen Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4) [Volume 24, Issue 9, 2021, Pages 1264-1271]
  • Cuprizone Anti-LINGO -1 improved remyelination and neurobehavioral deficit in cuprizone-induced demyelination [Volume 24, Issue 7, 2021, Pages 900-907]
  • Curcumin Evaluation of the protective effect curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats [Volume 24, Issue 6, 2021, Pages 760-766]
  • Curcumin Curcumin protects human umbilical vein endothelial cells against high oxidized low density lipoprotein-induced lipotoxicity and modulates autophagy [Volume 24, Issue 12, 2021, Pages 1734-1742]
  • CXC chemokine receptor 4 Therapeutic potential of mesenchymal stem cells for peripheral artery disease in a rat model of hindlimb ischemia [Volume 24, Issue 6, 2021, Pages 805-814]
  • CXCR4 Pretreatment with licochalcone a enhances therapeutic activity of rat bone marrow mesenchymal stem cells in animal models of colitis [Volume 24, Issue 8, 2021, Pages 1050-1057]
  • Cyanocobalamin Cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion [Volume 24, Issue 2, 2021, Pages 160-166]
  • Cyclic AMP Adrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons [Volume 24, Issue 7, 2021, Pages 978-985]
  • Cyclooxygenase-2 Evaluation of Interleukin-32 and cyclooxygenase-2 expression in HAM/TSP patients and HTLV-1 asymptomatic carriers [Volume 24, Issue 7, 2021, Pages 992-996]
  • Cystic fibrosis Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells [Volume 24, Issue 1, 2021, Pages 73-78]
  • Cytokine Immunization against Pseudomonas aeruginosa using Alg-PLGA nano-vaccine [Volume 24, Issue 4, 2021, Pages 476-482]
  • Cytokine A study of the transformation of umbilical cord mesenchymal stem cells by interferon-gamma [Volume 24, Issue 9, 2021, Pages 1203-1210]
  • Cytokine Zerumbone mediates apoptosis and induces secretion of proinflammatory cytokines in breast carcinoma cell culture [Volume 24, Issue 11, 2021, Pages 1538-1545]
  • Cytokines Neurochemical effects of sleep deprivation in the hippocampus of the pilocarpine-induced rat model of epilepsy [Volume 24, Issue 1, 2021, Pages 85-91]
  • Cytokines Respiratory syncytial virus infection of microglia exacerbates SH-SY5Y neuronal cell injury by inducing the secretion of inflammatory cytokines: A Transwell in vitro study [Volume 24, Issue 2, 2021, Pages 213-221]
  • Cytokines Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-κB, inflammatory cytokines, iNOS, and oxidative stress [Volume 24, Issue 3, 2021, Pages 312-321]
  • Cytokines Dopaminergic agonist pramipexole improves memory and increases IL-10 production in LPS-challenged rats [Volume 24, Issue 5, 2021, Pages 577-585]
  • Cytokines Effects of synthetic silymarin-PLGA nanoparticles on M2 polarization and inflammatory cytokines in LPS-treated murine peritoneal macrophages [Volume 24, Issue 10, 2021, Pages 1446-1454]
  • Cytotoxicity Cytotoxicity and pro‐apoptosis activity of synthetic 1,3-thiazole incorporated phthalimide derivatives on cancer cells [Volume 24, Issue 5, 2021, Pages 604-614]

D

  • Dactinomycin Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [Volume 24, Issue 8, 2021, Pages 1058-1068]
  • DDR2 gene In silico Sanger sequencing Splice Identification of a novel homozygous mutation in the DDR2 gene from a patient with spondylo-meta-epiphyseal dysplasia by whole exome sequencing [Volume 24, Issue 2, 2021, Pages 191-195]
  • Debridement Evaluation of debridement effects of bromelain-loaded sodium alginate nanoparticles incorporated into chitosan hydrogel in animal models [Volume 24, Issue 10, 2021, Pages 1404-1412]
  • Decellularization Formation of organoid-like structures in the decellularized rat testis [Volume 24, Issue 11, 2021, Pages 1523-1528]
  • Dendritic cell LILRA3 is related to monocyte-derived dendritic cell maturation and activation [Volume 24, Issue 2, 2021, Pages 196-202]
  • Dental pulp Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase pathways [Volume 24, Issue 9, 2021, Pages 1292-1300]
  • Dentate gyrus Spatial and temporal changes in the PGE2 EP2 receptor in mice hippocampi during postnatal development and its relationship with cyclooxygenase-2 [Volume 24, Issue 7, 2021, Pages 908-913]
  • Depression Investigating the basis for the antidepressant effects of Gleditsiae spina using an integrated metabolomic strategy [Volume 24, Issue 4, 2021, Pages 524-530]
  • Depression Marine algae as emerging therapeutic alternatives for depression: A review [Volume 24, Issue 8, 2021, Pages 997-1013]
  • Detorsion Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation [Volume 24, Issue 7, 2021, Pages 935-942]
  • Developmental disabilities PLA2G6 gene mutation and infantile neuroaxonal degeneration; report of three cases from Iran [Volume 24, Issue 9, 2021, Pages 1190-1195]
  • Diabetes The protective effect of Azadirachta indica (neem) against metabolic syndrome: A review [Volume 24, Issue 3, 2021, Pages 280-292]
  • Diabetes Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review [Volume 24, Issue 4, 2021, Pages 420-427]
  • Diabetes Cardioprotective effects of co-administration of thymoquinone and ischemic postconditioning in diabetic rats [Volume 24, Issue 7, 2021, Pages 892-899]
  • Diabetes Green tea and metabolic syndrome: A 10-year research update review [Volume 24, Issue 9, 2021, Pages 1159-1172]
  • Diabetes Voluntary exercise could reduce sperm malformations by improving hypothalamus-hypophysis-gonadal axis and kisspeptin/leptin signaling in type 2 diabetic rats [Volume 24, Issue 12, 2021, Pages 1624-1631]
  • Diabetes Mellitus The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review [Volume 24, Issue 1, 2021, Pages 3-16]
  • Diabetes Mellitus Effect of pantoprazole on I-R -induced myocardial injury in diabetic rats targeting inflammatory cytokine release and oxidative stress [Volume 24, Issue 5, 2021, Pages 615-622]
  • Diabetes Mellitus Diabetes mellitus can cause cardiomyopathy disorders by inducing the aging pathway [Volume 24, Issue 5, 2021, Pages 636-640]
  • Diabetes Mellitus Liraglutide ameliorates myocardial damage in experimental diabetic rats by inhibiting pyroptosis via Sirt1/AMPK signaling [Volume 24, Issue 10, 2021, Pages 1358-1365]
  • Diabetic nephropathy β-LAPachone is renoprotective in streptozotocin-induced diabetic mice via regulating the PI3K/Akt/mTOR signaling pathway [Volume 24, Issue 5, 2021, Pages 650-656]
  • Diabetic retinopathy MicroRNAs may provide new strategies in the treatment and diagnosis of diabetic retinopathy: Importance of VEGF [Volume 24, Issue 3, 2021, Pages 267-279]
  • Diabetic retinopathy Interaction of miR-146a-5p with oxidative stress and inflammation in complications of type 2 diabetes mellitus in male rats: antioxidant and anti-inflammatory protection strategies in type 2 diabetic retinopathy [Volume 24, Issue 8, 2021, Pages 1078-1086]
  • Differentiation A study of the transformation of umbilical cord mesenchymal stem cells by interferon-gamma [Volume 24, Issue 9, 2021, Pages 1203-1210]
  • Dill Favorable effects of dill tablets and Ocimum basilicum L. extract on learning, memory, and hippocampal fatty acid composition in hypercholesterolemic rats [Volume 24, Issue 3, 2021, Pages 300-311]
  • Dimensional gel Evaluation of the designed multi-epitope protein of Brucella melitensis in guinea pigs [Volume 24, Issue 6, 2021, Pages 833-841]
  • Dimethenamid Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [Volume 24, Issue 8, 2021, Pages 1058-1068]
  • Dimethylamino-arthenolide Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [Volume 24, Issue 10, 2021, Pages 1421-1427]
  • Diphenylheptane Effects of the diphenylheptane extract of Alpinia officinarum rhizomes on ethanol-induced gastric ulcers in mice [Volume 24, Issue 5, 2021, Pages 657-665]
  • DMD Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC) [Volume 24, Issue 8, 2021, Pages 1153-1158]
  • DNA vaccine DNA vaccine containing Flagellin A gene induces significant immune responses against Helicobacter pylori infection: An in vivo study [Volume 24, Issue 6, 2021, Pages 796-804]
  • DNA Vaccines Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines [Volume 24, Issue 1, 2021, Pages 92-97]
  • Dopamine Neuroprotective effects of Wharton’s jelly-derived mesenchymal stem cells on motor deficits due to Parkinson’s disease [Volume 24, Issue 9, 2021, Pages 1173-1181]
  • Drug Delivery In vivo murine breast cancer targeting by magnetic iron nanoparticles involving L. GG cytoplasmic fraction [Volume 24, Issue 5, 2021, Pages 682-689]
  • Drug resistance Detection of csgA gene in carbapenem-resistant Acinetobacter baumannii strains and targeting with Ocimum sanctum biocompounds [Volume 24, Issue 5, 2021, Pages 690-698]
  • Drug resistance Rifampicin-resistant tuberculosis in Iran: A systematic review and meta-analysis [Volume 24, Issue 6, 2021, Pages 720-725]
  • Drug resistance Isolation, characterization, and effectiveness of bacteriophage Pɸ-Bw-Ab against XDR Acinetobacter baumannii isolated from nosocomial burn wound infection [Volume 24, Issue 9, 2021, Pages 1254-1263]
  • Drug synergism Synergistic anti-cancer effects of silibinin-etoposide combination against human breast carcinoma MCF-7 and MDA-MB-231 cell lines [Volume 24, Issue 9, 2021, Pages 1211-1219]
  • Drug synergism In vitro anti-proliferative effect of capecitabine (Xeloda) combined with mocetinostat (MGCD0103) in 4T1 breast cancer cell line by immunoblotting [Volume 24, Issue 11, 2021, Pages 1515-1522]
  • Drug synergism Metformin synergistically increases the anticancer effects of lapatinib through induction of apoptosis and modulation of Akt/AMPK pathway in SK-BR3 breast cancer cell line [Volume 24, Issue 11, 2021, Pages 1529-1537]
  • Dust Gallic acid NAFLD Nrf2 Rat TNF Gallic acid treats dust-induced NAFLD in rats by improving the liver’s anti-oxidant capacity and inhibiting ROS/NFκβ/TNFα inflammatory pathway [Volume 24, Issue 2, 2021, Pages 240-247]
  • Dyslipidemia The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review [Volume 24, Issue 1, 2021, Pages 3-16]
  • Dyslipidemia Green tea and metabolic syndrome: A 10-year research update review [Volume 24, Issue 9, 2021, Pages 1159-1172]
  • Dystrophin Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC) [Volume 24, Issue 8, 2021, Pages 1153-1158]

E

  • EDDA Effect of using different co-ligands during 99mTc-labeling of J18 peptide on SK-MES-1 cell binding and tumor targeting [Volume 24, Issue 9, 2021, Pages 1240-1246]
  • Eggplant Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review [Volume 24, Issue 4, 2021, Pages 420-427]
  • Electroacupuncture Transient receptor potential V1 modulates neuroinflammation in Parkinson’s disease dementia: Molecular implications for electroacupuncture and rivastigmine [Volume 24, Issue 10, 2021, Pages 1336-1345]
  • Electromagnetic Field Description of the calf thymus DNA-malathion complex behavior by multi-spectroscopic and molecular modeling techniques: EMF at low and high frequency approaches [Volume 24, Issue 10, 2021, Pages 1346-1357]
  • Electromagnetic Radiation Protective effects of selenium on electromagnetic field-induced apoptosis, aromatase P450 activity, and leptin receptor expression in rat testis [Volume 24, Issue 3, 2021, Pages 322-330]
  • Electrospun nanofiber Propranolol-loaded electrospun nanofibrous wound dressing: From fabrication and characterization to preliminary wound healing evaluation [Volume 24, Issue 9, 2021, Pages 1279-1291]
  • Elettaria cardamomum The effect of Elettaria cardamomum (cardamom) on the metabolic syndrome: Narrative review [Volume 24, Issue 11, 2021, Pages 1462-1469]
  • Embolic stroke Ischemic post-conditioning is neuroprotective even at delayed tPA administration after embolic stroke in female rats [Volume 24, Issue 12, 2021, Pages 1676-1682]
  • Endometritis Irisin protects female mice with LPS-induced endometritis through the AMPK/NF-κB pathway [Volume 24, Issue 9, 2021, Pages 1247-1253]
  • Endoplasmic reticulum- stress Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice [Volume 24, Issue 12, 2021, Pages 1695-1701]
  • Endothelial cells Curcumin protects human umbilical vein endothelial cells against high oxidized low density lipoprotein-induced lipotoxicity and modulates autophagy [Volume 24, Issue 12, 2021, Pages 1734-1742]
  • Endothelial progenitor cells In search of elixir: Pharmacological agents against stem cell senescence [Volume 24, Issue 7, 2021, Pages 868-880]
  • Endothelin Bosentan, a drug used in the treatment of pulmonary hypertension, can prevent development of osteoporosis [Volume 24, Issue 7, 2021, Pages 922-927]
  • Endothelin A receptor Bosentan, a drug used in the treatment of pulmonary hypertension, can prevent development of osteoporosis [Volume 24, Issue 7, 2021, Pages 922-927]
  • Enhancement Ginkgo biloba leaf extract (EGb-761) elicits neuroprotection against cerebral ischemia/reperfusion injury by enhancement of autophagy flux in neurons in the penumbra [Volume 24, Issue 8, 2021, Pages 1138-1145]
  • Enhancers Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression [Volume 24, Issue 11, 2021, Pages 1470-1481]
  • Epilepsy Neurochemical effects of sleep deprivation in the hippocampus of the pilocarpine-induced rat model of epilepsy [Volume 24, Issue 1, 2021, Pages 85-91]
  • Epithelial ovarian cancer Effects of integrin-linked kinase on protein kinase b, glycogen synthase kinase-3β, and β-catenin molecules in ovarian cancer cells [Volume 24, Issue 11, 2021, Pages 1500-1508]
  • Epitope design Novel single-chain antibodies against highly conserved epitopes in the hemagglutinin of influenza A viruses: Promising agents for universal therapies [Volume 24, Issue 1, 2021, Pages 17-23]
  • ERK/ERK The therapeutic effects of berberine plus sitagliptin in a rat model of fatty liver disease [Volume 24, Issue 4, 2021, Pages 451-459]
  • Erythropoietin The combination of vitamin D3 and erythropoietin alleviates acute kidney injury induced by ischemia-reperfusion via inhibiting inflammation and apoptosis [Volume 24, Issue 2, 2021, Pages 167-174]
  • Erythropoietin (EPO) Synthesis and evaluation of 99mTc-DOTA-ARA-290 as potential SPECT tracer for targeting cardiac ischemic region [Volume 24, Issue 11, 2021, Pages 1488-1499]
  • ESBL Correlation between antibiotic resistance and phylogenetic types among multidrug-resistant Escherichia coli isolated from urinary tract infections [Volume 24, Issue 3, 2021, Pages 400-407]
  • Escherichia coli Correlation between antibiotic resistance and phylogenetic types among multidrug-resistant Escherichia coli isolated from urinary tract infections [Volume 24, Issue 3, 2021, Pages 400-407]
  • Escherichia coli Antibacterial activity of honeys and potential synergism of honeys with antibiotics and alkaloid extract of Sophora alopecuroides plant against antibiotic-resistant Escherichia coli mutant [Volume 24, Issue 5, 2021, Pages 623-628]
  • Estradiol benzoate Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosis [Volume 24, Issue 2, 2021, Pages 256-263]
  • Ethanol Hepatic steatosis Myeloperoxidase Protocatechuic acid S Combination of s-methyl cysteine and protocatechuic acid provided greater lipid-lowering and anti-inflammatory effects in mice liver against chronic alcohol consumption [Volume 24, Issue 8, 2021, Pages 1146-1152]
  • Etoposide Synergistic anti-cancer effects of silibinin-etoposide combination against human breast carcinoma MCF-7 and MDA-MB-231 cell lines [Volume 24, Issue 9, 2021, Pages 1211-1219]
  • Eugenol Detection of csgA gene in carbapenem-resistant Acinetobacter baumannii strains and targeting with Ocimum sanctum biocompounds [Volume 24, Issue 5, 2021, Pages 690-698]
  • Exotoxin A Preparation and evaluation of the exotoxin A nano-gold conjugate as a vaccine candidate for Pseudomonas aeruginosa infections [Volume 24, Issue 10, 2021, Pages 1366-1372]
  • Expression Identification of the effects of acid-resistant Lactobacillus caseimetallopeptidase gene under colon-specific promoter on the colorectal and breast cancer cell lines [Volume 24, Issue 4, 2021, Pages 506-513]
  • Extracellular matrix Formation of organoid-like structures in the decellularized rat testis [Volume 24, Issue 11, 2021, Pages 1523-1528]
  • Extracellular polymeric substances Time-dependent behavior of the Staphylococcus aureus biofilm following exposure to cold atmospheric pressure plasma [Volume 24, Issue 6, 2021, Pages 744-751]

F

  • Familial Mediterranean fever Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [Volume 24, Issue 10, 2021, Pages 1421-1427]
  • Fear extinction In vivo blockade of 5HT3 receptors in the infralimbic medial prefrontal cortex enhances fear extinction in a rat model of PTSD [Volume 24, Issue 6, 2021, Pages 776-786]
  • Female rat Ischemic post-conditioning is neuroprotective even at delayed tPA administration after embolic stroke in female rats [Volume 24, Issue 12, 2021, Pages 1676-1682]
  • Ferula Anti-inflammatory, anti-oxidant, and immunomodulatory activities of the genus Ferula and their constituents: A review [Volume 24, Issue 12, 2021, Pages 1613-1623]
  • Fibroblast Propranolol-loaded electrospun nanofibrous wound dressing: From fabrication and characterization to preliminary wound healing evaluation [Volume 24, Issue 9, 2021, Pages 1279-1291]
  • Fibronectin Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease [Volume 24, Issue 6, 2021, Pages 734-743]
  • Fibronectin Effects of integrin-linked kinase on protein kinase b, glycogen synthase kinase-3β, and β-catenin molecules in ovarian cancer cells [Volume 24, Issue 11, 2021, Pages 1500-1508]
  • Fibrosis Verbascoside alleviates renal fibrosis in unilateral ureteral obstruction rats by inhibiting macrophage infiltration [Volume 24, Issue 6, 2021, Pages 752-759]
  • Fibrosis Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease [Volume 24, Issue 6, 2021, Pages 734-743]
  • Fimbriae Type1 and 3 fimbriae phenotype and genotype as suitable markers for uropathogenic bacterial pathogenesis via attachment, cell surface hydrophobicity, and biofilm formation in catheter-associated urinary tract infections (CAUTIs) [Volume 24, Issue 8, 2021, Pages 1098-1106]
  • Flagellin DNA vaccine containing Flagellin A gene induces significant immune responses against Helicobacter pylori infection: An in vivo study [Volume 24, Issue 6, 2021, Pages 796-804]
  • Flavonoids Investigating the basis for the antidepressant effects of Gleditsiae spina using an integrated metabolomic strategy [Volume 24, Issue 4, 2021, Pages 524-530]
  • Flaxseed Biomedical features of flaxseed against different pathologic situations: A narrative review [Volume 24, Issue 5, 2021, Pages 551-560]
  • Flower extract of Caragana sinica Flower extract of Caragana sinica. ameliorates Dss-induced ulcerative colitis by affecting TLR4/NF-κB and TLR4/MAPK signaling pathway in a mouse model [Volume 24, Issue 5, 2021, Pages 595-603]
  • Food intake GABAergic neurons in the nucleus accumbens regulate hedonic food intake via orexin-a expression in the lateral hypothalamus [Volume 24, Issue 9, 2021, Pages 1272-1278]
  • FOXP3 A2 adenosine receptor contributes to the development of cow’s milk protein allergy via regulating regulatory T cells [Volume 24, Issue 10, 2021, Pages 1380-1387]

G

  • GABA GABAergic neurons in the nucleus accumbens regulate hedonic food intake via orexin-a expression in the lateral hypothalamus [Volume 24, Issue 9, 2021, Pages 1272-1278]
  • Game theory Game theory applications in host-microbe interactions toward disease manifestation: Mycobacterium tuberculosis infection as an example [Volume 24, Issue 10, 2021, Pages 1324-1335]
  • Gastric protection Effects of the diphenylheptane extract of Alpinia officinarum rhizomes on ethanol-induced gastric ulcers in mice [Volume 24, Issue 5, 2021, Pages 657-665]
  • Gastric ulcer Effects of the diphenylheptane extract of Alpinia officinarum rhizomes on ethanol-induced gastric ulcers in mice [Volume 24, Issue 5, 2021, Pages 657-665]
  • Gastroenteritis Antimicrobial resistance patterns, virulence gene profiles, and genetic diversity of Salmonella enterica serotype Enteritidis isolated from patients with gastroenteritis in various Iranian cities [Volume 24, Issue 7, 2021, Pages 914-921]
  • Gastrointestinal cancers Mesenchymal stem cells as professional actors in gastrointestinal cancer therapy: From Naïve to genetically modified [Volume 24, Issue 5, 2021, Pages 561-576]
  • Gastrointestinal lumen Therapy with new generation of biodegradable and bioconjugate 3D printed artificial gastrointestinal lumen [Volume 24, Issue 3, 2021, Pages 391-399]
  • GC-MS analysis Gas chromatography-mass spectrometry profiling and analgesic, anti-inflammatory, antipyretic, and antihyperglycemic potentials of Persea americana [Volume 24, Issue 5, 2021, Pages 641-649]
  • Gene cassettes Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [Volume 24, Issue 2, 2021, Pages 136-142]
  • Gene editing Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC) [Volume 24, Issue 8, 2021, Pages 1153-1158]
  • Gene expression Gene expression of angiogenesis and apoptotic factors in female BALB/c mice with breast cancer after eight weeks of aerobic training [Volume 24, Issue 9, 2021, Pages 1196-1202]
  • Gene expression Atorvastatin modulates the expression of aging-related genes in the brain of aging induced by D-galactose in mice [Volume 24, Issue 10, 2021, Pages 1388-1394]
  • Gene knockout Knockout of PKC θ gene attenuates oleic acid-induced acute lung injury via reduction of inflammation and oxidative stress [Volume 24, Issue 7, 2021, Pages 986-991]
  • Gene regulation MicroRNAs may provide new strategies in the treatment and diagnosis of diabetic retinopathy: Importance of VEGF [Volume 24, Issue 3, 2021, Pages 267-279]
  • Gene Therapy Mesenchymal stem cells as professional actors in gastrointestinal cancer therapy: From Naïve to genetically modified [Volume 24, Issue 5, 2021, Pages 561-576]
  • Genetic Engineering Mesenchymal stem cells as professional actors in gastrointestinal cancer therapy: From Naïve to genetically modified [Volume 24, Issue 5, 2021, Pages 561-576]
  • Gerbils Changes in the expression of the B subunit of vacuolar H+-ATPase, in the hippocampus, following transient forebrain ischemia in gerbils [Volume 24, Issue 11, 2021, Pages 1482-1487]
  • GFAP Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [Volume 24, Issue 12, 2021, Pages 1709-1716]
  • Ginkgo biloba Alzheimer’s disease treatment: The share of herbal medicines [Volume 24, Issue 2, 2021, Pages 123-135]
  • Ginkgo biloba Ginkgo biloba leaf extract (EGb-761) elicits neuroprotection against cerebral ischemia/reperfusion injury by enhancement of autophagy flux in neurons in the penumbra [Volume 24, Issue 8, 2021, Pages 1138-1145]
  • Ginseng Alzheimer’s disease treatment: The share of herbal medicines [Volume 24, Issue 2, 2021, Pages 123-135]
  • Glioblastoma multiforme Pathogenic role of the SP/ NK1R system in GBM cells through inhibiting the thioredoxin system [Volume 24, Issue 4, 2021, Pages 499-505]
  • Glutamate Effects of morphine and NeuroAid on the expression levels of GluN2A and GluN3A in the hippocampus and striatum of rats [Volume 24, Issue 4, 2021, Pages 469-475]
  • Glutamic acid Role of the glutamatergic system of ventrolateral periaqueductal gray (vlPAG) in the cardiovascular responses in normal and hemorrhagic conditions in rats [Volume 24, Issue 5, 2021, Pages 586-594]
  • Glycation Glyoxalase Thiamine reduced metabolic syndrome symptoms in rats via down-regulation of hepatic nuclear factor-kβ and induction activity of glyoxalase-I [Volume 24, Issue 3, 2021, Pages 293-299]
  • Glycochenodeoxycholic acid Vitexin ameliorates GCDC-induced hepatocyte injury through SIRT6 and JAK2/STAT3 pathways [Volume 24, Issue 12, 2021, Pages 1717-1725]
  • Glycolysis Lettuce-avicularin treatment reverses insulin resistance through stimulation of glycolytic kinases and insulin signaling molecules [Volume 24, Issue 2, 2021, Pages 232-239]
  • GO and KEGG pathways Different microRNAs contribute to the protective effect of mesenchymal stem cell-derived microvesicles in LPS induced acute respiratory distress syndrome [Volume 24, Issue 12, 2021, Pages 1702-1708]
  • Gold Nanoparticles Preparation and immunological properties of a nanovaccine against Pseudomonas aeruginosa based on gold nanoparticles and detoxified lipopolysaccharide [Volume 24, Issue 2, 2021, Pages 203-212]
  • Gold Nanoparticles Preparation and evaluation of the exotoxin A nano-gold conjugate as a vaccine candidate for Pseudomonas aeruginosa infections [Volume 24, Issue 10, 2021, Pages 1366-1372]
  • Grafting Sustained release of linezolid in ocular insert based on lipophilic modified structure of sodium alginate [Volume 24, Issue 3, 2021, Pages 331-340]
  • Granulocyte colony-stimulating factor G-CSF augments the neuroprotective effect of conditioned medium of dental pulp stem cells against hypoxic neural injury in SH-SY5Y cells [Volume 24, Issue 12, 2021, Pages 1743-1752]
  • Groove binding Description of the calf thymus DNA-malathion complex behavior by multi-spectroscopic and molecular modeling techniques: EMF at low and high frequency approaches [Volume 24, Issue 10, 2021, Pages 1346-1357]
  • Growth and Development Spatial and temporal changes in the PGE2 EP2 receptor in mice hippocampi during postnatal development and its relationship with cyclooxygenase-2 [Volume 24, Issue 7, 2021, Pages 908-913]
  • GSK-3beta Effects of integrin-linked kinase on protein kinase b, glycogen synthase kinase-3β, and β-catenin molecules in ovarian cancer cells [Volume 24, Issue 11, 2021, Pages 1500-1508]
  • Gut Preventive electroacupuncture ameliorates D-galactose-induced Alzheimer’s disease-like inflammation and memory deficits, probably via modulating the microbiota–gut–brain axis [Volume 24, Issue 3, 2021, Pages 341-348]

H

  • H1N1 subtype Recombinant hemagglutinin of swine H1N1 influenza virus expression in the insect cells: Formulation in Montanide ISA71 adjuvant and the potency studies [Volume 24, Issue 11, 2021, Pages 1546-1553]
  • H2A.Z Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression [Volume 24, Issue 11, 2021, Pages 1470-1481]
  • H2A.Z isoforms Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression [Volume 24, Issue 11, 2021, Pages 1470-1481]
  • HAM/TSP Evaluation of Interleukin-32 and cyclooxygenase-2 expression in HAM/TSP patients and HTLV-1 asymptomatic carriers [Volume 24, Issue 7, 2021, Pages 992-996]
  • Haplotypes MKK4 variants rs3826392 and rs3809728 are associated with susceptibility and clinicopathological features in colorectal cancer patients [Volume 24, Issue 8, 2021, Pages 1033-1040]
  • Helicobacter pylori DNA vaccine containing Flagellin A gene induces significant immune responses against Helicobacter pylori infection: An in vivo study [Volume 24, Issue 6, 2021, Pages 796-804]
  • Helicobacter pylori Evaluation of Helicobacter pylori OipA protein as a vaccine candidate and propolis as an adjuvant in C57BL/6 mice [Volume 24, Issue 9, 2021, Pages 1220-1230]
  • Hemagglutinin Novel single-chain antibodies against highly conserved epitopes in the hemagglutinin of influenza A viruses: Promising agents for universal therapies [Volume 24, Issue 1, 2021, Pages 17-23]
  • Hemagglutinin Recombinant hemagglutinin of swine H1N1 influenza virus expression in the insect cells: Formulation in Montanide ISA71 adjuvant and the potency studies [Volume 24, Issue 11, 2021, Pages 1546-1553]
  • Hematite nanorods Magnetic detection of albuminuria using hematite nanorods synthesized via chemical hydrothermal method [Volume 24, Issue 7, 2021, Pages 962-968]
  • Hemolysin In vitro identification of antimicrobial hemolytic lipopeptide from halotolerant Bacillus by Zymogram, FTIR, and GC mass analysis [Volume 24, Issue 5, 2021, Pages 666-674]
  • Hemorrhage Role of the glutamatergic system of ventrolateral periaqueductal gray (vlPAG) in the cardiovascular responses in normal and hemorrhagic conditions in rats [Volume 24, Issue 5, 2021, Pages 586-594]
  • Hepatic damage Evaluation of the protective effect curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats [Volume 24, Issue 6, 2021, Pages 760-766]
  • Hepatic encephalopathy Evaluation of the protective effect curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats [Volume 24, Issue 6, 2021, Pages 760-766]
  • Hepatic encephalopathy Thymoquinone improves cognitive and hippocampal long-term potentiation deficits due to hepatic encephalopathy in rats [Volume 24, Issue 7, 2021, Pages 881-891]
  • Hepatitis B Fast antibody responses by immuno-targeting and nanotechnology strategies versus HBsAg vaccine [Volume 24, Issue 4, 2021, Pages 545-550]
  • Hepatotoxicity Protective effects of selenium on acrylamide-induced neurotoxicity and hepatotoxicity in rats [Volume 24, Issue 8, 2021, Pages 1041-1049]
  • Hippocampus Neurochemical effects of sleep deprivation in the hippocampus of the pilocarpine-induced rat model of epilepsy [Volume 24, Issue 1, 2021, Pages 85-91]
  • Hippocampus Cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion [Volume 24, Issue 2, 2021, Pages 160-166]
  • Hippocampus Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosis [Volume 24, Issue 2, 2021, Pages 256-263]
  • Hippocampus Effects of morphine and NeuroAid on the expression levels of GluN2A and GluN3A in the hippocampus and striatum of rats [Volume 24, Issue 4, 2021, Pages 469-475]
  • Hippocampus Dopaminergic agonist pramipexole improves memory and increases IL-10 production in LPS-challenged rats [Volume 24, Issue 5, 2021, Pages 577-585]
  • Hippocampus Spatial and temporal changes in the PGE2 EP2 receptor in mice hippocampi during postnatal development and its relationship with cyclooxygenase-2 [Volume 24, Issue 7, 2021, Pages 908-913]
  • Hippocampus Transient receptor potential V1 modulates neuroinflammation in Parkinson’s disease dementia: Molecular implications for electroacupuncture and rivastigmine [Volume 24, Issue 10, 2021, Pages 1336-1345]
  • Hippocampus Changes in the expression of the B subunit of vacuolar H+-ATPase, in the hippocampus, following transient forebrain ischemia in gerbils [Volume 24, Issue 11, 2021, Pages 1482-1487]
  • Histological changes c-kit+ cells offer hopes in ameliorating asthmatic pathologies via regulation of miRNA-133 and -126 [Volume 24, Issue 3, 2021, Pages 369-376]
  • Histone deacetylase inhibitors In vitro anti-proliferative effect of capecitabine (Xeloda) combined with mocetinostat (MGCD0103) in 4T1 breast cancer cell line by immunoblotting [Volume 24, Issue 11, 2021, Pages 1515-1522]
  • Homeobox D4 Prognostic significance of HOXD4 protein expression in human ovarian cancers [Volume 24, Issue 11, 2021, Pages 1561-1567]
  • Homologous recombination Effect of transgenic Leishmania major expressing mLLO-Bax-Smac fusion gene in the apoptosis of the infected macrophages [Volume 24, Issue 12, 2021, Pages 1666-1675]
  • Honey Antibacterial activity of honeys and potential synergism of honeys with antibiotics and alkaloid extract of Sophora alopecuroides plant against antibiotic-resistant Escherichia coli mutant [Volume 24, Issue 5, 2021, Pages 623-628]
  • HPLC Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by Boerhavia diffusa root fraction in mdck cell lines [Volume 24, Issue 8, 2021, Pages 1087-1097]
  • HSkMC Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC) [Volume 24, Issue 8, 2021, Pages 1153-1158]
  • HTLV-1 Evaluation of Interleukin-32 and cyclooxygenase-2 expression in HAM/TSP patients and HTLV-1 asymptomatic carriers [Volume 24, Issue 7, 2021, Pages 992-996]
  • Human papillomavirus Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines [Volume 24, Issue 1, 2021, Pages 92-97]
  • Huperzine A Huperzine A protects against traumatic brain injury through anti-oxidative effects via the Nrf2-ARE pathway [Volume 24, Issue 10, 2021, Pages 1455-1461]
  • Hydrogel In vitro identification of antimicrobial hemolytic lipopeptide from halotolerant Bacillus by Zymogram, FTIR, and GC mass analysis [Volume 24, Issue 5, 2021, Pages 666-674]
  • Hydrogen sulfide Combined effect of hydrogen sulfide and mesenchymal stem cells on mitigating liver fibrosis induced by bile duct ligation: Role of anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-fibrotic biomarkers [Volume 24, Issue 12, 2021, Pages 1753-1762]
  • Hydrothermal method Magnetic detection of albuminuria using hematite nanorods synthesized via chemical hydrothermal method [Volume 24, Issue 7, 2021, Pages 962-968]
  • HYNIC-SSS-J18 Effect of using different co-ligands during 99mTc-labeling of J18 peptide on SK-MES-1 cell binding and tumor targeting [Volume 24, Issue 9, 2021, Pages 1240-1246]
  • Hypercholesterolemia Favorable effects of dill tablets and Ocimum basilicum L. extract on learning, memory, and hippocampal fatty acid composition in hypercholesterolemic rats [Volume 24, Issue 3, 2021, Pages 300-311]
  • Hyperlipidemia The protective effect of Azadirachta indica (neem) against metabolic syndrome: A review [Volume 24, Issue 3, 2021, Pages 280-292]
  • Hypertension The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review [Volume 24, Issue 1, 2021, Pages 3-16]
  • Hypertension The protective effect of Azadirachta indica (neem) against metabolic syndrome: A review [Volume 24, Issue 3, 2021, Pages 280-292]
  • Hypertension Green tea and metabolic syndrome: A 10-year research update review [Volume 24, Issue 9, 2021, Pages 1159-1172]
  • Hypertension Design and physico-mechanical evaluation of fast-dissolving valsartan polymeric drug delivery system by electrospinning method [Volume 24, Issue 12, 2021, Pages 1683-1694]
  • Hypoglycemic agents The effect of Elettaria cardamomum (cardamom) on the metabolic syndrome: Narrative review [Volume 24, Issue 11, 2021, Pages 1462-1469]
  • Hypolipidemic agents The effect of Elettaria cardamomum (cardamom) on the metabolic syndrome: Narrative review [Volume 24, Issue 11, 2021, Pages 1462-1469]
  • Hypophysis Voluntary exercise could reduce sperm malformations by improving hypothalamus-hypophysis-gonadal axis and kisspeptin/leptin signaling in type 2 diabetic rats [Volume 24, Issue 12, 2021, Pages 1624-1631]
  • Hypothalamus Voluntary exercise could reduce sperm malformations by improving hypothalamus-hypophysis-gonadal axis and kisspeptin/leptin signaling in type 2 diabetic rats [Volume 24, Issue 12, 2021, Pages 1624-1631]
  • Hypoxia G-CSF augments the neuroprotective effect of conditioned medium of dental pulp stem cells against hypoxic neural injury in SH-SY5Y cells [Volume 24, Issue 12, 2021, Pages 1743-1752]

I

  • IAPs The SMAC mimetic AT-101 exhibits anti-tumor and anti-metastasis activity in lung adenocarcinoma cells by the IAPs/ caspase-dependent apoptosis and p65-NFƙB cross-talk [Volume 24, Issue 7, 2021, Pages 969-977]
  • ICH Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [Volume 24, Issue 12, 2021, Pages 1709-1716]
  • IFN-γ Evaluation of Helicobacter pylori OipA protein as a vaccine candidate and propolis as an adjuvant in C57BL/6 mice [Volume 24, Issue 9, 2021, Pages 1220-1230]
  • IGF1 Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involved [Volume 24, Issue 6, 2021, Pages 842-850]
  • IL-10 M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system [Volume 24, Issue 11, 2021, Pages 1602-1612]
  • IL-18 Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [Volume 24, Issue 10, 2021, Pages 1421-1427]
  • IL-1β Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [Volume 24, Issue 10, 2021, Pages 1421-1427]
  • IL-4 Evaluation of Helicobacter pylori OipA protein as a vaccine candidate and propolis as an adjuvant in C57BL/6 mice [Volume 24, Issue 9, 2021, Pages 1220-1230]
  • Illicit Drugs Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen [Volume 24, Issue 7, 2021, Pages 856-867]
  • I Metabolic syndrome Nuclear factor Thiamine reduced metabolic syndrome symptoms in rats via down-regulation of hepatic nuclear factor-kβ and induction activity of glyoxalase-I [Volume 24, Issue 3, 2021, Pages 293-299]
  • Immonumodulatory Anti-inflammatory, anti-oxidant, and immunomodulatory activities of the genus Ferula and their constituents: A review [Volume 24, Issue 12, 2021, Pages 1613-1623]
  • Immune checkpoint- proteins Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4) [Volume 24, Issue 9, 2021, Pages 1264-1271]
  • Immune response Preparation and immunological properties of a nanovaccine against Pseudomonas aeruginosa based on gold nanoparticles and detoxified lipopolysaccharide [Volume 24, Issue 2, 2021, Pages 203-212]
  • Immune response Fast antibody responses by immuno-targeting and nanotechnology strategies versus HBsAg vaccine [Volume 24, Issue 4, 2021, Pages 545-550]
  • Immunization Preparation and evaluation of the exotoxin A nano-gold conjugate as a vaccine candidate for Pseudomonas aeruginosa infections [Volume 24, Issue 10, 2021, Pages 1366-1372]
  • Immunomodulation DNA vaccine containing Flagellin A gene induces significant immune responses against Helicobacter pylori infection: An in vivo study [Volume 24, Issue 6, 2021, Pages 796-804]
  • Immunomodulatory therapy Novel function of Nanos2 in expression of innate immunity genes and its probable roles in maintenance of pluripotency state [Volume 24, Issue 4, 2021, Pages 531-536]
  • Immunotherapy Novel single-chain antibodies against highly conserved epitopes in the hemagglutinin of influenza A viruses: Promising agents for universal therapies [Volume 24, Issue 1, 2021, Pages 17-23]
  • Immunotherapy Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4) [Volume 24, Issue 9, 2021, Pages 1264-1271]
  • Incretins Lettuce-avicularin treatment reverses insulin resistance through stimulation of glycolytic kinases and insulin signaling molecules [Volume 24, Issue 2, 2021, Pages 232-239]
  • Induced pluripotent stem cells In search of elixir: Pharmacological agents against stem cell senescence [Volume 24, Issue 7, 2021, Pages 868-880]
  • Infections Epidemiology and high incidence of Metallo-β-lactamase and AmpC-β-lactamases in nosocomial Pseudomonas aeruginosa [Volume 24, Issue 10, 2021, Pages 1373-1379]
  • Inflammasomes Liraglutide ameliorates myocardial damage in experimental diabetic rats by inhibiting pyroptosis via Sirt1/AMPK signaling [Volume 24, Issue 10, 2021, Pages 1358-1365]
  • Inflammation The combination of vitamin D3 and erythropoietin alleviates acute kidney injury induced by ischemia-reperfusion via inhibiting inflammation and apoptosis [Volume 24, Issue 2, 2021, Pages 167-174]
  • Inflammation Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-κB, inflammatory cytokines, iNOS, and oxidative stress [Volume 24, Issue 3, 2021, Pages 312-321]
  • Inflammation Novel function of Nanos2 in expression of innate immunity genes and its probable roles in maintenance of pluripotency state [Volume 24, Issue 4, 2021, Pages 531-536]
  • Inflammation Ameliorative effects of crocin on the inflammation and oxidative stress-induced kidney damages by experimental periodontitis in rat [Volume 24, Issue 6, 2021, Pages 825-832]
  • Inflammation Knockout of PKC θ gene attenuates oleic acid-induced acute lung injury via reduction of inflammation and oxidative stress [Volume 24, Issue 7, 2021, Pages 986-991]
  • Inflammation Evaluation of Interleukin-32 and cyclooxygenase-2 expression in HAM/TSP patients and HTLV-1 asymptomatic carriers [Volume 24, Issue 7, 2021, Pages 992-996]
  • Inflammation Cardioprotective effects of co-administration of thymoquinone and ischemic postconditioning in diabetic rats [Volume 24, Issue 7, 2021, Pages 892-899]
  • Inflammation Interaction of miR-146a-5p with oxidative stress and inflammation in complications of type 2 diabetes mellitus in male rats: antioxidant and anti-inflammatory protection strategies in type 2 diabetic retinopathy [Volume 24, Issue 8, 2021, Pages 1078-1086]
  • Inflammation A study of the transformation of umbilical cord mesenchymal stem cells by interferon-gamma [Volume 24, Issue 9, 2021, Pages 1203-1210]
  • Inflammation Irisin protects female mice with LPS-induced endometritis through the AMPK/NF-κB pathway [Volume 24, Issue 9, 2021, Pages 1247-1253]
  • Inflammation Atorvastatin modulates the expression of aging-related genes in the brain of aging induced by D-galactose in mice [Volume 24, Issue 10, 2021, Pages 1388-1394]
  • Inflammation Sperm and testicular dysfunction during cecal ligation and puncture-induced sepsis in male rats and effects of tannic acid through reducing testicular oxidative stress and inflammation [Volume 24, Issue 11, 2021, Pages 1554-1560]
  • Inflammatory cytokines Effect of pantoprazole on I-R -induced myocardial injury in diabetic rats targeting inflammatory cytokine release and oxidative stress [Volume 24, Issue 5, 2021, Pages 615-622]
  • Inflammatory cytokines Anti-arthritic activity of Ricinus communis L. and Withania somnifera L. extracts in adjuvant-induced arthritic rats via modulating inflammatory mediators and subsiding oxidative stress [Volume 24, Issue 7, 2021, Pages 951-961]
  • Influenza Recombinant hemagglutinin of swine H1N1 influenza virus expression in the insect cells: Formulation in Montanide ISA71 adjuvant and the potency studies [Volume 24, Issue 11, 2021, Pages 1546-1553]
  • Influenza A virus Novel single-chain antibodies against highly conserved epitopes in the hemagglutinin of influenza A viruses: Promising agents for universal therapies [Volume 24, Issue 1, 2021, Pages 17-23]
  • Influenza H1N1 virus Intranasal administration of immunogenic poly-epitope from influenza H1N1 and H3N2 viruses adjuvanted with chitin and chitosan microparticles in BALB/c mice [Volume 24, Issue 8, 2021, Pages 1126-1137]
  • Influenza H3N2 virus Intranasal administration of immunogenic poly-epitope from influenza H1N1 and H3N2 viruses adjuvanted with chitin and chitosan microparticles in BALB/c mice [Volume 24, Issue 8, 2021, Pages 1126-1137]
  • Infralimbic medial prefrontal cortex In vivo blockade of 5HT3 receptors in the infralimbic medial prefrontal cortex enhances fear extinction in a rat model of PTSD [Volume 24, Issue 6, 2021, Pages 776-786]
  • Inhaled vaccine Intranasal administration of immunogenic poly-epitope from influenza H1N1 and H3N2 viruses adjuvanted with chitin and chitosan microparticles in BALB/c mice [Volume 24, Issue 8, 2021, Pages 1126-1137]
  • Innate immunity Novel function of Nanos2 in expression of innate immunity genes and its probable roles in maintenance of pluripotency state [Volume 24, Issue 4, 2021, Pages 531-536]
  • Insulin signaling Lettuce-avicularin treatment reverses insulin resistance through stimulation of glycolytic kinases and insulin signaling molecules [Volume 24, Issue 2, 2021, Pages 232-239]
  • Integrases Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [Volume 24, Issue 2, 2021, Pages 136-142]
  • Integration Effect of transgenic Leishmania major expressing mLLO-Bax-Smac fusion gene in the apoptosis of the infected macrophages [Volume 24, Issue 12, 2021, Pages 1666-1675]
  • Integrin Effects of integrin-linked kinase on protein kinase b, glycogen synthase kinase-3β, and β-catenin molecules in ovarian cancer cells [Volume 24, Issue 11, 2021, Pages 1500-1508]
  • Integrons Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [Volume 24, Issue 2, 2021, Pages 136-142]
  • Interleukin-32 Evaluation of Interleukin-32 and cyclooxygenase-2 expression in HAM/TSP patients and HTLV-1 asymptomatic carriers [Volume 24, Issue 7, 2021, Pages 992-996]
  • Interleukin-6 Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction [Volume 24, Issue 10, 2021, Pages 1437-1445]
  • Intracerebral Differential pathogenesis of intracerebral and intramuscular inoculation of street rabies virus and CVS-11 strains in a mouse model [Volume 24, Issue 7, 2021, Pages 943-950]
  • Intracranial pressure Evaluation of the protective effect curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats [Volume 24, Issue 6, 2021, Pages 760-766]
  • Intramuscular Differential pathogenesis of intracerebral and intramuscular inoculation of street rabies virus and CVS-11 strains in a mouse model [Volume 24, Issue 7, 2021, Pages 943-950]
  • In Vitro Techniques Respiratory syncytial virus infection of microglia exacerbates SH-SY5Y neuronal cell injury by inducing the secretion of inflammatory cytokines: A Transwell in vitro study [Volume 24, Issue 2, 2021, Pages 213-221]
  • In vivo In vivo murine breast cancer targeting by magnetic iron nanoparticles involving L. GG cytoplasmic fraction [Volume 24, Issue 5, 2021, Pages 682-689]
  • In vivo DNA vaccine containing Flagellin A gene induces significant immune responses against Helicobacter pylori infection: An in vivo study [Volume 24, Issue 6, 2021, Pages 796-804]
  • Iran Rifampicin-resistant tuberculosis in Iran: A systematic review and meta-analysis [Volume 24, Issue 6, 2021, Pages 720-725]
  • Irisin Irisin protects female mice with LPS-induced endometritis through the AMPK/NF-κB pathway [Volume 24, Issue 9, 2021, Pages 1247-1253]
  • Iron oxide nanoparticle Fast antibody responses by immuno-targeting and nanotechnology strategies versus HBsAg vaccine [Volume 24, Issue 4, 2021, Pages 545-550]
  • Ischemia Synthesis and evaluation of 99mTc-DOTA-ARA-290 as potential SPECT tracer for targeting cardiac ischemic region [Volume 24, Issue 11, 2021, Pages 1488-1499]
  • Ischemia Changes in the expression of the B subunit of vacuolar H+-ATPase, in the hippocampus, following transient forebrain ischemia in gerbils [Volume 24, Issue 11, 2021, Pages 1482-1487]
  • Ischemic postconditioning Cardioprotective effects of co-administration of thymoquinone and ischemic postconditioning in diabetic rats [Volume 24, Issue 7, 2021, Pages 892-899]
  • Ischemic post-conditioning Ischemic post-conditioning is neuroprotective even at delayed tPA administration after embolic stroke in female rats [Volume 24, Issue 12, 2021, Pages 1676-1682]
  • Ischemic stroke Ginkgo biloba leaf extract (EGb-761) elicits neuroprotection against cerebral ischemia/reperfusion injury by enhancement of autophagy flux in neurons in the penumbra [Volume 24, Issue 8, 2021, Pages 1138-1145]

J

  • JAK/STAT1 LILRA3 is related to monocyte-derived dendritic cell maturation and activation [Volume 24, Issue 2, 2021, Pages 196-202]

K

  • Kidney damage Ameliorative effects of crocin on the inflammation and oxidative stress-induced kidney damages by experimental periodontitis in rat [Volume 24, Issue 6, 2021, Pages 825-832]
  • Kidney disease Magnetic detection of albuminuria using hematite nanorods synthesized via chemical hydrothermal method [Volume 24, Issue 7, 2021, Pages 962-968]
  • Kisspeptin Voluntary exercise could reduce sperm malformations by improving hypothalamus-hypophysis-gonadal axis and kisspeptin/leptin signaling in type 2 diabetic rats [Volume 24, Issue 12, 2021, Pages 1624-1631]

L

  • Lactobacillus Delbrueckii Inhibitory effects of tolerogenic probiotics on migratory potential of lupus patient-derived DCs [Volume 24, Issue 11, 2021, Pages 1509-1514]
  • Lactobacillus Rhamnosus Inhibitory effects of tolerogenic probiotics on migratory potential of lupus patient-derived DCs [Volume 24, Issue 11, 2021, Pages 1509-1514]
  • Lambda-Like Phage Isolation, characterization, and effectiveness of bacteriophage Pɸ-Bw-Ab against XDR Acinetobacter baumannii isolated from nosocomial burn wound infection [Volume 24, Issue 9, 2021, Pages 1254-1263]
  • Lapatinib Metformin synergistically increases the anticancer effects of lapatinib through induction of apoptosis and modulation of Akt/AMPK pathway in SK-BR3 breast cancer cell line [Volume 24, Issue 11, 2021, Pages 1529-1537]
  • LasA protease Evaluation of kinetic stability and anti-staphylococcal activity of recombinant LasA protein produced in Escherichia coli [Volume 24, Issue 6, 2021, Pages 851-855]
  • Lavandula angustifolia Alzheimer’s disease treatment: The share of herbal medicines [Volume 24, Issue 2, 2021, Pages 123-135]
  • L-DOPA Neuroprotective effects of Wharton’s jelly-derived mesenchymal stem cells on motor deficits due to Parkinson’s disease [Volume 24, Issue 9, 2021, Pages 1173-1181]
  • Learning Favorable effects of dill tablets and Ocimum basilicum L. extract on learning, memory, and hippocampal fatty acid composition in hypercholesterolemic rats [Volume 24, Issue 3, 2021, Pages 300-311]
  • Learning-memory The impact of moderate-intensity swimming exercise on learning and memory in aged rats: The role of Sirtuin-1 [Volume 24, Issue 10, 2021, Pages 1413-1420]
  • Leishmaniasis Effect of transgenic Leishmania major expressing mLLO-Bax-Smac fusion gene in the apoptosis of the infected macrophages [Volume 24, Issue 12, 2021, Pages 1666-1675]
  • Leptin Voluntary exercise could reduce sperm malformations by improving hypothalamus-hypophysis-gonadal axis and kisspeptin/leptin signaling in type 2 diabetic rats [Volume 24, Issue 12, 2021, Pages 1624-1631]
  • Leptin receptor Protective effects of selenium on electromagnetic field-induced apoptosis, aromatase P450 activity, and leptin receptor expression in rat testis [Volume 24, Issue 3, 2021, Pages 322-330]
  • Lettuce Lettuce-avicularin treatment reverses insulin resistance through stimulation of glycolytic kinases and insulin signaling molecules [Volume 24, Issue 2, 2021, Pages 232-239]
  • Licochalcone A Pretreatment with licochalcone a enhances therapeutic activity of rat bone marrow mesenchymal stem cells in animal models of colitis [Volume 24, Issue 8, 2021, Pages 1050-1057]
  • LILRA3 LILRA3 is related to monocyte-derived dendritic cell maturation and activation [Volume 24, Issue 2, 2021, Pages 196-202]
  • Linezolid Sustained release of linezolid in ocular insert based on lipophilic modified structure of sodium alginate [Volume 24, Issue 3, 2021, Pages 331-340]
  • Linker Effect of using different co-ligands during 99mTc-labeling of J18 peptide on SK-MES-1 cell binding and tumor targeting [Volume 24, Issue 9, 2021, Pages 1240-1246]
  • Linker histone Impact of linker histone in the formation of ambochlorin-calf thymus DNA complex: Multi-spectroscopic, stopped-flow, and molecular modeling approaches [Volume 24, Issue 11, 2021, Pages 1568-1582]
  • Lipid metabolism disorders Curcumin protects human umbilical vein endothelial cells against high oxidized low density lipoprotein-induced lipotoxicity and modulates autophagy [Volume 24, Issue 12, 2021, Pages 1734-1742]
  • Lipopeptide In vitro identification of antimicrobial hemolytic lipopeptide from halotolerant Bacillus by Zymogram, FTIR, and GC mass analysis [Volume 24, Issue 5, 2021, Pages 666-674]
  • Lipopolysaccharide Brucella abortus RB51 lipopolysaccharide influence as an adjuvant on the therapeutic efficacy of HPV16 L1 and HPV16 E7 DNA vaccines [Volume 24, Issue 1, 2021, Pages 92-97]
  • Lipopolysaccharide Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy [Volume 24, Issue 1, 2021, Pages 38-43]
  • Lipopolysaccharide Preparation and immunological properties of a nanovaccine against Pseudomonas aeruginosa based on gold nanoparticles and detoxified lipopolysaccharide [Volume 24, Issue 2, 2021, Pages 203-212]
  • Lipopolysaccharide Dopaminergic agonist pramipexole improves memory and increases IL-10 production in LPS-challenged rats [Volume 24, Issue 5, 2021, Pages 577-585]
  • Lipopolysaccharide NF-κB Irisin protects female mice with LPS-induced endometritis through the AMPK/NF-κB pathway [Volume 24, Issue 9, 2021, Pages 1247-1253]
  • Liver fibrosis Combined effect of hydrogen sulfide and mesenchymal stem cells on mitigating liver fibrosis induced by bile duct ligation: Role of anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-fibrotic biomarkers [Volume 24, Issue 12, 2021, Pages 1753-1762]
  • Liver Steatosis Tertiary butylhydroquinone alleviated liver steatosis and increased cell survival via β-arrestin-2/PI3K/AKT pathway [Volume 24, Issue 10, 2021, Pages 1428-1436]
  • LPS Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7) [Volume 24, Issue 12, 2021, Pages 1656-1665]
  • LTP Thymoquinone improves cognitive and hippocampal long-term potentiation deficits due to hepatic encephalopathy in rats [Volume 24, Issue 7, 2021, Pages 881-891]
  • Lung c-kit+ cells offer hopes in ameliorating asthmatic pathologies via regulation of miRNA-133 and -126 [Volume 24, Issue 3, 2021, Pages 369-376]
  • Lung carcinoma targeting Effect of using different co-ligands during 99mTc-labeling of J18 peptide on SK-MES-1 cell binding and tumor targeting [Volume 24, Issue 9, 2021, Pages 1240-1246]
  • Lymphocytes Down-regulation of immune checkpoints by doxorubicin and carboplatin-containing neoadjuvant regimens in a murine breast cancer model [Volume 24, Issue 4, 2021, Pages 537-544]

M

  • M2c macrophage M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system [Volume 24, Issue 11, 2021, Pages 1602-1612]
  • Macrophage infiltration Verbascoside alleviates renal fibrosis in unilateral ureteral obstruction rats by inhibiting macrophage infiltration [Volume 24, Issue 6, 2021, Pages 752-759]
  • Magnetic detection Magnetic detection of albuminuria using hematite nanorods synthesized via chemical hydrothermal method [Volume 24, Issue 7, 2021, Pages 962-968]
  • Magnetite nanoparticle Therapy with new generation of biodegradable and bioconjugate 3D printed artificial gastrointestinal lumen [Volume 24, Issue 3, 2021, Pages 391-399]
  • Magnolia officinalis Alzheimer’s disease treatment: The share of herbal medicines [Volume 24, Issue 2, 2021, Pages 123-135]
  • Male Infertility Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen [Volume 24, Issue 7, 2021, Pages 856-867]
  • Male reproductive system Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen [Volume 24, Issue 7, 2021, Pages 856-867]
  • Mannose Fast antibody responses by immuno-targeting and nanotechnology strategies versus HBsAg vaccine [Volume 24, Issue 4, 2021, Pages 545-550]
  • MAP kinase cascade Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase pathways [Volume 24, Issue 9, 2021, Pages 1292-1300]
  • MAP Kinase Signaling System Nimodipine promotes neurite outgrowth and protects against neurotoxicity in PC12 cells [Volume 24, Issue 1, 2021, Pages 51-57]
  • MAPK p38 LILRA3 is related to monocyte-derived dendritic cell maturation and activation [Volume 24, Issue 2, 2021, Pages 196-202]
  • MAPKs Flower extract of Caragana sinica. ameliorates Dss-induced ulcerative colitis by affecting TLR4/NF-κB and TLR4/MAPK signaling pathway in a mouse model [Volume 24, Issue 5, 2021, Pages 595-603]
  • Marijuana Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen [Volume 24, Issue 7, 2021, Pages 856-867]
  • Mass spectrometry Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [Volume 24, Issue 8, 2021, Pages 1058-1068]
  • Mass system Rapid release Solubility X Rapid releasing naproxen Liqui-Pellet using effervescent agent and neusilin US2 [Volume 24, Issue 1, 2021, Pages 108-115]
  • MB Expression of SR-B1 receptor in breast cancer cell lines, MDA-MB-468 and MCF-7: Effect on cell proliferation and apoptosis [Volume 24, Issue 8, 2021, Pages 1069-1077]
  • MCF-7 cells Synergistic anti-cancer effects of silibinin-etoposide combination against human breast carcinoma MCF-7 and MDA-MB-231 cell lines [Volume 24, Issue 9, 2021, Pages 1211-1219]
  • MDR Correlation between antibiotic resistance and phylogenetic types among multidrug-resistant Escherichia coli isolated from urinary tract infections [Volume 24, Issue 3, 2021, Pages 400-407]
  • MDR genes Epidemiology and high incidence of Metallo-β-lactamase and AmpC-β-lactamases in nosocomial Pseudomonas aeruginosa [Volume 24, Issue 10, 2021, Pages 1373-1379]
  • Medicinal properties Biomedical features of flaxseed against different pathologic situations: A narrative review [Volume 24, Issue 5, 2021, Pages 551-560]
  • MEFV Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [Volume 24, Issue 10, 2021, Pages 1421-1427]
  • Melatonin In search of elixir: Pharmacological agents against stem cell senescence [Volume 24, Issue 7, 2021, Pages 868-880]
  • Melissa officinalis Alzheimer’s disease treatment: The share of herbal medicines [Volume 24, Issue 2, 2021, Pages 123-135]
  • Memory Cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion [Volume 24, Issue 2, 2021, Pages 160-166]
  • Memory Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosis [Volume 24, Issue 2, 2021, Pages 256-263]
  • Memory Favorable effects of dill tablets and Ocimum basilicum L. extract on learning, memory, and hippocampal fatty acid composition in hypercholesterolemic rats [Volume 24, Issue 3, 2021, Pages 300-311]
  • Mesenchymal stem cell-derived microvesicles Different microRNAs contribute to the protective effect of mesenchymal stem cell-derived microvesicles in LPS induced acute respiratory distress syndrome [Volume 24, Issue 12, 2021, Pages 1702-1708]
  • Mesenchymal stem cells Mesenchymal stem cells as professional actors in gastrointestinal cancer therapy: From Naïve to genetically modified [Volume 24, Issue 5, 2021, Pages 561-576]
  • Mesenchymal stem cells Therapeutic potential of mesenchymal stem cells for peripheral artery disease in a rat model of hindlimb ischemia [Volume 24, Issue 6, 2021, Pages 805-814]
  • Mesenchymal stem cells In search of elixir: Pharmacological agents against stem cell senescence [Volume 24, Issue 7, 2021, Pages 868-880]
  • Mesenchymal stem cells Pretreatment with licochalcone a enhances therapeutic activity of rat bone marrow mesenchymal stem cells in animal models of colitis [Volume 24, Issue 8, 2021, Pages 1050-1057]
  • Mesenchymal stem cells Neuroprotective effects of Wharton’s jelly-derived mesenchymal stem cells on motor deficits due to Parkinson’s disease [Volume 24, Issue 9, 2021, Pages 1173-1181]
  • Mesenchymal stem cells Mesenchymal stem cells in cancer therapy; the art of harnessing a foe to a friend [Volume 24, Issue 10, 2021, Pages 1307-1323]
  • Mesenchymal stem cells Mesenchymal stem cells promote caspase-3 expression of SH-SY5Y neuroblastoma cells via reducing telomerase activity and telomere length [Volume 24, Issue 11, 2021, Pages 1583-1589]
  • Mesenchymal stem cells Combined effect of hydrogen sulfide and mesenchymal stem cells on mitigating liver fibrosis induced by bile duct ligation: Role of anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-fibrotic biomarkers [Volume 24, Issue 12, 2021, Pages 1753-1762]
  • Metabolic profiling Investigating the basis for the antidepressant effects of Gleditsiae spina using an integrated metabolomic strategy [Volume 24, Issue 4, 2021, Pages 524-530]
  • Metabolomics Investigating the basis for the antidepressant effects of Gleditsiae spina using an integrated metabolomic strategy [Volume 24, Issue 4, 2021, Pages 524-530]
  • Metformin Metformin synergistically increases the anticancer effects of lapatinib through induction of apoptosis and modulation of Akt/AMPK pathway in SK-BR3 breast cancer cell line [Volume 24, Issue 11, 2021, Pages 1529-1537]
  • Mice Spatial and temporal changes in the PGE2 EP2 receptor in mice hippocampi during postnatal development and its relationship with cyclooxygenase-2 [Volume 24, Issue 7, 2021, Pages 908-913]
  • Microalgae Marine algae as emerging therapeutic alternatives for depression: A review [Volume 24, Issue 8, 2021, Pages 997-1013]
  • Microglia Respiratory syncytial virus infection of microglia exacerbates SH-SY5Y neuronal cell injury by inducing the secretion of inflammatory cytokines: A Transwell in vitro study [Volume 24, Issue 2, 2021, Pages 213-221]
  • Microglia cells Differential pathogenesis of intracerebral and intramuscular inoculation of street rabies virus and CVS-11 strains in a mouse model [Volume 24, Issue 7, 2021, Pages 943-950]
  • MicroRNA Interaction of miR-146a-5p with oxidative stress and inflammation in complications of type 2 diabetes mellitus in male rats: antioxidant and anti-inflammatory protection strategies in type 2 diabetic retinopathy [Volume 24, Issue 8, 2021, Pages 1078-1086]
  • Mifepristone Improved spatial memory, neurobehavioral outcomes, and neuroprotective effect after progesterone administration in ovariectomized rats with traumatic brain injury: Role of RU486 progesterone receptor antagonist [Volume 24, Issue 3, 2021, Pages 349-359]
  • Mitochondria Sirtuin 3 deficiency promotes acute kidney injury induced by sepsis via mitochondrial dysfunction and apoptosis [Volume 24, Issue 5, 2021, Pages 675-681]
  • Mitochondrial dysfunction 4-Hydroxy-3,5-di-tret-butyl cinnamic acid restores the activity of the hippocampal mitochondria in rats under permanent focal cerebral ischemia [Volume 24, Issue 11, 2021, Pages 1590-1601]
  • Mitochondrion Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice [Volume 24, Issue 12, 2021, Pages 1695-1701]
  • MKK4 MKK4 variants rs3826392 and rs3809728 are associated with susceptibility and clinicopathological features in colorectal cancer patients [Volume 24, Issue 8, 2021, Pages 1033-1040]
  • Mobile elements Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [Volume 24, Issue 2, 2021, Pages 136-142]
  • Molecular docking Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors [Volume 24, Issue 6, 2021, Pages 815-824]
  • Molecular docking Novel oxadiazole derivatives as potent inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, in vitro evaluation, and molecular docking studies [Volume 24, Issue 12, 2021, Pages 1632-1642]
  • Molecular imaging Synthesis and evaluation of 99mTc-DOTA-ARA-290 as potential SPECT tracer for targeting cardiac ischemic region [Volume 24, Issue 11, 2021, Pages 1488-1499]
  • Molecular modeling Impact of linker histone in the formation of ambochlorin-calf thymus DNA complex: Multi-spectroscopic, stopped-flow, and molecular modeling approaches [Volume 24, Issue 11, 2021, Pages 1568-1582]
  • Molecular pathway Role of the mesenchymal stem cells derived from adipose tissue in changing the rate of breast cancer cell proliferation and autophagy, in vitro and in vivo [Volume 24, Issue 1, 2021, Pages 98-107]
  • Molecular targeted therapies Mesenchymal stem cells in cancer therapy; the art of harnessing a foe to a friend [Volume 24, Issue 10, 2021, Pages 1307-1323]
  • Molecular targeting MicroRNAs may provide new strategies in the treatment and diagnosis of diabetic retinopathy: Importance of VEGF [Volume 24, Issue 3, 2021, Pages 267-279]
  • Monocyte LILRA3 is related to monocyte-derived dendritic cell maturation and activation [Volume 24, Issue 2, 2021, Pages 196-202]
  • Morphine Effects of morphine and NeuroAid on the expression levels of GluN2A and GluN3A in the hippocampus and striatum of rats [Volume 24, Issue 4, 2021, Pages 469-475]
  • Mouse Propranolol-loaded electrospun nanofibrous wound dressing: From fabrication and characterization to preliminary wound healing evaluation [Volume 24, Issue 9, 2021, Pages 1279-1291]
  • MRSA Evaluation of kinetic stability and anti-staphylococcal activity of recombinant LasA protein produced in Escherichia coli [Volume 24, Issue 6, 2021, Pages 851-855]
  • MT-2 cells Combination of auraptene and arsenic trioxide induces apoptosis and cellular accumulation in the subG1 phase in adult T-cell leukemia cells [Volume 24, Issue 12, 2021, Pages 1643-1649]
  • MTT Assay Novel oxadiazole derivatives as potent inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, in vitro evaluation, and molecular docking studies [Volume 24, Issue 12, 2021, Pages 1632-1642]
  • M. tuberculosis antigens Game theory applications in host-microbe interactions toward disease manifestation: Mycobacterium tuberculosis infection as an example [Volume 24, Issue 10, 2021, Pages 1324-1335]
  • Multidrug resistance Growing emergence of drug-resistant Pseudomonas aeruginosa and attenuation of its virulence using quorum sensing inhibitors: A critical review [Volume 24, Issue 6, 2021, Pages 699-719]
  • Multi-drug resistance protein Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors [Volume 24, Issue 6, 2021, Pages 815-824]
  • Multi-drug resistance protein inhibitor Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors [Volume 24, Issue 6, 2021, Pages 815-824]
  • Multiple Sclerosis Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosis [Volume 24, Issue 2, 2021, Pages 256-263]
  • Multiple Sclerosis Anti-LINGO -1 improved remyelination and neurobehavioral deficit in cuprizone-induced demyelination [Volume 24, Issue 7, 2021, Pages 900-907]
  • Muscle atrophy Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice [Volume 24, Issue 12, 2021, Pages 1695-1701]
  • Muscle-invasive bladder cancer Development and immunohistochemical characterization of patient-derived xenograft models for muscle invasive bladder cancer [Volume 24, Issue 12, 2021, Pages 1650-1655]
  • Mycobacterium tuberculosis Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [Volume 24, Issue 8, 2021, Pages 1058-1068]
  • Mycobacterium tuberculosis Game theory applications in host-microbe interactions toward disease manifestation: Mycobacterium tuberculosis infection as an example [Volume 24, Issue 10, 2021, Pages 1324-1335]
  • Myelin basic protein Anti-LINGO -1 improved remyelination and neurobehavioral deficit in cuprizone-induced demyelination [Volume 24, Issue 7, 2021, Pages 900-907]
  • Myocardial I/R insult Effect of pantoprazole on I-R -induced myocardial injury in diabetic rats targeting inflammatory cytokine release and oxidative stress [Volume 24, Issue 5, 2021, Pages 615-622]

N

  • Nanobody Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4) [Volume 24, Issue 9, 2021, Pages 1264-1271]
  • Nanobody Development of camelid monoclonal nanobody against SLC39A6 zinc transporter protein [Volume 24, Issue 12, 2021, Pages 1726-1733]
  • Nanofiber Design and physico-mechanical evaluation of fast-dissolving valsartan polymeric drug delivery system by electrospinning method [Volume 24, Issue 12, 2021, Pages 1683-1694]
  • Nanoparticles In vivo murine breast cancer targeting by magnetic iron nanoparticles involving L. GG cytoplasmic fraction [Volume 24, Issue 5, 2021, Pages 682-689]
  • Nanoparticles Effects of synthetic silymarin-PLGA nanoparticles on M2 polarization and inflammatory cytokines in LPS-treated murine peritoneal macrophages [Volume 24, Issue 10, 2021, Pages 1446-1454]
  • Nanoparticles Evaluation of debridement effects of bromelain-loaded sodium alginate nanoparticles incorporated into chitosan hydrogel in animal models [Volume 24, Issue 10, 2021, Pages 1404-1412]
  • Nanovaccine Preparation and immunological properties of a nanovaccine against Pseudomonas aeruginosa based on gold nanoparticles and detoxified lipopolysaccharide [Volume 24, Issue 2, 2021, Pages 203-212]
  • Natural Zerumbone mediates apoptosis and induces secretion of proinflammatory cytokines in breast carcinoma cell culture [Volume 24, Issue 11, 2021, Pages 1538-1545]
  • NCI-H522 The SMAC mimetic AT-101 exhibits anti-tumor and anti-metastasis activity in lung adenocarcinoma cells by the IAPs/ caspase-dependent apoptosis and p65-NFƙB cross-talk [Volume 24, Issue 7, 2021, Pages 969-977]
  • Necroptosis Vitexin ameliorates GCDC-induced hepatocyte injury through SIRT6 and JAK2/STAT3 pathways [Volume 24, Issue 12, 2021, Pages 1717-1725]
  • Necrosis Cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion [Volume 24, Issue 2, 2021, Pages 160-166]
  • Neem The protective effect of Azadirachta indica (neem) against metabolic syndrome: A review [Volume 24, Issue 3, 2021, Pages 280-292]
  • Neoplasm Tumor microenvironment Mesenchymal stem cells in cancer therapy; the art of harnessing a foe to a friend [Volume 24, Issue 10, 2021, Pages 1307-1323]
  • Nephrotoxicity Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by Boerhavia diffusa root fraction in mdck cell lines [Volume 24, Issue 8, 2021, Pages 1087-1097]
  • Nerve growth factors Adrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons [Volume 24, Issue 7, 2021, Pages 978-985]
  • NeuroAid Effects of morphine and NeuroAid on the expression levels of GluN2A and GluN3A in the hippocampus and striatum of rats [Volume 24, Issue 4, 2021, Pages 469-475]
  • Neuroaxonal dystrophies PLA2G6 gene mutation and infantile neuroaxonal degeneration; report of three cases from Iran [Volume 24, Issue 9, 2021, Pages 1190-1195]
  • Neuroblastoma Mesenchymal stem cells promote caspase-3 expression of SH-SY5Y neuroblastoma cells via reducing telomerase activity and telomere length [Volume 24, Issue 11, 2021, Pages 1583-1589]
  • Neurodegeneration Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction [Volume 24, Issue 10, 2021, Pages 1437-1445]
  • Neuroinflammation Dopaminergic agonist pramipexole improves memory and increases IL-10 production in LPS-challenged rats [Volume 24, Issue 5, 2021, Pages 577-585]
  • Neuroinflammation Marine algae as emerging therapeutic alternatives for depression: A review [Volume 24, Issue 8, 2021, Pages 997-1013]
  • Neuroinflammation Transient receptor potential V1 modulates neuroinflammation in Parkinson’s disease dementia: Molecular implications for electroacupuncture and rivastigmine [Volume 24, Issue 10, 2021, Pages 1336-1345]
  • Neurokinin 1 receptor Pathogenic role of the SP/ NK1R system in GBM cells through inhibiting the thioredoxin system [Volume 24, Issue 4, 2021, Pages 499-505]
  • Neuronal outgrowth Nimodipine promotes neurite outgrowth and protects against neurotoxicity in PC12 cells [Volume 24, Issue 1, 2021, Pages 51-57]
  • Neuronal plasticity Marine algae as emerging therapeutic alternatives for depression: A review [Volume 24, Issue 8, 2021, Pages 997-1013]
  • Neurons Respiratory syncytial virus infection of microglia exacerbates SH-SY5Y neuronal cell injury by inducing the secretion of inflammatory cytokines: A Transwell in vitro study [Volume 24, Issue 2, 2021, Pages 213-221]
  • Neurons Differential pathogenesis of intracerebral and intramuscular inoculation of street rabies virus and CVS-11 strains in a mouse model [Volume 24, Issue 7, 2021, Pages 943-950]
  • Neuroprotection Nimodipine promotes neurite outgrowth and protects against neurotoxicity in PC12 cells [Volume 24, Issue 1, 2021, Pages 51-57]
  • Neuroprotection Improved spatial memory, neurobehavioral outcomes, and neuroprotective effect after progesterone administration in ovariectomized rats with traumatic brain injury: Role of RU486 progesterone receptor antagonist [Volume 24, Issue 3, 2021, Pages 349-359]
  • Neuroprotection Ginkgo biloba leaf extract (EGb-761) elicits neuroprotection against cerebral ischemia/reperfusion injury by enhancement of autophagy flux in neurons in the penumbra [Volume 24, Issue 8, 2021, Pages 1138-1145]
  • Neuroprotection Huperzine A protects against traumatic brain injury through anti-oxidative effects via the Nrf2-ARE pathway [Volume 24, Issue 10, 2021, Pages 1455-1461]
  • Neuroprotection 4-Hydroxy-3,5-di-tret-butyl cinnamic acid restores the activity of the hippocampal mitochondria in rats under permanent focal cerebral ischemia [Volume 24, Issue 11, 2021, Pages 1590-1601]
  • Neuroprotection Ischemic post-conditioning is neuroprotective even at delayed tPA administration after embolic stroke in female rats [Volume 24, Issue 12, 2021, Pages 1676-1682]
  • Neurotoxicity Protective effects of selenium on acrylamide-induced neurotoxicity and hepatotoxicity in rats [Volume 24, Issue 8, 2021, Pages 1041-1049]
  • Neurotropin Neurotropin alleviates rat osteocarcinoma pain via P2X3 receptor activation in the midbrain periaqueductal gray [Volume 24, Issue 10, 2021, Pages 1395-1403]
  • Neutralizing scFvs Novel single-chain antibodies against highly conserved epitopes in the hemagglutinin of influenza A viruses: Promising agents for universal therapies [Volume 24, Issue 1, 2021, Pages 17-23]
  • NFƙB The SMAC mimetic AT-101 exhibits anti-tumor and anti-metastasis activity in lung adenocarcinoma cells by the IAPs/ caspase-dependent apoptosis and p65-NFƙB cross-talk [Volume 24, Issue 7, 2021, Pages 969-977]
  • NFκB Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [Volume 24, Issue 10, 2021, Pages 1421-1427]
  • NF-κB Flower extract of Caragana sinica. ameliorates Dss-induced ulcerative colitis by affecting TLR4/NF-κB and TLR4/MAPK signaling pathway in a mouse model [Volume 24, Issue 5, 2021, Pages 595-603]
  • NF-κB Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation [Volume 24, Issue 7, 2021, Pages 935-942]
  • Nigella Sativa Effect of orally-administrated thymoquinone during pregnancy on litter size, pentylenetetrazol-induced seizure, and body weight in rat offspring [Volume 24, Issue 1, 2021, Pages 30-37]
  • Nimodipine Nimodipine promotes neurite outgrowth and protects against neurotoxicity in PC12 cells [Volume 24, Issue 1, 2021, Pages 51-57]
  • NLRP3 Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [Volume 24, Issue 10, 2021, Pages 1421-1427]
  • Nogo Receptor 1 Anti-LINGO -1 improved remyelination and neurobehavioral deficit in cuprizone-induced demyelination [Volume 24, Issue 7, 2021, Pages 900-907]
  • Non-thermal atmospheric pressure plasma Time-dependent behavior of the Staphylococcus aureus biofilm following exposure to cold atmospheric pressure plasma [Volume 24, Issue 6, 2021, Pages 744-751]
  • Nrf2-ARE Huperzine A protects against traumatic brain injury through anti-oxidative effects via the Nrf2-ARE pathway [Volume 24, Issue 10, 2021, Pages 1455-1461]
  • NSCLC Effect of using different co-ligands during 99mTc-labeling of J18 peptide on SK-MES-1 cell binding and tumor targeting [Volume 24, Issue 9, 2021, Pages 1240-1246]
  • Nucleus accumbens GABAergic neurons in the nucleus accumbens regulate hedonic food intake via orexin-a expression in the lateral hypothalamus [Volume 24, Issue 9, 2021, Pages 1272-1278]

O

  • Obesity The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review [Volume 24, Issue 1, 2021, Pages 3-16]
  • Obesity The protective effect of Azadirachta indica (neem) against metabolic syndrome: A review [Volume 24, Issue 3, 2021, Pages 280-292]
  • Obesity GABAergic neurons in the nucleus accumbens regulate hedonic food intake via orexin-a expression in the lateral hypothalamus [Volume 24, Issue 9, 2021, Pages 1272-1278]
  • Obesity Green tea and metabolic syndrome: A 10-year research update review [Volume 24, Issue 9, 2021, Pages 1159-1172]
  • Obstructive nephropathy Verbascoside alleviates renal fibrosis in unilateral ureteral obstruction rats by inhibiting macrophage infiltration [Volume 24, Issue 6, 2021, Pages 752-759]
  • Ocimum Favorable effects of dill tablets and Ocimum basilicum L. extract on learning, memory, and hippocampal fatty acid composition in hypercholesterolemic rats [Volume 24, Issue 3, 2021, Pages 300-311]
  • Ocimum sanctum Detection of csgA gene in carbapenem-resistant Acinetobacter baumannii strains and targeting with Ocimum sanctum biocompounds [Volume 24, Issue 5, 2021, Pages 690-698]
  • Ocular insert Sustained release of linezolid in ocular insert based on lipophilic modified structure of sodium alginate [Volume 24, Issue 3, 2021, Pages 331-340]
  • OipA Evaluation of Helicobacter pylori OipA protein as a vaccine candidate and propolis as an adjuvant in C57BL/6 mice [Volume 24, Issue 9, 2021, Pages 1220-1230]
  • Oleic acid Knockout of PKC θ gene attenuates oleic acid-induced acute lung injury via reduction of inflammation and oxidative stress [Volume 24, Issue 7, 2021, Pages 986-991]
  • Onion The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review [Volume 24, Issue 1, 2021, Pages 3-16]
  • Opioids Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen [Volume 24, Issue 7, 2021, Pages 856-867]
  • Opsonophagocytosis Immunization against Pseudomonas aeruginosa using Alg-PLGA nano-vaccine [Volume 24, Issue 4, 2021, Pages 476-482]
  • Orexin-A GABAergic neurons in the nucleus accumbens regulate hedonic food intake via orexin-a expression in the lateral hypothalamus [Volume 24, Issue 9, 2021, Pages 1272-1278]
  • Organ-culture M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system [Volume 24, Issue 11, 2021, Pages 1602-1612]
  • Organoid Formation of organoid-like structures in the decellularized rat testis [Volume 24, Issue 11, 2021, Pages 1523-1528]
  • Osteocarcinoma Pain Neurotropin alleviates rat osteocarcinoma pain via P2X3 receptor activation in the midbrain periaqueductal gray [Volume 24, Issue 10, 2021, Pages 1395-1403]
  • Osteoporosis Bosentan, a drug used in the treatment of pulmonary hypertension, can prevent development of osteoporosis [Volume 24, Issue 7, 2021, Pages 922-927]
  • Ovalbumin c-kit+ cells offer hopes in ameliorating asthmatic pathologies via regulation of miRNA-133 and -126 [Volume 24, Issue 3, 2021, Pages 369-376]
  • Ovarian Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation [Volume 24, Issue 7, 2021, Pages 935-942]
  • Ovarian Neoplasms Prognostic significance of HOXD4 protein expression in human ovarian cancers [Volume 24, Issue 11, 2021, Pages 1561-1567]
  • Oxadiazole Novel oxadiazole derivatives as potent inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, in vitro evaluation, and molecular docking studies [Volume 24, Issue 12, 2021, Pages 1632-1642]
  • Oxidative stres Huperzine A protects against traumatic brain injury through anti-oxidative effects via the Nrf2-ARE pathway [Volume 24, Issue 10, 2021, Pages 1455-1461]
  • Oxidative stress Neurochemical effects of sleep deprivation in the hippocampus of the pilocarpine-induced rat model of epilepsy [Volume 24, Issue 1, 2021, Pages 85-91]
  • Oxidative stress Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-κB, inflammatory cytokines, iNOS, and oxidative stress [Volume 24, Issue 3, 2021, Pages 312-321]
  • Oxidative stress Pathogenic role of the SP/ NK1R system in GBM cells through inhibiting the thioredoxin system [Volume 24, Issue 4, 2021, Pages 499-505]
  • Oxidative stress Effect of pantoprazole on I-R -induced myocardial injury in diabetic rats targeting inflammatory cytokine release and oxidative stress [Volume 24, Issue 5, 2021, Pages 615-622]
  • Oxidative stress Quercetin protects islet β‑cells from oxidation-induced apoptosis via Sirt3 in T2DM [Volume 24, Issue 5, 2021, Pages 629-635]
  • Oxidative stress Ameliorative effects of crocin on the inflammation and oxidative stress-induced kidney damages by experimental periodontitis in rat [Volume 24, Issue 6, 2021, Pages 825-832]
  • Oxidative stress Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involved [Volume 24, Issue 6, 2021, Pages 842-850]
  • Oxidative stress Knockout of PKC θ gene attenuates oleic acid-induced acute lung injury via reduction of inflammation and oxidative stress [Volume 24, Issue 7, 2021, Pages 986-991]
  • Oxidative stress Anti-arthritic activity of Ricinus communis L. and Withania somnifera L. extracts in adjuvant-induced arthritic rats via modulating inflammatory mediators and subsiding oxidative stress [Volume 24, Issue 7, 2021, Pages 951-961]
  • Oxidative stress Thymoquinone improves cognitive and hippocampal long-term potentiation deficits due to hepatic encephalopathy in rats [Volume 24, Issue 7, 2021, Pages 881-891]
  • Oxidative stress Protective effects of selenium on acrylamide-induced neurotoxicity and hepatotoxicity in rats [Volume 24, Issue 8, 2021, Pages 1041-1049]
  • Oxidative stress Interaction of miR-146a-5p with oxidative stress and inflammation in complications of type 2 diabetes mellitus in male rats: antioxidant and anti-inflammatory protection strategies in type 2 diabetic retinopathy [Volume 24, Issue 8, 2021, Pages 1078-1086]
  • Oxidative stress Propranolol-loaded electrospun nanofibrous wound dressing: From fabrication and characterization to preliminary wound healing evaluation [Volume 24, Issue 9, 2021, Pages 1279-1291]
  • Oxidative stress Differential expressions of miR-223, miR-424, miR-145, miR-200c, miR-139 in experimental rat chronic pancreatitis model and their relationship between oxidative stress, endoplasmic reticulum stress, and apoptosis [Volume 24, Issue 9, 2021, Pages 1301-1306]
  • Oxidative stress Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction [Volume 24, Issue 10, 2021, Pages 1437-1445]
  • Oxidative stress 4-Hydroxy-3,5-di-tret-butyl cinnamic acid restores the activity of the hippocampal mitochondria in rats under permanent focal cerebral ischemia [Volume 24, Issue 11, 2021, Pages 1590-1601]
  • Oxidative stress Sperm and testicular dysfunction during cecal ligation and puncture-induced sepsis in male rats and effects of tannic acid through reducing testicular oxidative stress and inflammation [Volume 24, Issue 11, 2021, Pages 1554-1560]
  • Oxidative stress Vitexin ameliorates GCDC-induced hepatocyte injury through SIRT6 and JAK2/STAT3 pathways [Volume 24, Issue 12, 2021, Pages 1717-1725]

P

  • P2X3 receptor Neurotropin alleviates rat osteocarcinoma pain via P2X3 receptor activation in the midbrain periaqueductal gray [Volume 24, Issue 10, 2021, Pages 1395-1403]
  • P. aeruginosa Growing emergence of drug-resistant Pseudomonas aeruginosa and attenuation of its virulence using quorum sensing inhibitors: A critical review [Volume 24, Issue 6, 2021, Pages 699-719]
  • Pancreatic Cancer PANC-1 cancer stem-like cell death with silybin encapsulated in polymersomes and deregulation of stemness-related miRNAs and their potential targets [Volume 24, Issue 4, 2021, Pages 514-523]
  • Pantoprazole Effect of pantoprazole on I-R -induced myocardial injury in diabetic rats targeting inflammatory cytokine release and oxidative stress [Volume 24, Issue 5, 2021, Pages 615-622]
  • Pantothenate kinase associated neuro degeneration PLA2G6 gene mutation and infantile neuroaxonal degeneration; report of three cases from Iran [Volume 24, Issue 9, 2021, Pages 1190-1195]
  • Paraoxonase Inhibition of aluminum chloride-induced amyloid Aβ peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction [Volume 24, Issue 10, 2021, Pages 1437-1445]
  • Parkinson's disease Neuroprotective effects of Wharton’s jelly-derived mesenchymal stem cells on motor deficits due to Parkinson’s disease [Volume 24, Issue 9, 2021, Pages 1173-1181]
  • Parkinson’s disease dementia Transient receptor potential V1 modulates neuroinflammation in Parkinson’s disease dementia: Molecular implications for electroacupuncture and rivastigmine [Volume 24, Issue 10, 2021, Pages 1336-1345]
  • Passive avoidance memory The bidirectional effect of prelimbic 5-hydroxytryptamine type-4 (5-HT4) receptors on ACPA-mediated aversive memory impairment in adult male Sprague-Dawley rats [Volume 24, Issue 6, 2021, Pages 726-733]
  • Patient-derived xenograft Development and immunohistochemical characterization of patient-derived xenograft models for muscle invasive bladder cancer [Volume 24, Issue 12, 2021, Pages 1650-1655]
  • Paw regeneration M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system [Volume 24, Issue 11, 2021, Pages 1602-1612]
  • PCR Correlation between antibiotic resistance and phylogenetic types among multidrug-resistant Escherichia coli isolated from urinary tract infections [Volume 24, Issue 3, 2021, Pages 400-407]
  • PD-L1 A study of the transformation of umbilical cord mesenchymal stem cells by interferon-gamma [Volume 24, Issue 9, 2021, Pages 1203-1210]
  • Peas Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease [Volume 24, Issue 6, 2021, Pages 734-743]
  • Pentylenetetrazol Effect of orally-administrated thymoquinone during pregnancy on litter size, pentylenetetrazol-induced seizure, and body weight in rat offspring [Volume 24, Issue 1, 2021, Pages 30-37]
  • Peptide synthases RNA Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [Volume 24, Issue 8, 2021, Pages 1058-1068]
  • Periaqueductal gray Role of the glutamatergic system of ventrolateral periaqueductal gray (vlPAG) in the cardiovascular responses in normal and hemorrhagic conditions in rats [Volume 24, Issue 5, 2021, Pages 586-594]
  • Periaqueductal gray Neurotropin alleviates rat osteocarcinoma pain via P2X3 receptor activation in the midbrain periaqueductal gray [Volume 24, Issue 10, 2021, Pages 1395-1403]
  • Periodontitis Ameliorative effects of crocin on the inflammation and oxidative stress-induced kidney damages by experimental periodontitis in rat [Volume 24, Issue 6, 2021, Pages 825-832]
  • Peripheral blood mononuclear cells Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells [Volume 24, Issue 1, 2021, Pages 73-78]
  • Peripheral vascular disease Therapeutic potential of mesenchymal stem cells for peripheral artery disease in a rat model of hindlimb ischemia [Volume 24, Issue 6, 2021, Pages 805-814]
  • Peritoneal macrophages Effects of synthetic silymarin-PLGA nanoparticles on M2 polarization and inflammatory cytokines in LPS-treated murine peritoneal macrophages [Volume 24, Issue 10, 2021, Pages 1446-1454]
  • Persea americana Gas chromatography-mass spectrometry profiling and analgesic, anti-inflammatory, antipyretic, and antihyperglycemic potentials of Persea americana [Volume 24, Issue 5, 2021, Pages 641-649]
  • PFGE Antimicrobial resistance patterns, virulence gene profiles, and genetic diversity of Salmonella enterica serotype Enteritidis isolated from patients with gastroenteritis in various Iranian cities [Volume 24, Issue 7, 2021, Pages 914-921]
  • Phage display Development of camelid monoclonal nanobody against SLC39A6 zinc transporter protein [Volume 24, Issue 12, 2021, Pages 1726-1733]
  • Phthalimide Cytotoxicity and pro‐apoptosis activity of synthetic 1,3-thiazole incorporated phthalimide derivatives on cancer cells [Volume 24, Issue 5, 2021, Pages 604-614]
  • PI3K β-LAPachone is renoprotective in streptozotocin-induced diabetic mice via regulating the PI3K/Akt/mTOR signaling pathway [Volume 24, Issue 5, 2021, Pages 650-656]
  • Pisum sativum Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease [Volume 24, Issue 6, 2021, Pages 734-743]
  • PLGA Immunization against Pseudomonas aeruginosa using Alg-PLGA nano-vaccine [Volume 24, Issue 4, 2021, Pages 476-482]
  • PLGA compound Effects of synthetic silymarin-PLGA nanoparticles on M2 polarization and inflammatory cytokines in LPS-treated murine peritoneal macrophages [Volume 24, Issue 10, 2021, Pages 1446-1454]
  • Polyacrylamide Gel In vitro identification of antimicrobial hemolytic lipopeptide from halotolerant Bacillus by Zymogram, FTIR, and GC mass analysis [Volume 24, Issue 5, 2021, Pages 666-674]
  • Polymers Design and physico-mechanical evaluation of fast-dissolving valsartan polymeric drug delivery system by electrospinning method [Volume 24, Issue 12, 2021, Pages 1683-1694]
  • Polymersome PANC-1 cancer stem-like cell death with silybin encapsulated in polymersomes and deregulation of stemness-related miRNAs and their potential targets [Volume 24, Issue 4, 2021, Pages 514-523]
  • Polyphenols Cardioprotective effects of co-administration of thymoquinone and ischemic postconditioning in diabetic rats [Volume 24, Issue 7, 2021, Pages 892-899]
  • Polyurethane Therapy with new generation of biodegradable and bioconjugate 3D printed artificial gastrointestinal lumen [Volume 24, Issue 3, 2021, Pages 391-399]
  • Polyvinylpyrrolidone Design and physico-mechanical evaluation of fast-dissolving valsartan polymeric drug delivery system by electrospinning method [Volume 24, Issue 12, 2021, Pages 1683-1694]
  • Pramipexole Dopaminergic agonist pramipexole improves memory and increases IL-10 production in LPS-challenged rats [Volume 24, Issue 5, 2021, Pages 577-585]
  • Pregnancy outcomes Effect of orally-administrated thymoquinone during pregnancy on litter size, pentylenetetrazol-induced seizure, and body weight in rat offspring [Volume 24, Issue 1, 2021, Pages 30-37]
  • Pre-limbic cortex The bidirectional effect of prelimbic 5-hydroxytryptamine type-4 (5-HT4) receptors on ACPA-mediated aversive memory impairment in adult male Sprague-Dawley rats [Volume 24, Issue 6, 2021, Pages 726-733]
  • PRL receptor Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [Volume 24, Issue 12, 2021, Pages 1709-1716]
  • Probiotic In vivo murine breast cancer targeting by magnetic iron nanoparticles involving L. GG cytoplasmic fraction [Volume 24, Issue 5, 2021, Pages 682-689]
  • Progesterone Improved spatial memory, neurobehavioral outcomes, and neuroprotective effect after progesterone administration in ovariectomized rats with traumatic brain injury: Role of RU486 progesterone receptor antagonist [Volume 24, Issue 3, 2021, Pages 349-359]
  • Prognosis Prognostic significance of HOXD4 protein expression in human ovarian cancers [Volume 24, Issue 11, 2021, Pages 1561-1567]
  • Proliferation A study of the transformation of umbilical cord mesenchymal stem cells by interferon-gamma [Volume 24, Issue 9, 2021, Pages 1203-1210]
  • Proliferation Prognostic significance of HOXD4 protein expression in human ovarian cancers [Volume 24, Issue 11, 2021, Pages 1561-1567]
  • Proliferation Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression [Volume 24, Issue 11, 2021, Pages 1470-1481]
  • Promoters Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression [Volume 24, Issue 11, 2021, Pages 1470-1481]
  • Propolis Evaluation of Helicobacter pylori OipA protein as a vaccine candidate and propolis as an adjuvant in C57BL/6 mice [Volume 24, Issue 9, 2021, Pages 1220-1230]
  • Propranolol Propranolol-loaded electrospun nanofibrous wound dressing: From fabrication and characterization to preliminary wound healing evaluation [Volume 24, Issue 9, 2021, Pages 1279-1291]
  • Prostaglandin E EP2 subtype Spatial and temporal changes in the PGE2 EP2 receptor in mice hippocampi during postnatal development and its relationship with cyclooxygenase-2 [Volume 24, Issue 7, 2021, Pages 908-913]
  • Protein hydrolysates Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease [Volume 24, Issue 6, 2021, Pages 734-743]
  • Protein kinase C θ Knockout of PKC θ gene attenuates oleic acid-induced acute lung injury via reduction of inflammation and oxidative stress [Volume 24, Issue 7, 2021, Pages 986-991]
  • Pseudomonas aeruginosa Preparation and immunological properties of a nanovaccine against Pseudomonas aeruginosa based on gold nanoparticles and detoxified lipopolysaccharide [Volume 24, Issue 2, 2021, Pages 203-212]
  • Pseudomonas aeruginosa Immunization against Pseudomonas aeruginosa using Alg-PLGA nano-vaccine [Volume 24, Issue 4, 2021, Pages 476-482]
  • Pseudomonas aeruginosa Epidemiology and high incidence of Metallo-β-lactamase and AmpC-β-lactamases in nosocomial Pseudomonas aeruginosa [Volume 24, Issue 10, 2021, Pages 1373-1379]
  • Pseudomonas aeruginosa Preparation and evaluation of the exotoxin A nano-gold conjugate as a vaccine candidate for Pseudomonas aeruginosa infections [Volume 24, Issue 10, 2021, Pages 1366-1372]
  • PTSD In vivo blockade of 5HT3 receptors in the infralimbic medial prefrontal cortex enhances fear extinction in a rat model of PTSD [Volume 24, Issue 6, 2021, Pages 776-786]

Q

  • Quantitative real-time polymerase chain reaction Differential expressions of miR-223, miR-424, miR-145, miR-200c, miR-139 in experimental rat chronic pancreatitis model and their relationship between oxidative stress, endoplasmic reticulum stress, and apoptosis [Volume 24, Issue 9, 2021, Pages 1301-1306]
  • Quercetin The effects of Allium cepa L. (onion) and its active constituents on metabolic syndrome: A review [Volume 24, Issue 1, 2021, Pages 3-16]
  • Quercetin Quercetin protects islet β‑cells from oxidation-induced apoptosis via Sirt3 in T2DM [Volume 24, Issue 5, 2021, Pages 629-635]
  • Quercetin Quercetin synergistically potentiates the anti-metastatic effect of 5-fluorouracil on the MDA-MB-231 breast cancer cell line [Volume 24, Issue 7, 2021, Pages 928-934]
  • Quercetin Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by Boerhavia diffusa root fraction in mdck cell lines [Volume 24, Issue 8, 2021, Pages 1087-1097]
  • Quinoline Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors [Volume 24, Issue 6, 2021, Pages 815-824]
  • Quorum sensing inhibitors Growing emergence of drug-resistant Pseudomonas aeruginosa and attenuation of its virulence using quorum sensing inhibitors: A critical review [Volume 24, Issue 6, 2021, Pages 699-719]

R

  • Rat c-kit+ cells offer hopes in ameliorating asthmatic pathologies via regulation of miRNA-133 and -126 [Volume 24, Issue 3, 2021, Pages 369-376]
  • Rat Ameliorative effects of crocin on the inflammation and oxidative stress-induced kidney damages by experimental periodontitis in rat [Volume 24, Issue 6, 2021, Pages 825-832]
  • Rat Neuroprotective effects of Wharton’s jelly-derived mesenchymal stem cells on motor deficits due to Parkinson’s disease [Volume 24, Issue 9, 2021, Pages 1173-1181]
  • Rat Differential expressions of miR-223, miR-424, miR-145, miR-200c, miR-139 in experimental rat chronic pancreatitis model and their relationship between oxidative stress, endoplasmic reticulum stress, and apoptosis [Volume 24, Issue 9, 2021, Pages 1301-1306]
  • Rats Liraglutide ameliorates myocardial damage in experimental diabetic rats by inhibiting pyroptosis via Sirt1/AMPK signaling [Volume 24, Issue 10, 2021, Pages 1358-1365]
  • RAW 264.7 Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7) [Volume 24, Issue 12, 2021, Pages 1656-1665]
  • Reactive Oxygen Species Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by Boerhavia diffusa root fraction in mdck cell lines [Volume 24, Issue 8, 2021, Pages 1087-1097]
  • Recombinant vaccine Recombinant hemagglutinin of swine H1N1 influenza virus expression in the insect cells: Formulation in Montanide ISA71 adjuvant and the potency studies [Volume 24, Issue 11, 2021, Pages 1546-1553]
  • Regenerative medicine Novel function of Nanos2 in expression of innate immunity genes and its probable roles in maintenance of pluripotency state [Volume 24, Issue 4, 2021, Pages 531-536]
  • Regulatory T cells A2 adenosine receptor contributes to the development of cow’s milk protein allergy via regulating regulatory T cells [Volume 24, Issue 10, 2021, Pages 1380-1387]
  • Remyelination Anti-LINGO -1 improved remyelination and neurobehavioral deficit in cuprizone-induced demyelination [Volume 24, Issue 7, 2021, Pages 900-907]
  • Renal fibrosis Verbascoside alleviates renal fibrosis in unilateral ureteral obstruction rats by inhibiting macrophage infiltration [Volume 24, Issue 6, 2021, Pages 752-759]
  • Respiratory syncytial virus infections Respiratory syncytial virus infection of microglia exacerbates SH-SY5Y neuronal cell injury by inducing the secretion of inflammatory cytokines: A Transwell in vitro study [Volume 24, Issue 2, 2021, Pages 213-221]
  • Restriction Enzyme-Mapping Isolation, characterization, and effectiveness of bacteriophage Pɸ-Bw-Ab against XDR Acinetobacter baumannii isolated from nosocomial burn wound infection [Volume 24, Issue 9, 2021, Pages 1254-1263]
  • Resveratrol Resveratrol increases the sensitivity of breast cancer MDA-MB-231 cell line to cisplatin by regulating intrinsic apoptosis [Volume 24, Issue 1, 2021, Pages 66-72]
  • Resveratrol Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy [Volume 24, Issue 1, 2021, Pages 38-43]
  • RGD motif Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease [Volume 24, Issue 6, 2021, Pages 734-743]
  • Rheumatoid arthritis Anti-arthritic activity of Ricinus communis L. and Withania somnifera L. extracts in adjuvant-induced arthritic rats via modulating inflammatory mediators and subsiding oxidative stress [Volume 24, Issue 7, 2021, Pages 951-961]
  • Ribosomal Potential secondary metabolite from Indonesian Actinobacteria (InaCC A758) against Mycobacterium tuberculosis [Volume 24, Issue 8, 2021, Pages 1058-1068]
  • Ricinus communis Anti-arthritic activity of Ricinus communis L. and Withania somnifera L. extracts in adjuvant-induced arthritic rats via modulating inflammatory mediators and subsiding oxidative stress [Volume 24, Issue 7, 2021, Pages 951-961]
  • Rivastigmine Transient receptor potential V1 modulates neuroinflammation in Parkinson’s disease dementia: Molecular implications for electroacupuncture and rivastigmine [Volume 24, Issue 10, 2021, Pages 1336-1345]
  • RS23597-190 The bidirectional effect of prelimbic 5-hydroxytryptamine type-4 (5-HT4) receptors on ACPA-mediated aversive memory impairment in adult male Sprague-Dawley rats [Volume 24, Issue 6, 2021, Pages 726-733]
  • RS67333 The bidirectional effect of prelimbic 5-hydroxytryptamine type-4 (5-HT4) receptors on ACPA-mediated aversive memory impairment in adult male Sprague-Dawley rats [Volume 24, Issue 6, 2021, Pages 726-733]

S

  • Salmonella enterica serotype Enteritidis Antimicrobial resistance patterns, virulence gene profiles, and genetic diversity of Salmonella enterica serotype Enteritidis isolated from patients with gastroenteritis in various Iranian cities [Volume 24, Issue 7, 2021, Pages 914-921]
  • Salvia miltiorrhiza Alzheimer’s disease treatment: The share of herbal medicines [Volume 24, Issue 2, 2021, Pages 123-135]
  • Seaweed Marine algae as emerging therapeutic alternatives for depression: A review [Volume 24, Issue 8, 2021, Pages 997-1013]
  • Seizure Effect of orally-administrated thymoquinone during pregnancy on litter size, pentylenetetrazol-induced seizure, and body weight in rat offspring [Volume 24, Issue 1, 2021, Pages 30-37]
  • Selenium Protective effects of selenium on electromagnetic field-induced apoptosis, aromatase P450 activity, and leptin receptor expression in rat testis [Volume 24, Issue 3, 2021, Pages 322-330]
  • Selenium Protective effects of selenium on acrylamide-induced neurotoxicity and hepatotoxicity in rats [Volume 24, Issue 8, 2021, Pages 1041-1049]
  • Seminiferous tubule Formation of organoid-like structures in the decellularized rat testis [Volume 24, Issue 11, 2021, Pages 1523-1528]
  • Sepsis Sirtuin 3 deficiency promotes acute kidney injury induced by sepsis via mitochondrial dysfunction and apoptosis [Volume 24, Issue 5, 2021, Pages 675-681]
  • Sepsis Sperm and testicular dysfunction during cecal ligation and puncture-induced sepsis in male rats and effects of tannic acid through reducing testicular oxidative stress and inflammation [Volume 24, Issue 11, 2021, Pages 1554-1560]
  • Signaling pathway Diabetes mellitus can cause cardiomyopathy disorders by inducing the aging pathway [Volume 24, Issue 5, 2021, Pages 636-640]
  • Signaling pathways Mesenchymal stem cells promote caspase-3 expression of SH-SY5Y neuroblastoma cells via reducing telomerase activity and telomere length [Volume 24, Issue 11, 2021, Pages 1583-1589]
  • Signaling transduction Adrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons [Volume 24, Issue 7, 2021, Pages 978-985]
  • Silibinin Synergistic anti-cancer effects of silibinin-etoposide combination against human breast carcinoma MCF-7 and MDA-MB-231 cell lines [Volume 24, Issue 9, 2021, Pages 1211-1219]
  • Silybin PANC-1 cancer stem-like cell death with silybin encapsulated in polymersomes and deregulation of stemness-related miRNAs and their potential targets [Volume 24, Issue 4, 2021, Pages 514-523]
  • Silymarin Effects of synthetic silymarin-PLGA nanoparticles on M2 polarization and inflammatory cytokines in LPS-treated murine peritoneal macrophages [Volume 24, Issue 10, 2021, Pages 1446-1454]
  • Sinapic acid Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice [Volume 24, Issue 12, 2021, Pages 1695-1701]
  • Single-domain antibodies Developing and characterizing a single-domain antibody (nanobody) against human cytotoxic T-lymphocyte-associated protein 4 (hCTLA-4) [Volume 24, Issue 9, 2021, Pages 1264-1271]
  • Single prolonged stress In vivo blockade of 5HT3 receptors in the infralimbic medial prefrontal cortex enhances fear extinction in a rat model of PTSD [Volume 24, Issue 6, 2021, Pages 776-786]
  • Sirt3 Quercetin protects islet β‑cells from oxidation-induced apoptosis via Sirt3 in T2DM [Volume 24, Issue 5, 2021, Pages 629-635]
  • SIRT6 Vitexin ameliorates GCDC-induced hepatocyte injury through SIRT6 and JAK2/STAT3 pathways [Volume 24, Issue 12, 2021, Pages 1717-1725]
  • Sirtuin 1 Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy [Volume 24, Issue 1, 2021, Pages 38-43]
  • Sirtuin 1 Liraglutide ameliorates myocardial damage in experimental diabetic rats by inhibiting pyroptosis via Sirt1/AMPK signaling [Volume 24, Issue 10, 2021, Pages 1358-1365]
  • Sirtuin-1 The impact of moderate-intensity swimming exercise on learning and memory in aged rats: The role of Sirtuin-1 [Volume 24, Issue 10, 2021, Pages 1413-1420]
  • Sirtuin3 Sirtuin 3 deficiency promotes acute kidney injury induced by sepsis via mitochondrial dysfunction and apoptosis [Volume 24, Issue 5, 2021, Pages 675-681]
  • SLC39A6 Development of camelid monoclonal nanobody against SLC39A6 zinc transporter protein [Volume 24, Issue 12, 2021, Pages 1726-1733]
  • Sleep deprivation Neurochemical effects of sleep deprivation in the hippocampus of the pilocarpine-induced rat model of epilepsy [Volume 24, Issue 1, 2021, Pages 85-91]
  • SMA CCL4 HIF L-Carnitine ameliorates the liver by regulating alpha-SMA, iNOS, HSP90, HIF-1alpha, and RIP1 expressions of CCL4-toxic rats [Volume 24, Issue 2, 2021, Pages 184-190]
  • SMAC mimetic The SMAC mimetic AT-101 exhibits anti-tumor and anti-metastasis activity in lung adenocarcinoma cells by the IAPs/ caspase-dependent apoptosis and p65-NFƙB cross-talk [Volume 24, Issue 7, 2021, Pages 969-977]
  • Sodium alginate Sustained release of linezolid in ocular insert based on lipophilic modified structure of sodium alginate [Volume 24, Issue 3, 2021, Pages 331-340]
  • Sodium alginate Evaluation of debridement effects of bromelain-loaded sodium alginate nanoparticles incorporated into chitosan hydrogel in animal models [Volume 24, Issue 10, 2021, Pages 1404-1412]
  • Sodium Dodecyl Sulfate-PAGE Isolation, characterization, and effectiveness of bacteriophage Pɸ-Bw-Ab against XDR Acinetobacter baumannii isolated from nosocomial burn wound infection [Volume 24, Issue 9, 2021, Pages 1254-1263]
  • Solanum melongena Effect of eggplant (Solanum melongena) on the metabolic syndrome: A review [Volume 24, Issue 4, 2021, Pages 420-427]
  • Sophora alopecuroides Antibacterial activity of honeys and potential synergism of honeys with antibiotics and alkaloid extract of Sophora alopecuroides plant against antibiotic-resistant Escherichia coli mutant [Volume 24, Issue 5, 2021, Pages 623-628]
  • SoxS Antibacterial activity of honeys and potential synergism of honeys with antibiotics and alkaloid extract of Sophora alopecuroides plant against antibiotic-resistant Escherichia coli mutant [Volume 24, Issue 5, 2021, Pages 623-628]
  • Spatial cognition Thymoquinone improves cognitive and hippocampal long-term potentiation deficits due to hepatic encephalopathy in rats [Volume 24, Issue 7, 2021, Pages 881-891]
  • Spatial Memory Improved spatial memory, neurobehavioral outcomes, and neuroprotective effect after progesterone administration in ovariectomized rats with traumatic brain injury: Role of RU486 progesterone receptor antagonist [Volume 24, Issue 3, 2021, Pages 349-359]
  • Spectroscopy Description of the calf thymus DNA-malathion complex behavior by multi-spectroscopic and molecular modeling techniques: EMF at low and high frequency approaches [Volume 24, Issue 10, 2021, Pages 1346-1357]
  • Spectroscopy Impact of linker histone in the formation of ambochlorin-calf thymus DNA complex: Multi-spectroscopic, stopped-flow, and molecular modeling approaches [Volume 24, Issue 11, 2021, Pages 1568-1582]
  • Sperm Sperm and testicular dysfunction during cecal ligation and puncture-induced sepsis in male rats and effects of tannic acid through reducing testicular oxidative stress and inflammation [Volume 24, Issue 11, 2021, Pages 1554-1560]
  • Sperm malformations Voluntary exercise could reduce sperm malformations by improving hypothalamus-hypophysis-gonadal axis and kisspeptin/leptin signaling in type 2 diabetic rats [Volume 24, Issue 12, 2021, Pages 1624-1631]
  • Spinal Cord Adrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons [Volume 24, Issue 7, 2021, Pages 978-985]
  • Spinal cord injury Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy [Volume 24, Issue 1, 2021, Pages 38-43]
  • Sprague-Dawley rats NgR1 pathway expression in cerebral ischemic Sprague-Dawley rats with cognitive impairment [Volume 24, Issue 6, 2021, Pages 767-775]
  • Stability Evaluation of kinetic stability and anti-staphylococcal activity of recombinant LasA protein produced in Escherichia coli [Volume 24, Issue 6, 2021, Pages 851-855]
  • Staphylococcus aureus Time-dependent behavior of the Staphylococcus aureus biofilm following exposure to cold atmospheric pressure plasma [Volume 24, Issue 6, 2021, Pages 744-751]
  • Staphylolysin Evaluation of kinetic stability and anti-staphylococcal activity of recombinant LasA protein produced in Escherichia coli [Volume 24, Issue 6, 2021, Pages 851-855]
  • Stem cells Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase pathways [Volume 24, Issue 9, 2021, Pages 1292-1300]
  • Stem cells A study of the transformation of umbilical cord mesenchymal stem cells by interferon-gamma [Volume 24, Issue 9, 2021, Pages 1203-1210]
  • Stem cells G-CSF augments the neuroprotective effect of conditioned medium of dental pulp stem cells against hypoxic neural injury in SH-SY5Y cells [Volume 24, Issue 12, 2021, Pages 1743-1752]
  • Stem cell transplantation Novel function of Nanos2 in expression of innate immunity genes and its probable roles in maintenance of pluripotency state [Volume 24, Issue 4, 2021, Pages 531-536]
  • Street rabies virus Differential pathogenesis of intracerebral and intramuscular inoculation of street rabies virus and CVS-11 strains in a mouse model [Volume 24, Issue 7, 2021, Pages 943-950]
  • Striatum Effects of morphine and NeuroAid on the expression levels of GluN2A and GluN3A in the hippocampus and striatum of rats [Volume 24, Issue 4, 2021, Pages 469-475]
  • Striatum Effects of prolactin on movement disorders and APOE, GFAP, and PRL receptor gene expression following intracerebral hemorrhage in rats [Volume 24, Issue 12, 2021, Pages 1709-1716]
  • Stroke NgR1 pathway expression in cerebral ischemic Sprague-Dawley rats with cognitive impairment [Volume 24, Issue 6, 2021, Pages 767-775]
  • Substance P Pathogenic role of the SP/ NK1R system in GBM cells through inhibiting the thioredoxin system [Volume 24, Issue 4, 2021, Pages 499-505]
  • Susceptibility MKK4 variants rs3826392 and rs3809728 are associated with susceptibility and clinicopathological features in colorectal cancer patients [Volume 24, Issue 8, 2021, Pages 1033-1040]
  • Swimming exercise The impact of moderate-intensity swimming exercise on learning and memory in aged rats: The role of Sirtuin-1 [Volume 24, Issue 10, 2021, Pages 1413-1420]
  • Synergism Quercetin synergistically potentiates the anti-metastatic effect of 5-fluorouracil on the MDA-MB-231 breast cancer cell line [Volume 24, Issue 7, 2021, Pages 928-934]
  • Synthesis Synthesis and biological evaluation of novel quinoline analogs of ketoprofen as multidrug resistance protein 2 (MRP2) inhibitors [Volume 24, Issue 6, 2021, Pages 815-824]

T

  • Target Different microRNAs contribute to the protective effect of mesenchymal stem cell-derived microvesicles in LPS induced acute respiratory distress syndrome [Volume 24, Issue 12, 2021, Pages 1702-1708]
  • Targeted therapy Development and immunohistochemical characterization of patient-derived xenograft models for muscle invasive bladder cancer [Volume 24, Issue 12, 2021, Pages 1650-1655]
  • TBI Improved spatial memory, neurobehavioral outcomes, and neuroprotective effect after progesterone administration in ovariectomized rats with traumatic brain injury: Role of RU486 progesterone receptor antagonist [Volume 24, Issue 3, 2021, Pages 349-359]
  • Technetium-99m Synthesis and evaluation of 99mTc-DOTA-ARA-290 as potential SPECT tracer for targeting cardiac ischemic region [Volume 24, Issue 11, 2021, Pages 1488-1499]
  • Telomerase Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involved [Volume 24, Issue 6, 2021, Pages 842-850]
  • Telomerase In search of elixir: Pharmacological agents against stem cell senescence [Volume 24, Issue 7, 2021, Pages 868-880]
  • Telomerase Mesenchymal stem cells promote caspase-3 expression of SH-SY5Y neuroblastoma cells via reducing telomerase activity and telomere length [Volume 24, Issue 11, 2021, Pages 1583-1589]
  • Telomere Mesenchymal stem cells promote caspase-3 expression of SH-SY5Y neuroblastoma cells via reducing telomerase activity and telomere length [Volume 24, Issue 11, 2021, Pages 1583-1589]
  • Tertiary butylhydroquinone Tertiary butylhydroquinone alleviated liver steatosis and increased cell survival via β-arrestin-2/PI3K/AKT pathway [Volume 24, Issue 10, 2021, Pages 1428-1436]
  • Testicular dysfunction Sperm and testicular dysfunction during cecal ligation and puncture-induced sepsis in male rats and effects of tannic acid through reducing testicular oxidative stress and inflammation [Volume 24, Issue 11, 2021, Pages 1554-1560]
  • Testis Protective effects of selenium on electromagnetic field-induced apoptosis, aromatase P450 activity, and leptin receptor expression in rat testis [Volume 24, Issue 3, 2021, Pages 322-330]
  • Testis Formation of organoid-like structures in the decellularized rat testis [Volume 24, Issue 11, 2021, Pages 1523-1528]
  • TGF-Beta 1 Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease [Volume 24, Issue 6, 2021, Pages 734-743]
  • TGF-β M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system [Volume 24, Issue 11, 2021, Pages 1602-1612]
  • Th1 Game theory applications in host-microbe interactions toward disease manifestation: Mycobacterium tuberculosis infection as an example [Volume 24, Issue 10, 2021, Pages 1324-1335]
  • Thiazole Cytotoxicity and pro‐apoptosis activity of synthetic 1,3-thiazole incorporated phthalimide derivatives on cancer cells [Volume 24, Issue 5, 2021, Pages 604-614]
  • Thioacetamide Thymoquinone improves cognitive and hippocampal long-term potentiation deficits due to hepatic encephalopathy in rats [Volume 24, Issue 7, 2021, Pages 881-891]
  • Thioredoxin Pathogenic role of the SP/ NK1R system in GBM cells through inhibiting the thioredoxin system [Volume 24, Issue 4, 2021, Pages 499-505]
  • Thioredoxin Reductase Telomerase activator-65 and pomegranate peel improved the health status of the liver in aged rats; multi-targets involved [Volume 24, Issue 6, 2021, Pages 842-850]
  • Thymoquinone Effect of orally-administrated thymoquinone during pregnancy on litter size, pentylenetetrazol-induced seizure, and body weight in rat offspring [Volume 24, Issue 1, 2021, Pages 30-37]
  • Thymoquinone Thymoquinone improves cognitive and hippocampal long-term potentiation deficits due to hepatic encephalopathy in rats [Volume 24, Issue 7, 2021, Pages 881-891]
  • Time PCR Sanger sequencing TGF Non-collagenous extracellular matrix protein dermatopontin may play a role as another component of transforming growth factor-β signaling pathway in colon carcinogenesis [Volume 24, Issue 4, 2021, Pages 444-450]
  • Tissue plasminogen - activator Ischemic post-conditioning is neuroprotective even at delayed tPA administration after embolic stroke in female rats [Volume 24, Issue 12, 2021, Pages 1676-1682]
  • TLR4 Flower extract of Caragana sinica. ameliorates Dss-induced ulcerative colitis by affecting TLR4/NF-κB and TLR4/MAPK signaling pathway in a mouse model [Volume 24, Issue 5, 2021, Pages 595-603]
  • TNF-α Protective effect of cannabinoids on gastric mucosal lesions induced by water immersion restrain stress in rats [Volume 24, Issue 9, 2021, Pages 1182-1189]
  • TOF Peptides Vaccine 2 Evaluation of the designed multi-epitope protein of Brucella melitensis in guinea pigs [Volume 24, Issue 6, 2021, Pages 833-841]
  • Tolerogenic dendritic cell Inhibitory effects of tolerogenic probiotics on migratory potential of lupus patient-derived DCs [Volume 24, Issue 11, 2021, Pages 1509-1514]
  • Torsion Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation [Volume 24, Issue 7, 2021, Pages 935-942]
  • Transfection Effect of transgenic Leishmania major expressing mLLO-Bax-Smac fusion gene in the apoptosis of the infected macrophages [Volume 24, Issue 12, 2021, Pages 1666-1675]
  • Transfection G-CSF augments the neuroprotective effect of conditioned medium of dental pulp stem cells against hypoxic neural injury in SH-SY5Y cells [Volume 24, Issue 12, 2021, Pages 1743-1752]
  • Transient receptor potential V1 Transient receptor potential V1 modulates neuroinflammation in Parkinson’s disease dementia: Molecular implications for electroacupuncture and rivastigmine [Volume 24, Issue 10, 2021, Pages 1336-1345]
  • Traumatic brain injuries Huperzine A protects against traumatic brain injury through anti-oxidative effects via the Nrf2-ARE pathway [Volume 24, Issue 10, 2021, Pages 1455-1461]
  • Tricine Effect of using different co-ligands during 99mTc-labeling of J18 peptide on SK-MES-1 cell binding and tumor targeting [Volume 24, Issue 9, 2021, Pages 1240-1246]
  • Tuberculosis Rifampicin-resistant tuberculosis in Iran: A systematic review and meta-analysis [Volume 24, Issue 6, 2021, Pages 720-725]
  • Tuberculosis Game theory applications in host-microbe interactions toward disease manifestation: Mycobacterium tuberculosis infection as an example [Volume 24, Issue 10, 2021, Pages 1324-1335]
  • Type 2 diabetes Interaction of miR-146a-5p with oxidative stress and inflammation in complications of type 2 diabetes mellitus in male rats: antioxidant and anti-inflammatory protection strategies in type 2 diabetic retinopathy [Volume 24, Issue 8, 2021, Pages 1078-1086]
  • Type 2 diabetes mellitus Tertiary butylhydroquinone alleviated liver steatosis and increased cell survival via β-arrestin-2/PI3K/AKT pathway [Volume 24, Issue 10, 2021, Pages 1428-1436]
  • Tyrosine hydroxylase Neuroprotective effects of Wharton’s jelly-derived mesenchymal stem cells on motor deficits due to Parkinson’s disease [Volume 24, Issue 9, 2021, Pages 1173-1181]

U

  • Ulcer Protective effect of cannabinoids on gastric mucosal lesions induced by water immersion restrain stress in rats [Volume 24, Issue 9, 2021, Pages 1182-1189]
  • Ulcerative colitis Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-κB, inflammatory cytokines, iNOS, and oxidative stress [Volume 24, Issue 3, 2021, Pages 312-321]
  • Ulcerative colitis Flower extract of Caragana sinica. ameliorates Dss-induced ulcerative colitis by affecting TLR4/NF-κB and TLR4/MAPK signaling pathway in a mouse model [Volume 24, Issue 5, 2021, Pages 595-603]
  • Unilateral ureteral obstruction Verbascoside alleviates renal fibrosis in unilateral ureteral obstruction rats by inhibiting macrophage infiltration [Volume 24, Issue 6, 2021, Pages 752-759]
  • Urapidil Urapidil alleviates ovarian torsion detorsion injury via regulating oxidative stress, apoptosis, autophagia, and inflammation [Volume 24, Issue 7, 2021, Pages 935-942]
  • Urinary tract infections Type1 and 3 fimbriae phenotype and genotype as suitable markers for uropathogenic bacterial pathogenesis via attachment, cell surface hydrophobicity, and biofilm formation in catheter-associated urinary tract infections (CAUTIs) [Volume 24, Issue 8, 2021, Pages 1098-1106]
  • Uropathogenic Type1 and 3 fimbriae phenotype and genotype as suitable markers for uropathogenic bacterial pathogenesis via attachment, cell surface hydrophobicity, and biofilm formation in catheter-associated urinary tract infections (CAUTIs) [Volume 24, Issue 8, 2021, Pages 1098-1106]
  • UTI Correlation between antibiotic resistance and phylogenetic types among multidrug-resistant Escherichia coli isolated from urinary tract infections [Volume 24, Issue 3, 2021, Pages 400-407]

V

  • Vaccine Evaluation of Helicobacter pylori OipA protein as a vaccine candidate and propolis as an adjuvant in C57BL/6 mice [Volume 24, Issue 9, 2021, Pages 1220-1230]
  • Vaccine Allogeneic tumor cell line-based vaccines: A good alternative to autologous and cancer stem cell vaccines in colorectal cancer [Volume 24, Issue 9, 2021, Pages 1231-1239]
  • Vaccine Effect of transgenic Leishmania major expressing mLLO-Bax-Smac fusion gene in the apoptosis of the infected macrophages [Volume 24, Issue 12, 2021, Pages 1666-1675]
  • Vaccine candidate Preparation and evaluation of the exotoxin A nano-gold conjugate as a vaccine candidate for Pseudomonas aeruginosa infections [Volume 24, Issue 10, 2021, Pages 1366-1372]
  • Valsartan Design and physico-mechanical evaluation of fast-dissolving valsartan polymeric drug delivery system by electrospinning method [Volume 24, Issue 12, 2021, Pages 1683-1694]
  • Variants MKK4 variants rs3826392 and rs3809728 are associated with susceptibility and clinicopathological features in colorectal cancer patients [Volume 24, Issue 8, 2021, Pages 1033-1040]
  • Vascular endothelial growth factor receptor 2 Therapeutic potential of mesenchymal stem cells for peripheral artery disease in a rat model of hindlimb ischemia [Volume 24, Issue 6, 2021, Pages 805-814]
  • VEGF MicroRNAs may provide new strategies in the treatment and diagnosis of diabetic retinopathy: Importance of VEGF [Volume 24, Issue 3, 2021, Pages 267-279]
  • Verbascoside Verbascoside alleviates renal fibrosis in unilateral ureteral obstruction rats by inhibiting macrophage infiltration [Volume 24, Issue 6, 2021, Pages 752-759]
  • VHH library Development of camelid monoclonal nanobody against SLC39A6 zinc transporter protein [Volume 24, Issue 12, 2021, Pages 1726-1733]
  • Virulence genes Antimicrobial resistance patterns, virulence gene profiles, and genetic diversity of Salmonella enterica serotype Enteritidis isolated from patients with gastroenteritis in various Iranian cities [Volume 24, Issue 7, 2021, Pages 914-921]
  • Viscosity Description of the calf thymus DNA-malathion complex behavior by multi-spectroscopic and molecular modeling techniques: EMF at low and high frequency approaches [Volume 24, Issue 10, 2021, Pages 1346-1357]
  • Vitamin B12 Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosis [Volume 24, Issue 2, 2021, Pages 256-263]
  • Vitamin D3 The combination of vitamin D3 and erythropoietin alleviates acute kidney injury induced by ischemia-reperfusion via inhibiting inflammation and apoptosis [Volume 24, Issue 2, 2021, Pages 167-174]
  • Vitexin Vitexin ameliorates GCDC-induced hepatocyte injury through SIRT6 and JAK2/STAT3 pathways [Volume 24, Issue 12, 2021, Pages 1717-1725]
  • Voluntary exercise Voluntary exercise could reduce sperm malformations by improving hypothalamus-hypophysis-gonadal axis and kisspeptin/leptin signaling in type 2 diabetic rats [Volume 24, Issue 12, 2021, Pages 1624-1631]
  • Von Willebrand factor Therapeutic potential of mesenchymal stem cells for peripheral artery disease in a rat model of hindlimb ischemia [Volume 24, Issue 6, 2021, Pages 805-814]

W

  • Whole exome sequencing PLA2G6 gene mutation and infantile neuroaxonal degeneration; report of three cases from Iran [Volume 24, Issue 9, 2021, Pages 1190-1195]
  • Withania somnifera Anti-arthritic activity of Ricinus communis L. and Withania somnifera L. extracts in adjuvant-induced arthritic rats via modulating inflammatory mediators and subsiding oxidative stress [Volume 24, Issue 7, 2021, Pages 951-961]
  • Wound Propranolol-loaded electrospun nanofibrous wound dressing: From fabrication and characterization to preliminary wound healing evaluation [Volume 24, Issue 9, 2021, Pages 1279-1291]
  • Wound infections Isolation, characterization, and effectiveness of bacteriophage Pɸ-Bw-Ab against XDR Acinetobacter baumannii isolated from nosocomial burn wound infection [Volume 24, Issue 9, 2021, Pages 1254-1263]

X

  • Xpert MTB/RIF assay Rifampicin-resistant tuberculosis in Iran: A systematic review and meta-analysis [Volume 24, Issue 6, 2021, Pages 720-725]

Z

  • Zerumbone Zerumbone mediates apoptosis and induces secretion of proinflammatory cytokines in breast carcinoma cell culture [Volume 24, Issue 11, 2021, Pages 1538-1545]